Treatment of Myotonic Dystrophy Mouse Models with Calcium Channel Blockers and Anti-myotonics

Advisor: John Lueck, Ph.D.

Now: Postdoctoral Fellow at University of Rochester, Rochester NY

Electroporation-mediated Gene Delivery of CFTR Plasmids as a Novel Approach to Treat Cystic Fibrosis in vivo

Advisor: David Dean, Ph.D.

Functional Role of Orphan G Protein-coupled Receptor GPRC5B in Retinoic Acid Induced Depressive-like Behaviors and Adult Hippocampal Neurogenesis

Advisor: Cesare Orlandi, Ph.D.

Now: Postdoctoral Fellow at Tulane University, New Orleans, LA

Characterization of KCNE6 and KCNE7: Novel Regulators of Cardiac Repolarization Channels KCNQ1 and hERG

Advisor: Douglas Anderson, Ph.D.

Immune Regulatory Role of Platelets: Platelets Maintain Monocyte Immune Homeostasis

Advisor: Craig Morrell, D.V.M., Ph.D.

Now: Scientist II at Nona Bioscience, Natick, MA

Platelet Regulation of Monocyte and Macrophage Activation Status

Advisor: Craig Morrell, D.V.M., Ph.D.

Now: Research Technician II at University of Rochester, Rochester, NY

Histidine in the pH Modulatory Activity of the Principal Enamel Protein Amelogenin

Advisor: Thomas Diekwisch, D.M.D., Ph.D., Ph.D.

Impact of Oxidative Stress on Inflammation and Pain Hypersensitivity in Localized Provoked Vulvodynia

Advisor: Megan Falsetta, Ph.D.

Development of ACE-tRNAs as a Platform Therapeutic for Cystic Fibrosis

Advisor: John Lueck, Ph.D.

Efferocytosis of Apoptotic Neutrophils by Mesenchymal Stem/Stromal Cells

Advisor: Roman Eliseev, M.D., Ph.D.

Now: Pharmacy Technician at Wegmans, Rochester, NY

Alteration of Muscle Contractility, Mitochondrial Function, and Calcium Handling in a novel Orai1 Tubular Aggregate Myopathy Mouse Model and the Restorative Impact of Endurance Exercise

Advisor: Robert Dirksen, Ph.D.

Now: Postdoctoral Fellow at UC Davis Health, Davis, CA

Molecular Mechanisms Regulating G Protein Signaling Bias

Advisor: Cesare Orlandi, Ph.D.

Now: Assistant Professor at Taif University, Ta’if Saudi Arabia

Dysregulated Ca2+ Signaling, Fluid Secretion, and Mitochondrial Function in a Mouse Model of Early Sjögren’s Syndrome

Advisor: David Yule, Ph.D.

Now: Postdoctoral Fellow at University of Pittsburgh, Pittsburgh, PA

Exercise-induced Piezo1 and Piezo2 Upregulation and Chondroprotection Against Mechanical Injury

Advisor: Whasil Lee, Ph.D.

Now: Predoctoral Student at Cellular and Molecular Pharmacology and Physiology Program at University of Rochester, Rochester, NY

Anticodon Engineered Transfer RNA as a Potential Therapeutic for Nonsense Mutation-Associated Cystic Fibrosis

Advisor: John Lueck, Ph.D.

Now: Research Specialist at Integrated Pharmacology, Vertex Pharmaceuticals, Boston, MA

An Optimized Method for the Development of a Synthetic Yeast Displayed Nanobody Library

Advisor: John Lueck, Ph.D.

Now: Research Specialist II at University of Rochester, Rochester, NY

Inhibition of Kmt5a in C2C12 Cells Leads to Dysregulation of Iron Metabolism, Causing Cell Death through Ferroptosis

Advisor: Robert Dirksen, Ph.D.

Now: Predoctoral Student at Pathology at Cell Biology of Disease Program at University of Rochester, Rochester, NY

Isolating the Role of Myotonia in Myotonic Dystrophy Type 1 Pathogenesis Through a Novel Myotonia Resistant Mouse Model

Advisor: John Lueck, Ph.D.

Now: Medical Scientist Training Program at University of Rochester, Rochester, NY

Insights into Roles of Aging and Chemokine Signaling During Neuromuscular Regeneration

Advisor: Joe Chakkalakal, Ph.D.

The Role of HspB8 In Maintaining tau Proteostasis

Advisor: Gail Johnson, Ph.D

Redefining the Function of Salivary Duct Cell Populations Utilizing a Structural, Functional, and Computational Approach

Advisor: David Yule, Ph.D.

Now: Technical Specialist at Troutman Pepper Law Firm, Rochester, NY

Investigating Hydrogen Sulfide as a Regulator of Mitochondrial Complex II Reversal in Cardiac Ischemia

Advisor: Paul Brookes, Ph.D.

The Future is Female: A Look at Fracture Therapeutics for Female Athletes

Now: Medical Student at Medical College of Georgia, Augusta, GA

Topography and Motion of the Acid-sensing Ion Channel 1 Intracellular Domains”

Advisor: David MacLean, Ph.D.

Genetic Mutations of ECM Components Resulting in Heritable Connective Tissue Disorders

Electroporation Mediated Gene Delivery to Rescue the Alveolar Capillary Barrier Function for ARDS Treatment

Advisor: David MacLean, Ph.D.

Now: Postdoctoral Fellow at University of Pennsylvania, Philadelphia, PA

A Comprehensive Overview of Metabotropic Glutamate Receptor Dimer Signaling

Advisor: Paul Kammermeier, Ph.D.

Now: Postdoctoral Fellow at University of Rochester, Rochester, NY

Investigating Succinate and pH Dynamics in Cardiac Ischemia-Reperfusion Injury

Advisor: Paul Brookes, Ph.D.

Now: Scientific Communications Manager at AlphaGroup Medical Communications, Rochester NY

KRIT1-mediated regulation of the cellular response to inflammation

Advisor: Angela Glading, Ph.D.

Now: Senior Scientist at Frontage Laboratories, Inc., Downington, PA

Optical Interrogation of Acid-Sensing Ion Channel Gating Mechanisms

Advisor: David MacLean, Ph.D.

Now: Scientist at Atalanta Therapeutics, Cambridge, MA

Methamphetamine abuse and the risk of Alzheimer’s Disease

Advisor: Gail Johnson, Ph.D

Now: MSTP Program at MD Anderson Cancer Center, UTHealth, Houston TX

Differential Regulation of Opioid Receptor Signaling via Gα Proteins

Advisor: Jean Bidlack, Ph.D.

Now: Clinical Scientist at Myeloid Therapeutics at Biogen, Cambridge, MA

Regulation, Function and Mechanism of Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction

Advisor: Chen Yan, Ph.D.

Now: Postdoctoral Fellow at University of Rochester, Rochester, NY

FGF21 Reduced Morphine Preference and the Development of Acute Antinociceptive Tolerance and Physical Dependence

Advisor: Jean Bidlack, Ph.D.

Now: Preclinical Scientist at Akero Therapeutics Inc., Boston, MA

Advisor: Angela Glading, Ph.D.

Now: Research Scientist at Vertex Pharmaceuticals, Boston, MA

Functional Analysis of Disease-associated Mutations in the Inositol 1,4,5-Trisphosphate Receptor

Advisor: David Yule, Ph.D.

Now: Postdoctoral IRTA Trainee (Intramural Research Training Award) at NIH-NIDCR, Bethseda, MA

Cyclic Nucleotide Phosphodiesterase and Abdominal Aortic Aneurysm

Now: Postdoctoral Fellow at Stanford University, Stanford, CA