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R James White III, M.D., Ph.D.


Showing all 33 journal articles & 0 books available

Journal Articles

Lachant DJ, Light AN, Mackin ML, Schwartz RG, White RJ. "Heart Rate Expenditure Correlates with Right Ventricular Function." Annals of the American Thoracic Society.. 2019 Nov 4; Epub 2019 Nov 04.

Lachant DJ, Meoli DF, Haight D, Staicu S, Akers S, Glickman S, Ambrosini R, Champion HC, White RJ. "Combination therapy improves vascular volume in female rats with pulmonary hypertension." American journal of physiology. Lung cellular and molecular physiology.. 2019 Oct 1; 317(4):L445-L455. Epub 2019 Jul 19.

White RJ, Vonk-Noordegraaf A, Rosenkranz S, Oudiz RJ, McLaughlin VV, Hoeper MM, Grünig E, Ghofrani HA, Chakinala MM, Barberà JA, Blair C, Langley J, Frost AE. "Clinical outcomes stratified by baseline functional class after initial combination therapy for pulmonary arterial hypertension." Respiratory research.. 2019 Sep 12; 20(1):208. Epub 2019 Sep 12.

White RJ, Parikh K, Allen R, Feldman J, Jerjez-Sanchez C, Pan L, Keogh AM, Vizza CD, Shapiro SM, Gordon K, Broderick M, Bartolome S. "EXPRESS: Long term study of oral treprostinil to treat pulmonary arterial hypertension: dosing, tolerability, and pharmacokinetics." Pulmonary circulation.. 2019 Jul 10; :2045894019866335. Epub 2019 Jul 10.

Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, Ross RVM, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Noordegraaf AV, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Soubrier F, Trégouët DA, Prokopenko I, Kittles R, Gräf S, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR, , , . "Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis." The Lancet. Respiratory medicine.. 2018 Dec 5; Epub 2018 Dec 05.

Burger CD, Ozbay AB, Lazarus HM, Riehle E, Montejano LB, Lenhart G, White RJ. "Treatment Patterns and Associated Health Care Costs Before and After Treatment Initiation Among Pulmonary Arterial Hypertension Patients in the United States." Journal of managed care & specialty pharmacy.. 2018 Aug; 24(8):834-842. Epub 2018 Feb 13.

White RJ, Wilkins MR. "New Therapeutic Approaches in Pulmonary Arterial Hypertension: The Pantheon Is Getting Crowded." Circulation.. 2018 May 29; 137(22):2390-2392.

Lachant DJ, Meoli DF, Haight D, Lyons JA, Swarthout RF, White RJ. "Low dose monocrotaline causes a selective pulmonary vascular lesion in male and female pneumonectomized rats." Experimental lung research.. 2018 Feb; 44(1):51-61. Epub 2018 Jan 30.

Light A, Heininger A, Wessman K, Frutiger K, White RJ. "8% Capsaicin Patch as Analgesia for Severe Treprostinil Infusion Site Pain." Pain medicine : the official journal of the American Academy of Pain Medicine.. 2017 Dec 1; 18(12):2515-2517.

Rahaghi FF, Feldman JP, Allen RP, Tapson V, Safdar Z, Balasubramanian VP, Shapiro S, Mathier MA, Elwing JM, Chakinala MM, White RJ. "Recommendations for the use of oral treprostinil in clinical practice: a Delphi consensus project pulmonary circulation." Pulmonary circulation.. 2017 Mar; 7(1):167-174. Epub 2017 Mar 21.

Chakinala MM, Feldman JP, Rischard F, Mathier M, Broderick M, Leedom N, Laliberte K, White RJ. "Transition from parenteral to oral treprostinil in pulmonary arterial hypertension." The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.. 2017 Feb; 36(2):193-201. Epub 2016 Jun 24.

Hoeper MM, McLaughlin VV, Barberá JA, Frost AE, Ghofrani HA, Peacock AJ, Simonneau G, Rosenkranz S, Oudiz RJ, White RJ, Miller KL, Langley J, Harris JH, Blair C, Rubin LJ, Vachiery JL. "Initial combination therapy with ambrisentan and tadalafil and mortality in patients with pulmonary arterial hypertension: a secondary analysis of the results from the randomised, controlled AMBITION study." The Lancet. Respiratory medicine.. 2016 Nov; 4(11):894-901. Epub 2016 Oct 11.

White RJ, Rao Y. "Novel Analysis of the Oral Treprostinil Combination Therapy Trial Data." American journal of respiratory and critical care medicine.. 2016 Jun 15; 193(12):1434-6.

White RJ. "Estrogen: Friend or Foe in Pulmonary Hypertension?" American journal of respiratory and critical care medicine.. 2016 May 15; 193(10):1084-6.

Crosby A, Soon E, Jones FM, Southwood MR, Haghighat L, Toshner MR, Raine T, Horan I, Yang P, Moore S, Ferrer E, Wright P, Ormiston ML, White RJ, Haight DA, Dunne DW, Morrell NW. "Hepatic Shunting of Eggs and Pulmonary Vascular Remodeling in Bmpr2(+/-) Mice with Schistosomiasis." American journal of respiratory and critical care medicine.. 2015 Dec 1; 192(11):1355-65.

Galiè N, Barberà JA, Frost AE, Ghofrani HA, Hoeper MM, McLaughlin VV, Peacock AJ, Simonneau G, Vachiery JL, Grünig E, Oudiz RJ, Vonk-Noordegraaf A, White RJ, Blair C, Gillies H, Miller KL, Harris JH, Langley J, Rubin LJ, . "Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension." The New England journal of medicine.. 2015 Aug 27; 373(9):834-44.

Schlosser K, McIntyre LA, White RJ, Stewart DJ. "Customized Internal Reference Controls for Improved Assessment of Circulating MicroRNAs in Disease." PloS one.. 2015 10(5):e0127443. Epub 2015 May 26.

Lannan KL, Phipps RP, White RJ. "Thrombosis, platelets, microparticles and PAH: more than a clot." Drug discovery today.. 2014 Aug; 19(8):1230-5. Epub 2014 Apr 18.

White RJ, Lannan KL, Phipps RP. "Drug discovery in pulmonary arterial hypertension: attacking the enigmatic root of a deadly weed." Drug discovery today.. 2014 Aug; 19(8):1226-9. Epub 2014 Apr 21.

White RJ, Levin Y, Wessman K, Heininger A, Frutiger K. "Subcutaneous treprostinil is well tolerated with infrequent site changes and analgesics." Pulmonary circulation.. 2013 Sep; 3(3):611-21. Epub 2013 Nov 18.

White RJ, Torres F, Allen R, Jerjes C, Pulido T, Yehle D, Howell M, Laliberte K, Marier J, Tapson VF. "Pharmacokinetics of oral treprostinil sustained release tablets during chronic administration to patients with pulmonary arterial hypertension." Journal of cardiovascular pharmacology.. 2013 Jun; 61(6):474-81.

White RJ, Morrell NW. "Understanding the low penetrance of bone morphogenetic protein receptor 2 gene mutations: another needle in the haystack." Circulation.. 2012 Oct 9; 126(15):1818-20.

Friedman SM, White RJ, Finkelstein SM, Kellam J, Allen EF, Sip AK, Stanton R. "Hip fracture in a patient with severe pulmonary hypertension." Geriatric orthopaedic surgery & rehabilitation.. 2012 Sep; 3(3):135-40.

Ferrantino M, White RJ. "Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertension." Expert opinion on pharmacotherapy.. 2011 Nov; 12(16):2583-93.

Yee M, White RJ, Awad HA, Bates WA, McGrath-Morrow SA, O'Reilly MA. "Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice." The American journal of pathology.. 2011 Jun; 178(6):2601-10. Epub 2011 May 06.

Levin YD, White RJ. "Novel therapeutic approaches in pulmonary arterial hypertension: focus on tadalafil." Drugs of today.. 2011 Feb; 47(2):145-56.

Meoli DF, White RJ. "Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinase." Canadian journal of physiology and pharmacology.. 2010 Aug; 88(8):830-9.

White RJ, Hiremath J. "Rationale for the judicious use of placebos in PAH trials." The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.. 2010 Jul; 29(7):826-7. Epub 2010 May 14.

Meoli DF, White RJ. "Thrombin induces fibronectin-specific migration of pulmonary microvascular endothelial cells: requirement of calcium/calmodulin-dependent protein kinase II." American journal of physiology. Lung cellular and molecular physiology.. 2009 Oct; 297(4):L706-14. Epub 2009 Jul 31.

Pang J, Hoefen R, Pryhuber GS, Wang J, Yin G, White RJ, Xu X, O'Dell MR, Mohan A, Michaloski H, Massett MP, Yan C, Berk BC. "G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development." Circulation.. 2009 Mar 24; 119(11):1524-32. Epub 2009 Mar 09.

Gough MS, White RJ. "Sildenafil therapy is associated with improved hemodynamics in liver transplantation candidates with pulmonary arterial hypertension." Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.. 2009 Jan; 15(1):30-6.

White RJ, Meoli DF, Swarthout RF, Kallop DY, Galaria II, Harvey JL, Miller CM, Blaxall BC, Hall CM, Pierce RA, Cool CD, Taubman MB. "Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension." American journal of physiology. Lung cellular and molecular physiology.. 2007 Sep; 293(3):L583-90. Epub 2007 Jun 22.

White RJ, Galaria II, Harvey J, Blaxall BC, Cool CD, Taubman MB. "Tissue factor is induced in a rodent model of severe pulmonary hypertension characterized by neointimal lesions typical of human disease." Chest.. 2005 Dec; 128(6 Suppl):612S-613S.