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Spencer Z. Rosero, M.D.

Contact Information

Phone Numbers

Appointment: (585) 275-2475

Office: (585) 275-4775

Fax: (585) 242-9549

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting



Dr. Rosero is a heart rhythm specialist providing care for patients with cardiac arrhythmias including atrial fibrillation, and ventricular tachycardia. He performs ablation of complex arrhythmias including atrial fibrillation and high-risk ventricular tachycardia. Dr. Rosero is an expert in complete management of pacemakers, defibrillators, and resynchronization devices. He is board certified in Internal Medicine, Cardiovascular Disease and Clinical Cardiac Electrophysiology.

Professional Background

Dr. Spencer Z. Rosero is Professor of Medicine at the University of Rochester School of Medicine and Dentistry. He currently serves as Interim Chief of Cardiology . Until recently, he served as the Director of the Clinical Research Center at the Clinical and Translational Sciences Institute (CTSI). and previously served as Clinical Director of the Center for Medical Technology and Innovation at the University of Rochester, an M.S. degree program in Biomedical Engineering through the Department of Biomedical Engineering providing students with specialized training in medical device design. He obtained his medical degree at the State University of New York Health Sciences Center Brooklyn and holds an M.S. degree in Pharmacology from the University of Rochester. Dr. Rosero completed his internal medicine, cardiology and electrophysiology fellowship training including the completion of the ABIM Clinical Investigator Pathway.

Dr. Rosero's research interests focuses on better understanding hereditary arrhythmias such as Long QT syndrome and on futuristic technologies, specifically multi-modal implantable and wearable sensors, that further the personalization of medicine. Dr. Rosero's interests include the translation of medical device-machine acquired data into clinically relevant biomarkers, with a focus on precision medicine. He has several issued and pending patents in his field and is currently developing an implantable biosensor that uses living cells embedded within the chip to provide real-time in-vivo monitoring of biological processes.



Post-doctoral Training & Residency

07/01/1995 - 06/30/2000
Fellowship in Cardiovascular Disease at University of Rochester Medical Center

06/01/1994 - 06/30/1996
Residency in Internal Medicine at University of Rochester Medical Center

06/01/1993 - 06/30/1994
Internship in Internal Medicine at University of Rochester Medical Center

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Patient and Family Centered Care Top Performer Award

Heath Care Achievement Award for Innovation
Sponsor: Rochester Business Journal


Patent Title: System and Method for Stimulation of Biologic Signals in a Bio-Electro-Physiologic Matrix
Patent #: 8,024,020
Issue Date: Sep 20, 2011
Country: United States
Invented By: Spencer Z Rosero

Patent Title: Leadless Implantable Intravascular Electrophysiological Device for Neurologic/Cardiovascular Sensing and Stimulation
Patent #: 8,938,300
Issue Date: Jan 20, 2015
Country: United States
Invented By: Spencer Z Rosero

Patent Title: Implantable Bio-Electro-Physiologic Interface Matrix
Patent #: 8,849,416
Issue Date: Sep 30, 2014
Country: United States
Invented By: Spencer Z Rosero

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Journal Articles

Rosero SZ, Younis A, Jones P, McNitt S, Goldenberg I, Zareba W, Stein K, Kutyifa V. "Utility of Cardiovascular Implantable Electronic Device-Derived Patient Activity to Predict Clinical Outcomes." Heart rhythm.. 2021 Apr 19; Epub 2021 Apr 19.

Younis A, Aktas MK, Rosero S, Kutyifa V, Polonsky B, McNitt S, Sotoodehnia N, Kudenchuk P, Rea TD, Arking DE, Goldenberg I, Zareba W. "Outcome by Sex in Patients With Long QT Syndrome With an Implantable Cardioverter Defibrillator." Journal of the American Heart Association.. 2020 Oct 20; 9(19):e016398. Epub 2020 Sep 21.

Heatwole C, Luebbe E, Rosero S, Eichinger K, Martens W, Hilbert J, Dekdebrun J, Dilek N, Zizzi C, Johnson N, Puwanant A, Tawil R, Schifitto G, Beck CA, Richeson JF, Zareba W, Thornton C, McDermott MP, Moxley R. "Mexiletine in myotonic dystrophy type-1: A randomized, double-blind, placebo-controlled trial." Neurology.. 2020 Oct 12; Epub 2020 Oct 12.

Books & Chapters

Chapter Title: Tachycardias
Book Title: 2001 Conns Current Therapy
Author List: Daubert JP, Rosero SZ, Corsello A.
Edited By: Raker RE, Bope ET
Published By: W.B. Saunders 2001 in Philadelphia, PA




URMC First in Nation to Implant St. Jude HeartPod Heart Failure Device


URMC First in Nation to Implant St. Jude HeartPod Heart Failure Device


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