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Daniel Patrick Croft, M.D., M.P.H.

Pulmonary

Contact Information

Phone Numbers

Appointment: (585) 276-3000

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Biography

My two main goals are to improve the health of individual patients and improve the health of populations through research on air pollution.

I treat patients with general pulmonary disease including COPD and asthma in my outpatient clinic and also have a special interest in occupational health including diseases caused from inhaled toxins. My work in the medical intensive care unit (ICU) in the hospital involves caring for the sickest patients in the hospital, many of whom also have respiratory illnesses.

My research focuses on the health effects of air pollution, with a current focus on the contribution of air pollution to individuals suffering from respiratory viral infections. My prior work focused on the systemic effects of air pollution showing inflammation in the body. I am also actively looking for ways to protect patients from both indoor and outdoor air pollution. My research team I will soon start a trial of placing HEPA filter units to clean the air in the homes of patients who are discharged from the hospital after COPD exacerbations.

Our team studying air pollution at URMC includes Pulmonologists, Mark Utell, MD and Mark Frampton, MD; Environmental Epidemiologist Dave Rich (ScD); Environmental Chemist Phil Hopke (PhD); Lead Analyst Kelly Thevenet-Morrison (MS) and our research technician Dave Chalupa (MS).

Professional Background

I grew up as a Hoosier, completing my undergraduate and medical school training at Indiana University. While in medical school I completed a Master's in Public Health with mentorship from Steven Jay. After completing multiple public health policy projects, I started my internal medicine training at Dartmouth Hitchcock Medical Center in New Hampshire while investigating improved health care delivery methods with health policy experts at The Dartmouth Institute.

I transitioned to Rochester in 2014 to begin my fellowship training in Pulmonary and Critical Care medicine. After meeting my aforementioned research team, I began epidemiology research on the health effects of air pollution. I will continue expanding my research from epidemiology studies to human intervention and exposure studies in our state of the art exposure chamber.

I also am invested in helping our patients quit smoking. In collaboration with the experts in public health sciences including Scott McIntosh (codirector of the smoking research program at URMC), I hope to improve our ability to connect our patients with smoking cessation resources.

Research

Both the Pulmonary and Critical Care Division and the Department of Public Health Sciences at the University of Rochester Medical Center (URMC) have a long history of research in the areas of inhalation toxicology, environmental health, environmental epidemiology, and air pollution health effects. The Pulmonary Division at URMC has performed prospective human studies in one of the longest running inhalational exposure chambers in the world and has been a leader in the study of ultrafine particle inhalation, deposition, and related pulmonary and cardiovascular health effects. Our Epidemiology Division is becoming a leader in studying air pollution's effect on cardiac and pulmonary disease and has collaborated with other groups active in air pollution research around the country, including an ongoing multicenter randomized crossover trial of acute cardiovascular effects of low level ozone exposure in older adults MOSES (Multicenter Ozone Study of oldEr Subjects Trial), which is being conducted with collaborators at the University of North Carolina, the University of California San Francisco, and the Health Effects Institute.

As part of the inhalation toxicology research at URMC, my first study focused on wood smoke exposure in a group of cardiac patients. We observed that wood smoke and other particulate air pollutants were associated with an increase in levels of serum fibrinogen. A further effect modification analysis revealed that the adverse changes in fibrinogen were blunted in patients with higher levels of omega-3 fatty acids derived from fish (EPA/DHA). My current research is on the associations between air pollution and respiratory infections. I am also planning to enroll patients with COPD exacerbations in a study of indoor HEPA filter air cleaning, with the goal of reducing COPD exacerbations. My research will range from epidemiologic assessments to panel studies of airborne exposures or pollution mitigation devices.

Credentials

Faculty Appointments

Specialties

  • Internal Medicine - American Board of Internal Medicine
  • Pulmonary Disease - American Board of Internal Medicine

Post-doctoral Training & Residency

07/01/2012 - 06/15/2014
Residency in Internal Medicine at Mary Hitchcock Memorial Hospital

06/24/2011 - 07/01/2012
Internship in Internal Medicine at Mary Hitchcock Memorial Hospital

7/1/2014 - 6/30/2017
Fellowship in Pulmonary/Critical Care at University of Rochester Medical Center

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Awards

2017
Abstract scholarship
Sponsor: American Thoracic Society (EOPH)
Location: Washington, DC

2016
Abstract scholarship
Sponsor: American Thoracic Society (EOPH)
Location: San Francisco, CA

2015 - 2016
Strong Star Certificates of Appreciation
Sponsor: University of Rochester Medical Center

2015
Fellow Teaching Award Finalist
Sponsor: Department of Medicine
Location: University of Rochester Medical Center

2010
Verne K. and Gladys Osborn Harvey Scholarship
Sponsor: Indiana University School of Medicine
Location: Indianapolis, IN

2006
Honors in Biology
Sponsor: Indiana University
Location: Bloomington, IN

2006
Guidant Life Sciences Scholarship
Sponsor: Guidant Corporation
Location: Indiana University, Bloomington

2005
Capstone Grant for Research
Sponsor: Howard Hughes Medical Institute
Location: Bloomington, IN

2005
Rex Grossman Award in Biology
Sponsor: Indiana University
Location: Bloomington, IN

2004 - 2006
Fernandus and Elizabeth Payne Scholarship
Sponsor: Indiana University
Location: Bloomington, IN

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Publications

Journal Articles

8/2017
Lachant DJ, Croft DP, McGrane Minton H, Prasad P, Kottmann RM. "Nasopharyngeal viral PCR in immunosuppressed patients and its association with virus detection in bronchoalveolar lavage by PCR." Respirology : official journal of the Asian Pacific Society of Respirology.. 2017 Aug 0; 22(6):1205-1211. Epub 2017 Apr 05.

2017
Croft DP, Cameron SJ, Morrell CN, Lowenstein CJ, Ling F, Zareba W, Hopke PK, Utell MJ, Thurston SW, Thevenet-Morrison K, Evans KA, Chalupa D, Rich DQ. "Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients." Environmental research.. 2017 154:352-361. Epub 2017 Feb 04.

2015
Croft DP, Philippo SM, Prasad P. "A case of Lemierre's syndrome with septic shock and complicated parapneumonic effusions requiring intrapleural fibrinolysis." Respiratory medicine case reports. 2015 16:86-8. Epub 2015 Aug 24.

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