Lab Members

Molecular mechanisms of Neurodegeneration

The molecular mechanisms of tau clearance by autophagy and endocytosis using mammalian model sytems (primary neurons and mice)

Using pharmaco-genetics, fluorescent biosensor imaging, and proximity labeling to unravel the molecular mechanism through which pTau impairs mitophagy

The molecular mechanisms of pathological tau-induced mitochondrial dysfunction

The effects of pathological tau uptake by astrocytes on mitochondrial function and the impact on their ability to support neuron health

Tau Post-Translational Modifications mediate cellular dysfunctions in Alzheimer’s Disease

Transglutaminase 2 Deletion Attenuates Chronic Pathology Following Repetitive Mild Traumatic Brain Injury in Association with Enhanced Astrocyte-to-Neuron Metabolic Support

The effect of mitochondrial dysfunction and oxidative stress on tau pathology.

The relationship between tau pathology and mitochondrial dysfunction as regulated by BAG3