Glomerulonephritis
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What is Glomerulonephritis?
Glomerulonephritis is a condition in which the tiny filters in the kidneys, called glomeruli, become inflamed or scarred. These filters normally remove waste and extra fluid from the blood to make urine. When they are damaged, the kidneys cannot work as well over time. There are many possible causes, including autoimmune diseases such as lupus and blood vessel diseases like granulomatosis with polyangiitis, among others.
Warning Signs of Glomerulonephritis
Glomerulonephritis is difficult to detect. In the early stages, you may have no symptoms at all. As the disease progresses, these warning signs may appear:
- High blood pressure
- Excessive foaming of the urine
- Red or dark brown urine
- Puffiness of the eyes, hands and feet
- Nausea and vomiting
- Difficulty breathing
Diagnosing Glomerulonephritis
A urine test can help show whether you might have glomerulonephritis. This test looks for protein and red blood cells in your urine, which can be early signs of kidney inflammation.
Your nephrologist may also order blood tests to measure the amount of waste products or the level of various types of antibodies in your blood.
If your doctor suspects glomerulonephritis, they may recommend a kidney biopsy. During this procedure, a small sample of kidney tissue is taken and examined under a microscope to determine the cause and guide treatment.
Learn More about Glomerulonephritis
Glomerulonephritis, Causes, Signs and Symptoms, Diagnosis and Treatment - Video
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Call (585) 275-4517Treatments for Glomerulonephritis
Glomerulonephritis can be serious and may lead to long-term kidney damage if not treated promptly. Early evaluation and treatment are important to slow or prevent the progression of kidney disease.
In some mild cases, your kidneys may recover on their own.
For many patients, the progression of glomerulonephritis can be slowed by lowering your blood pressure with medication and making changes to your diet.
Other treatments options may include:
- Steroids to decrease inflammation and scar tissue formation
- Diuretics (water pills) to help remove extra fluid from the body
- Immunosuppressive medications, including some chemotherapy drugs, to reduce immune system activity to prevent further kidney damage
Sometimes patients may need dialysis treatments to clean their blood while other therapies are being started. If kidney damage becomes severe and the kidneys can no longer perform their usual functions, long-term dialysis or kidney transplant may be needed. It’s crucial to establish care with a nephrologist promptly, as early intervention can improve kidney function and reduce the risk of disease progression.
For questions about your diagnosis, treatment options, or what these findings mean for your health, please speak with your nephrologist at your next visit or contact your kidney care team through MyChart. They can provide personalized guidance based on your specific condition.
What Sets Us Apart?
U.S. News & World Reports has identified us as one of the top adult nephrology (kidney) care centers in the country.
Our collaborative approach brings a wide range of expertise and different perspectives to patient care, with specialists in cardiology, endocrinology, rheumatology, transplant surgery, and urology working together to develop the best treatments for each patient.
Because we’re an academic medical center, our physicians also lead important research studies, with significant grants from the National Institutes of Health and industry-sponsored clinical trials.
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