Publications
Publications
- Keeping cells fit.; Science (New York, N.Y.); Vol 391(6786), pp. 657-658. 2026 Feb 12.
- Anticodon-edited transfer RNAs (ACE-tRNAs) encoded as therapeutic nonviral minimal DNA vectors.; Nucleic acids research; Vol 54(4). 2026 Feb 05.
- A multi-readout photonic sensor for rapid diagnosis of Von Willebrand disease.; Npj biosensing; Vol 3(1), pp. 7. 2026 Feb 02.
- Theory, Algorithms, and Applications for Identification of Undesignable RNA Secondary Structures and Motifs.; Journal of computational biology : a journal of computational molecular cell biology; Vol 33(1), pp. 134-167. 2026 Jan 30.
- Computational design of generalist cyclopropanases with stereodivergent selectivity.; Nature communications. 2026 Jan 26.
- SF3B1 Phosphorylation Prompts U2AF2 Dissociation for Widespread Control of pre-mRNA Splicing.; bioRxiv : the preprint server for biology. 2026 Jan 20.
- Deep Learning for RNA Secondary Structure Determination: Gauging Generalizability and Broadening the Scope of Traditional Methods.; RNA (New York, N.Y.). 2026 Jan 09.
- QuickDraw: detecting HIV in whole blood using an integrated paper-based consumable that enables direct amplification of purified RNA from paper.; Lab on a chip. 2026 Jan 05.
- Anticodon-edited tRNA enables translational readthrough of COL4A5 premature termination codons.; PloS one; Vol 20(12), pp. e0330804. 2025 Dec 19.
- HIV-1 infection regulates gene expression by altering alternative polyadenylation correlated with CPSF6 and CPSF5 redistribution.; mBio. 2025 Dec 17.
- TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS.; Neuron. 2025 Dec 12.
- Establishing biomarkers and clinical endpoints in myotonic dystrophy type 1 (END-DM1): Protocol of an international natural history study.; PloS one; Vol 20(12), pp. e0331163. 2025 Dec 11.
- Gene regulation through exon junction complex modularity.; Nature structural & molecular biology. 2025 Dec 03.
- NMR and molecular dynamics demonstrate the RNA internal loop GAGU is dynamic and adjacent base pairs determine conformational preference.; Biophysical journal. 2025 Nov 18.
- An smFRET assay to probe the impact of antibiotics on intersubunit rotation in eukaryotic ribosomes.; Methods in enzymology; Vol 725, pp. 77-103. 2025 Nov 11.
- Deep Learning for RNA Secondary Structure Determination: Gauging Generalizability and Broadening the Scope of Traditional Methods.; bioRxiv : the preprint server for biology. 2025 Nov 07.
- CUT&Tag overcomes biases of ChIP and establishes chromatin patterns for repetitive genomic loci.; iScience; Vol 28(11), pp. 113757. 2025 Oct 13.
- Salivary gland tissue chip screening identifies candidate radioprotective drugs.; Communications medicine; Vol 5(1), pp. 420. 2025 Oct 09.
- Subnuclear organization and mislocalization of plasmids reduce transgene expression.; Molecular therapy. Nucleic acids; Vol 36(4), pp. 102730. 2025 Oct 09.
- Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments.; mSphere. 2025 Sep 23.
- Elimination of myotonia improves myopathy in a muscleblind knockout model of myotonic dystrophy.; bioRxiv : the preprint server for biology. 2025 Sep 21.
- A Ψ-Ψ codon-anticodon pairing in nonsense suppression and translational recoding.; Nature chemical biology. 2025 Sep 12.
- Anticodon Edited Transfer RNAs (ACE-tRNAs) Encoded as Therapeutic Nonviral Minimal DNA Vectors.; bioRxiv : the preprint server for biology. 2025 Sep 06.
- Study of Testosterone and Recombinant Human Growth Hormone in Facioscapulohumeral Muscular Dystrophy.; Neurology. Genetics; Vol 11(5), pp. e200292. 2025 Aug 27.
- Real-Time, Continuous Monitoring of Tissue Chips as an Emerging Opportunity for Biosensing.; Sensors (Basel, Switzerland); Vol 25(16). 2025 Aug 19.
- BMI1 regulates human erythroid self-renewal through both gene repression and gene activation.; Nature communications; Vol 16(1), pp. 7619. 2025 Aug 15.
- Translational Control in Cardiac Pathophysiology and Therapeutic Development: When mRNA Meets the Heart.; International journal of molecular sciences; Vol 26(16). 2025 Aug 14.
- HIV-1 Infection Regulates Gene Expression by Altering Alternative Polyadenylation Through CPSF6 and CPSF5 Delocalization.; bioRxiv : the preprint server for biology. 2025 Aug 07.
- 40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion.; RNA (New York, N.Y.). 2025 Jul 31.
- AlignmentFold and AlignmentPartition: Improving the align-then-fold approach for RNA secondary structure prediction.; bioRxiv : the preprint server for biology. 2025 Jul 28.
- Histone H4 lysine 20 methylation marks genes dynamically regulated during erythroid maturation.; Epigenetics & chromatin; Vol 18(1), pp. 48. 2025 Jul 26.
- A Dual-Readout Photonic Sensor for Simultaneous Measurement of Enzyme Activity and Concentration.; ACS sensors. 2025 Jul 24.
- ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosis.; Nucleic acids research; Vol 53(13). 2025 Jul 08.
- FMRP drives mRNP targets into translationally silenced complexes.; Molecular cell. 2025 Jul 08.
- Lambda Theta Reflectometry: A New Technique for Measuring Optical Film Thickness in Planar Protein Arrays.; ACS sensors. 2025 Jul 02.
- EnsembleDesign: messenger RNA design minimizing ensemble free energy via probabilistic lattice parsing.; Bioinformatics (Oxford, England); Vol 41(Supplement_1), pp. i391-i400. 2025 Jul 01.
- Corrigendum: Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay.; RNA (New York, N.Y.); Vol 31(7), pp. 1028. 2025 Jun 16.
- Observing intersubunit dynamics in single yeast ribosomes.; bioRxiv : the preprint server for biology. 2025 Jun 08.
- Pervasive divergence in protein thermostability is mediated by both structural changes and cellular environments.; Molecular biology and evolution. 2025 Jun 06.
- The Condensin II complex regulates essential gene expression programs during erythropoiesis.; Development (Cambridge, England); Vol 152(10). 2025 May 19.
- Upstream open reading frame inactivation augments GATA4 translation and cardiomyocyte hypertrophy in mice.; bioRxiv : the preprint server for biology. 2025 May 18.
- GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization.; Nature communications; Vol 16(1), pp. 4521. 2025 May 15.
- Computational Resources for Molecular Biology 2025.; Journal of molecular biology. 2025 May 15.
- Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP.; Nucleic acids research; Vol 53(9). 2025 May 10.
- Differences in outcomes associated with ABO blood groups in recipients of IVIG.; Blood vessels, thrombosis & hemostasis; Vol 2(3), pp. 100075. 2025 May 09.
- KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells.; iScience; Vol 28(6), pp. 112612. 2025 May 08.
- Newborn apical resection preserves the proliferative capacity of cardiomyocytes located throughout the left ventricle.; Stem cells (Dayton, Ohio). 2025 Apr 15.
- Integrator loss leads to dsRNA formation that triggers the integrated stress response.; Cell. 2025 Apr 10.
- Lambda Theta Reflectometry: a new technique to measure optical film thickness applied to planar protein arrays.; bioRxiv : the preprint server for biology. 2025 Mar 29.
- Structural Impact of 3-methylcytosine Modification on the Anticodon Stem-loop of a Neuronally-enriched Arginine tRNA.; Journal of molecular biology. 2025 Mar 29.
- Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases.; Nucleic acids research; Vol 53(6). 2025 Mar 20.
- Transfer RNA acetylation regulates in vivo mammalian stress signaling.; Science advances; Vol 11(12), pp. eads2923. 2025 Mar 19.
- Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus.; Bioorganic & medicinal chemistry letters. 2025 Mar 03.
- CUT&Tag Identifies Repetitive Genomic Loci that are Excluded from ChIP Assays.; bioRxiv : the preprint server for biology. 2025 Feb 05.
- Everything's under Control: Maximizing Biosensor Performance through Negative Control Probe Selection.; Analytical chemistry. 2025 Feb 03.
- Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis.; Scientific reports; Vol 15(1), pp. 3227. 2025 Jan 25.
- Schizosaccharomyces pombe pus1 mutants are temperature sensitive due to decay of tRNAIle(UAU) by the 5'-3' exonuclease Dhp1, primarily targeting the unspliced pre-tRNA.; RNA (New York, N.Y.). 2025 Jan 23.
- FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models.; Communications medicine; Vol 5(1), pp. 22. 2025 Jan 18.
- Recurrent oncogenic ZC3H18 mutations stabilize endogenous retroviral RNA.; bioRxiv : the preprint server for biology. 2025 Jan 14.
- The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1.; The Journal of clinical investigation. 2025 Jan 07.
- 40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion.; bioRxiv : the preprint server for biology. 2025 Jan 04.
- Sequence Design Using RNAstructure.; Methods in molecular biology (Clifton, N.J.); Vol 2847, pp. 17-31. 2025.
- Engineered tRNAs efficiently suppress CDKL5 premature termination codons.; Scientific reports; Vol 14(1), pp. 31791. 2024 Dec 30.
- Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay.; RNA (New York, N.Y.). 2024 Dec 12.
- Sampling-based Continuous Optimization with Coupled Variables for RNA Design.; ArXiv. 2024 Dec 11.
- Optimization of ACE-tRNAs function in translation for suppression of nonsense mutations.; Nucleic acids research. 2024 Nov 30.
- Modeling and NMR Data Elucidate the Structure of a G-Quadruplex-Ligand Interaction for a Pu22T-Cyclometalated Iridium(III) System.; The journal of physical chemistry. B. 2024 Nov 19.
- Structural impact of 3-methylcytosine modification on the anticodon stem of a neuronally-enriched arginine tRNA.; bioRxiv : the preprint server for biology. 2024 Nov 18.
- Human Tendon-on-a-Chip for Modeling the Myofibroblast Microenvironment in Peritendinous Fibrosis.; Advanced healthcare materials. 2024 Nov 15.
- Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases.; bioRxiv : the preprint server for biology. 2024 Nov 14.
- The TRIM-NHL RNA-binding protein Brain Tumor coordinately regulates expression of the glycolytic pathway and vacuolar ATPase complex.; Nucleic acids research; Vol 52(20), pp. 12669-12688. 2024 Nov 11.
- Ribozyme-activated mRNA Trans-ligation Enables Large Gene Delivery to Treat Muscular Dystrophies; Science; Vol 386, pp. 762-767. 2024 Jan 01.
- Using the RNAstructure Software Package to Predict Conserved RNA Structures.; Current protocols; Vol 4(11), pp. e70054. 2024 Nov.
- Knotty is nice: metabolite binding and RNA-mediated gene regulation by the preQ1 riboswitch family.; The Journal of biological chemistry. 2024 Oct 30.
- memerna: Sparse RNA Folding Including Coaxial Stacking.; Journal of molecular biology. 2024 Oct 18.
- Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library.; Chemical science. 2024 Oct 17.
- Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations.; Nucleic acids research. 2024 Oct 16.
- DecoyFinder: Identification of Contaminants in Sets of Homologous RNA Sequences.; bioRxiv : the preprint server for biology. 2024 Oct 15.
- Recurrent Neurodevelopmentally Associated Variants of the Pre-mRNA Splicing Factor U2AF2 Alter RNA Binding Affinities and Interactions.; Biochemistry. 2024 Oct 10.
- Another-regulin regulates cardiomyocyte calcium handling via integration of neuroendocrine signaling with SERCA2a activity; J Mol Cell Cardiol. 2024 Jan 01.
- Mimicking a Cellular Crowding Environment for Enzyme-Free Paper-Based Nucleic Acid Tests at the Point of Care.; ACS sensors. 2024 Sep 30.
- Comprehensive Profiling of Roquin Binding Preferences for RNA Stem-Loops.; Angewandte Chemie (International ed. in English). 2024 Sep 30.
- Computational Resources for Molecular Biology 2024.; Journal of molecular biology. 2024 Aug 06.
- Transfer RNA acetylation regulates in vivo mammalian stress signaling.; bioRxiv : the preprint server for biology. 2024 Jul 28.
- Gz Enhanced Signal Transduction assaY (G Z ESTY) for GPCR deorphanization.; bioRxiv : the preprint server for biology. 2024 Jul 26.
- Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.; Molecular cell. 2024 Jul 08.
- LinearAlifold: Linear-Time Consensus Structure Prediction for RNA Alignments.; Journal of molecular biology. 2024 Jul 04.
- Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor.; Nature structural & molecular biology; Vol 31(11), pp. 1692-1701. 2024 Jun 12.
- Therapeutic Nonsense Suppression Modalities: From Small Molecules to Nucleic Acid-Based Approaches.; Biomedicines; Vol 12(6). 2024 Jun 10.
- Development of phenyl-urea-based small molecules that target penicillin-binding protein 4.; Chemical biology & drug design; Vol 103(6), pp. e14569. 2024 Jun.
- A UL26-PIAS1 complex antagonizes anti-viral gene expression during Human Cytomegalovirus infection.; PLoS pathogens; Vol 20(5), pp. e1012058. 2024 May 20.
- A cystic fibrosis gene editing approach that is on target.; Molecular therapy. Nucleic acids; Vol 35(2), pp. 102197. 2024 May 08.
- Updated Pseudo-seq Protocol for Transcriptome-Wide Detection of Pseudouridines.; Bio-protocol; Vol 14(9), pp. e4985. 2024 May 05.
- The Transcription Factor Mohawk Facilitates Skeletal Muscle Repair via Modulation of the Inflammatory Environment; Int J Mol Sci 25. 2024 Jan 01.
- Nuclear mRNA decay: regulatory networks that control gene expression.; Nature reviews. Genetics. 2024 Apr 18.
- Regulation of the Drosophila transcriptome by Pumilio and the CCR4-NOT deadenylase complex.; RNA (New York, N.Y.). 2024 Apr 16.
- A Multiplex "Disposable Photonics" Biosensor Platform and Its Application to Antibody Profiling in Upper Respiratory Disease.; ACS sensors. 2024 Mar 29.
- Efficacy of a Novel Antibiotic Drug Combination Toward Multidrug-Resistant Ocular Pathogens.; Cornea. 2024 Mar 26.
- NNDB: An expanded database of nearest neighbor parameters for predicting stability of nucleic acid secondary structures.; Journal of molecular biology. 2024 Mar 22.
- Time-resolved cryo-EM of G-protein activation by a GPCR.; Nature; Vol 629(8014), pp. 1182-1191. 2024 Mar 13.
- Mimicking an in cellulo environment for enzyme-free paper-based nucleic acid tests at the point of care.; bioRxiv : the preprint server for biology. 2024 Feb 29.
- Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor.; Nature; Vol 626(8001), pp. 1141-1148. 2024 Feb 07.
- BMI1 regulates human erythroid self-renewal through both gene repression and gene activation.; bioRxiv : the preprint server for biology. 2024 Feb 06.
- PolyAMiner-Bulk is a deep learning-based algorithm that decodes alternative polyadenylation dynamics from bulk RNA-seq data.; Cell reports methods. 2024 Feb 03.
- ALS-Associated TDP-43 Dysfunction Compromises UPF1-Dependent mRNA Metabolism Pathways Including Alternative Polyadenylation and 3'UTR Length.; bioRxiv : the preprint server for biology. 2024 Feb 02.
- A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay.; PLoS genetics; Vol 20(1), pp. e1011146. 2024 Jan 31.
- FMRP-mediated spatial regulation of physiologic NMD targets in neuronal cells.; Genome biology; Vol 25(1), pp. 31. 2024 Jan 23.
- FAK and p130Cas modulate stiffness-mediated early transcription and cellular metabolism.; bioRxiv : the preprint server for biology. 2024 Jan 16.
- Pseudouridylation-mediated gene expression modulation.; The Biochemical journal; Vol 481(1), pp. 1-16. 2024 Jan 10.
- Verapamil mitigates chloride and calcium bi-channelopathy in a myotonic dystrophy mouse model.; The Journal of clinical investigation; Vol 134(1). 2024 Jan 02.
- Estimating RNA Secondary Structure Folding Free Energy Changes with efn2.; Methods in molecular biology (Clifton, N.J.); Vol 2726, pp. 1-13. 2024.
- Cardiomyocyte-Specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy.; Cells; Vol 13(1). 2023 Dec 22.
- Cardiomyocyte-specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy.; bioRxiv : the preprint server for biology. 2023 Sep 22.
- HEXIM1 is an Essential Transcription Regulator During Human Erythropoiesis.; Blood. 2023 Sep 22.
- A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay.; bioRxiv : the preprint server for biology. 2023 Sep 18.
- Putting a finger on histidine methylation.; Genes & development; Vol 37(15-16), pp. 675-677. 2023 Sep 06.
- DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters.; ACS synthetic biology. 2023 Sep 06.
- Two Decades of Arrayed Imaging Reflectometry for Sensitive, High-Throughput Biosensing.; Biosensors; Vol 13(9). 2023 Sep 05.
- Structure and function analysis of a type III preQ1-I riboswitch from E. coli reveals direct metabolite-sensing by the Shine-Dalgarno sequence.; The Journal of biological chemistry. 2023 Sep 01.
- LinearCoFold and LinearCoPartition: linear-time algorithms for secondary structure prediction of interacting RNA molecules.; Nucleic acids research. 2023 Aug 31.
- Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase.; bioRxiv : the preprint server for biology. 2023 Aug 30.
- History of S. aureus Skin Infection Significantly Associates with History of Eczema Herpeticum in Patients with Atopic Dermatitis.; Dermatology and therapy. 2023 Aug 24.
- FAM210A regulates mitochondrial translation and maintains cardiac mitochondrial homeostasis.; Cardiovascular research. 2023 Jul 31.
- Aerosol Jet Printing-Enabled Dual-Function Electrochemical and Colorimetric Biosensor for SARS-CoV-2 Detection.; Analytical chemistry. 2023 Jul 28.
- Genome-Wide DNA Changes Acquired by Candida albicans Caspofungin-Adapted Mutants.; Microorganisms; Vol 11(8). 2023 Jul 25.
- RNA target highlights in CASP15: Evaluation of predicted models by structure providers.; Proteins. 2023 Jul 19.
- Identifying novel radioprotective drugs via salivary gland tissue chip screening.; bioRxiv : the preprint server for biology. 2023 Jul 13.
- Genetic Determinants of Acinetobacter baumannii Serum-Associated Adaptive Efflux-Mediated Antibiotic Resistance.; Antibiotics (Basel, Switzerland); Vol 12(7). 2023 Jul 11.
- RNA Secondary Structure Analysis Using RNAstructure.; Current protocols; Vol 3(7), pp. e846. 2023 Jul.
- NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1.; Journal of neuro-oncology. 2023 Jun 30.
- RNA design via structure-aware multifrontier ensemble optimization.; Bioinformatics (Oxford, England); Vol 39(39 Suppl 1), pp. i563-i571. 2023 Jun 30.
- Comparing FRET Pairs that Report on Intersubunit Rotation in Bacterial Ribosomes.; Journal of molecular biology; Vol 435(15), pp. 168185. 2023 Jun 20.
- Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli.; Protein expression and purification; Vol 210, pp. 106322. 2023 Jun 15.
- Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy.; bioRxiv : the preprint server for biology. 2023 Jun 15.
- DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters.; bioRxiv : the preprint server for biology. 2023 Jun 08.
- Combinatorial chloride and calcium channelopathy in myotonic dystrophy.; bioRxiv : the preprint server for biology. 2023 Jun 01.
- Computational Resources for Molecular Biology 2023.; Journal of molecular biology. 2023 May 25.
- FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.; bioRxiv : the preprint server for biology. 2023 May 22.
- Comparing FRET pairs that report on intersubunit rotation in bacterial ribosomes.; bioRxiv : the preprint server for biology. 2023 May 09.
- Algorithm for Optimized mRNA Design Improves Stability and Immunogenicity.; Nature. 2023 May 02.
- In vivo secondary structural analysis of Influenza A virus genomic RNA.; Cellular and molecular life sciences : CMLS; Vol 80(5), pp. 136. 2023 May 02.
- RNA binding protein PRRC2B mediates translation of specific mRNAs and regulates cell cycle progression.; Nucleic acids research. 2023 May 01.
- Csx28 is a membrane pore that enhances CRISPR-Cas13b-dependent antiphage defense.; Science (New York, N.Y.); Vol 380(6643), pp. 410-415. 2023 Apr 27.
- Oncogenic CDK13 mutations impede nuclear RNA surveillance.; Science (New York, N.Y.); Vol 380(6642), pp. eabn7625. 2023 Apr 21.
- Generation and Functional Analysis of Defective Viral Genomes during SARS-CoV-2 Infection.; mBio. 2023 Apr 19.
- The Life and Times of a tRNA.; RNA (New York, N.Y.). 2023 Apr 13.
- Interplay between Inter-Subunit Rotation of the Ribosome and Binding of Translational GTPases.; International journal of molecular sciences; Vol 24(8). 2023 Apr 07.
- RNA in the loop: Probing T-loop/T-loop receptor interactions as mediators of long-range RNA contacts that influence gene regulation.; Journal of molecular biology. 2023 Apr 06.
- Bi-allelic variants in INTS11 are associated with a complex neurological disorder.; American journal of human genetics. 2023 Apr 04.
- Feature Papers in Optical Sensors 2022.; Sensors (Basel, Switzerland); Vol 23(7). 2023 Apr 03.
- Time-resolved cryo-EM of G protein activation by a GPCR.; bioRxiv : the preprint server for biology. 2023 Mar 21.
- Structures of Ric-8B in complex with Gα protein folding clients reveal isoform specificity mechanisms.; Structure (London, England : 1993); Vol 31(5), pp. 553-564.e7. 2023 Mar 16.
- Antisense oligonucleotide targeting DMPK in patients with myotonic dystrophy type 1: a multicentre, randomised, dose-escalation, placebo-controlled, phase 1/2a trial.; The Lancet. Neurology; Vol 22(3), pp. 218-228. 2023 Mar.
- Alternative polyadenylation alters protein dosage by switching between intronic and 3'UTR sites.; Science advances; Vol 9(7), pp. eade4814. 2023 Feb 17.
- Biosensing with Silicon Nitride Microring Resonators Integrated with an On-Chip Filter Bank Spectrometer.; ACS sensors. 2023 Feb 14.
- Methods special issue: RNA-targeting technologies.; Methods (San Diego, Calif.); Vol 212, pp. 10-11. 2023 Feb 13.
- A riboswitch separated from its ribosome-binding site still regulates translation.; Nucleic acids research. 2023 Feb 10.
- Arrayed Imaging Reflectometry monitoring of anti-viral antibody production throughout vaccination and breakthrough Covid-19.; PloS one; Vol 18(2), pp. e0277846. 2023 Feb 07.
- Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes.; Molecular cell. 2023 Feb 03.
- Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders.; Nature communications; Vol 14(1), pp. 583. 2023 Feb 03.
- New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity.; Nucleic acids research. 2023 Jan 30.
- Unveiling the RNA-mediated allosteric activation discloses functional hotspots in CRISPR-Cas13a.; Nucleic acids research. 2023 Jan 30.
- Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis.; Journal of cardiovascular development and disease; Vol 10(2). 2023 Jan 29.
- PolyAMiner-Bulk: A Machine Learning Based Bioinformatics Algorithm to Infer and Decode Alternative Polyadenylation Dynamics from bulk RNA-seq data.; bioRxiv : the preprint server for biology. 2023 Jan 24.
- Attitudes and experiences regarding preventive strategies for the deaf population in Western New York.; PLOS global public health; Vol 3(11), pp. e0001056. 2023 Jan 22.
- Coevolution combined with molecular dynamics simulations provides structural and mechanistic insights into the interactions between the integrator complex subunits.; Computational and structural biotechnology journal; Vol 21, pp. 5686-5697. 2023 Jan 19.
- PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII.; Molecular cell; Vol 83(2), pp. 186-202.e11. 2023 Jan 19.
- Gene, RNA, and ASO-based therapeutic approaches in Cystic Fibrosis.; Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 2023 Jan 17.
- The Integrator complex desensitizes cellular response to TGF-β/BMP signaling.; Cell reports; Vol 42(1), pp. 112007. 2023 Jan 14.
- Post-transcriptional control of the essential enzyme MurF by a small regulatory RNA in Brucella abortus.; Molecular microbiology. 2023 Jan 11.
- Full-Length NAD+-I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate.; Biochemistry. 2023 Jan 10.
- Photomodulation of the ASIC1a acidic pocket destabilizes the open state.; Protein science : a publication of the Protein Society. 2023 Jan 08.
- Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways.; American journal of hematology. 2023 Jan 06.
- Integrator is a global promoter-proximal termination complex.; Molecular cell. 2023 Jan 04.
- A photonic biosensor-integrated tissue chip platform for real-time sensing of lung epithelial inflammatory markers.; Lab on a chip. 2023 Jan 03.
- Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy.; Nature communications; Vol 14(1), pp. 6166. 2023 Jan 03.
- Isothermal Titration Calorimetry Analysis of a Cooperative Riboswitch Using an Interdependent-Sites Binding Model.; Methods in molecular biology (Clifton, N.J.); Vol 2568, pp. 53-73. 2023.
- Linear-Time Algorithms for RNA Structure Prediction.; Methods in molecular biology (Clifton, N.J.); Vol 2586, pp. 15-34. 2023.
- In Vitro Reconstitution of Pseudouridylation Catalyzed by Human Box H/ACA Ribonucleoprotein Particles.; Methods in molecular biology (Clifton, N.J.); Vol 2666, pp. 177-191. 2023.
- Structure determination of inactive-state GPCRs with a universal nanobody.; Nature structural & molecular biology; Vol 29(12), pp. 1188-1195. 2022 Nov 17.
- Inositol hexakisphosphate is required for Integrator function.; Nature communications; Vol 13(1), pp. 5742. 2022 Sep 30.
- Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma.; Cell reports; Vol 40(9), pp. 111253. 2022 Aug 30.
- Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells.; Molecular and cellular neurosciences. 2022 Aug 30.
- Optimization of specific RNA knockdown in mammalian cells with CRISPR-Cas13.; Methods (San Diego, Calif.). 2022 Aug 17.
- Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay path way in evolutionarily distant yeast species.; PLoS genetics; Vol 18(7), pp. e1010215. 2022 Jul 28.
- Milestones of progression in myotonic dystrophy type 1 and type 2.; Muscle & nerve. 2022 Jul 01.
- A UHM - ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.; The Journal of biological chemistry. 2022 Jun 30.
- Deep learning models for RNA secondary structure prediction (probably) do not generalise across families.; Bioinformatics (Oxford, England). 2022 Jun 24.
- Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs.; Molecular therapy. Nucleic acids; Vol 28. 2022 Jun 14.
- Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing.; eLife; Vol 11. 2022 Jun 13.
- FAM114A1 influences cardiac pathological remodeling by regulating angiotensin II signaling.; JCI insight. 2022 Jun 07.
- 3'UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension.; Matrix biology : journal of the International Society for Matrix Biology; Vol 111, pp. 53-75. 2022 Jun 04.
- AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay.; Molecular cell. 2022 Jun 03.
- Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis.; JCI insight; Vol 7(10). 2022 May 23.
- Benefits of aerobic exercise in myotonic dystrophy type 1.; The Journal of clinical investigation; Vol 132(10). 2022 May 16.
- A Test and Refinement of Folding Free Energy Nearest Neighbor Parameters for RNA Including N6-Methyladenosine.; Journal of molecular biology. 2022 May 16.
- Computational Resources for Molecular Biology 2022.; Journal of molecular biology. 2022 May 12.
- Lessons from the functional characterization of lncRNAs: introduction to mammalian genome special issue.; Mammalian genome : official journal of the International Mammalian Genome Society. 2022 May 09.
- Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.; Nucleic acids research. 2022 May 07.
- Nearest neighbor rules for RNA helix folding thermodynamics: improved end effects.; Nucleic acids research. 2022 May 07.