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Matthew D. McGraw, M.D.

Contact Information

Phone Numbers

Administrative: (585) 275-2464

Fax: (585) 275-8706

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Research Labs

Faculty Appointments

Patient Care Setting

Pediatrics

Biography

Clinical Interests: Childhood Interstitial Lung Diseases (chILD); Bronchiolitis Obliterans (BO); Chronic Lung Disease of Prematurity; Asthma; Cystic Fibrosis

Dr. McGraw's primary goal as a pediatric pulmonologist is the prevention of the early lung function decline in children. His primary area of interest is in the diagnosis and management of rare lung diseases, including childhood interstitial lung disease (chILD) and bronchiolitis obliterans (BO).

Research

Dr. McGraw's research involves understanding the mechanisms of aberrant airway epithelial repair after inhalation injuries. The primary pediatric lung disease studied is bronchiolitis obliterans (BO), a devastating and often progressive fibrotic lung disease characterized by progressive luminal narrowing and obliteration of the small airways, or bronchioles. Despite BO's high morbidity and mortality, very little is known about its pathogenesis, and even less is available in terms of prevention, intervention and treatment.

Inhalation agents used to study the mechanisms of aberrant airway epithelial repair include sulfur mustard (SM), a chemical warfare inhalation agent, and diacetyl, a volatile chemical in many flavorings. Both of these inhalation agents can cause bronchiolitis obliterans in children.

Basic science techniques include: small animal model development; primary airway epithelial cell isolation; flow sorting; 3D cell culture; single cell RNA sequencing.

Credentials

Specialties

  • Pediatrics - American Board of Pediatrics
  • Pediatric Pulmonology - American Board of Pediatrics

Education

2012
MD | Suny Upstate Medical University

Post-doctoral Training & Residency

07/01/2015 - 06/30/2018
Fellowship in Pediatric Pulmonology at University of Colorado Hospital- GME

07/01/2013 - 06/30/2015
Residency in Pediatrics at University of Virginia Children's Hospital

07/01/2012 - 06/30/2013
Internship in Pediatrics at University of Virginia Children's Hospital

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Awards

2020 - 2022
KL2 Award
Sponsor: NCATS and URMC CTSI
Location: University of Rochester, Rochester, NY

2020 - 2021
Furth Award
Sponsor: Office of the Provost, University of Rochester
Location: Rochester, NY

2019 - 2021
NIH Loan Repayment Program
Sponsor: NIEHS
Location: University of Rochester, Rochester, NY

2018
Best Research Poster, Junior Faculty
Sponsor: Department of Pediatrics, Golisano's Children's Hospital
Location: Rochester, NY

2017
Society of Toxicology's Donald E. Gardner Inhalation Toxicology Education Award 2017

2016 - 2018
NIH T32 Training Grant, University of Colorado SOM, 2016 –2018

2015
Mulholland Resident and Fellow Teaching Award, Honorable Mention, 2015

2014 - 2015
American Academy of Pediatrics, Resident CATCH Implementation Grant, 2014 – 2015

2014 - 2015
University of Virginia Pediatrics Resident Teaching Award, 2014 & 2015

2011 - 2012
Gold Humanism Honor Society

2008
Bucknell University Department of Biomedical Engineering, Magna Cum Laude

2007 - 2008
Tau Beta Pi Engineering Honor Society

2005 - 2008
Bucknell University Dean's List

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Publications

Journal Articles

7/16/2020
"Reply to: Lipid Laden Macrophages Are Not Diagnostic of PAP Syndrome and Can Indicate Lung Injury." American journal of respiratory and critical care medicine.. 2020 Jul 16; Epub 2020 Jul 16.

6/28/2020
Muthumalage T, Lucas JH, Wang Q, Lamb T, McGraw MD, Rahman I. "Pulmonary Toxicity and Inflammatory Response of E-Cigarette Vape Cartridges Containing Medium-Chain Triglycerides Oil and Vitamin E Acetate: Implications in the Pathogenesis of EVALI." . 2020 Jun 28; 8(3)Epub 2020 Jun 28.

6/1/2020
McGraw MD, Kim SY, Reed C, Hernady E, Rahman I, Mariani TJ, Finkelstein JN. "Airway basal cell injury after acute diacetyl (2,3-butanedione) vapor exposure." Toxicology letters.. 2020 Jun 1; 325:25-33. Epub 2020 Feb 26.

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