Skip to main content

Hongmei Yang, PhD

Hongmei.YangResearch Associate Professor
Ph.D. (2007) North Carolina State University

Contact Information

University of Rochester
Dept of Biostatistics and Computational Biology
265 Crittenden Boulevard, CU 420630 
Rochester, New York 14642-0630
Office: Saunders Research Building 4148
Phone: (585) 275-0411
Fax: (585) 273-1031

Research Interests

My research is practically driven, a combination of active collaborations in HIV, Influenza, and other diseases and independent research. In summary it falls in three areas: statistical processing of assay data (e.g., Elispot, Elisa, and Hemagglutination assays), mixed-effect models for correlated data, and variable selection for high dimensional data.

Full List of Publications

Please visit my URMC Profile for a complete list of publications.

Selected Publications

  • Zhang, H., Yang, H., Bandyopadhyay, S., Milano, M.T., Fung, C., Messing, E.M. and Chen, Y. (2022) Increased Risk of High-Grade Prostate Cancer Among Testicular Cancer Survivors. PLOS ONE PMID: 35157714
  • Zhang, H., Doucette, C., Yang, H., Bandyopadhyay, S., Grossman, C.E., Jean-Gilles, J., Messing, E.M. and Chen, Y. (2021) Risk of adverse pathological features for intermediate risk prostate cancer: clinical implication for definitive radiation therapy. PLOS ONE. PMID: 34264975.
  • Phuong, N.C., Emo, K.L., Buckley, P.M., Reilly, N.S., Chaves, F.A., Yang, H., Oakes, P.W., Topham, D.J. (2020) S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit. mBio PMID: 32978311
  • Lartey, M., Kenu, E., Lassey, A., Ntumy, M., Ganu, V., Sam, M., Boamah, I., Gilani, F., Yang, H., Burch, G., Norman, J., Peloquin, C.A. and Kwara, A.,(2020) Pharmacokinetics of Efavirenz 600 mg Once daily during Pregnancy and Postpartum in Ghanaian Women Living with Human Immunodeficiency Virus. Clinical Therapeutics PMID: 32811669
  • Anderson, C.S., Sangster, M., Yang, H., Mariani, T.J., Chaudhury, S., Topham, D.J. (2020) Implementing Sequence-Based Antigenic Distance Calculation into Immunological Shape Space Model. BMC Bioinformatics PMID: 32560624
  • Reilly, E.C., Emo, K.L., Buckley, P.M., Reilly, N.S., Chaves, F.A., Yang, H., Oakes, P.W., Topham, D.J. (2020) TRM Integrins CD103 and CD49a Differentially Support Adherence and Motility After Resolution of Influenza Virus Infection. PNAS PMID: 32439709
  • Milano, M.T., Dinh, P., Yang, H., Zaid, M.A., Fossa, S.D., Feldman, D.R., Monahan, P.O., Travis, L.B. and Fung, C. (2020) Second Solid and Hematologic Neoplasms After Testicular Cancer: A U.S. Population-based Study of 24,900 Survivors. Journal of Clinical Oncology. PMID: 32455335.
  • Enimil, A., Antwi, S., Yang, H., Dompreh, A., Alghamdi, W., Gillani, F., Orstin, A., Bosomtwe, D., Opoku, T., Norman, J., WIESNER, L., Langaee, T., Peloquin, C.A., Court, M., Greenblatt, D. and Kwara, A., (2019) Effect of first-line antituberculosis therapy on nevirapine pharmacokinetics in children younger than 3 years old. Journal of Antimicrobial Chemotherapy PMID: 31332062.
  • Alghamdi, W., Antwi, S., Enimil, A., Yang, H., Dompreh, A., WIESNER, L., Langaee, T., Peloquin, C.A. and Kwara, A., (2019) Population Pharmacokinetics of Efavirenz in HIV and TB/HIV Coinfected Children: The Significance of Genotype-Guided Dosing. Journal of Antimicrobial Chemotherapy PMID: 31888865.
  • Kwara, A., Yang, H., Antwi, S., Enimil, A., Gillani, F.S., Dompreh, A., Ortsin, A., Opoku, T., Bosomtwe, D., Sarfo, M., WIESNER, L., Norman, J.,Alghamdi, W., Langaee, T., Peloquin, C.A., Court, M. and Greenblatt, D. (2018) Effect of rifampin/isoniazid-containing antituberculosis therapy on efavirenz pharmacokinetics in HIV-infected children aged 3 to 14 years old. Antimicrobial Agents and Chemotherapy PMID: 30397066
  • Anderson, C.S., McCall, P.R, Stern, H.A., Yang, H., Topham, D.J. (2018) Antigenic Cartography of H1N1 Influenza Viruses Using Sequence-Based Antigenic Distance Calculation. BMC Bioinformatics PMID: 29433425
  • Yang, H., Enimil, A., Gillani, F.S., Antwi, S., Dompreh, A., Ortsin, A., Awhireng, E.A., Owusu, M., WIESNER, L., Peloquin, C.A., and Kwara, A. (2018) Evaluation of the Adequacy of the 2010 Revised World Health Organization Recommended Dosages of the First-line Antituberculosis Drugs for Children: Adequacy of Revised Dosages of TB Drugs for Children. Pediatric Infectious Disease PMID: 28719501
  • Yang, H., Holden-Wiltse, J., Topham, D.J., Treanor, J., "Maximum Likelihood Estimation of Titer via a Power Family of Four-Parameter Logistic Model. Journal of Biopharmaceutical Statistics.. 2018 28(3):492-500. Epub 2017 Sept 05
  • Yang, H., Baker, S.F., González, M.E., Topham, D.J., Martínez-Sobrido, L., Zand, M., Holden-Wiltse, J. and Wu, H. (2015) An Improved Method for Estimating Antibody Titers in Microneutralization Assay Using Green Fluorescent Protein. Journal of Biopharmaceutical Statistics PMID: 26010892.
  • Yang H; Topham DJ; Holden-Wiltse J; Wu H "Statistical estimation & inference of cell counts from ELISPOT limiting dilution assays." Journal of biopharmaceutical statistics. 2013; 23(4):921-36.

Last updated: March 25, 2022