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URMC / Alzheimers Care / Current Research Opportunities
 

Current Research Opportunities

ADMET – II

Apathy in Dementia Methylphenidate Trial 2

Sponsored by the National Institute on Aging (NIA), this research study examines the effectiveness of using an ADHD medication to improve cognition, interest, and emotion in those with Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=13&show_locs=Y

 

ADNI – 3

Federally-funded, ADNI (Alzheimer’s Disease Neuroimaging Initiative) examines historic brain aging through imaging, in the hopes of better understanding how Alzheimer’s Disease functions.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=7&show_locs=Y

 

ADNI – DoD

Sponsored by the Department of Defense, this research study examines brain aging in Vietnam War Veterans as it correlates to Traumatic Brain Injury (TBI) and Post-Traumatic Stress Disorder (PTSD) that may be associated with a greater risk of Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=14&show_locs=Y

 

AMARANTH & AMARANTH Extension

Sponsored by Eli Lilly & Company and AstraZeneca, this study assesses the efficacy and safety of an investigational medical treatment for early Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/NCT02245737?recrs=abdf&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=5

 

AVANIR – 301 & 303

Sponsored by AVANIR Pharmaceuticals, these studies evaluate an investigational medication that may reduce agitation in patients with dementia related to Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=9&show_locs=Y

https://clinicaltrials.gov/ct2/show/study/NCT02446132?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=1#locn

 

EARLY

Sponsored by Janssen Research & Development, this global research trial examines the safety and efficacy of an investigational medication in those with a familial connection to or at risk of developing Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=12&show_locs=Y

 

ENGAGE

Sponsored by Biogen Pharmaceuticals, this study determines the safety of an investigational medicine and its effectiveness on slowing the progression of early Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=5&show_locs=Y

 

GENE-MATCH

Sponsored by the National Institute of Aging (NIA) and part of the Alzheimer’s Prevention Registry, this program functions as a gateway to clinical trials by examining genetic information to determine which studies are most suitable for a specific participant.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=8&show_locs=Y

 

GENERATIONS 1 AND 2

Sponsored by Novartis Pharmaceuticals, this is an interventional study that evaluates the effectiveness of two medicinal therapies, administered separately, targeting those at risk of developing symptoms of Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=2

 

S-CitAD 

Funded by the National Institute on Aging (NIA), this study assesses investigational medical treatment, in addition to psychosocial intervention, as it correlates to agitation in Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study?recrs=ab&cond=Alzheimer+Disease&cntry=US&state=US%3ANY&city=Rochester&dist=50&rank=11&show_locs=Y

 

TANGO

Sponsored by Biogen Pharmaceuticals, this study evaluates the safety and tolerability of an investigational medicine in participants with mild to moderate Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/NCT03352557?term=tango&cond=Alzheimer+Disease&rank=2

 

TAURIEL

Sponsored by Genentech, a member of the Roche Group, this study assesses safety, tolerability, and efficacy of an experimental medication in people with early to mild signs of Alzheimer’s Disease.

https://clinicaltrials.gov/ct2/show/study/NCT03289143?term=genentech&cond=Alzheimer+Disease&rank=2&show_locs=Y#locn

 

For more information, or to sign up for a study, please visit: https://www.alz.org/research/clinical_trials/find_clinical_trials_trialmatch.asp

To sign up for GeneMatch: https://www.endalznow.org/genematch