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Robert M. Kottmann, M.D.

Publications

Showing all 32 journal articles & 0 books available

Journal Articles

12/24/2022
Kalininskiy A, Rackow AR, Nagel D, Croft D, McGrane-Minton H, Kottmann RM. "Association between weight loss and mortality in idiopathic pulmonary fibrosis." Respiratory research.. 2022 Dec 24; 23(1):377. Epub 2022 Dec 24.

10/8/2022
Rackow AR, Nagel DJ, Zapas G, Clough RS, Sime PJ, Kottmann RM. "The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity." International journal of molecular sciences.. 2022 Oct 8; 23(19)Epub 2022 Oct 08.

8/16/2022
Nagel DJ, Rackow AR, Ku WY, Bell TJ, Sime PJ, Kottmann RM. "Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation and Fibrosis; Potential Implications for Idiopathic Pulmonary Fibrosis." Cells.. 2022 Aug 16; 11(16)Epub 2022 Aug 16.

1/5/2022
Rackow AR, Judge JL, Woller CF, Sime PJ, Kottmann RM. "miR-338-3p Blocks TGF?-Induced Myofibroblast Differentiation through the Induction of PTEN." American journal of physiology. Lung cellular and molecular physiology.. 2022 Jan 5; Epub 2022 Jan 05.

2022
Bell TJ, Nagel DJ, Woeller CF, Kottmann RM. "Ogerin mediated inhibition of TGF-?(1) induced myofibroblast differentiation is potentiated by acidic pH." PloS one.. 2022 17(7):e0271608. Epub 2022 Jul 28.

9/30/2021
Croft DP, Burton DS, Nagel DJ, Bhattacharya S, Falsey AR, Georas SN, Hopke PK, Johnston CJ, Kottmann RM, Litonjua AA, Mariani TJ, Rich DQ, Thevenet-Morrison K, Thurston SW, Utell MJ, McCall MN. "The effect of air pollution on the transcriptomics of the immune response to respiratory infection." Scientific reports.. 2021 Sep 30; 11(1):19436. Epub 2021 Sep 30.

9/17/2020
Rackow AR, Nagel DJ, McCarthy C, Judge J, Lacy S, Freeberg MAT, Thatcher TH, Kottmann RM, Sime PJ. "The Self-fulfilling Prophecy of Pulmonary Fibrosis: A Selective Inspection of Pathologic Signaling Loops." The European respiratory journal.. 2020 Sep 17; Epub 2020 Sep 17.

1/15/2019
Wu EK, Ambrosini RD, Kottmann RM, Ritchlin CT, Schwarz EM, Rahimi H. "Reinterpreting Evidence of Rheumatoid Arthritis-Associated Interstitial Lung Disease to Understand Etiology." Current rheumatology reviews.. 2019 Jan 15; Epub 2019 Jan 15.

12/2018
Lachant DJ, Croft DP, McGrane Minton H, Hardy DJ, Prasad P, Kottmann RM. "The clinical impact of pneumocystis and viral PCR testing on bronchoalveolar lavage in immunosuppressed patients." Respiratory medicine.. 2018 Dec; 145:35-40. Epub 2018 Oct 22.

2018
Judge JL, Nagel DJ, Owens KM, Rackow A, Phipps RP, Sime PJ, Kottmann RM. "Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol." PloS one.. 2018 13(5):e0197936. Epub 2018 May 24.

9/1/2017
Jackson TC, Zhang YV, Sime PJ, Phipps RP, Kottmann RM. "Development of an accurate and sensitive method for lactate analysis in exhaled breath condensate by LC MS/MS." Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.. 2017 Sep 1; 1061-1062:468-473. Epub 2017 Jul 24.

8/2017
Lachant DJ, Croft DP, McGrane Minton H, Prasad P, Kottmann RM. "Nasopharyngeal viral PCR in immunosuppressed patients and its association with virus detection in bronchoalveolar lavage by PCR." Respirology : official journal of the Asian Pacific Society of Respirology.. 2017 Aug; 22(6):1205-1211. Epub 2017 Apr 05.

7/2017
Judge JL, Lacy SH, Ku WY, Owens KM, Hernady E, Thatcher TH, Williams JP, Phipps RP, Sime PJ, Kottmann RM. "The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis." Radiation research.. 2017 Jul; 188(1):35-43. Epub 2017 May 02.

4/2017
Yee M, Domm W, Gelein R, Bentley KL, Kottmann RM, Sime PJ, Lawrence BP, O'Reilly MA. "Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells." American journal of respiratory cell and molecular biology.. 2017 Apr; 56(4):453-464.

12/1/2015
Kottmann RM, Trawick E, Judge JL, Wahl LA, Epa A, Owens KM, Thatcher TH, Phipps RP, Sime PJ. "Pharmacologic inhibition of lactate production prevents myofibroblast differentiation." American journal of physiology. Lung cellular and molecular physiology.. 2015 Dec 1; 309(11):L1305-12. Epub 2015 Sep 25.

10/15/2015
Judge JL, Owens KM, Pollock SJ, Woeller CF, Thatcher TH, Williams JP, Phipps RP, Sime PJ, Kottmann RM. "Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase." American journal of physiology. Lung cellular and molecular physiology.. 2015 Oct 15; 309(8):L879-87. Epub 2015 Aug 07.

10/15/2015
Croasdell A, Thatcher TH, Kottmann RM, Colas RA, Dalli J, Serhan CN, Sime PJ, Phipps RP. "Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages." American journal of physiology. Lung cellular and molecular physiology.. 2015 Oct 15; 309(8):L888-901. Epub 2015 Aug 21.

5/27/2015
Kottmann RM, Sharp J, Owens K, Salzman P, Xiao GQ, Phipps RP, Sime PJ, Brown EB, Perry SW. "Second harmonic generation microscopy reveals altered collagen microstructure in usual interstitial pneumonia versus healthy lung." Respiratory research.. 2015 May 27; 16:61. Epub 2015 May 27.

4/2015
Jones KM, Randtke EA, Howison CM, Cárdenas-Rodríguez J, Sime PJ, Kottmann MR, Pagel MD. "Measuring extracellular pH in a lung fibrosis model with acidoCEST MRI." Molecular imaging and biology.. 2015 Apr; 17(2):177-84.

2015
Epa AP, Thatcher TH, Pollock SJ, Wahl LA, Lyda E, Kottmann RM, Phipps RP, Sime PJ. "Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-? Induced Myofibroblast Differentiation via Prostaglandin E2." PloS one.. 2015 10(8):e0135266. Epub 2015 Aug 06.

4/2014
Olsen KC, Epa AP, Kulkarni AA, Kottmann RM, McCarthy CE, Johnson GV, Thatcher TH, Phipps RP, Sime PJ. "Inhibition of transglutaminase 2, a novel target for pulmonary fibrosis, by two small electrophilic molecules." American journal of respiratory cell and molecular biology.. 2014 Apr; 50(4):737-47.

10/1/2013
Rosas IO, Kottman RM, Sime PJ. "New light is shed on the enigmatic origin of the lung myofibroblast." American journal of respiratory and critical care medicine.. 2013 Oct 1; 188(7):765-6.

2013
Kulkarni AA, Thatcher TH, Hsiao HM, Olsen KC, Kottmann RM, Morrissette J, Wright TW, Phipps RP, Sime PJ. "The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis." PloS one.. 2013 8(5):e63798. Epub 2013 May 31.

10/15/2012
Kottmann RM, Kulkarni AA, Smolnycki KA, Lyda E, Dahanayake T, Salibi R, Honnons S, Jones C, Isern NG, Hu JZ, Nathan SD, Grant G, Phipps RP, Sime PJ. "Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-?." American journal of respiratory and critical care medicine.. 2012 Oct 15; 186(8):740-51. Epub 2012 Aug 23.

5/2012
Davies ER, Haitchi HM, Thatcher TH, Sime PJ, Kottmann RM, Ganesan A, Packham G, O'Reilly KM, Davies DE. "Spiruchostatin A inhibits proliferation and differentiation of fibroblasts from patients with pulmonary fibrosis." American journal of respiratory cell and molecular biology.. 2012 May; 46(5):687-94. Epub 2012 Jan 12.

9/15/2011
Olsen KC, Sapinoro RE, Kottman RM, Kulkarni AA, Iismaa SE, Johnson GV, Thatcher TH, Phipps RP, Sime PJ. "Transglutaminase 2 and its role in pulmonary fibrosis." American journal of respiratory and critical care medicine.. 2011 Sep 15; 184(6):699-707. Epub 2011 Jun 23.

9/2011
Kottmann RM, Kelly J, Lyda E, Gurell M, Stalica J, Ormsby W, Moon K, Trawick D, Sime PJ. "Bronchoscopy with bronchoalveolar lavage: determinants of yield and impact on management in immunosuppressed patients." Thorax.. 2011 Sep; 66(9):823. Epub 2010 Sep 13.

9/2010
Manganaris C, Wittlin S, Xu H, Gurell M, Sime P, Kottmann RM. "Metastatic papillary thyroid carcinoma and severe airflow obstruction." Chest.. 2010 Sep; 138(3):738-42.

11/2009
Ferguson HE, Thatcher TH, Olsen KC, Garcia-Bates TM, Baglole CJ, Kottmann RM, Strong ER, Phipps RP, Sime PJ. "Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism." American journal of physiology. Lung cellular and molecular physiology.. 2009 Nov; 297(5):L912-9. Epub 2009 Sep 04.

9/2009
Kottmann RM, Hogan CM, Phipps RP, Sime PJ. "Determinants of initiation and progression of idiopathic pulmonary fibrosis." Respirology : official journal of the Asian Pacific Society of Respirology.. 2009 Sep; 14(7):917-33.

9/2/2008
Gurell MN, Kottmann RM, Xu H, Sime PJ. "Exogenous lipoid pneumonia: an unexpected complication of substance abuse." Annals of internal medicine.. 2008 Sep 2; 149(5):364-5.

2007
Lakatos HF, Thatcher TH, Kottmann RM, Garcia TM, Phipps RP, Sime PJ. "The Role of PPARs in Lung Fibrosis." PPAR research. 2007 2007:71323.