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Daniel Croft, M.D., M.P.H.

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Phone Numbers

Appointment: (585) 276-3000

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Setting



My two main goals are to improve the health of individual patients and improve the health of populations through research on air pollution.

I treat patients with general pulmonary disease including Asthma and COPD in my outpatient clinic at the Mary Parkes Center for Asthma, Allergy & Pulmonary Care. I also have a special interest in occupational health including diseases caused by inhaled toxins. My work in the medical intensive care unit (ICU) in the University of Rochester Medical Center involves caring for critically ill patients in the hospital.

My research focuses on the health effects of air pollution, with a current focus on the contribution of air pollution to individuals suffering from respiratory viral infections. My prior work focused on the systemic effects of air pollution showing inflammation in the body. I am also actively looking for ways to protect patients from both indoor and outdoor air pollution. My research team I are placing HEPA filter units to clean the air in the homes of patients who are discharged from the hospital after COPD exacerbations. Lastly I am studying electronic nicotine delivery systems (ENDS/E-cigarettes) as part of a large research center at the University of Rochester and the Roswell Park Cancer Institute.

Our team studying air pollution at URMC includes Pulmonologists, Mark Utell, MD and Mark Frampton, MD; Environmental Epidemiologist Dave Rich (ScD); Environmental Chemist Phil Hopke (PhD); Lead Analyst Kelly Thevenet-Morrison (MS), Biostatistician Sally Thurston PhD and Carl Johnston PhD.

Professional Background

I grew up as a Hoosier, completing my undergraduate and medical school training at Indiana University. While in medical school I completed a Master's in Public Health with mentorship from Dr. Steven Jay. After completing multiple public health policy projects, I started my internal medicine training at Dartmouth Hitchcock Medical Center in New Hampshire while investigating improved health care delivery methods with health policy experts at The Dartmouth Institute.

I transitioned to Rochester in 2014 to begin my fellowship training in Pulmonary and Critical Care medicine. After meeting my aforementioned research team, I began epidemiology research on the health effects of air pollution. I will continue expanding my research from epidemiology studies to human intervention and exposure studies in our state of the art exposure chamber.

I also am invested in helping our patients quit smoking. In collaboration with the experts in public health sciences including Drs. Debbie Ossip and Scott McIntosh, I hope to improve our ability to connect our patients with smoking cessation resources. Finally I am helping in the effort to better understand electronic nicotine delivery systems through involvement in a variety of educational and formal research activities.


My main line of inquiry involves the impact of inhaled toxins on the immune response to respiratory infection.

Both the Pulmonary and Critical Care Division and the Department of Public Health Sciences at the University of Rochester Medical Center (URMC) have a long history of research in the areas of inhalation toxicology, environmental health, environmental epidemiology, and air pollution health effects. The Pulmonary Division at URMC has performed prospective human studies in one of the longest running inhalational exposure chambers in the world and has been a leader in the study of ultrafine particle inhalation, deposition, and related pulmonary and cardiovascular health effects. Our Epidemiology Division is becoming a leader in studying air pollution's effect on cardiac and pulmonary disease and has collaborated with other groups active in air pollution research around the country, including the multicenter randomized crossover trial of acute cardiovascular effects of low level ozone exposure in older adults MOSES (Multicenter Ozone Study of oldEr Subjects) trial.

My main research is on the associations between air pollution and the immune response to respiratory infections. As part of the inhalation toxicology research at URMC, my first study focused on wood smoke exposure in a group of cardiac patients. We observed that wood smoke and other particulate air pollutants were associated with an increase in levels of serum fibrinogen. A further effect modification analysis revealed that the adverse changes in fibrinogen were blunted in patients with higher levels of omega-3 fatty acids derived from fish (EPA/DHA). I am also enrolling patients with COPD exacerbations in a study of indoor HEPA filter air cleaning, with the goal of reducing COPD exacerbations. My research will range from epidemiologic assessments to panel studies of airborne exposures or pollution mitigation devices. I am also one of the investigators in the Western New York Center for Research on Flavored Tobacco Products (CRoFT), which includes research on e-cigarettes.



  • Critical Care Medicine - American Board of Internal Medicine
  • Internal Medicine - American Board of Internal Medicine
  • Pulmonary Disease - American Board of Internal Medicine


MPH | Fairbanks School of Public Health

MD | Indiana University Medical Center

Post-doctoral Training & Residency

07/01/2012 - 06/15/2014
Residency in Internal Medicine at Mary Hitchcock Memorial Hospital

06/24/2011 - 07/01/2012
Internship in Internal Medicine at Mary Hitchcock Memorial Hospital

7/1/2014 - 6/30/2017
Fellowship in Pulmonary/Critical Care at University of Rochester Medical Center

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David Bates Award for outstanding contribution to the field of Environmental, Occupational and Population Health
Sponsor: American Thoracic Society (EOPH Assembly)

Abstract scholarship
Sponsor: American Thoracic Society (EOPH Assembly)
Location: Washington, DC

Abstract scholarship
Sponsor: American Thoracic Society (EOPH Assembly)
Location: San Francisco, CA

2015 - 2016
Strong Star Certificates of Appreciation
Sponsor: University of Rochester Medical Center

Fellow Teaching Award Finalist
Sponsor: Department of Medicine
Location: University of Rochester Medical Center

Verne K. and Gladys Osborn Harvey Scholarship
Sponsor: Indiana University School of Medicine
Location: Indianapolis, IN

Honors in Biology
Sponsor: Indiana University
Location: Bloomington, IN

Guidant Life Sciences Scholarship
Sponsor: Guidant Corporation
Location: Indiana University, Bloomington

Capstone Grant for Research
Sponsor: Howard Hughes Medical Institute
Location: Bloomington, IN

Rex Grossman Award in Biology
Sponsor: Indiana University
Location: Bloomington, IN

2004 - 2006
Fernandus and Elizabeth Payne Scholarship
Sponsor: Indiana University
Location: Bloomington, IN

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Journal Articles

Croft DP, Zhang W, Lin S, Thurston SW, Hopke PK, van Wijngaarden E, Squizzato S, Masiol M, Utell MJ, Rich DQ. "Associations between Source-Specific Particulate Matter and Respiratory Infections in New York State Adults." Environmental science & technology.. 2020 Jan 21; 54(2):975-984. Epub 2019 Dec 18.

Croft DP, McGraw MD, Navarette KA, Marraffa J, Ginsberg G, Nacca NE, Bach CT, Kalininskiy A. "E-cigarette, or vaping, product use associated lung injury (EVALI): case series and diagnostic approach." The Lancet. Respiratory medicine.. 2019 Dec 0; 7(12):1017-1026. Epub 2019 Nov 08.

Hopke PK, Croft DP, Zhang W, Lin S, Masiol M, Squizzato S, Thurston SW, van Wijngaarden E, Utell MJ, Rich DQ. "Changes in the hospitalization and ED visit rates for respiratory diseases associated with source-specific PM in New York State from 2005 to 2016." Environmental research.. 2019 Nov 11; :108912. Epub 2019 Nov 11.