Skip to main content
Explore URMC

Lawrence J. Saubermann, M.D.


Showing all 48 journal articles & 6 books available

Journal Articles

"P047?The Crohn's Disease-Health Index (CD-HI): Development and Validation of a Novel, Disease-Specific Patient Reported Outcome Measure for Clinical Trials." The American journal of gastroenterology.. 2021 Dec 1; 116(Suppl 1):S12.

Park S, Miller J, Cheong J, Ullah A, Saubermann L, Decross A. "Late-Onset Posttransplant Lymphoproliferative Disorder Results in Jejunal Stricture Managed with Endoscopic Dilation." Case reports in gastrointestinal medicine. 2021 2021:5583665. Epub 2021 Aug 03.

Baig A, Avlasevich SL, Torous DK, Bemis JC, Saubermann LJ, Lovell DP, MacGregor JT, Dertinger SD. "Assessment of systemic genetic damage in pediatric inflammatory bowel disease." Environmental and molecular mutagenesis.. 2020 Aug 5; Epub 2020 Aug 05.

Torous DK, Avlasevich SL, Khattab MG, Baig A, Saubermann LJ, Chen Y, Bemis JC, Lovell DP, Walker VE, MacGregor JT, Dertinger SD. "Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation." Environmental and molecular mutagenesis.. 2020 Jun 22; Epub 2020 Jun 22.

Kirby C, Baig A, Avlasevich SL, Torous DK, Tian S, Singh P, Bemis JC, Saubermann LJ, Dertinger SD. "Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays." Mutagenesis.. 2020 Mar 27; 35(2):161-167.

Deneau M, Valentino P, Mack C, Alqoaer K, Amin M, Amir A, Aumar M, Auth M, Broderick A, DiGuglielmo M, Draijer LG, El-Matary W, Ferrari F, Furuya K, Gottrand F, Gupta N, Homan M, Jensen MK, Kamath BM, Kim KM, Kolho KL, Koot BG, Iorio R, Martinez M, Miloh T, Mohan P, Palle S, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Woynarowski M, Guthery S. "Assessing the Validity of Adult-Derived Prognostic Models for Primary Sclerosing Cholangitis Outcomes in Children." Journal of pediatric gastroenterology and nutrition.. 2019 Oct 22; Epub 2019 Oct 22.

Sands BE, Sandborn WJ, Panaccione R, O'Brien CD, Zhang H, Johanns J, Adedokun OJ, Li K, Peyrin-Biroulet L, Van Assche, Danese S, Targan S, Abreu MT, Hisamatsu T, Szapary P, Marano C. "Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis." The New England journal of medicine.. 2019 Sep 26; 381(13):1201-1214.

Deneau M, Perito E, Ricciuto A, Gupta N, Kamath BM, Palle S, Vitola B, Smolka V, Ferrari F, Amir AZ, Miloh T, Papadopoulou A, Mohan P, Mack C, Kolho KL, Iorio R, El-Matary W, Venkat V, Chan A, Saubermann L, Valentino PL, Shah U, Miethke A, Lin H, Jensen MK. "Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis: Predictors of Gamma Glutamyltransferase Normalization and Favorable Clinical Course." The Journal of pediatrics.. 2019 Mar 13; Epub 2019 Mar 13.

Noor M, Katzman PJ, Huber AR, Findeis-Hosey JJ, Whitney-Miller C, Gonzalez RS, Zhou Z, N'kodia HD, Skonick K, Abell RL, Saubermann LJ, Lamps LW, Drage MG. "Unexpectedly High Prevalence of Cystoisospora belli Infection in Acalculous Gallbladders of Immunocompetent Patients." American journal of clinical pathology.. 2019 Jan 1; 151(1):100-107.

Deneau MR, Mack C, Abdou R, Amin M, Amir A, Auth M, Bazerbachi F, Marie Broderick A, Chan A, DiGuglielmo M, El-Matary W, El-Youssef M, Ferrari F, Furuya KN, Gottrand F, Gupta N, Homan M, Jensen MK, Kamath BM, Mo Kim K, Kolho KL, Konidari A, Koot B, Iorio R, Martinez M, Mohan P, Palle S, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Valentino PL, Varier R, Venkat V, Vitola B, Vos MB, Woynarowski M, Yap J, Miloh T. "Gamma Glutamyltransferase Reduction Is Associated With Favorable Outcomes in Pediatric Primary Sclerosing Cholangitis." Hepatology communications.. 2018 Nov; 2(11):1369-1378. Epub 2018 Sep 25.

Deneau MR, El-Matary W, Valentino PL, Abdou R, Alqoaer K, Amin M, Amir AZ, Auth M, Bazerbachi F, Broderick A, Chan A, Cotter J, Doan S, El-Youssef M, Ferrari F, Furuya KN, Gottrand M, Gottrand F, Gupta N, Homan M, Kamath BM, Kim KM, Kolho KL, Konidari A, Koot B, Iorio R, Ledder O, Mack C, Martinez M, Miloh T, Mohan P, O'Cathain N, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Vos MB, Woynarowski M, Yap J, Jensen MK. "The natural history of primary sclerosing cholangitis in 781 children: A multicenter, international collaboration." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 2017 Aug; 66(2):518-527. Epub 2017 Jun 26.

Saubermann LJ, Deneau M, Falcone RA, Murray KF, Ali S, Kohli R, Ekong UD, Valentino PL, Grossman AB, Rand EB, Jonas MM, Saeed SA, Kamath BM. "Hepatic Issues and Complications Associated With Inflammatory Bowel Disease: A Clinical Report From the NASPGHAN Inflammatory Bowel Disease and Hepatology Committees." Journal of pediatric gastroenterology and nutrition.. 2017 Apr; 64(4):639-652.

Feagan BG, Sandborn WJ, Gasink C, Jacobstein D, Lang Y, Friedman JR, Blank MA, Johanns J, Gao LL, Miao Y, Adedokun OJ, Sands BE, Hanauer SB, Vermeire S, Targan S, Ghosh S, de Villiers WJ, Colombel JF, Tulassay Z, Seidler U, Salzberg BA, Desreumaux P, Lee SD, Loftus EV, Dieleman LA, Katz S, Rutgeerts P, . "Ustekinumab as Induction and Maintenance Therapy for Crohn's Disease." The New England journal of medicine.. 2016 Nov 17; 375(20):1946-1960.

Sherman M, Tsynman DN, Kim A, Arora J, Pietras T, Messing S, St Hilaire L, Yoon S, Decross A, Shah A, Saubermann L. "Sustained improvement in health-related quality of life measures in patients with inflammatory bowel disease receiving prolonged anti-tumor necrosis factor therapy." Journal of digestive diseases.. 2014 Apr; 15(4):174-9.

Saubermann, Lawrence J. "Understanding IBD". CAP PC. 2014; : 4 & 8.

Stormont JM, Shah AN, Sharma AK, Saubermann LJ, Farmer RG. "Colorectal cancer in IBD patients." The American journal of gastroenterology.. 2013 Sep; 108(9):1535.

Sandborn WJ, Feagan BG, Rutgeerts P, Hanauer S, Colombel JF, Sands BE, Lukas M, Fedorak RN, Lee S, Bressler B, Fox I, Rosario M, Sankoh S, Xu J, Stephens K, Milch C, Parikh A, . "Vedolizumab as induction and maintenance therapy for Crohn's disease." The New England journal of medicine.. 2013 Aug 22; 369(8):711-21.

Roy A, Gaylo A, Cao W, Saubermann LJ, Lawrence BP. "Neither direct nor developmental exposure to bisphenol A alters the severity of experimental inflammatory colitis in mice." Journal of immunotoxicology.. 2013 10(4):334-40. Epub 2013 Jan 03.

Mohanty PH, Sood V, Saubermann LJ. "A 16-year-old girl with perianal skin tags." Pediatric annals.. 2012 Jun; 41(6):10-2.

Zhang L, Sun W, Wang J, Zhang M, Yang S, Tian Y, Vidyasagar S, Peña LA, Zhang K, Cao Y, Yin L, Wang W, Zhang L, Schaefer KL, Saubermann LJ, Swarts SG, Fenton BM, Keng PC, Okunieff P. "Mitigation effect of an FGF-2 peptide on acute gastrointestinal syndrome after high-dose ionizing radiation." International journal of radiation oncology, biology, physics.. 2010 May 1; 77(1):261-8.

Schaefer KL; Harris G; Jasalavich CA; Morales VM; Saubermann LJ. "PPAR gamma suppresses early phase but increases late phase production of IL-8 in TNFa-stimulated intestinal epithelial cells". To be submitted. 2010; .

Kobayashi N, Inamori M, Fujita K, Fujisawa T, Fujisawa N, Takahashi H, Yoneda M, Abe Y, Kawamura H, Shimamura T, Kirikoshi H, Kubota K, Sakaguchi T, Saito S, Saubermann LJ, Nakajima A. "Characterization of K-ras gene mutations in association with mucinous hypersecretion in intraductal papillary-mucinous neoplasms." Journal of hepato-biliary-pancreatic surgery.. 2008 15(2):169-77. Epub 2008 Apr 06.

Kugathasan S, Saubermann LJ, Smith L, Kou D, Itoh J, Binion DG, Levine AD, Blumberg RS, Fiocchi C. "Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease." Gut.. 2007 Dec; 56(12):1696-705. Epub 2007 Aug 06.

Schaefer KL, Takahashi H, Morales VM, Harris G, Barton S, Osawa E, Nakajima A, Saubermann LJ. "PPARgamma inhibitors reduce tubulin protein levels by a PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells." International journal of cancer.. 2007 Feb 1; 120(3):702-13.

Probert CS, Saubermann LJ, Balk S, Blumberg RS. "Repertoire of the alpha beta T-cell receptor in the intestine." Immunological reviews.. 2007 Feb; 215:215-25.

Takahashi H, Fujita K, Fujisawa T, Yonemitsu K, Tomimoto A, Ikeda I, Yoneda M, Masuda T, Schaefer K, Saubermann LJ, Shimamura T, Saitoh S, Tachibana M, Wada K, Nakagama H, Nakajima A. "Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties." Cancer science.. 2006 Sep; 97(9):854-60. Epub 2006 Jun 29.

Dendrinos KG, Becker JM, Stucchi AF, Saubermann LJ, LaMorte W, Farraye FA. "Anti-Saccharomyces cerevisiae antibodies are associated with the development of postoperative fistulas following ileal pouch-anal anastomosis." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.. 2006 10(7):1060-4.

Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, Wolfe MM, Turner JR, Nakajima A, Borkan SC, Saubermann LJ. "Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells." Cancer research.. 2005 Mar 15; 65(6):2251-9.

Schaefer KL, Denevich S, Ma C, Cooley SR, Nakajima A, Wada K, Schlezinger J, Sherr D, Saubermann LJ. "Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms." Inflammatory bowel diseases.. 2005 Mar; 11(3):244-52.

Wada K, Nakajima A, Takahashi H, Yoneda M, Fujisawa N, Ohsawa E, Kadowaki T, Kubota N, Terauchi Y, Matsuhashi N, Saubermann LJ, Nakajima N, Blumberg RS. "Protective effect of endogenous PPARgamma against acute gastric mucosal lesions associated with ischemia-reperfusion." American journal of physiology. Gastrointestinal and liver physiology.. 2004 Aug; 287(2):G452-8.

Nakajima A, Wada K, Katayama K, Saubermann L, Osawa E, Nagase H, Ueno N, Matsuhashi N, Aburatani H. "Gene expression profile after peroxisome proliferator activator receptor-gamma ligand administration in dextran sodium sulfate mice." Journal of gastroenterology.. 2002 Nov; 37 Suppl 14:62-6.

Saubermann LJ, Nakajima A, Wada K, Zhao S, Terauchi Y, Kadowaki T, Aburatani H, Matsuhashi N, Nagai R, Blumberg RS. "Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis." Inflammatory bowel diseases.. 2002 Sep; 8(5):330-9.

Matsuhashi, N.; Nakajima, A.; Wada, K.; Miki, H.; Saubermann, LJ.; Kubota, N.; Terauchi, Y.; Kadowaki, T.; Nagai, R.; Blumberg, RS. "Protective Effects of PPARy in Gastrointestinal Mucosal Injuries." Immunology. 2002; 4: 227-233.

Probert CS, Chott A, Saubermann LJ, Stevens AC, Balk SP, Blumberg RS. "Prevalence of an ulcerative colitis-associated CD8+ T cell receptor beta-chain CDR3-region motif and its association with disease activity." Journal of clinical immunology.. 2001 Mar; 21(2):126-34.

Nakajima A, Wada K, Miki H, Kubota N, Nakajima N, Terauchi Y, Ohnishi S, Saubermann LJ, Kadowaki T, Blumberg RS, Nagai R, Matsuhashi N. "Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury." Gastroenterology.. 2001 Feb; 120(2):460-9.

Saubermann LJ. "pANCA--is this your final answer?" Inflammatory bowel diseases.. 2000 Nov; 6(4):332-3.

Mizoguchi A, Mizoguchi E, Saubermann LJ, Higaki K, Blumberg RS, Bhan AK. "Limited CD4 T-cell diversity associated with colitis in T-cell receptor alpha mutant mice requires a T helper 2 environment." Gastroenterology.. 2000 Oct; 119(4):983-95.

Saubermann LJ, Beck P, De Jong YP, Pitman RS, Ryan MS, Kim HS, Exley M, Snapper S, Balk SP, Hagen SJ, Kanauchi O, Motoki K, Sakai T, Terhorst C, Koezuka Y, Podolsky DK, Blumberg RS. "Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice." Gastroenterology.. 2000 Jul; 119(1):119-28.

Muehlhoefer A, Saubermann LJ, Gu X, Luedtke-Heckenkamp K, Xavier R, Blumberg RS, Podolsky DK, MacDermott RP, Reinecker HC. "Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa." The Journal of immunology : official journal of the American Association of Immunologists.. 2000 Mar 15; 164(6):3368-76.

Blumberg RS, Saubermann LJ, Strober W. "Animal models of mucosal inflammation and their relation to human inflammatory bowel disease." Current opinion in immunology.. 1999 Dec; 11(6):648-56.

Blumberg RS, Lencer WI, Zhu X, Kim HS, Claypool S, Balk SP, Saubermann LJ, Colgan SP. "Antigen presentation by intestinal epithelial cells." Immunology letters.. 1999 Jun 15; 69(1):7-11.

Saubermann LJ, Wolf JL. "Mesalamine: safe at first look." Inflammatory bowel diseases.. 1999 May; 5(2):148-9.

Saubermann LJ, Probert CS, Christ AD, Chott A, Turner JR, Stevens AC, Balk SP, Blumberg RS. "Evidence of T cell receptor beta-chain patterns in inflammatory and noninflammatory bowel disease states." The American journal of physiology.. 1999 Mar; 276(3):G613-21.

Omata F, Itoh T, Shibayama Y, Ide H, Takahashi H, Ueno F, Saubermann LJ, Matsuzaki S. "Duodenal variceal bleeding treated with a combination of endoscopic ligation and sclerotherapy." Endoscopy.. 1998 Jun; 30(5):S62-3.

Probert CS, Aitken EW, Saubermann LJ, Balk SP, Blumberg RS. "T-cell receptor usage in the intestine." Chemical immunology.. 1998 71:27-39.

Probert CS, Christ AD, Saubermann LJ, Turner JR, Chott A, Carr-Locke D, Balk SP, Blumberg RS. "Analysis of human common bile duct-associated T cells: evidence for oligoclonality, T cell clonal persistence, and epithelial cell recognition." The Journal of immunology : official journal of the American Association of Immunologists.. 1997 Feb 15; 158(4):1941-8.

Probert CS, Chott A, Turner JR, Saubermann LJ, Stevens AC, Bodinaku K, Elson CO, Balk SP, Blumberg RS. "Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease." The Journal of immunology : official journal of the American Association of Immunologists.. 1996 Oct 1; 157(7):3183-91.

Takeda J, Seino Y, Tanaka K, Fukumoto H, Kayano T, Takahashi H, Mitani T, Kurono M, Suzuki T, Tobe T. "Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor." Proceedings of the National Academy of Sciences of the United States of America.. 1987 Oct; 84(20):7005-8.

Books & Chapters

Chapter Title: Ulcerative Colitis
Book Title: Therapies of Digestive Disorders, second edition
Author List: Saubermann LJ; Farraye FA
Edited By: M.W. Wolfe, et al, Eds.
Published By: Elsevier Publishers2006

Chapter Title: Inflammatory Bowel Disease
Book Title: Cecil Essentials of Medicine
Author List: Saubermann, LJ and Farraye, FA.
Edited By: Andreoli TE et al.
Published By: W.B. Saunders Company2003 in Philadelphia

Chapter Title: Immunological Aspects of Gastroenterology
Book Title: Molecular Immunology of Mucosal T Cells
Author List: Saubermann, LJ and Blumberg RS
Published By: Kluwer Academic Press2000

Chapter Title: Molecular Immunology of Mucosal T Cells
Book Title: Immunological Aspects of Gastroenterology
Author List: Saubermann, LJ and Blumberg, RS.
Published By: Kluwer Academic Press2000

Chapter Title: Reproduction and Inflammatory Bowel Disese.
Book Title: Inflammatory Bowel Disease: A Guide for Patients and Their Families
Author List: Saubermann, LJ and Wolf, J.
Edited By: Hanauer SB, Kirsner JB
Published By: Lippincott-Raven Press1998

Chapter Title: T-Cell Receptor Usage in the Intestine
Book Title: Chem Immunology
Author List: Probert CSJ, Aitken EW, Saubermann LJ, Balk SP, Blumberg RS.
Published By: Chem Immunology1998