Services
Services
Assay Development and Optimization
- Assay development and optimization
- i.e., cell density, treatment time, anchor drug concentration
- Miniaturization to 384 wells
- Automation of existing assays
- Z′ factor (signal-to-background evaluation)
High-Throughput Screening
- Compound screening
- Dose-response screening
- Phenotypic screening
- Target-based screening
- Replication/validation screens
- Custom screening campaigns
Automated Research Services
- Automated liquid handling
- Automated cell seeding
- Reagent dispensing
- Serial dilutions
- Plate washing
- Automated plate reading
- High-content imaging
- Custom automation workflows
Data & Analysis
- Screening QC
- Hit identification
- Dose-response analysis
- Screening data interpretation
Consultation & Collaboration
- Experimental design
- Screening strategy
- Instrument selection
- Assay design
- Troubleshooting
- Grant Support
- Preliminary data generation
Researchers can access individual instruments for their own projects.
- Automated liquid handling
- Liquid dispensing
- Plate washing
- High-content imaging and reading of plates
Model 1: Instrument Access
Independent use of available instrumentation following appropriate training (except the Janus Liquid Handler and Zephyr)
Model 2: Assisted Projects
Staff-assisted instrument use, assay setup, optimization, and technical support.
Model 3: Full-Service Screening
Start-to-end screening services including assay development, automated screening, data processing, and analysis.
Fees: The HTS-SR provides tailored support based on the specific needs of each screening project. Pricing may vary depending on the scope of the project, assay requirements, screening strategy, and level of technical support required. Please contact the HTS-SR Director (link to email), for a project-based estimate.