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Steven A. Goldman, M.D., Ph.D.

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Phone Numbers

Appointment: (585) 275-1200

Administrative: (585) 276-4595

Fax: (585) 276-2298

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

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Dr. Steven A. Goldman is the URMC Distinguished Professor of Neuroscience and Neurology, and co-Director of Rochester's Center for Translational Neuromedicine. He has a concurrent appointment as Professor of Neuroscience at the University of Copenhagen in Denmark, where he serves as co-director of its sister Center for Translational Neuromedicine, and as Professor of Neuology at its affiliated Copenhagen University Hospital. Goldman moved to Rochester in 2003 from the Weill Medical College of Cornell University, where he was the Nathan Cummings Professor of Neurology, and Attending Neurologist at New York Presbyterian Hospital. A summa cum laude graduate of the University of Pennsylvania, he obtained his PhD with Fernando Nottebohm at the Rockefeller University in 1983, and his MD from Cornell in 1984. Dr. Goldman interned in Medicine and did his residency in Neurology under Fred Plum at New York Hospital-Cornell, and Jerome Posner at the Memorial Sloan-Kettering Cancer Center, before joining the Cornell faculty. Goldman moved to Rochester as the Dean Zutes Chair in Biology of the Aging Brain, and as Chief of the Neurology department's Division of Cell and Gene Therapy; he subsequently served as the founding program director for Rochester's neuro-oncology training program, and served as Chairman of the Department (2008-12). Dr. Goldman remains active clinically, with subspecialty interests in stroke, myelin disease and neuro-oncology.


Goldman is interested in cell genesis and regeneration in the adult brain, with a focus on the use of stem and progenitor cells in both modeling and treating demyelinating and neurodegenerative diseases, including targets as diverse as progressive multiple sclerosis, the leukodystrophies, Huntington Disease and schizophrenia. He also has a strong interest in the conversion of resident cells into brain cancers, and is board certified in neuro-oncology. He has published over 250 papers, over 100 as first or senior author, and holds over 30 patents in his field. Dr. Goldman is a recipient of the Novo Nordisk Foundation Laureate Award, the Jacob Javits Neuroscience Investigator Award of the NIH, and has been elected to Academia Europaea, the Association of American Physicians, the American Society for Clinical Investigation, and the American Neurological Association, and he is a fellow of the American Academy of Neurology. He serves on standing committees of the NIH, and has served as a voting member of the FDA Cellular, Tissue and Gene Therapy Advisory Committee. He is a co-founder of Oscine Therapeutics, and his work is supported by NIH/NINDS, the Adelson Medical Research Foundation, the Mathers Charitable Foundation, the Novo Nordisk Foundation, and the Lundbeck Foundation.



BA | Univ of Pennsylvania

PhD | Rockefeller University

MD | Cornell Univ Medical College

Post-doctoral Training & Residency

7/1984 - 6/1985
Internship in Internal Medicine at Cornell University Medical College

7/1985 - 6/1988
Residency in Neurology at Cornell University Medical College


2002 - 2009
Jacob Javits Neurosci. Investigator Award (NIH)

1998 - 2001
Human Frontiers Scientific Program award

1997 - 2007
National Multiple Sclerosis Soc. Invest. Award

1993 - 1997
Irma T. Hirschl Career Scientist Award

1993 - 1994
American Paralysis Association Award

1992 - 1997
Location: NIH/NINDS

1988 - 1997
Mathers Charitable Foundation Awards

1988 - 1993
Clinical Invest. Development Award
Location: HIH/NINDS

1988 - 1991
Cornell Scholar in Biomedical Science

1978 - 1984
Medical Scientist Training Program
Location: USPHS

Phi Beta Kappa
Location: University of Pennsylvania

1974 - 1978
Benjamin Franklin Scholar, U. of Pennsylvania

1974 - 1978
Mayor's Scholar
Location: City of Philadelphia

1974 - 1978
Senatorial Scholar
Location: State of Pennsylvania

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Title: A Human Glial Chimeric Model for Drug Candidate Assessment in Human Gliotrophic Viral Infections and Progressive Multifocal Encephalopathy
U.S. Serial #: 14/710,144
Filed: May 12, 2015
Invented By: Steven Goldman, Leonid Gorelik, Yoichi Kondo, Martha Windrem


Journal Articles

Mariani JN, Zou L, Goldman SA. "Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease." Methods in molecular biology.. 2019 1936:311-331.

Osipovitch M, Asenjo Martinez A, Mariani JN, Cornwell A, Dhaliwal S, Zou L, Chandler-Militello D, Wang S, Li X, Benraiss SJ, Agate R, Lampp A, Benraiss A, Windrem MS, Goldman SA. "Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation." Cell stem cell.. 2018 Nov 23; Epub 2018 Nov 23.

Barker RA, Carpenter MK, Forbes S, Goldman SA, Jamieson C, Murry CE, Takahashi J, Weir G. "The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?" Stem cell reports.. 2018 May 8; 10(5):1429-1431.