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Szilvia Arany, D.M.D., Ph.D.

Dentistry

Contact Information

Phone Numbers

Appointment: (585) 275-5051

Fax: (585) 273-1235

assignmentAccepting New Patients

Biography

Research on the role of cell-based regeneration of the salivary glands and on gene therapy for radiation-damaged salivary glands

Professional Background

General Practice Residency (GME at University of Rochester, 2016-2017)
Advanced Education in General Dentistry at Eastman Institute of Oral Health, University of Rochester, NY (2013-2016)
PhD in Medical Science, Akita University, Graduate School of Medicine, Japan (2004)
DMD Semmelweis University of Medicine, Hungary (1995)

Research

Received training in general dentistry and in dento-alveolar surgery in Hungary, then completed PhD course in forensic dentistry in Japan. Post-doctoral research fellowship research on the fields of tooth regeneration and salivary gland biology. Laboratory skills include gene and protein expression analysis, microscope imaging techniques, performance of relevant in vivo procedures: salivary gland cannulation and retroductal injection technique (training at NIDCR), regeneration experiments (ductal ligation operation, in vivo irradiation), scaffold-progenitor implantation (training in Japan). Experience with 3 dimensional tissue engineering systems.
Current research on specific progenitor cell populations for salivary gland regeneration purposes using both in vitro and in vivo models, and on a translational approach involving siRNA applications for gene therapy into radiation-damaged salivary glands. Scientific goal: to combine basic and translational research developments into new, innovative treatment options for future clinical trials.

Credentials

Faculty Appointments

Specialties

  • Dentist-General Practice

Post-doctoral Training & Residency

07/01/2016 -
Residency in Advanced Education in General Dentistry at Eastman Dental School

10/1/1995 - 09/30/1996
Internship in Dentist-Oral and Maxillofacial Surgery at Szent Istvan Hospital

10/1/1996 - 3/30/1999
Residency in Dentist-Oral and Maxillofacial Surgery at Szent Istvan Hospital

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Publications

Journal Articles

11/2015
Aure MH, Arany S, Ovitt CE. "Salivary Glands: Stem Cells, Self-duplication, or Both?" Journal of dental research.. 2015 Nov 0; 94(11):1502-7. Epub 2015 Aug 18.

6/2013
Arany S, Benoit DS, Dewhurst S, Ovitt CE. "Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo." Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 Jun 0; 21(6):1182-94. Epub 2013 Mar 19.

7/2012
Fujisawa M, Tokuda M, Morimoto-Yamashita Y, Tatsuyama S, Arany S, Sugiyama T, Kitamura C, Shibukawa Y, Torii M. "Hyperosmotic stress induces cell death in an odontoblast-lineage cell line." Journal of endodontics.. 2012 Jul 0; 38(7):931-5. Epub 2012 May 05.

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