Akinyemi O Kennedy SD McSally JP Mathews DH
NMR and molecular dynamics demonstrate the RNA internal loop GAGU is dynamic and adjacent base pairs determine conformational preference. ; Biophysical journal. 2025 Nov 18.
Grove AK Das A Wakabayashi H Ivanov AV Ermolenko DN
An smFRET assay to probe the impact of antibiotics on intersubunit rotation in eukaryotic ribosomes. ; Methods in enzymology; Vol 725, pp. 77-103. 2025 Nov 11.
Park BJ Hua S Casler KD Cefaloni E Ayers MC Lake RF Murphy KE Vertino PM O'Connell MR Murphy PJ
CUT&Tag overcomes biases of ChIP and establishes chromatin patterns for repetitive genomic loci. ; iScience; Vol 28(11), pp. 113757. 2025 Oct 13.
Piraino LR Chen CY Mereness JA Dunman PM Ovitt CE Benoit DSW DeLouise LA
Salivary gland tissue chip screening identifies candidate radioprotective drugs. ; Communications medicine; Vol 5(1), pp. 420. 2025 Oct 09.
Gu N Baliga UK Porter JJ Lueck JD Dean DA
Subnuclear organization and mislocalization of plasmids reduce transgene expression. ; Molecular therapy. Nucleic acids; Vol 36(4), pp. 102730. 2025 Oct 09.
Lin B Woo S Philbrick A Bacsa J Laskey E Mehra N Gondil VS Mei JA Jones G Pavelka MS Dziejman M Shutter DA Melander C Perritt AM Jakober R Shen Y Chang W-C Quave CL Dunman PM Luedemann G
Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments. ; mSphere. 2025 Sep 23.
Sipple MT Hamazaki S Todorow V Cisco LA Lupia KM Heil CS Meinke P Thornton CA Lueck JD
Elimination of myotonia improves myopathy in a muscleblind knockout model of myotonic dystrophy. ; bioRxiv : the preprint server for biology. 2025 Sep 21.
Pan Y Kierzek E Kierzek R Mathews DH Yu YT
A Ψ-Ψ codon-anticodon pairing in nonsense suppression and translational recoding. ; Nature chemical biology. 2025 Sep 12.
Porter JJ Ko W Sorensen EG Cheung Z Couch T Gabell JT Shwe V Hyatt J Licata JB Peterson LK Dean DA Lueck JD
Anticodon Edited Transfer RNAs (ACE-tRNAs) Encoded as Therapeutic Nonviral Minimal DNA Vectors. ; bioRxiv : the preprint server for biology. 2025 Sep 06.
Heatwole CR Luebbe E Hamel J Mongiovi PC Ciafaloni E Dilek N Martens WB Weber DR Rashid H Allen McKeown J Smith CH Howell S Rosero SZ Eichinger K Baker LS Dekdebrun JM Hilbert JE Varma A Thornton CA McDermott MP Moxley RT
Study of Testosterone and Recombinant Human Growth Hormone in Facioscapulohumeral Muscular Dystrophy. ; Neurology. Genetics; Vol 11(5), pp. e200292. 2025 Aug 27.
Cognetti JS Miller BL
Real-Time, Continuous Monitoring of Tissue Chips as an Emerging Opportunity for Biosensing. ; Sensors (Basel, Switzerland); Vol 25(16). 2025 Aug 19.
McGrath KE Olsen JL Koniski AD Murphy KE Getman M An HH Schulz VP Kim AR Zhang B Carlson TL Papoin J Blanc L Kingsley PD Westhoff CM Gallagher PG Chou ST Steiner LA Palis J
BMI1 regulates human erythroid self-renewal through both gene repression and gene activation. ; Nature communications; Vol 16(1), pp. 7619. 2025 Aug 15.
Baliga UK Yang L Ivanov A Schwartz JL Jiang F Khor ES Das D Wainwright L Yao P
Translational Control in Cardiac Pathophysiology and Therapeutic Development: When mRNA Meets the Heart. ; International journal of molecular sciences; Vol 26(16). 2025 Aug 14.
Luchsinger C Dai AZ Yalamanchili H Balakrishnan A Huang KL Bertelli C Cui B Lorenzo-Redondo R Wagner EJ Diaz-Griffero F
HIV-1 Infection Regulates Gene Expression by Altering Alternative Polyadenylation Through CPSF6 and CPSF5 Delocalization. ; bioRxiv : the preprint server for biology. 2025 Aug 07.
Wakabayashi H Zhu M Grayhack EJ Mathews DH Ermolenko DN
40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion. ; RNA (New York, N.Y.). 2025 Jul 31.
Mittal A Mathews DH
AlignmentFold and AlignmentPartition: Improving the align-then-fold approach for RNA secondary structure prediction. ; bioRxiv : the preprint server for biology. 2025 Jul 28.
Murphy K Getman M Lv X Murphy Z Abid D Rahman N Bulger M Steiner L
Histone H4 lysine 20 methylation marks genes dynamically regulated during erythroid maturation. ; Epigenetics & chromatin; Vol 18(1), pp. 48. 2025 Jul 26.
Butt JN Steiner DJ Bryan MR Mann KE Miller BL
A Dual-Readout Photonic Sensor for Simultaneous Measurement of Enzyme Activity and Concentration. ; ACS sensors. 2025 Jul 24.
Ko W Porter JJ Spelier S Sorensen EG Bhatt P Gabell JT van der Windt I Couch T Coote K Mense M Beekman JM Lueck JD
ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosis. ; Nucleic acids research; Vol 53(13). 2025 Jul 08.
Kurosaki T Cho H Abshire ET Pröschel C Mitsutomi S Sato H Simko EAJ Fraser CS Sakano H Maquat LE
FMRP drives mRNP targets into translationally silenced complexes. ; Molecular cell. 2025 Jul 08.
Klose AM Katz JD Boni R Nelson D Hassard B Miller BL
Lambda Theta Reflectometry: A New Technique for Measuring Optical Film Thickness in Planar Protein Arrays. ; ACS sensors. 2025 Jul 02.
Dai N Zhou T Tang WY Mathews DH Huang L
EnsembleDesign: messenger RNA design minimizing ensemble free energy via probabilistic lattice parsing. ; Bioinformatics (Oxford, England); Vol 41(Supplement_1), pp. i391-i400. 2025 Jul 01.
McMahon M Maquat LE
Corrigendum: Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay. ; RNA (New York, N.Y.); Vol 31(7), pp. 1028. 2025 Jun 16.
Das A Ivanov AV Wakabayashi H Grove AK Ermolenko DN
Observing intersubunit dynamics in single yeast ribosomes. ; bioRxiv : the preprint server for biology. 2025 Jun 08.
Walunjkar N Lai TY Akhter N Miller JH Bettinger JQ Marcus E Phizicky EM Ghaemmaghami S Fay JC
Pervasive divergence in protein thermostability is mediated by both structural changes and cellular environments. ; Molecular biology and evolution. 2025 Jun 06.
Abid D Murphy K Murphy Z Rahman N Getman M Steiner L
The Condensin II complex regulates essential gene expression programs during erythropoiesis. ; Development (Cambridge, England); Vol 152(10). 2025 May 19.
Hedaya OM Jiang F Baliga U Ivanov A Chen S Schwartz JL Kawakami Y Yan C Yao P
Upstream open reading frame inactivation augments GATA4 translation and cardiomyocyte hypertrophy in mice. ; bioRxiv : the preprint server for biology. 2025 May 18.
Franchini L Porter JJ Lueck JD Orlandi C
GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization. ; Nature communications; Vol 16(1), pp. 4521. 2025 May 15.
Mathews DH Casadio R Sternberg MJE
Computational Resources for Molecular Biology 2025. ; Journal of molecular biology. 2025 May 15.
Waldern JM Taylor C Giannetti CA Irving PS Allen SR Zhu M Backofen R Mathews DH Weeks KM Laederach A
Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP. ; Nucleic acids research; Vol 53(9). 2025 May 10.
Duarte LS Blumberg N Marvald J Love T Andolina JR Noronha SA Steiner LA Henrichs K Looney RJ Refaai MA Asante A
Differences in outcomes associated with ABO blood groups in recipients of IVIG. ; Blood vessels, thrombosis & hemostasis; Vol 2(3), pp. 100075. 2025 May 09.
Dillingham CM Cormaty H Morgan EC Tak AI Esgdaille DE Boutz PL Sridharan R
KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells. ; iScience; Vol 28(6), pp. 112612. 2025 May 08.
Hao K Nguyen T Nakada Y Walcott G Wei Y Wu Y Garry DJ Yao P Zhang J
Newborn apical resection preserves the proliferative capacity of cardiomyocytes located throughout the left ventricle. ; Stem cells (Dayton, Ohio). 2025 Apr 15.
Baluapuri A Zhao NC Marina RJ Huang KL Kuzkina A Amodeo ME Stein CB Ahn LY Farr JS Schaffer AE Khurana V Wagner EJ Adelman K
Integrator loss leads to dsRNA formation that triggers the integrated stress response. ; Cell. 2025 Apr 10.
Klose AM Katz JD Boni R Nelson D Miller BL
Lambda Theta Reflectometry: a new technique to measure optical film thickness applied to planar protein arrays. ; bioRxiv : the preprint server for biology. 2025 Mar 29.
Berger KD Puthenpeedikakkal AMK Mathews DH Fu D
Structural Impact of 3-methylcytosine Modification on the Anticodon Stem-loop of a Neuronally-enriched Arginine tRNA. ; Journal of molecular biology. 2025 Mar 29.
Bhat SY Bhattacharya A Li H Cui X Lueck JD Goldman YE Cooperman BS
Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases. ; Nucleic acids research; Vol 53(6). 2025 Mar 20.
Thalalla Gamage S Khoogar R Howpay Manage S DaRos JT Crawford MC Georgeson J Polevoda BV Sanders C Lee KA Nance KD Iyer V Kustanovich A Perez M Thu CT Nance SR Amin R Miller CN Holewinski RJ Das S Meyer TJ Koparde V Yang A Jailwala P Nguyen JT Andresson T Hunter K Gu S Mock BA Edmondson EF Difilippantonio S Chari R Schwartz S O'Connell MR Wu CC Meier JL
Transfer RNA acetylation regulates in vivo mammalian stress signaling. ; Science advances; Vol 11(12), pp. eads2923. 2025 Mar 19.
Butman HS Stefaniak MA Walsh DJ Gondil VS Young M Crow AH Nemeth AM Melander RJ Dunman PM Melander C
Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus. ; Bioorganic & medicinal chemistry letters. 2025 Mar 03.
Park BJ Hua S Casler KD Cefaloni E Ayers MC Lake RF Murphy KE Vertino PM O'Connell MR Murphy PJ
CUT&Tag Identifies Repetitive Genomic Loci that are Excluded from ChIP Assays. ; bioRxiv : the preprint server for biology. 2025 Feb 05.
Bucukovski J Miller BL
Everything's under Control: Maximizing Biosensor Performance through Negative Control Probe Selection. ; Analytical chemistry. 2025 Feb 03.
Linares I Chen K Saffren A Mansouri M Abhyankar VV Miller BL Begolo S Awad HA McGrath JL
Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis. ; Scientific reports; Vol 15(1), pp. 3227. 2025 Jan 25.
Stegemann F Marcus E Neupert S Ostrowski S Mathews DH Phizicky EM
Schizosaccharomyces pombe pus1 mutants are temperature sensitive due to decay of tRNAIle(UAU) by the 5'-3' exonuclease Dhp1, primarily targeting the unspliced pre-tRNA. ; RNA (New York, N.Y.). 2025 Jan 23.
Weeden T Picariello T Quinn B Spring S Shen PY Qiu Q Vieira BF Schlaefke L Russo RJ Chang YA Cui J Yao M Wen A Hsia N Evron T Ovington K Tsai PN Yoder N Lan B Venkatesan R Hall J Desjardins CA Qatanani M Hilderbrand S Najim J Tang Z Tanner MK Subramanian R Thornton CA Ibraghimov-Beskrovnaya O Zanotti S
FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models. ; Communications medicine; Vol 5(1), pp. 22. 2025 Jan 18.
Tanu T Cox AM Karlow J Sharma P He X Wu C Babu S Brown J Brown KM Chanock SJ Liu D Zhang T Burns KH Boutz PL Insco ML
Recurrent oncogenic ZC3H18 mutations stabilize endogenous retroviral RNA. ; bioRxiv : the preprint server for biology. 2025 Jan 14.
Provenzano M Ikegami K Bates K Gaynor A Hartman JM Jones AS Butler A Berggren KN Dekdebrun J Hung M Lapato DM Kiefer M Thornton CA Johnson NE Hale MA
The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1. ; The Journal of clinical investigation. 2025 Jan 07.
Wakabayashi H Zhu M Grayhack EJ Mathews DH Ermolenko DN
40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion. ; bioRxiv : the preprint server for biology. 2025 Jan 04.
Zhu M Mathews DH
Sequence Design Using RNAstructure. ; Methods in molecular biology (Clifton, N.J.); Vol 2847, pp. 17-31. 2025.
Pezzini S Mustaccia A Aboa P Faustini G Branchini A Pinotti M Frasca A Porter JJ Lueck JD Landsberger N
Engineered tRNAs efficiently suppress CDKL5 premature termination codons. ; Scientific reports; Vol 14(1), pp. 31791. 2024 Dec 30.
McMahon M Maquat LE
Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay. ; RNA (New York, N.Y.). 2024 Dec 12.
Tang WY Dai N Zhou T Mathews DH Huang L
Sampling-based Continuous Optimization with Coupled Variables for RNA Design. ; ArXiv. 2024 Dec 11.
Porter JJ Ko W Sorensen EG Lueck JD
Optimization of ACE-tRNAs function in translation for suppression of nonsense mutations. ; Nucleic acids research. 2024 Nov 30.
Reed CR Kennedy SD Horowitz RH Keedakkatt Puthenpeedikakkal AM Stern HA Mathews DH
Modeling and NMR Data Elucidate the Structure of a G-Quadruplex-Ligand Interaction for a Pu22T-Cyclometalated Iridium(III) System. ; The journal of physical chemistry. B. 2024 Nov 19.
Berger KD Puthenpeedikakkal AMK Mathews DH Fu D
Structural impact of 3-methylcytosine modification on the anticodon stem of a neuronally-enriched arginine tRNA. ; bioRxiv : the preprint server for biology. 2024 Nov 18.
Ajalik RE Linares I Alenchery RG Zhang VZ Wright TW Miller BL McGrath JL Awad HA
Human Tendon-on-a-Chip for Modeling the Myofibroblast Microenvironment in Peritendinous Fibrosis. ; Advanced healthcare materials. 2024 Nov 15.
Bhat S Bhattacharya A Li H Lueck JD Goldman YE Cooperman BS
Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases. ; bioRxiv : the preprint server for biology. 2024 Nov 14.
Lindley S Subbaiah K Priyanka F Poosala P Ma Y Jalinous L West JA Richardson W Thomas TN Anderson DM
Ribozyme-activated mRNA Trans-ligation Enables Large Gene Delivery to Treat Muscular Dystrophies; Science; Vol 386, pp. 762-767. 2024 Jan 01.
Mittal A Ali SE Mathews DH
Using the RNAstructure Software Package to Predict Conserved RNA Structures. ; Current protocols; Vol 4(11), pp. e70054. 2024 Nov.
Kiliushik D Goenner C Law M Schroeder GM Srivastava Y Jenkins JL Wedekind JE
Knotty is nice: metabolite binding and RNA-mediated gene regulation by the preQ1 riboswitch family. ; The Journal of biological chemistry. 2024 Oct 30.
Courtney E Datta A Mathews DH Ward M
memerna: Sparse RNA Folding Including Coaxial Stacking. ; Journal of molecular biology. 2024 Oct 18.
Iannuzzelli JA Bonn R Hong AS Anitha AS Jenkins JL Wedekind JE Fasan R
Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library. ; Chemical science. 2024 Oct 17.
Srivastava Y Akinyemi O Rohe TC Pritchett EM Baker CD Sharma A Jenkins JL Mathews DH Wedekind JE
Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations. ; Nucleic acids research. 2024 Oct 16.
Zhu M Zuber J Tan Z Sharma G Mathews DH
DecoyFinder: Identification of Contaminants in Sets of Homologous RNA Sequences. ; bioRxiv : the preprint server for biology. 2024 Oct 15.
Maji D Jenkins JL Boutz PL Kielkopf CL
Recurrent Neurodevelopmentally Associated Variants of the Pre-mRNA Splicing Factor U2AF2 Alter RNA Binding Affinities and Interactions. ; Biochemistry. 2024 Oct 10.
Hassel GA eflová J Cho EE Blair SN Van Raamsdonk CD Anderson DM Robia SL Makarewich CA
Another-regulin regulates cardiomyocyte calcium handling via integration of neuroendocrine signaling with SERCA2a activity; J Mol Cell Cardiol. 2024 Jan 01.
Beard JW Hunt SL Evans A Goenner C Miller BL
Mimicking a Cellular Crowding Environment for Enzyme-Free Paper-Based Nucleic Acid Tests at the Point of Care. ; ACS sensors. 2024 Sep 30.
Oberstrass L Tants JN Lichtenthaeler C Ali SE Koch L Mathews DH Schlundt A Weigand J
Comprehensive Profiling of Roquin Binding Preferences for RNA Stem-Loops. ; Angewandte Chemie (International ed. in English). 2024 Sep 30.
Casadio R Mathews DH Sternberg MJE
Computational Resources for Molecular Biology 2024. ; Journal of molecular biology. 2024 Aug 06.
Thalalla Gamage S Khoogar R Howpay Manage S Crawford MC Georgeson J Polevoda BV Sanders C Lee KA Nance KD Iyer V Kustanovich A Perez M Thu CT Nance SR Amin R Miller CN Holewinski RJ Meyer T Koparde V Yang A Jailwala P Nguyen JT Andresson T Hunter K Gu S Mock BA Edmondson EF Difilippantonio S Chari R Schwartz S O'Connell MR Wu CC Meier JL
Transfer RNA acetylation regulates in vivo mammalian stress signaling. ; bioRxiv : the preprint server for biology. 2024 Jul 28.
Franchini L Porter JJ Lueck JD Orlandi C
Gz Enhanced Signal Transduction assaY (G Z ESTY) for GPCR deorphanization. ; bioRxiv : the preprint server for biology. 2024 Jul 26.
Lin MH Jensen MK Elrod ND Chu HF Haseley M Beam AC Huang KL Chiang W Russell WK Williams K Pröschel C Wagner EJ Tong L
Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function. ; Molecular cell. 2024 Jul 08.
Malik A Zhang L Gautam M Dai N Li S Zhang H Mathews DH Huang L
LinearAlifold: Linear-Time Consensus Structure Prediction for RNA Alignments. ; Journal of molecular biology. 2024 Jul 04.
Batebi H Pérez-Hernández G Rahman SN Lan B Kamprad A Shi M Speck D Tiemann JKS Guixà-González R Reinhardt F Stadler PF Papasergi-Scott MM Skiniotis G Scheerer P Kobilka BK Mathiesen JM Liu X Hildebrand PW
Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor. ; Nature structural & molecular biology; Vol 31(11), pp. 1692-1701. 2024 Jun 12.
Morais P Zhang R Yu YT
Therapeutic Nonsense Suppression Modalities: From Small Molecules to Nucleic Acid-Based Approaches. ; Biomedicines; Vol 12(6). 2024 Jun 10.
Gondil VS Butman HS Young M Walsh DJ Narkhede Y Zeiler MJ Crow AH Carpenter ME Mardikar A Melander RJ Wiest O Dunman PM Melander C
Development of phenyl-urea-based small molecules that target penicillin-binding protein 4. ; Chemical biology & drug design; Vol 103(6), pp. e14569. 2024 Jun.
Porter JJ Lueck JD
A cystic fibrosis gene editing approach that is on target. ; Molecular therapy. Nucleic acids; Vol 35(2), pp. 102197. 2024 May 08.
Pan Y Adachi H He X Chen JL Yu YT Boutz PL
Updated Pseudo-seq Protocol for Transcriptome-Wide Detection of Pseudouridines. ; Bio-protocol; Vol 14(9), pp. e4985. 2024 May 05.
Lynch CA Acosta SA Anderson DM Rogers GE Wilson-Rawls J Rawls A
The Transcription Factor Mohawk Facilitates Skeletal Muscle Repair via Modulation of the Inflammatory Environment; Int J Mol Sci 25. 2024 Jan 01.
Rambout X Maquat LE
Nuclear mRNA decay: regulatory networks that control gene expression. ; Nature reviews. Genetics. 2024 Apr 18.
Haugen RJ Barnier C Elrod ND Luo H Jensen MK Ji P Smibert CA Lipshitz HD Wagner EJ Freddolino PL Goldstrohm AC
Regulation of the Drosophila transcriptome by Pumilio and the CCR4-NOT deadenylase complex. ; RNA (New York, N.Y.). 2024 Apr 16.
Bryan MR Butt JN Ding Z Tokranova N Cady N Piorek B Meinhart C Tice J Miller BL
A Multiplex "Disposable Photonics" Biosensor Platform and Its Application to Antibody Profiling in Upper Respiratory Disease. ; ACS sensors. 2024 Mar 29.
Gowtham L Wozniak RAF Dunman PM Sheba E Garg P Joseph J
Efficacy of a Novel Antibiotic Drug Combination Toward Multidrug-Resistant Ocular Pathogens. ; Cornea. 2024 Mar 26.
Mittal A Turner DH Mathews DH
NNDB: An expanded database of nearest neighbor parameters for predicting stability of nucleic acid secondary structures. ; Journal of molecular biology. 2024 Mar 22.
Papasergi-Scott MM Pérez-Hernández G Batebi H Gao Y Eskici G Seven AB Panova O Hilger D Casiraghi M He F Maul L Gmeiner P Kobilka BK Hildebrand PW Skiniotis G
Time-resolved cryo-EM of G-protein activation by a GPCR. ; Nature; Vol 629(8014), pp. 1182-1191. 2024 Mar 13.
Beard JW Hunt SL Evans A Goenner C Miller BL
Mimicking an in cellulo environment for enzyme-free paper-based nucleic acid tests at the point of care. ; bioRxiv : the preprint server for biology. 2024 Feb 29.
He F Wu CG Gao Y Rahman SN Zaoralová M Papasergi-Scott MM Gu TJ Robertson MJ Seven AB Li L Mathiesen JM Skiniotis G
Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor. ; Nature; Vol 626(8001), pp. 1141-1148. 2024 Feb 07.
McGrath KE Koniski AD Murphy K Getman M An HH Schulz VP Kim AR Zhang B Schofield TL Papoin J Blanc L Kingsley PD Westhoff CM Gallagher PG Chou ST Steiner LA Palis J
BMI1 regulates human erythroid self-renewal through both gene repression and gene activation. ; bioRxiv : the preprint server for biology. 2024 Feb 06.
Jonnakuti VS Wagner EJ Maletić-Savatić M Liu Z Yalamanchili HK
PolyAMiner-Bulk is a deep learning-based algorithm that decodes alternative polyadenylation dynamics from bulk RNA-seq data. ; Cell reports methods. 2024 Feb 03.
Alessandrini F Wright M Kurosaki T Maquat LE Kiskinis E
ALS-Associated TDP-43 Dysfunction Compromises UPF1-Dependent mRNA Metabolism Pathways Including Alternative Polyadenylation and 3'UTR Length. ; bioRxiv : the preprint server for biology. 2024 Feb 02.
De Zoysa T Hauke AC Iyer NR Marcus E Ostrowski SM Stegemann F Ermolenko DN Fay JC Phizicky EM
A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay. ; PLoS genetics; Vol 20(1), pp. e1011146. 2024 Jan 31.
Kurosaki T Rambout X Maquat LE
FMRP-mediated spatial regulation of physiologic NMD targets in neuronal cells. ; Genome biology; Vol 25(1), pp. 31. 2024 Jan 23.
Tumenbayar BI Tutino VM Brazzo JA Yao P Bae Y
FAK and p130Cas modulate stiffness-mediated early transcription and cellular metabolism. ; bioRxiv : the preprint server for biology. 2024 Jan 16.
Chen JL Leeder WM Morais P Adachi H Yu YT
Pseudouridylation-mediated gene expression modulation. ; The Biochemical journal; Vol 481(1), pp. 1-16. 2024 Jan 10.
Cisco LA Sipple MT Edwards KM Thornton CA Lueck JD
Verapamil mitigates chloride and calcium bi-channelopathy in a myotonic dystrophy mouse model. ; The Journal of clinical investigation; Vol 134(1). 2024 Jan 02.
Zuber J Mathews DH
Estimating RNA Secondary Structure Folding Free Energy Changes with efn2. ; Methods in molecular biology (Clifton, N.J.); Vol 2726, pp. 1-13. 2024.
Wu J Hollinger J Bonanno E Jiang F Yao P
Cardiomyocyte-Specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy. ; Cells; Vol 13(1). 2023 Dec 22.
Lv X Murphy K Murphy Z Getman MR Rahman NF Nakamura Y Blanc L Gallagher PG Palis J Mohandas N Steiner LA
HEXIM1 is an Essential Transcription Regulator During Human Erythropoiesis. ; Blood. 2023 Sep 22.
Wu J Hollinger J Bonanno E Jiang F Yao P
Cardiomyocyte-specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy. ; bioRxiv : the preprint server for biology. 2023 Sep 22.
De Zoysa T Hauke AC Iyer NR Marcus E Ostrowski SM Fay JC Phizicky EM
A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay. ; bioRxiv : the preprint server for biology. 2023 Sep 18.
Boutz PL
Putting a finger on histidine methylation. ; Genes & development; Vol 37(15-16), pp. 675-677. 2023 Sep 06.
Pham TM Miffin T Sun H Sharp KK Wang X Zhu M Hoshika S Peterson RJ Benner SA Kahn JD Mathews DH
DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters. ; ACS synthetic biology. 2023 Sep 06.
Kosoy G Miller BL
Two Decades of Arrayed Imaging Reflectometry for Sensitive, High-Throughput Biosensing. ; Biosensors; Vol 13(9). 2023 Sep 05.
Schroeder GM Kiliushik D Jenkins JL Wedekind JE
Structure and function analysis of a type III preQ1-I riboswitch from E. coli reveals direct metabolite-sensing by the Shine-Dalgarno sequence. ; The Journal of biological chemistry. 2023 Sep 01.
Zhang H Li S Dai N Zhang L Mathews DH Huang L
LinearCoFold and LinearCoPartition: linear-time algorithms for secondary structure prediction of interacting RNA molecules. ; Nucleic acids research. 2023 Aug 31.
Haugen RJ Barnier C Elrod ND Luo H Jensen MK Ji P Smibert CA Lipshitz HD Wagner EJ Freddolino PL Goldstrohm AC
Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase. ; bioRxiv : the preprint server for biology. 2023 Aug 30.
Moran MC Klose A Yoshida T De Benedetto A Schneider LC Ong PY Simpson EL Leung DYM Miller BL Seplaki CL Beck LA
History of S. aureus Skin Infection Significantly Associates with History of Eczema Herpeticum in Patients with Atopic Dermatitis. ; Dermatology and therapy. 2023 Aug 24.
Wu J Subbaiah KCV Hedaya O Chen S Munger J Tang WHW Yan C Yao P
FAM210A regulates mitochondrial translation and maintains cardiac mitochondrial homeostasis. ; Cardiovascular research. 2023 Jul 31.
Liu L Xu Z Molina Vargas AM Dollery SJ Schrlau MG Cormier D O'Connell MR Tobin GJ Du K
Aerosol Jet Printing-Enabled Dual-Function Electrochemical and Colorimetric Biosensor for SARS-CoV-2 Detection. ; Analytical chemistry. 2023 Jul 28.
Zuber J Sah SK Mathews DH Rustchenko E
Genome-Wide DNA Changes Acquired by Candida albicans Caspofungin-Adapted Mutants. ; Microorganisms; Vol 11(8). 2023 Jul 25.
Kretsch RC Andersen ES Bujnicki JM Chiu W Das R Luo B Masquida B McRae EKS Schroeder GM Su Z Wedekind JE Xu L Zhang K Zheludev IN Moult J Kryshtafovych A
RNA target highlights in CASP15: Evaluation of predicted models by structure providers. ; Proteins. 2023 Jul 19.
Piraino L Chen CY Mereness J Dunman PM Ovitt C Benoit D DeLouise L
Identifying novel radioprotective drugs via salivary gland tissue chip screening. ; bioRxiv : the preprint server for biology. 2023 Jul 13.
Young M Chojnacki M Blanchard C Cao X Johnson WL Flaherty D Dunman PM
Genetic Determinants of Acinetobacter baumannii Serum-Associated Adaptive Efflux-Mediated Antibiotic Resistance. ; Antibiotics (Basel, Switzerland); Vol 12(7). 2023 Jul 11.
Ali SE Mittal A Mathews DH
RNA Secondary Structure Analysis Using RNAstructure. ; Current protocols; Vol 3(7), pp. e846. 2023 Jul.
Jonnakuti VS Ji P Gao Y Lin A Chu Y Elrod N Huang KL Li W Yalamanchili HK Wagner EJ
NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1. ; Journal of neuro-oncology. 2023 Jun 30.
Zhou T Dai N Li S Ward M Mathews DH Huang L
RNA design via structure-aware multifrontier ensemble optimization. ; Bioinformatics (Oxford, England); Vol 39(39 Suppl 1), pp. i563-i571. 2023 Jun 30.
Das A Bao C Ermolenko DN
Comparing FRET Pairs that Report on Intersubunit Rotation in Bacterial Ribosomes. ; Journal of molecular biology; Vol 435(15), pp. 168185. 2023 Jun 20.
Hollinger J Wu J Awayda KM O'Connell MR Yao P
Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli. ; Protein expression and purification; Vol 210, pp. 106322. 2023 Jun 15.
Hedaya OM Subbaiah KCV Jiang F Xie LH Wu J Khor E Zhu M Mathews DH Proschel C Yao P
Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy. ; bioRxiv : the preprint server for biology. 2023 Jun 15.
Pham TM Miffin T Sun H Sharp KK Wang X Zhu M Hoshika S Peterson RJ Benner SA Kahn JD Mathews DH
DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters. ; bioRxiv : the preprint server for biology. 2023 Jun 08.
Cisco LA Sipple MT Edwards KM Thornton CA Lueck JD
Combinatorial chloride and calcium channelopathy in myotonic dystrophy. ; bioRxiv : the preprint server for biology. 2023 Jun 01.
Mathews DH Casadio R Sternberg MJE
Computational Resources for Molecular Biology 2023. ; Journal of molecular biology. 2023 May 25.
Wu J Subbaiah KCV Hedaya O Chen S Munger J Tang WHW Yan C Yao P
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis. ; bioRxiv : the preprint server for biology. 2023 May 22.
Das A Bao C Ermolenko DN
Comparing FRET pairs that report on intersubunit rotation in bacterial ribosomes. ; bioRxiv : the preprint server for biology. 2023 May 09.
Zhang H Zhang L Lin A Xu C Li Z Liu K Liu B Ma X Zhao F Jiang H Chen C Shen H Li H Mathews DH Zhang Y Huang L
Algorithm for Optimized mRNA Design Improves Stability and Immunogenicity. ; Nature. 2023 May 02.
Mirska B Woźniak T Lorent D Ruszkowska A Peterson JM Moss WN Mathews DH Kierzek R Kierzek E
In vivo secondary structural analysis of Influenza A virus genomic RNA. ; Cellular and molecular life sciences : CMLS; Vol 80(5), pp. 136. 2023 May 02.
Jiang F Hedaya OM Khor E Wu J Auguste M Yao P
RNA binding protein PRRC2B mediates translation of specific mRNAs and regulates cell cycle progression. ; Nucleic acids research. 2023 May 01.
VanderWal AR Park JU Polevoda B Nicosia JK Molina Vargas AM Kellogg EH O'Connell MR
Csx28 is a membrane pore that enhances CRISPR-Cas13b-dependent antiphage defense. ; Science (New York, N.Y.); Vol 380(6643), pp. 410-415. 2023 Apr 27.
Insco ML Abraham BJ Dubbury SJ Kaltheuner IH Dust S Wu C Chen KY Liu D Bellaousov S Cox AM Martin BJE Zhang T Ludwig CG Fabo T Modhurima R Esgdaille DE Henriques T Brown KM Chanock SJ Geyer M Adelman K Sharp PA Young RA Boutz PL Zon LI
Oncogenic CDK13 mutations impede nuclear RNA surveillance. ; Science (New York, N.Y.); Vol 380(6642), pp. eabn7625. 2023 Apr 21.
Zhou T Gilliam NJ Li S Spandau S Osborn RM Connor S Anderson CS Mariani TJ Thakar J Dewhurst S Mathews DH Huang L Sun Y
Generation and Functional Analysis of Defective Viral Genomes during SARS-CoV-2 Infection. ; mBio. 2023 Apr 19.
Phizicky EM Hopper AK
The Life and Times of a tRNA. ; RNA (New York, N.Y.). 2023 Apr 13.
Das A Adiletta N Ermolenko DN
Interplay between Inter-Subunit Rotation of the Ribosome and Binding of Translational GTPases. ; International journal of molecular sciences; Vol 24(8). 2023 Apr 07.
Wedekind JE
RNA in the loop: Probing T-loop/T-loop receptor interactions as mediators of long-range RNA contacts that influence gene regulation. ; Journal of molecular biology. 2023 Apr 06.
Tepe B Macke EL Niceta M Weisz Hubshman M Kanca O Schultz-Rogers L Zarate YA Schaefer GB Granadillo De Luque JL Wegner DJ Cogne B Gilbert-Dussardier B Le Guillou X Wagner EJ Pais LS Neil JE Mochida GH Walsh CA Magal N Drasinover V Shohat M Schwab T Schmitz C Clark K Fine A Lanpher B Gavrilova R Blanc P Burglen L Afenjar A Steel D Kurian MA Prabhakar P Gößwein S Di Donato N Bertini ES Wangler MF Yamamoto S Tartaglia M Klee EW Bellen HJ
Bi-allelic variants in INTS11 are associated with a complex neurological disorder. ; American journal of human genetics. 2023 Apr 04.
Passaro VMN Semenova Y Miller BL
Feature Papers in Optical Sensors 2022. ; Sensors (Basel, Switzerland); Vol 23(7). 2023 Apr 03.
Papasergi-Scott MM Pérez-Hernández G Batebi H Gao Y Eskici G Seven AB Panova O Hilger D Casiraghi M He F Maul L Gmeiner P Kobilka BK Hildebrand PW Skiniotis G
Time-resolved cryo-EM of G protein activation by a GPCR. ; bioRxiv : the preprint server for biology. 2023 Mar 21.
Papasergi-Scott MM Kwarcinski FE Yu M Panova O Ovrutsky AM Skiniotis G Tall GG
Structures of Ric-8B in complex with Gα protein folding clients reveal isoform specificity mechanisms. ; Structure (London, England : 1993); Vol 31(5), pp. 553-564.e7. 2023 Mar 16.
Thornton CA Moxley RT Eichinger K Heatwole C Mignon L Arnold WD Ashizawa T Day JW Dent G Tanner MK Duong T Greene EP Herbelin L Johnson NE King W Kissel JT Leung DG Lott DJ Norris DA Pucillo EM Schell W Statland JM Stinson N Subramony SH Xia S Bishop KM Bennett CF
Antisense oligonucleotide targeting DMPK in patients with myotonic dystrophy type 1: a multicentre, randomised, dose-escalation, placebo-controlled, phase 1/2a trial. ; The Lancet. Neurology; Vol 22(3), pp. 218-228. 2023 Mar.
de Prisco N Ford C Elrod ND Lee W Tang LC Huang KL Lin A Ji P Jonnakuti VS Boyle L Cabaj M Botta S Õunap K Reinson K Wojcik MH Rosenfeld JA Bi W Tveten K Prescott T Gerstner T Schroeder A Fong CT George-Abraham JK Buchanan CA Hanson-Khan A Bernstein JA Nella AA Chung WK Brandt V Jovanovic M Targoff KL Yalamanchili HK Wagner EJ Gennarino VA
Alternative polyadenylation alters protein dosage by switching between intronic and 3'UTR sites. ; Science advances; Vol 9(7), pp. eade4814. 2023 Feb 17.
Bryan MR Butt JN Bucukovski J Miller BL
Biosensing with Silicon Nitride Microring Resonators Integrated with an On-Chip Filter Bank Spectrometer. ; ACS sensors. 2023 Feb 14.
Knott GJ Lapinaite A O'Connell MR
Methods special issue: RNA-targeting technologies. ; Methods (San Diego, Calif.); Vol 212, pp. 10-11. 2023 Feb 13.
Schroeder GM Akinyemi O Malik J Focht CM Pritchett EM Baker CD McSally JP Jenkins JL Mathews DH Wedekind JE
A riboswitch separated from its ribosome-binding site still regulates translation. ; Nucleic acids research. 2023 Feb 10.
Klose AM Kosoy G Miller BL
Arrayed Imaging Reflectometry monitoring of anti-viral antibody production throughout vaccination and breakthrough Covid-19. ; PloS one; Vol 18(2), pp. e0277846. 2023 Feb 07.
Adachi H Pan Y He X Chen JL Klein B Platenburg G Morais P Boutz P Yu YT
Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes. ; Molecular cell. 2023 Feb 03.
Cui Y Arnold FJ Peng F Wang D Li JS Michels S Wagner EJ La Spada AR Li W
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. ; Nature communications; Vol 14(1), pp. 583. 2023 Feb 03.
Molina Vargas AM Sinha S Osborn R Arantes PR Patel A Dewhurst S Hardy DJ Cameron A Palermo G O'Connell MR
New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity. ; Nucleic acids research. 2023 Jan 30.
Sinha S Molina Vargas AM Arantes PR Patel A O'Connell MR Palermo G
Unveiling the RNA-mediated allosteric activation discloses functional hotspots in CRISPR-Cas13a. ; Nucleic acids research. 2023 Jan 30.
Subbaiah KCV Wu J Tang WHW Yao P
Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis. ; Journal of cardiovascular development and disease; Vol 10(2). 2023 Jan 29.
Jonnakuti VS Wagner EJ Maletić-Savatić M Liu Z Yalamanchili HK
PolyAMiner-Bulk: A Machine Learning Based Bioinformatics Algorithm to Infer and Decode Alternative Polyadenylation Dynamics from bulk RNA-seq data. ; bioRxiv : the preprint server for biology. 2023 Jan 24.
Farovitch L Padden C vanWijngaarden E Miller B Leydet B Dye T
Attitudes and experiences regarding preventive strategies for the deaf population in Western New York. ; PLOS global public health; Vol 3(11), pp. e0001056. 2023 Jan 22.
Fongang B Wadop YN Zhu Y Wagner EJ Kudlicki A Rowicka M
Coevolution combined with molecular dynamics simulations provides structural and mechanistic insights into the interactions between the integrator complex subunits. ; Computational and structural biotechnology journal; Vol 21, pp. 5686-5697. 2023 Jan 19.
Rambout X Cho H Blanc R Lyu Q Miano JM Chakkalakal JV Nelson GM Yalamanchili HK Adelman K Maquat LE
PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII. ; Molecular cell; Vol 83(2), pp. 186-202.e11. 2023 Jan 19.
Allaire NE Griesenbach U Kerem B Lueck JD Stanleigh N Oren YS
Gene, RNA, and ASO-based therapeutic approaches in Cystic Fibrosis. ; Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 2023 Jan 17.
Liu S Baeg GH Yang Y Goh FG Bao H Wagner EJ Yang X Cai Y
The Integrator complex desensitizes cellular response to TGF-β/BMP signaling. ; Cell reports; Vol 42(1), pp. 112007. 2023 Jan 14.
King KA Benton AH Caudill MT Stoyanof ST Kang L Michalak P Lahmers KK Dunman PM DeHart TG Ahmad SS Jutras BL Poncin K De Bolle X Caswell CC
Post-transcriptional control of the essential enzyme MurF by a small regulatory RNA in Brucella abortus. ; Molecular microbiology. 2023 Jan 11.
Srivastava Y Blau ME Jenkins JL Wedekind JE
Full-Length NAD+-I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate. ; Biochemistry. 2023 Jan 10.
Rook ML McCullock TW Couch T Lueck JD MacLean DM
Photomodulation of the ASIC1a acidic pocket destabilizes the open state. ; Protein science : a publication of the Protein Society. 2023 Jan 08.
Papoin J Yan H Leduc M Le Gall M Narla A Palis J Steiner LA Gallagher PG Hillyer CD Gautier EF Mohandas N Blanc L
Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways. ; American journal of hematology. 2023 Jan 06.
Wagner EJ Tong L Adelman K
Integrator is a global promoter-proximal termination complex. ; Molecular cell. 2023 Jan 04.
Cognetti JS Moen MT Brewer MG Bryan MR Tice JD McGrath JL Miller BL
A photonic biosensor-integrated tissue chip platform for real-time sensing of lung epithelial inflammatory markers. ; Lab on a chip. 2023 Jan 03.
Hedaya OM Venkata Subbaiah KC Jiang F Xie LH Wu J Khor ES Zhu M Mathews DH Proschel C Yao P
Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy. ; Nature communications; Vol 14(1), pp. 6166. 2023 Jan 03.
Adachi H Chen JL Yin Q Morais P Yu YT
In Vitro Reconstitution of Pseudouridylation Catalyzed by Human Box H/ACA Ribonucleoprotein Particles. ; Methods in molecular biology (Clifton, N.J.); Vol 2666, pp. 177-191. 2023.
Cavender CE Schroeder GM Mathews DH Wedekind JE
Isothermal Titration Calorimetry Analysis of a Cooperative Riboswitch Using an Interdependent-Sites Binding Model. ; Methods in molecular biology (Clifton, N.J.); Vol 2568, pp. 53-73. 2023.
Zhang H Zhang L Liu K Li S Mathews DH Huang L
Linear-Time Algorithms for RNA Structure Prediction. ; Methods in molecular biology (Clifton, N.J.); Vol 2586, pp. 15-34. 2023.
Robertson MJ Papasergi-Scott MM He F Seven AB Meyerowitz JG Panova O Peroto MC Che T Skiniotis G
Structure determination of inactive-state GPCRs with a universal nanobody. ; Nature structural & molecular biology; Vol 29(12), pp. 1188-1195. 2022 Nov 17.
Lin MH Jensen MK Elrod ND Huang KL Welle KA Wagner EJ Tong L
Inositol hexakisphosphate is required for Integrator function. ; Nature communications; Vol 13(1), pp. 5742. 2022 Sep 30.
Guo B Friedland SC Alexander W Myers JA Wang W O'Dell MR Getman M Whitney-Miller CL Agostini-Vulaj D Huber AR Mello SS Vertino PM Land HK Steiner LA Hezel AF
Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma. ; Cell reports; Vol 40(9), pp. 111253. 2022 Aug 30.
Hogestyn JM Salois G Xie L Apa C Youngyunpipatkul J Pröschel C Mayer-Pröschel M
Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells. ; Molecular and cellular neurosciences. 2022 Aug 30.
Joseph Davis Burris B Moises Molina Vargas A Park BJ O'Connell MR
Optimization of specific RNA knockdown in mammalian cells with CRISPR-Cas13. ; Methods (San Diego, Calif.). 2022 Aug 17.
Tasak M Phizicky EM
Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay path way in evolutionarily distant yeast species. ; PLoS genetics; Vol 18(7), pp. e1010215. 2022 Jul 28.
Hamel JI McDermott MP Hilbert JE Martens WB Luebbe E Tawil R Moxley RT Thornton CA
Milestones of progression in myotonic dystrophy type 1 and type 2. ; Muscle & nerve. 2022 Jul 01.
Galardi JW Bela VN Jeffery N He X Glasser E Loerch S Jenkins JL Pulvino MJ Boutz PL Kielkopf CL
A UHM - ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing. ; The Journal of biological chemistry. 2022 Jun 30.
Szikszai M Wise M Datta A Ward M Mathews DH
Deep learning models for RNA secondary structure prediction (probably) do not generalise across families. ; Bioinformatics (Oxford, England). 2022 Jun 24.
Ko W Porter JJ Sipple MT Edwards KM Lueck JD
Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs. ; Molecular therapy. Nucleic acids; Vol 28. 2022 Jun 14.
Kumar J Lackey L Waldern JM Dey A Mustoe AM Weeks K Mathews DH Laederach A
Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing. ; eLife; Vol 11. 2022 Jun 13.
Subbaiah KCV Wu J Tang WHW Yao P
FAM114A1 influences cardiac pathological remodeling by regulating angiotensin II signaling. ; JCI insight. 2022 Jun 07.
Tseng V Collum SD Allawzi A Crotty K Yeligar S Trammell A Ryan Smith M Kang BY Sutliff RL Ingram JL Jyothula SSSK Thandavarayan RA Huang HJ Nozik ES Wagner EJ Michael Hart C Karmouty-Quintana H
3'UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension. ; Matrix biology : journal of the International Society for Matrix Biology; Vol 111, pp. 53-75. 2022 Jun 04.
Cho H Abshire ET Popp MW Pröschel C Schwartz JL Yeo GW Maquat LE
AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay. ; Molecular cell. 2022 Jun 03.
Wilson C Mertens TC Shivshankar P Bi W Collum SD Wareing N Ko J Weng T Naikawadi RP Wolters PJ Maire P Jyothula SS Thandavarayan RA Ren D Elrod ND Wagner EJ Huang HJ Dickey BF Ford HL Karmouty-Quintana H
Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis. ; JCI insight; Vol 7(10). 2022 May 23.
Mackenzie SJ Hamel J Thornton CA
Benefits of aerobic exercise in myotonic dystrophy type 1. ; The Journal of clinical investigation; Vol 132(10). 2022 May 16.
Szabat M Prochota M Kierzek R Kierzek E Mathews DH
A Test and Refinement of Folding Free Energy Nearest Neighbor Parameters for RNA Including N6-Methyladenosine. ; Journal of molecular biology. 2022 May 16.
Casadio R Mathews DH Sternberg MJE
Computational Resources for Molecular Biology 2022. ; Journal of molecular biology. 2022 May 12.
Maquat L Johnson R Valadkhan S Carninci P
Lessons from the functional characterization of lncRNAs: introduction to mammalian genome special issue. ; Mammalian genome : official journal of the International Mammalian Genome Society. 2022 May 09.
Glasser E Maji D Biancon G Puthenpeedikakkal AMK Cavender CE Tebaldi T Jenkins JL Mathews DH Halene S Kielkopf CL
Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. ; Nucleic acids research. 2022 May 07.
Zuber J Schroeder SJ Sun H Turner DH Mathews DH
Nearest neighbor rules for RNA helix folding thermodynamics: improved end effects. ; Nucleic acids research. 2022 May 07.
Mei JA Johnson W Kinn B Laskey E Nolin L Bhamare P Stalker C Dunman PM Wozniak RAF
Antimicrobial Activity of a Triple Antibiotic Combination Toward Ocular Pseudomonas aeruginosa Clinical Isolates. ; Translational vision science & technology; Vol 11(5). 2022 May 02.
Luta EP Miller BL
Development of Methods for Specific Capture of Biological Targets on Aluminum Substrates: Application to Bacillus subtilis Spore Detection as a Model for Anthrax. ; Sensors (Basel, Switzerland); Vol 22(9). 2022 Apr 30.
Funk HM DiVita DJ Sizemore HE Wehrle K Miller CLW Fraley ME Mullins AK Guy AR Phizicky EM Guy MP
Identification of a Trm732 Motif Required for 2'-O-methylation of the tRNA Anticodon Loop by Trm7. ; ACS omega; Vol 7(16). 2022 Apr 26.
Hamel J Creigh PD Dekdebrun J Eichinger K Thornton CA
Remote Assessment of Myotonic Dystrophy Type 1: A Feasibility Study. ; Muscle & nerve. 2022 Apr 15.
Brewer MG Monticelli SR Moran MC Miller BL Beck LA Ward BM
Conditions That Simulate the Environment of Atopic Dermatitis Enhance Susceptibility of Human Keratinocytes to Vaccinia Virus. ; Cells; Vol 11(8). 2022 Apr 14.
Barros-Álvarez X Nwokonko RM Vizurraga A Matzov D He F Papasergi-Scott MM Robertson MJ Panova O Yardeni EH Seven AB Kwarcinski FE Su H Peroto MC Meyerowitz JG Shalev-Benami M Tall GG Skiniotis G
The tethered peptide activation mechanism of adhesion GPCRs. ; Nature; Vol 604(7907), pp. 757-762. 2022 Apr 13.
Walker EJ Bettinger JQ Welle KA Hryhorenko JR Molina Vargas AM O'Connell MR Ghaemmaghami S
Protein folding stabilities are a major determinant of oxidation rates for buried methionine residues. ; The Journal of biological chemistry. 2022 Mar 25.
Kierzek E Zhang X Watson RM Kennedy SD Szabat M Kierzek R Mathews DH
Secondary structure prediction for RNA sequences including N6-methyladenosine. ; Nature communications; Vol 13(1). 2022 Mar 11.
Szutkowska B Wieczorek K Kierzek R Zmora P Peterson JM Moss WN Mathews DH Kierzek E
Secondary Structure of Influenza A Virus Genomic Segment 8 RNA Folded in a Cellular Environment. ; International journal of molecular sciences; Vol 23(5). 2022 Feb 23.
Bao C Zhu M Nykonchuk I Wakabayashi H Mathews DH Ermolenko DN
Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation. ; Nature communications; Vol 13(1). 2022 Feb 21.
Deutsch GK Hagerman KA Sampson J Dent G Dekdebrun J Parker DM Thornton CA Heatwole CR Subramony SH Mankodi AK Ashizawa T Statland JM Arnold WD Moxley RT Day JW
Brief assessment of cognitive function in myotonic dystrophy: multicenter longitudinal study using computer-assisted evaluation. ; Muscle & nerve. 2022 Feb 18.
Broly M Polevoda BV Awayda KM Tong N Lentini J Besnard T Deb W O'Rourke D Baptista J Ellard S Almannai M Hashem M Abdulwahab F Shamseldin H Al-Tala S Alkuraya FS Leon A van Loon RLE Ferlini A Sanchini M Bigoni S Ciorba A van Bokhoven H Iqbal Z Al-Maawali A Al-Murshedi F Ganesh A Al-Mamari W Lim SC Pais LS Brown N Riazuddin S Bézieau S Fu D Isidor B Cogné B O'Connell MR
THUMPD1 bi-allelic variants cause loss of tRNA acetylation and a syndromic neurodevelopmental disorder. ; American journal of human genetics. 2022 Feb 11.
LaForce GR Farr JS Liu J Akesson C Gumus E Pinkard O Miranda HC Johnson K Sweet TJ Ji P Lin A Coller J Philippidou P Wagner EJ Schaffer AE
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration. ; Neuron. 2022 Feb 04.
Embong AK Nguyen-Contant P Wang J Kanagaiah P Chaves FA Fitzgerald TF Zhou Q Kosoy G Branche AR Miller BL Zand MS Sangster MY Topham DJ
Formation and Expansion of Memory B Cells against Coronavirus in Acutely Infected COVID-19 Individuals. ; Pathogens (Basel, Switzerland); Vol 11(2). 2022 Jan 29.
Stein CB Field AR Mimoso CA Zhao C Huang KL Wagner EJ Adelman K
Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci. ; Molecular cell. 2022 Jan 28.
Waitkus J Chang Y Liu L Puttaswamy SV Chung T Vargas AMM Dollery SJ O'Connell MR Cai H Tobin GJ Bhalla N Du K
Gold Nanoparticle Enabled Localized Surface Plasmon Resonance on Unique Gold Nanomushroom Structures for On-Chip CRISPR-Cas13a Sensing. ; Advanced materials interfaces; Vol 10(1). 2022 Jan 27.