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URochester Medicine / Department of Biostatistics and Computational Biology / People & Research / Faculty / Christopher Beck, PhD

Christopher Beck, PhD

Christopher BeckAssociate Professor of Biostatistics
Associate Professor of Orthopaedics
Associate Professor of Neurology
Associate Professor of Center for Health + Technology
Ph.D., University of Rochester

Contact Information

University of Rochester
Dept of Biostatistics and Computational Biology
265 Crittenden Boulevard, CU 420630 
Rochester, New York 14642-0630
 
Office: Saunders Research Building 4130
Phone: (585) 275-6781
E-mail: Christopher_Beck@urmc.rochester.edu

Research Interests

The area of statistical research that most interests me is the analysis of the performance of diagnostic tests.  Most of my work in this area involves inference concerning receiver operating characteristic (ROC) curves and surfaces.  I am actively developing statistical methods for ROC surfaces that generalize the methodology associated with ROC curves to accommodate the analysis of diagnostic tests that classify experimental units into three or more categories.  My other major research interests include change-point problems and clinical trials.

Most of my collaborative work is with researchers in the Department of Neurology and the Department of Orthopaedics and Rehabilitation, where I hold a joint appointment.  I am currently involved with studies in Parkinson's disease, Huntington's disease, Batten disease, periodic paralysis, orthopaedic trauma care, smoking cessation, and cardiomyopathy.  I am a member of an international team of researchers from several disciplines and universities that conducts studies to investigate the effects of neurotoxicants such as methyl mercury on the neurodevelopment of children.

I received a B.A. in Mathematics and Statistics and an M.A. in Statistics from State University of New York at Buffalo, and an M.A. and Ph.D. in Statistics from University of Rochester.  I am a member of the American Statistical Association and the International Biometric Society (ENAR).

Full List of Publications

A complete list of recent publications is available through my URMC Profile.

Selected Publications

  • Klose AM; Beck CA; Kates SL; Muthukrishnan G; Schwarz EM; Miller BL. "Dual-Scale StaphAIR: Predictive Modeling for the Diagnosis of Infection via Simultaneous Detection and Quantification of Cytokines and Antibodies." Analytical chemistry. 2026; Epub 2026 May 16.
  • Goldenberg I; Zareba W; Ezekowitz JA; Albert C; Alexis JD; Anderson L; Behr ER; Daubert J; Di Palo KE; Ellenbogen KA; Dzikowicz DJ; Harrington JM; Hsich E; Huang DT; Januzzi JL; Jawaid A; Kutyifa V; Lala-Trindade A; Nakonechnyi A; Onwuanyi A; Piña IL; Sandhu RK; Sears S; Sroubek J; Baykaner T; Strawderman R; Beck C; Butler J. "Rationale and design of the comparative effectiveness of ICD vs non-ICD therapy in contemporary heart failure patients at a low risk for arrhythmic death (CONTEMP-ICD) trial." American heart journal. 2026;291():162-174. 
  • Kates SL; Owen JR; Beck CA; Muthukrishnan G; Daiss JL; Golladay GJ. "Dilution of humoral immunity&#x3a&#x3b; Results from a natural history study of healthy total knee arthroplasty patients." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024;42(12):2835-2843
  • Krzowski B; Kutyifa V; Vloka M; Huang DT; Attari M; Aktas M; Shah AH; Musat D; Rosenthal L; McNitt S; Polonsky B; Schuger C; Natale A; Ziv O; Beck C; Daubert JP; Goldenberg I; Zareba W. "Sex-Related Differences in Ventricular Tachyarrhythmia Events in Patients With Implantable Cardioverter-Defibrillator and Prior Ventricular Tachyarrhythmias." JACC. Clinical electrophysiology. 2024;10(2):284-294
  • Anderson KE; Arbatti L; Hosamath A; Feigin A; Goldstein J; Kayson E; Kinsler BL; Falanga L; Denise L; Carlozzi NE; Frank S; Jackson K; Kostyk S; Purks JL; Serbin KP; Kinel S; Beck CA; Shoulson I. "What Huntington's Disease Patients Say About Their Illness: An Online Direct-to-Participant Pilot Study." Journal of Huntington's disease. 2024;13(2):237-248. 
  •  Campbell MP; Mott MD; Owen JR; Reznicek JE; Beck CA; Muthukrishnan G; Golladay GJ; Kates SL. "Low albumin level is more strongly associated with adverse outcomes and Staphylococcus aureus infection than hemoglobin A1C or smoking tobacco." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2022;40(11):2670-2677.
  • Younis A; Goldenberg I; Farooq S; Yavin H; Daubert J; Raitt M; Mazur A; Huang DT; Mitchell BL; Rashtian MR; Winters S; Vloka M; Aktas M; Bernabei MA; Beck CA; McNitt S; Zareba W. "Reduction in Ventricular Tachyarrhythmia Burden in Patients Enrolled in the RAID Trial." JACC. Clinical electrophysiology. 2022;8(6):754-762
  • Klose AM; Daiss JL; Ho L; Beck CA; Striemer CC; Muthukrishnan G; Miller BL. "StaphAIR: A Label-Free Antigen Microarray Approach to Detecting Anti- Antibody Responses in Orthopedic Infections." Analytical chemistry. 2021;93(40):13580-13588. 
  • Sulovari A; Ninomiya MJ; Beck CA; Ricciardi BF; Ketonis C; Mesfin A; Kaplan NB; Soin SP; McDowell SM; Mahmood B; Daiss JL; Schwarz EM; Oh I. "Clinical utilization of species-specific immunoassays for identification of Staphylococcus aureus and Streptococcus agalactiae in orthopedic infections." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2021;39(10):2141-2150.
  • Muthukrishnan G; Beck CA; Owen JR; Xie C; Kates SL; Daiss JL. "Serum antibodies against Staphylococcus aureus can prognose treatment success in patients with bone infections." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2021;39(10):2169-2176.
  • Heatwole C; Luebbe E; Rosero S; Eichinger K; Martens W; Hilbert J; Dekdebrun J; Dilek N; Zizzi C; Johnson N; Puwanant A; Tawil R; Schifitto G; Beck CA; Richeson JF; Zareba W; Thornton C; McDermott MP; Moxley R. "Mexiletine in Myotonic Dystrophy Type 1: A Randomized, Double-Blind, Placebo-Controlled Trial." Neurology. 2021;96(2):e228-e240.
  • Kates SL; Owen JR; Beck CA; Xie C; Muthukrishnan G; Daiss JL; Schwarz EM. "Lack of Humoral Immunity Against Glucosaminidase Is Associated with Postoperative Complications in Staphylococcus aureus Osteomyelitis." The Journal of bone and joint surgery. American volume. 2020;102(21):1842-1848
  • Beck CA; Beran DB; Biglan KM; Boyd CM; Dorsey ER; Schmidt PN; Simone R; Willis AW; Galifianakis NB; Katz M; Tanner CM; Dodenhoff K; Aldred J; Carter J; Fraser A; Jimenez-Shahed J; Hunter C; Spindler M; Reichwein S; Mari Z; Dunlop B; Morgan JC; McLane D; Hickey P; Gauger L; Richard IH; Mejia NI; Bwala G; Nance M; Shih LC; Singer C; Vargas-Parra S; Zadikoff C; Okon N; Feigin A; Ayan J; Vaughan C; Pahwa R; Dhall R; Hassan A; DeMello S; Riggare SS; Wicks P; Achey MA; Elson MJ; Goldenthal S; Keenan HT; Korn R; Schwarz H; Sharma S; Stevenson EA; Zhu W; . "National randomized controlled trial of virtual house calls for Parkinson disease." Neurology. 2017;89(11):1152-1161.
  • Moss AJ; Schuger C; Beck CA; Brown MW; Cannom DS; Daubert JP; Estes NA; Greenberg H; Hall WJ; Huang DT; Kautzner J; Klein H; McNitt S; Olshansky B; Shoda M; Wilber D; Zareba W; . "Reduction in inappropriate therapy and mortality through ICD programming." The New England journal of medicine. 2012;367(24):2275-83.
  • Dorsey ER; de Roulet J; Thompson JP; Reminick JI; Thai A; White-Stellato Z; Beck CA; George BP; Moses H. "Funding of US biomedical research, 2003-2008." JAMA. 2010;303(2):137-43. 

Last updated: October 23,  2026