I am thrilled to enhance the already superb breast team at Pluta Breast Center/Wilmot Cancer Institute. We aim to provide true multi-disciplinary care, meaning patients will see multiple providers in one encounter, who then present the treatment plan to the patient as a team. This type of care ensures that patients receive cutting edge treatments.

Area of Expertise
• Breast Cancer
• Benign Breast Disease
• Breast and Axillary Surgery

Area of Special Interest
• Surgery after Neoadjuvant Systemic Therapy
• Patients with an Inherited Risk of Developing Breast Cancer

I chose Breast Surgery as my specialty because breast cancer patients are inspiring – they are beaming with hope for themselves, as well as for other breast cancer patients who may come after them. This means that patients join clinical trials, for example, and try to make breast cancer care better for the world. It’s extremely rewarding to care for such engaged, hopeful patients.

My approach to patient care is based on shared decision-making, meaning I do my best to explain everything in a way each patient can understand and be wholly involved in their treatment decisions.

I was born and raised in Syracuse NY, and my entire family still resides there. In addition, my family traditionally spent every holiday season visiting my godparents in Henrietta! I am truly excited for this homecoming, and to serve the community that helped make me who I am today.

Certified Specialties

Surgery (General Surgery) - American Board of Surgery

Faculty Appointments

Associate Professor - Department of Surgery, Oncology (SMD)

Pluta Professor in Breast Care - Department of Surgery (SMD)

Associate Professor - Cancer Center - Joint

Credentials

Residency & Fellowship

Fellowship, Surgery, Breast, University of Texas MD Anderson Cancer Center. 2016 - 2017

Internship, Surgery (General Surgery), University of California San Diego-General Surgery. 2008 - 2009

Residency, Internship/Residency, University of California San Diego-General Surgery. 2008 - 2016

Education

MD | Case Western Reserve University. 2008

Awards

Early Career Women Faculty Leadership Development Seminar, Association of American Medical Colleges, Applied and accepted for le. 2021

Best Manuscript Award, Association of Women Surgeons. 2018

Conquer Cancer Merit Award American Society of Clinical Oncology (ASCO) Research, outstanding poster by a trainee. 2017

Corynee S. Uhl Award, MD Anderson Cancer Center, For excellence and compassionate breast cancer patient care. 2017

American College of Surgeons Leadership and Advocacy Summit Resident and Associate Society of ACS, Travel Grant to attend the Su. 2016

Jeopardy Contestant and Winner, San Diego Chapter of the American College of Surgeons (ACS). 2015

Outstanding Clinical/Outcomes Research Award, Surgery Research Showcase, UCSD. 2014

Grant award to fund "Breaking the Glass Ceiling: A Dinner Symposium"Chancellor's Committee on the Status of Women, UCSD, Co-chai. 2012

Award for Research Excellence at Lepow Day, AOA, Case Western Reserve University. 2006

Crile Fellowship, Case Western Reserve University Research in pediatric pulmonology at Rainbow Babies and Children's Hospital,. 2005

Training Grant Cystic Fibrosis Foundation, Research in pediatric pulmonology at Rainbow Babies and Children's Hospital. 2005

Josephine E. and Kenneth M. Schreck, MD Family Endowment Fund Annual Scholarship Award, Case Western Reserve University, School. 2004 - 2008

Research

Clinical Trials

OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy

Lead Researcher: Anna Weiss

The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembr...

Ratings & Comments

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Ratings

Care provider's discussion of any proposed treatment (options, risks, benefits, etc.)

4.9

Likelihood of recommending this care provider to others

4.9

Explanations the care provider gave you about your problem or condition

4.9

Care provider's efforts to include you in decisions about your care

4.9

Concern the care provider showed for your questions or worries

4.9

Patient Comments

5.0

Dr. Weiss is a highly skilled surgeon who is both kind and compassionate. I give her my highest recommendation to anyone in need of her care!

Sep 14, 2025

4.8

Dr Weiss was very thorough about ALL the possibilities. I was fore-warned and expected that approach, however, a more timid person might have been over-whelmed. I have no doubt she is an excellent & skilled surgeon.

Jul 14, 2025

5.0

Dr. Weiss provided insight from her experience and research. Explained everything thoroughly.

Jun 20, 2025

5.0

Good experience

Jun 14, 2025

5.0

I was very anxious. She was kind, professional, and reassuring.

May 25, 2025

5.0

Dr Weiss and I got off to a bit of a rocky start, but it ended on very sound footing. She wrote down study after study that explains the changes in treatment for early stage breast cancer. She was thorough, listened, and was personable. I had already met with my previous breast cancer surgeon, who I love and trust, but will definitely go with Dr Weiss because she is more up to date and because Pluta provides comprehensive care. I'm delighted by the new offerings since my previous breast cancer diagnosis in 2013. I feel confident going forward with our plan.

Feb 10, 2025

4.8

I was comfortable with both surgeons before surgery. They both helped to get me to that surgery's

Feb 04, 2025

5.0

Helpful and kind care from everyone I met from my first telephone call

Sep 28, 2024

5.0

I was very impressed about her knowledge and love she showed.

Aug 11, 2024

5.0

Dr. Weiss asked for my input on my condition then proceeded to use drawings with her explanation of why additional surgery was necessary.

Jul 05, 2024

5.0

Drs. Weiss and Huston were very attentive, I appreciated their listening and fully explaining my diagnosis and treatment options. I liked seeing both of them together to review my treatment.

Nov 12, 2023