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Manoj J. Mammen, M.D.

Manoj J. Mammen, M.D.

he/him/his

Pulmonary & Critical Care Medicine , Internal Medicine

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
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About Me

As a clinician, educator, and researcher in pulmonary and critical care medicine, I strive to improve the health of individuals with respiratory diseases significantly. With nearly 12 years of experience as an associate professor of medicine at the University of Buffalo and now as a faculty member a...
As a clinician, educator, and researcher in pulmonary and critical care medicine, I strive to improve the health of individuals with respiratory diseases significantly. With nearly 12 years of experience as an associate professor of medicine at the University of Buffalo and now as a faculty member at the University of Rochester, I am dedicated to fostering excellence in education. My role involves teaching medical students, residents, and fellows, ensuring they acquire the necessary skills and knowledge to provide high-quality care to patients with pulmonary diseases and critical illnesses.

In my clinical practice, primarily at Strong Memorial Hospital, I provide comprehensive care to patients with various pulmonary conditions, including ARDS, asthma, COPD, interstitial lung disease, pleural disease, pulmonary hypertension, and lung cancer. Additionally, I am actively involved in the Mary Parkes Asthma Center, evaluating patients in the outpatient setting who present with pulmonary disorders. Collaborating with a dedicated team of healthcare professionals, I strive to deliver exceptional care across multiple practice locations.

Beyond my clinical, research, and educational activities, I am dedicated to leadership and service in the field. As an executive board member of the New York State Thoracic Society (NYSTS), I have held positions such as program chair of the annual conference, secretary, treasurer, and currently serve as the vice president. Additionally, I am a chapter council representative to the ATS and have served as the president of the ATS's Council of Chapters Committee. These roles allow me to contribute to the advancement of the field, impact global health, and transform patient care.

In summary, my passion lies in advancing the field of pulmonary and critical care medicine through clinical practice, research, education, leadership, and service. My focus on computational approaches, multi-omic data analysis, and guideline development allows me to make significant contributions to understanding COPD pathogenesis, identifying therapeutic targets, and improving patient outcomes. I strive to empower the next generation of healthcare professionals to provide exceptional care through my dedication to education and professional development.

Professional Background

I received my undergraduate and medical school training at Rutgers University and New Jersey Medical school. I trained at Baylor College of Medicine, in Houston, TX during my Internal Medicine residency and Pulmonary//Critical Care fellowship. Subsequently my first faculty position after training wa...
I received my undergraduate and medical school training at Rutgers University and New Jersey Medical school. I trained at Baylor College of Medicine, in Houston, TX during my Internal Medicine residency and Pulmonary//Critical Care fellowship. Subsequently my first faculty position after training was at the University of Buffalo Pulmonary/Critical Care division. I worked as pulmonary and critical care provider at the Buffalo General Medical Center and a pulmonary provider at Roswell Park Comprehensive Cancer Center for 12 years prior to being recruited the University of Rochester Medical Center's Pulmonary and Critical Care division.
I see patients as a pulmonary provider in the Mary Parkes Asthma Center and the inpatient pulmonary consult service at Strong Memorial Hospital. I also see patients as a critical care provider in the medical intensive care units at the Strong Memorial Hospital.

Faculty Appointments

Associate Professor - Department of Medicine, Pulmonary Diseases and Critical Care (SMD)

Credentials

Residency & Fellowship

Fellowship, National Cancer Institute/National Institute of Health. 2016 - 2018

Fellowship, Buffalo General Hospital-Kaleida Health. 2014 - 2016

Fellowship, Pulmonary and Critical Care Medicine, Baylor College of Medicine-Pulmonary/Critical Care Fellowship. 2007 - 2010

Residency, Internal Medicine, Baylor College of Medicine. 2005 - 2007

Internship, Internal Medicine, Baylor College of Medicine. 2004 - 2005

Education

MS | SUNY at Buffalo-School of Medicine & Biomedical Sciences (USA). Medical Genetics, Clinical Genetics (M.D.). 2016

MD | Rutgers New Jersey Medical School. 2004

Research

Throughout my research career, I have been engaged in a diverse range of studies and clinical trials aimed at advancing our understanding of various diseases and enhancing patient outcomes. These endeavors have been supported by prestigious organizations, including the National Institutes of Health ...
Throughout my research career, I have been engaged in a diverse range of studies and clinical trials aimed at advancing our understanding of various diseases and enhancing patient outcomes. These endeavors have been supported by prestigious organizations, including the National Institutes of Health (NIH), the National Center for Advancing Translational Sciences (NCATS), and the Department of Defense (DoD) . The recognition and funding provided by these esteemed agencies have empowered me to conduct innovative investigations and make significant contributions to the field.

One of the main focuses of my research has been chronic obstructive pulmonary disease (COPD), a complex respiratory condition associated with significant morbidity and mortality. Collaborating with renowned experts, I have explored the intricate mechanisms driving COPD pathogenesis, particularly the network biology of pathogen-host interactions during disease exacerbations. As a co-investigator, I have played a crucial role in analyzing transcriptome and microbiome data obtained from clinical samples. This research, funded by esteemed organizations, aims to uncover novel insights into COPD exacerbations and identify potential therapeutic targets.

Additionally, I have actively contributed to the study of COVID-19, a global pandemic that has posed significant challenges to healthcare systems worldwide. As a site principal investigator, I have made substantial contributions to two prominent clinical trials investigating potential treatments for COVID-19. These trials, funded by the NIH and NCATS/NIH, are evaluating the efficacy and safety of immune-based interventions for COVID-19. My responsibilities have included overseeing trial selection, site activation, and study execution, with a focus on maximizing enrollment and data quality. The outcomes of these trials have the potential to shape treatment strategies and improve patient outcomes.

Furthermore, I have explored the connection between the airway microbiome and lung cancer in a COPD cohort, offering valuable insights into the complex relationships between these conditions.

In my research, I have also focused on investigating the role of galectin-3 in asthma. Galectin-3 is a protein involved in inflammation and tissue remodeling. By studying its implications in asthma, I aim to gain insights into the underlying mechanisms of the disease and potentially identify novel therapeutic targets. This research contributes to our understanding of asthma pathogenesis and may lead to the development of more effective treatment strategies for individuals with this chronic respiratory condition.

In addition to translational and clinical research, I actively engage in developing and implementing clinical practice guidelines, utilizing the GRADE methodology, and advancing evidence-based medicine. As a member of the American Thoracic Society (ATS), I have played a critical role in creating guidelines for the treatment of COPD and interstitial lung disease. I additionally co-authored surviving sepsis guidelines for COVID-19 management during the COVID-19 pandemic. These guidelines, based on rigorous evaluation of the available evidence, optimize patient care and ensure standardized approaches to management.

In summary, my research journey is dedicated to unraveling the complexities of respiratory diseases, identifying therapeutic targets, and making meaningful contributions to patient care. Through collaborations, funding support, and guideline development, I aim to transform patient care, improve outcomes, and shape the future of pulmonary medicine.

Publications

Journal Articles

Gabapentin to treat acute alcohol withdrawal in hospitalized patients: A systematic review and meta-analysis.

Mattle AG, McGrath P, Sanu A, Kunadharaju R, Kersten B, Zammit K, Mammen MJ

Drug and alcohol dependence.. 2022 October 21241 :109671. Epub 10/21/2022.

Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized with COVID-19: A Blinded Randomized Placebo-Controlled Trial.

Self WH, Wheeler AP, Stewart TG, Schrager H, Mallada J, Thomas CB, Cataldo VD, O'Neal HR, Shapiro NI, Higgins C, Ginde AA, Chauhan L, Johnson NJ, Henning DJ, Jaiswal SJ, Mammen MJ, Harris ES, Pannu SR, Laguio-Vila M, El Atrouni W, de Wit M, Hoda D, Cohn CS, McWilliams C, Shanholtz C, Jones AE, Raval JS, Mucha S, Ipe TS, Qiao X, Schrantz SJ, Shenoy A, Fremont RD, Brady EJ, Carnahan RH, Chappell JD, Crowe JE, Denison MR, Gilchuk P, Stevens LJ, Sutton RE, Thomsen I, Yoder SM, Bistran-Hall AJ, Casey JD, Lindsell CJ, Wang L, Pulley JM, Rhoads JP, Bernard GR, Rice TW,

Chest.. 2022 June 30 Epub 06/30/2022.

Venous and arterial thrombosis in COVID-19: An updated narrative review.

Duhailib ZA, Oczkowski S, Polok K, Fronczek J, Szczeklik W, Piticaru J, Mammen MJ, Alshamsi F, Eikelboom J, Belley-Cote E, Alhazzani W

Journal of infection and public health.. 2022 May 1415 (6):689-702. Epub 05/14/2022.

Pirfenidone in Progressive Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.

Ghazipura M, Mammen MJ, Bissell BD, Macrea M, Herman DD, Hon SM, Kheir F, Khor YH, Knight SL, Raghu G, Wilson KC, Hossain T

Annals of the American Thoracic Society.. 2022 May 2 Epub 05/02/2022.

Nintedanib in Progressive Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.

Ghazipura M, Mammen MJ, Herman DD, Hon SM, Bissell BD, Macrea M, Kheir F, Khor YH, Knight SL, Raghu G, Wilson KC, Hossain T

Annals of the American Thoracic Society.. 2022 May 2 Epub 05/02/2022.

Transbronchial Lung Cryobiopsy in Patients with Interstitial Lung Disease: A Systematic Review.

Kheir F, Uribe Becerra JP, Bissell BD, Ghazipura M, Herman DD, Hon SM, Hossain T, Khor YH, Knight SL, Kreuter M, Macrea M, Mammen MJ, Martinez FJ, Poletti V, Troy L, Raghu G, Wilson KC

Annals of the American Thoracic Society.. 2022 May 2 Epub 05/02/2022.

Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.

Raghu G, Remy-Jardin M, Richeldi L, Thomson CC, Inoue Y, Johkoh T, Kreuter M, Lynch DA, Maher TM, Martinez FJ, Molina-Molina M, Myers JL, Nicholson AG, Ryerson CJ, Strek ME, Troy LK, Wijsenbeek M, Mammen MJ, Hossain T, Bissell BD, Herman DD, Hon SM, Kheir F, Khor YH, Macrea M, Antoniou KM, Bouros D, Buendia-Roldan I, Caro F, Crestani B, Ho L, Morisset J, Olson AL, Podolanczuk A, Poletti V, Selman M, Ewing T, Jones S, Knight SL, Ghazipura M, Wilson KC

American journal of respiratory and critical care medicine.. 2022 May 1205 (9):e18-e47. Epub 1900 01 01.

Proteomic Network Analysis of Bronchoalveolar Lavage Fluid in Ex-Smokers to Discover Implicated Protein Targets and Novel Drug Treatments for Chronic Obstructive Pulmonary Disease.

Mammen MJ, Tu C, Morris MC, Richman S, Mangione W, Falls Z, Qu J, Broderick G, Sethi S, Samudrala R

Pharmaceuticals.. 2022 May 115 (5)Epub 05/01/2022.

Antacid Medication and Antireflux Surgery in Patients with Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.

Khor YH, Bissell B, Ghazipura M, Herman D, Hon SM, Hossain T, Kheir F, Knight SL, Kreuter M, Macrea M, J Mammen M, Molina-Molina M, Selman M, Wijsenbeek M, Raghu G, Wilson KC

Annals of the American Thoracic Society.. 2022 May 19 (5):833-844. Epub 1900 01 01.

Leukotriene inhibitors with dexamethasone show promise in the prevention of death in COVID-19 patients with low oxygen saturations.

Elkin PL, Resendez S, Mullin S, Troen BR, Mammen MJ, Chang S, Franklin G, McCray W, Brown SH

Journal of clinical and translational science.. 2022 6 (1):e74. Epub 05/16/2022.

Types of garlic and their anticancer and antioxidant activity: a review of the epidemiologic and experimental evidence.

Farhat Z, Hershberger PA, Freudenheim JL, Mammen MJ, Hageman Blair R, Aga DS, Mu L

European journal of nutrition.. 2021 October 60 (7):3585-3609. Epub 02/04/2021.

Use of a Genomic Classifier in Patients with Interstitial Lung Disease: A Systematic Review.

Kheir F, Uribe Becerra JP, Bissell B, Ghazipura M, Herman D, Hon SM, Hossain T, Khor YH, Knight SL, Kreuter M, Macrea M, Mammen MJ, Martinez FJ, Poletti V, Troy L, Raghu G, Wilson KC

Annals of the American Thoracic Society.. 2021 June 2 Epub 06/02/2021.

Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis.

Chaudhuri D, Sasaki K, Karkar A, Sharif S, Lewis K, Mammen MJ, Alexander P, Ye Z, Lozano LEC, Munch MW, Perner A, Du B, Mbuagbaw L, Alhazzani W, Pastores SM, Marshall J, Lamontagne F, Annane D, Meduri GU, Rochwerg B

Intensive care medicine.. 2021 May 47 (5):521-537. Epub 04/19/2021.

Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults.

Self WH, Stewart TG, Wheeler AP, El Atrouni W, Bistran-Hall AJ, Casey JD, Cataldo VD, Chappell JD, Cohn CS, Collins JB, Denison MR, de Wit M, Dixon SL, Duggal A, Edwards TL, Fontaine MJ, Ginde AA, Harkins MS, Harrington T, Harris ES, Hoda D, Ipe TS, Jaiswal SJ, Johnson NJ, Jones AE, Laguio-Vila M, Lindsell CJ, Mallada J, Mammen MJ, Metcalf RA, Middleton EA, Mucha S, O'Neal HR, Pannu SR, Pulley JM, Qiao X, Raval JS, Rhoads JP, Schrager H, Shanholtz C, Shapiro NI, Schrantz SJ, Thomsen I, Vermillion KK, Bernard GR, Rice TW,

Trials.. 2021 March 2022 (1):221. Epub 03/20/2021.

Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults.

Self WH, Stewart TG, Wheeler AP, El Atrouni W, Bistran-Hall AJ, Casey JD, Cataldo VD, Chappell JD, Cohn CS, Collins JB, Denison MR, de Wit M, Dixon SL, Duggal A, Edwards TL, Fontaine MJ, Ginde AA, Harkins MS, Harrington T, Harris ES, Hoda D, Ipe TS, Jaiswal SJ, Johnson NJ, Jones AE, Laguio-Vila M, Lindsell CJ, Mallada J, Mammen MJ, Metcalf RA, Middleton EA, Mucha S, O'Neal HR, Pannu SR, Pulley JM, Qiao X, Raval JS, Rhoads JP, Schrager H, Shanholtz C, Shapiro NI, Schrantz SJ, Thomsen I, Vermillion KK, Bernard GR, Rice TW

Research square.. 2021 March 2 Epub 03/02/2021.

Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update.

Alhazzani W, Evans L, Alshamsi F, Møller MH, Ostermann M, Prescott HC, Arabi YM, Loeb M, Ng Gong M, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Machado F, Wunsch H, Crowther M, Cecconi M, Koh Y, Burry L, Chertow DS, Szczeklik W, Belley-Cote E, Greco M, Bala M, Zarychanski R, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Nainan Myatra S, Arrington A, Kleinpell R, Citerio G, Lewis K, Bridges E, Memish ZA, Hammond N, Hayden FG, Alshahrani M, Al Duhailib Z, Martin GS, Kaplan LJ, Coopersmith CM, Antonelli M, Rhodes A

Critical care medicine.. 2021 March 149 (3):e219-e234. Epub 1900 01 01.

Reply to Vozoris: Opioids for Dyspnea in Chronic Obstructive Pulmonary Disease: Short on the Details.

Mammen MJ, Charbek E, Alexander PE, Nici L, Aaron SD

American journal of respiratory and critical care medicine.. 2021 January 15203 (2):267-269. Epub 1900 01 01.

Summary for Clinicians: Clinical Practice Guideline on Pharmacologic Management of Chronic Obstructive Pulmonary Disease.

Gartman EJ, Mulpuru SS, Mammen MJ, Alexander PE, Nici L, Aaron SD, Ruminjo JK, Thomson CC

Annals of the American Thoracic Society.. 2021 January 18 (1):11-16. Epub 1900 01 01.

Developing trustworthy recommendations as part of an urgent response (1-2 weeks): a GRADE concept paper.

Akl EA, Morgan RL, Rooney AA, Beverly B, Katikireddi SV, Agarwal A, Alper BS, Alva-Diaz C, Amato L, Ansari MT, Brozek J, Chu DK, Dahm P, Darzi AJ, Falavigna M, Gartlehner G, Pardo-Hernandez H, King V, Klugarová J, Langendam MWM, Lockwood C, Mammen M, Mathioudakis AG, McCaul M, Meerpohl JJ, Minozzi S, Mustafa RA, Nonino F, Piggott T, Qaseem A, Riva J, Rodin R, Sekercioglu N, Skoetz N, Traversy G, Thayer K, Schünemann H

Journal of clinical epidemiology.. 2021 January 129 :1-11. Epub 09/30/2020.

IL-17 Is a Key Regulator of Mucin-Galectin-3 Interactions in Asthma.

Mammen MJ, Ali J, Aurora A, Sharma UC, Aalinkeel R, Mahajan SD, Sands M, Schwartz SA

International journal of cell biology.. 2021 2021 :9997625. Epub 06/09/2021.

Triple Therapy versus Dual or Monotherapy with Long-Acting Bronchodilators for Chronic Obstructive Pulmonary Disease. A Systematic Review and Meta-analysis.

Mammen MJ, Lloyd DR, Kumar S, Ahmed AS, Pai V, Kunadharaju R, Gupta S, Nici L, Aaron SD, Alexander PE

Annals of the American Thoracic Society.. 2020 October 17 (10):1308-1318. Epub 1900 01 01.

Dual LABA/LAMA Therapy versus LABA or LAMA Monotherapy for Chronic Obstructive Pulmonary Disease. A Systematic Review and Meta-analysis in Support of the American Thoracic Society Clinical Practice Guideline.

Mammen MJ, Pai V, Aaron SD, Nici L, Alhazzani W, Alexander PE

Annals of the American Thoracic Society.. 2020 September 17 (9):1133-1143. Epub 1900 01 01.

Vertical transmission risk of SARS-CoV-2 infection in the third trimester: a systematic scoping review.

Thomas P, Alexander PE, Ahmed U, Elderhorst E, El-Khechen H, Mammen MJ, Debono VB, Aponte Torres Z, Aryal K, Brocard E, Sagastuy B, Alhazzani W

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.. 2020 July 1 :1-8. Epub 07/01/2020.

COVID-19 coronavirus research has overall low methodological quality thus far: case in point for chloroquine/hydroxychloroquine.

Alexander PE, Debono VB, Mammen MJ, Iorio A, Aryal K, Deng D, Brocard E, Alhazzani W

Journal of clinical epidemiology.. 2020 July 123 :120-126. Epub 04/21/2020.

Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19).

Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Aboodi M, Wunsch H, Cecconi M, Koh Y, Chertow DS, Maitland K, Alshamsi F, Belley-Cote E, Greco M, Laundy M, Morgan JS, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Alexander PE, Arrington A, Centofanti JE, Citerio G, Baw B, Memish ZA, Hammond N, Hayden FG, Evans L, Rhodes A

Critical care medicine.. 2020 June 48 (6):e440-e469. Epub 1900 01 01.

Oral-lung microbiome interactions in lung diseases.

Mammen MJ, Scannapieco FA, Sethi S

Periodontology 2000.. 2020 June 83 (1):234-241. Epub 1900 01 01.

Pharmacologic Management of Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline.

Nici L, Mammen MJ, Charbek E, Alexander PE, Au DH, Boyd CM, Criner GJ, Donaldson GC, Dreher M, Fan VS, Gershon AS, Han MK, Krishnan JA, Martinez FJ, Meek PM, Morgan M, Polkey MI, Puhan MA, Sadatsafavi M, Sin DD, Washko GR, Wedzicha JA, Aaron SD

American journal of respiratory and critical care medicine.. 2020 May 1201 (9):e56-e69. Epub 1900 01 01.

Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19).

Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Aboodi M, Wunsch H, Cecconi M, Koh Y, Chertow DS, Maitland K, Alshamsi F, Belley-Cote E, Greco M, Laundy M, Morgan JS, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Alexander PE, Arrington A, Centofanti JE, Citerio G, Baw B, Memish ZA, Hammond N, Hayden FG, Evans L, Rhodes A

Intensive care medicine.. 2020 May 46 (5):854-887. Epub 03/28/2020.

Corticosteroids for patients with acute respiratory distress syndrome: a systematic review and meta-analysis of randomized trials.

Mammen MJ, Aryal K, Alhazzani W, Alexander PE

Polish archives of internal medicine.. 2020 April 30130 (4):276-286. Epub 03/18/2020.

Interferon beta-1a for patients with moderate to severe acute respiratory distress syndrome: a systematic review and meta-analysis of randomized trials.

Mammen MJ, Aryal K, Alhazzani W, Deng DY, Alexander PE

Polish archives of internal medicine.. 2020 April 30130 (4):287-296. Epub 04/03/2020.

Prediction model development of women's daily asthma control using fitness tracker sleep disruption.

Castner J, Jungquist CR, Mammen MJ, Pender JJ, Licata O, Sethi S

Heart & lung : the journal of critical care.. 2020 49 (5):548-555. Epub 02/20/2020.

Validation of fitness tracker for sleep measures in women with asthma.

Castner J, Mammen MJ, Jungquist CR, Licata O, Pender JJ, Wilding GE, Sethi S

The Journal of asthma : official journal of the Association for the Care of Asthma.. 2019 July 56 (7):719-730. Epub 08/24/2018.

Role of Galectin-3 in the pathophysiology underlying allergic lung inflammation in a tissue inhibitor of metalloproteinases 1 knockout model of murine asthma.

Mammen MJ, Sands MF, Abou-Jaoude E, Aalinkeel R, Reynolds JL, Parikh NU, Sharma U, Schwartz SA, Mahajan SD

Immunology.. 2018 March 153 (3):387-396. Epub 11/07/2017.

Galectin-1 Reduces Neuroinflammation via Modulation of Nitric Oxide-Arginase Signaling in HIV-1 Transfected Microglia: a Gold Nanoparticle-Galectin-1 "Nanoplex" a Possible Neurotherapeutic?

Aalinkeel R, Mangum CS, Abou-Jaoude E, Reynolds JL, Liu M, Sundquist K, Parikh NU, Chaves LD, Mammen MJ, Schwartz SA, Mahajan SD

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.. 2017 March 12 (1):133-151. Epub 12/27/2016.

COPD and the microbiome.

Mammen MJ, Sethi S

Respirology : official journal of the Asian Pacific Society of Respirology.. 2016 May 21 (4):590-9. Epub 01/27/2016.

Galectin-1 suppresses methamphetamine induced neuroinflammation in human brain microvascular endothelial cells: Neuroprotective role in maintaining blood brain barrier integrity.

Parikh NU, Aalinkeel R, Reynolds JL, Nair BB, Sykes DE, Mammen MJ, Schwartz SA, Mahajan SD

Brain research.. 2015 October 221624 :175-187. Epub 07/30/2015.

Nanotherapeutic approach for opiate addiction using DARPP-32 gene silencing in an animal model of opiate addiction.

Ignatowski TA, Aalinkeel R, Reynolds JL, Nair BB, Sykes DE, Gleason CP, Law WC, Mammen MJ, Prasad PN, Schwartz SA, Mahajan SD

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.. 2015 March 10 (1):136-52. Epub 01/22/2015.

Impaired Innate COPD Alveolar Macrophage Responses and Toll-Like Receptor-9 Polymorphisms.

Berenson CS, Kruzel RL, Wrona CT, Mammen MJ, Sethi S

PloS one.. 2015 10 (9):e0134209. Epub 09/11/2015.

Large-scale, ion-current-based proteomics investigation of bronchoalveolar lavage fluid in chronic obstructive pulmonary disease patients.

Tu C, Mammen MJ, Li J, Shen X, Jiang X, Hu Q, Wang J, Sethi S, Qu J

Journal of proteome research.. 2014 February 713 (2):627-639. Epub 12/02/2013.

Morphine and galectin-1 modulate HIV-1 infection of human monocyte-derived macrophages.

Reynolds JL, Law WC, Mahajan SD, Aalinkeel R, Nair B, Sykes DE, Mammen MJ, Yong KT, Hui R, Prasad PN, Schwartz SA

The Journal of immunology : official journal of the American Association of Immunologists.. 2012 April 15188 (8):3757-65. Epub 03/19/2012.

Macrolide therapy for the prevention of acute exacerbations in chronic obstructive pulmonary disease.

Mammen MJ, Sethi S

Polskie Archiwum Medycyny Wewn?trznej.. 2012 122 (1-2):54-9. Epub 1900 01 01.

Cross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokers.

Hesselbacher SE, Ross R, Schabath MB, Smith EO, Perusich S, Barrow N, Smithwick P, Mammen MJ, Coxson H, Krowchuk N, Corry DB, Kheradmand F

International journal of environmental research and public health.. 2011 May 8 (5):1324-40. Epub 04/29/2011.

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