Influenza Hospitalization Surveillance
Purpose
Active surveillance for hospitalized laboratory–confirmed influenza cases among Rochester area residents has been conducted since 2004. Laboratory-confirmed influenza is reportable to the New York State Department of Public Health; EIP staff collect data to determine underlying conditions, influenza testing patterns, and markers of disease severity.
Goals and Objectives
- Determine the age-specific rates of laboratory confirmed influenza associated hospitalization.
- Determine the rate of serious influenza-associated complications, such as secondary bacterial infections, and the need for ICU admission/mechanical ventilation.
- Identify factors that are associated with severe illness or influenza-associated complications.
- Evaluate adherence to influenza vaccination recommendations.
Activities
Active surveillance for laboratory-confirmed influenza hospitalizations is conducted among residents of the seven county Rochester catchment area. A case is defined as a resident in the catchment area having a hospital admission with a laboratory confirmed influenza infection. Demographic, diagnostic, medical and vaccination histories are collected from the medical charts of cases and are recorded on a standardized case report form.
Comprehensive and aggregate data analyses for this project are ongoing and available at the following websites:
Data
The incidence of influenza hospitalizations varies each season and by age group, depending on what strain of influenza is most prominent and the efficacy of the vaccine.
Selected Publications
- Collins JP, Campbell AP, Openo K, Farley MM, Cummings CN, Kirley PD, Herlihy R, Yousey-Hindes K, Monroe ML, Ladisky M, Lynfield R, Baumbach J, Spina N, Bennett N, Billing L, Thomas A, Schaffner W, Price A, Garg S, Anderson EJ. Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011-2015. J Pediatric Infec Dis Soc. 2018 Oct 25. doi: 10.1093/jpids/piy101
- Chandrasekhar R, Sloan C, Mitchel E, Ndi D, Alden N, Thomas A, Bennett NM, Kirley PD, Hill M, Anderson EJ, Lynfield R, Yousey-Hindes K, Bargsten M, Zansky SM, Lung K, Schroeder M, Monroe M, Eckel S, Markus TM, Cummings CN, Garg S, Schaffner W, Lindegren ML. Social determinants of influenza hospitalization in the United States. Influenza Other Res Viruses. 2017 Nov;11(6):479-488. doi: 10.1111/irv.12483.
- Arriola CS, Garg S, Anderson EJ, Ryan PA, George A, Zansky SM, Bennett N, Reingold A, Bargsten M, Miller L, Yousey-Hindes K, Tatham L, Bohm SR, Lynfield R, Thomas A, Lindegren ML, Schaffner W, Fry AM, Chaves SS. Influenza vaccination modifies disease severity among community-dwelling adults hospitalized with influenza. Clin Infect Dis. 2017 May 19. doi: 10.1093/cid/cix468.
- Appiah GD, Chaves SS, Kirley PD, Miller L, Meek J, Anderson E, Oni O, Ryan P, Eckel S, Lynfield R, Bargsten M, Zansky SM, Bennett N, Lung K, McDonald-Hamm C, Thomas A, Brady D, Lindegren ML, Schaffner W, Hill M, Garg S, Fry AM, Campbell AP. Increased antiviral treatment among hospitalized children and adults with laboratory-confirmed influenza, 2010-2015. Clin Infect Dis. 2017 Feb 1;64(3):364-367.
- Havers F, Sokolow L, Shay DK, Farley MM, Monroe M, Meek J, Daily Kirley P, Bennett NM, Morin C, Aragon D, Thomas A, Schaffner W, Zansky SM, Baumbach J, Ferdinands J, Fry AM. Case-control study of vaccine effectiveness in preventing laboratory-confirmed influenza hospitalizations in older adults, United States, 2010-2011. Clin Infect Dis. 2016 Nov 15;63(10):1304-1311.