Hemostasis and Thrombosis Research
Research Overview
The Hemostasis and Thrombosis Research Lab (HTRL) is currently focusing on several basic research projects investigating the pathways of human disease, immune function, blood transfusions, and hemostasis and thrombosis disorders.
Clinical Trials
We are involved in several pharmaceutical clinical trials as well as point of care device studies and instrument validation. Topics of pharmaceutical research include anticoagulation drug reversal in emergency settings, transfusion of new blood products, and novel prophylactic drugs for patients with diagnoses such as sickle cell disease or pulmonary embolism.
We have conducted a range of different point of care device studies that have involved testing anything from INR levels to activated clot time to blood glucose.
Currently we are working on a new platform to validate several coagulation-related assays that could be used routinely in clinical laboratories in the future.
Volunteer Opportunities in the HTRL
We welcome students to inquire about our ongoing projects! Volunteers will gain hands-on experience in tasks such as data collection, literature reviews, and have the opportunity to collaborate with researchers and attend lab meetings.
Applicants must be current college students, preferably from the University of Rochester, with an interest in coagulation and blood banking. This is a great opportunity to build research skills, enhance your resume, and contribute to impactful projects.
Please email Dr. Refaai for more information.
Majed A. Refaai, M.D.
Principal Investigator
- Differences in outcomes associated with ABO blood groups in recipients of IVIG.; Blood vessels, thrombosis & hemostasis; Vol 2(3), pp. 100075. 2025 May 09.
- Eliminating leukocyte reduction for whole blood: Is it premature to consider this paradigm-changing practice?; Transfusion. 2024 Dec 22.
- ABO blood group, ABO mismatched transfusions and leukoreduction of transfusions in hemostatic resuscitation studies.; Frontiers in bioengineering and biotechnology; Vol 12, pp. 1437471. 2024 Sep 16.
- In response: ABO nonidentical platelet transfusions and mortality.; Transfusion; Vol 64(5), pp. 954-956. 2024 May.
Contact Us
Refaai Lab
601 Elmwood Ave, Box 608
Rochester, NY 14642
(585) 273-3002