URochester Medicine / Labs / Garcia-Hernandez Lab / Publications

Publications

1. Liu T
2. Miller LM
3. Dresden BP
4. Zhao C
5. Pillai Y
6. Rangel-Garcia A
7. Garcia-Hernandez ML
8. Rangel-Moreno J
9. Chen W
10. Alcorn JF
Influenza virus and Staphylococcus aureus super-infection disrupts spatially coordinated cellular immunity in the mouse lung.; Communications biology. 2025 Nov 23.
1. Yang H
2. Kumaran VR
3. Song K
4. Remcho TP
5. Clark RDE
6. Thakur S
7. Lu S
8. Harrison MAA
9. Iwanaga N
10. Garcia-Hernandez ML
11. Rangel-Moreno J
12. Zwezdaryk KJ
13. McCombs JE
14. Norton EB
15. Kolls JK
Glycolysis maintains effector function of lung Th17 TRM cells in precision cut lung slices.; iScience; Vol 28(12), pp. 114051. 2025 Nov 14.
1. DeVito L
2. Mohanraj OS
3. Debnath D
4. Constantinesco NJ
5. Chinnappan B
6. Srikanth S
7. Moras C
8. Marinelli MA
9. Richwalls LJ
10. Ramasubramanian V
11. Carver C
12. Ramaswami B
13. Garcia-Hernandez ML
14. Rangel-Moreno J
15. Alcorn JF
16. Gopal R
Influenza infection exacerbates high-fat diet-induced atherosclerosis in apolipoprotein gene-deficient mice.; Journal of immunology (Baltimore, Md. : 1950). 2025 Oct 30.
1. Garcia-Hernandez ML
2. Rangel-Moreno J
3. Xu Q
4. Jeong YJ
5. Bhattacharya S
6. Misra R
7. Duemmel S
8. Yuan K
9. Korman BD
TNF drives aberrant BMP signaling to induce endothelial and mesenchymal dysregulation in pulmonary hypertension.; JCI insight. 2025 Jun 26.
1. Garcia-Hernandez ML
2. Ritchlin CT
3. Guy DR
4. Wechalekar M
New Insights into the Pathogenesis of Psoriatic Arthritis.; Rheumatic diseases clinics of North America; Vol 51(3), pp. 397-415. 2025 Jun 11.
1. Gopal R
2. Marinelli MA
3. Rago F
4. Richwalls LJ
5. Constantinesco NJ
6. Debnath D
7. Kupul S
8. Garcia-Hernandez ML
9. Rangel-Moreno J
10. Kolls JK
11. Alcorn JF
CD209d/e promotes inflammation and lung injury during influenza virus infection.; ImmunoHorizons; Vol 9(1). 2025 Jan 23.
1. Nogales A
2. Chiem K
3. Lorenzo MM
4. Rangel-Moreno J
5. de la Luz Garcia-Hernandez M
6. Park JG
7. Blasco R
8. Martinez-Sobrido L
Evaluation of Vaccinia Virus Infection in Mice Using Two-Reporter Recombinant Virus.; Methods in molecular biology (Clifton, N.J.); Vol 2860, pp. 157-174. 2025.
1. Van Buren E
2. Azzara D
3. Rangel-Moreno J
4. Garcia-Hernandez ML
5. Murphy SP
6. Cohen ED
7. Lewis E
8. Lin X
9. Park HR
Single-cell RNA sequencing reveals placental response under environmental stress.; Nature communications; Vol 15(1), pp. 6549. 2024 Aug 02.
1. Ritchlin CT
2. Rangel-Moreno J
3. Martino D
4. Isett B
5. Paine A
6. Bhattacharya S
7. Fox J
8. Meyer EM
9. Bao R
10. Bruno T
11. Tausk F
12. de la Luz Garcia-Hernandez M
Psoriatic arthritis subtypes are phenocopied in humanized mice.; JCI insight; Vol 9(15). 2024 Jul 02.
1. Furuya H
2. Nguyen CT
3. Chan T
4. Marusina AI
5. Merleev AA
6. Garcia-Hernandez ML
7. Hsieh SL
8. Tsokos GC
9. Ritchlin CT
10. Tagkopoulos I
11. Maverakis E
12. Adamopoulos IE
IL-23 induces CLEC5A+ IL-17A+ neutrophils and elicit skin inflammation associated with psoriatic arthritis.; Journal of autoimmunity; Vol 143, pp. 103167. 2024 Jan 31.
1. Constantinesco NJ
2. Chinnappan B
3. DeVito LJ
4. Moras C
5. Srikanth S
6. Garcia-Hernandez ML
7. Rangel-Moreno J
8. Gopal R
Sodium-Glucose Cotransporter-2 Inhibitor, Empagliflozin, Suppresses the Inflammatory Immune Response to Influenza Infection.; ImmunoHorizons; Vol 7(12), pp. 861-871. 2023 Dec 01.
1. Castillo RL
2. Sidhu I
3. Dolgalev I
4. Chu T
5. Prystupa A
6. Subudhi I
7. Yan D
8. Konieczny P
9. Hsieh B
10. Haberman RH
11. Selvaraj S
12. Shiomi T
13. Medina R
14. Girija PV
15. Heguy A
16. Loomis CA
17. Chiriboga L
18. Ritchlin C
19. Garcia-Hernandez ML
20. Carucci J
21. Meehan SA
22. Neimann AL
23. Gudjonsson JE
24. Scher JU
25. Naik S
Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems.; Science immunology; Vol 8(84), pp. eabq7991. 2023 Jun 02.
1. Quijada P
2. Park S
3. Zhao P
4. Kolluri KS
5. Wong D
6. Shih KD
7. Fang K
8. Pezhouman A
9. Wang L
10. Daraei A
11. Tran MD
12. Rathbun EM
13. Burgos Villar KN
14. Garcia-Hernandez ML
15. Pham TT
16. Lowenstein CJ
17. Iruela-Arispe ML
18. Carmichael ST
19. Small EM
20. Ardehali R
Cardiac pericytes mediate the remodeling response to myocardial infarction.; The Journal of clinical investigation; Vol 133(10). 2023 May 15.
1. Swanson RV
2. Gupta A
3. Foreman TW
4. Lu L
5. Choreno-Parra JA
6. Mbandi SK
7. Rosa BA
8. Akter S
9. Das S
10. Ahmed M
11. Garcia-Hernandez ML
12. Singh DK
13. Esaulova E
14. Artyomov MN
15. Gommerman J
16. Mehra S
17. Zuniga J
18. Mitreva M
19. Scriba TJ
20. Rangel-Moreno J
21. Kaushal D
22. Khader SA
Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.; Nature immunology. 2023 Apr 03.
1. Paine A
2. Brookes PS
3. Bhattacharya S
4. Li D
5. Garcia-Hernandez ML
6. Tausk F
7. Ritchlin C
Dysregulation of bile acids, lipids, and nucleotides in psoriatic arthritis revealed by unbiased profiling of serum metabolites.; Arthritis & rheumatology (Hoboken, N.J.). 2022 Jul 11.
1. Garcia-Hernandez MA
2. Ritchlin CT
New Tech Provides Insights into the Pathogenesis of Psoriatic Arthritis; The Rheumatologist. 2022 Jan 01.
1. Rangel-Moreno J
2. Garcia-Hernandez ML
3. Owen T
4. Barnard J
5. Becerril-Villanueva E
6. Kashyap T
7. Argueta C
8. Gamboa-Dominguez A
9. Tamir S
10. Landesman Y
11. Goldman BI
12. Ritchlin CT
13. Anolik JH
Small molecule inhibitors of nuclear export ameliorate lupus by modulating plasma cell generation and survival.; Arthritis & rheumatology (Hoboken, N.J.). 2022 Mar 25.
1. Garcia-Hernandez ML
2. Rangel-Moreno J
3. Garcia-Castaneda M
4. Kenney HM
5. Paine A
6. Thullen M
7. Anandarajah AP
8. Schwarz EM
9. Dirksen RT
10. Ritchlin CT
Dendritic cell-specific transmembrane protein is required for synovitis and bone resorption in inflammatory arthritis.; Frontiers in immunology; Vol 13, pp. 1026574. 2022 Jan 07.
1. Chiem K
2. Lorenzo MM
3. Rangel-Moreno J
4. Garcia-Hernandez ML
5. Park JG
6. Nogales A
7. Blasco R
8. Martínez-Sobrido L
Bi-Reporter Vaccinia Virus for Tracking Viral Infections In Vitro and In Vivo.; Microbiology spectrum. 2021 Nov 24.
1. Esaulova E
2. Das S
3. Singh DK
4. Choreño-Parra JA
5. Swain A
6. Arthur L
7. Rangel-Moreno J
8. Ahmed M
9. Singh B
10. Gupta A
11. Fernández-López LA
12. de la Luz Garcia-Hernandez M
13. Bucsan A
14. Moodley C
15. Mehra S
16. García-Latorre E
17. Zuniga J
18. Atkinson J
19. Kaushal D
20. Artyomov MN
21. Khader SA
The immune landscape in tuberculosis reveals populations linked to disease and latency.; Cell host & microbe. 2020 Dec 16.
1. Bell RD
2. White RJ
3. Garcia-Hernandez ML
4. Wu E
5. Rahimi H
6. Marangoni RG
7. Slattery P
8. Duemmel S
9. Nuzzo M
10. Huertas N
11. Yee M
12. O'Reilly MA
13. Morrell C
14. Ritchlin CT
15. Schwarz EM
16. Korman BD
TNF Induces Obliterative Pulmonary Vascular Disease in a Novel Model of Connective Tissue Disease Associated Pulmonary Arterial Hypertension (CTD-PAH).; Arthritis & rheumatology (Hoboken, N.J.). 2020 May 10.
1. Taya M
2. Garcia-Hernandez M
3. Rangel-Moreno J
4. Minor B
5. Gibbons E
6. Hammes SR
Neutrophil elastase from myeloid cells promotes TSC2-null tumor growth.; Endocrine-related cancer. 2020 Feb 01.
1. Hwang JY
2. Silva-Sanchez A
3. Carragher DM
4. Garcia-Hernandez ML
5. Rangel-Moreno J
6. Randall TD
Inducible Bronchus-Associated Lymphoid Tissue (iBALT) Attenuates Pulmonary Pathology in a Mouse Model of Allergic Airway Disease.; Frontiers in immunology; Vol 11. 2020.
1. Ardain A
2. Domingo-Gonzalez R
3. Das S
4. Kazer SW
5. Howard NC
6. Singh A
7. Ahmed M
8. Nhamoyebonde S
9. Rangel-Moreno J
10. Ogongo P
11. Lu L
12. Ramsuran D
13. de la Luz Garcia-Hernandez M
14. Ulland TK
15. Darby M
16. Park E
17. Karim F
18. Melocchi L
19. Madansein R
20. Dullabh KJ
21. Dunlap M
22. Marin-Agudelo N
23. Ebihara T
24. Ndung'u T
25. Kaushal D
26. Pym AS
27. Kolls JK
28. Steyn A
29. Zúñiga J
30. Horsnell W
31. Yokoyama WM
32. Shalek AK
33. Kløverpris HN
34. Colonna M
35. Leslie A
36. Khader SA
Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.; Nature. 2019 Jul 24.
1. Ardain A
2. Domingo-Gonzalez R
3. Das S
4. Kazer SW
5. Howard NC
6. Singh A
7. Ahmed M
8. Nhamoyebonde S
9. Rangel-Moreno J
10. Ogongo P
11. Lu L
12. Ramsuran D
13. de la Luz Garcia-Hernandez M
14. K Ulland T
15. Darby M
16. Park E
17. Karim F
18. Melocchi L
19. Madansein R
20. Dullabh KJ
21. Dunlap M
22. Marin-Agudelo N
23. Ebihara T
24. Ndung'u T
25. Kaushal D
26. Pym AS
27. Kolls JK
28. Steyn A
29. Zúñiga J
30. Horsnell W
31. Yokoyama WM
32. Shalek AK
33. Kløverpris HN
34. Colonna M
35. Leslie A
36. Khader SA
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.; Nature. 2019 Jun 05.
1. Bell DR
2. Wu E
3. Rudmann C
4. Forney M
5. Kaiser C
6. Wood R
7. Chakkalakal J
8. Paris N
9. Klose A
10. Xiao GQ
11. Rangel-Moreno J
12. Garcia-Hernandez M
13. Ritchlin C
14. Schwarz E
15. Rahimi H
Selective sexual dimorphism in musculoskeletal-cardiopulmonary pathologies and mortality in the TNF-transgenic mouse model of rheumatoid arthritis.; Arthritis & rheumatology (Hoboken, N.J.). 2019 Apr 10.
1. Lerman I
2. Ma X
3. Seger C
4. Maolake A
5. Garcia-Hernandez ML
6. Rangel-Moreno J
7. Ackerman J
8. Nastiuk KL
9. Susiarjo M
10. Hammes SR
Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression.; Molecular cancer research : MCR. 2019 Jan 04.
1. Paine A
2. Woeller CF
3. Zhang H
4. de la Luz Garcia-Hernandez M
5. Huertas N
6. Xing L
7. Phipps RP
8. Ritchlin CT
Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 32(6). 2018 Jun.
1. Domingo-Gonzalez R
2. Das S
3. Griffiths KL
4. Ahmed M
5. Bambouskova M
6. Gopal R
7. Gondi S
8. Muñoz-Torrico M
9. Salazar-Lezama MA
10. Cruz-Lagunas A
11. Jiménez-Álvarez L
12. Ramirez-Martinez G
13. Espinosa-Soto R
14. Sultana T
15. Lyons-Weiler J
16. Reinhart TA
17. Arcos J
18. de la Luz Garcia-Hernandez M
19. Mastrangelo MA
20. Al-Hammadi N
21. Townsend R
22. Balada-Llasat JM
23. Torrelles JB
24. Kaplan G
25. Horne W
26. Kolls JK
27. Artyomov MN
28. Rangel-Moreno J
29. Zúñiga J
30. Khader SA
Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis.; JCI insight; Vol 2(19). 2017 Oct 05.
1. Lerman I
2. Garcia-Hernandez ML
3. Rangel-Moreno J
4. Chiriboga L
5. Pan C
6. Nastiuk KL
7. Krolewski JJ
8. Sen A
9. Hammes SR
Infiltrating Myeloid Cells Exert Pro-Tumorigenic Actions via Neutrophil Elastase.; Molecular cancer research : MCR. 2017 May 16.
1. Eddens T
2. Elsegeiny W
3. Garcia-Hernadez ML
4. Castillo P
5. Trevejo-Nunez G
6. Serody K
7. Campfield BT
8. Khader SA
9. Chen K
10. Rangel-Moreno J
11. Kolls JK
Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.; Cell reports; Vol 18(13). 2017 Mar 28.
1. García-Hernández ML
2. Uribe-Uribe NO
3. Espinosa-González R
4. Kast WM
5. Khader SA
6. Rangel-Moreno J
A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression.; Frontiers in immunology; Vol 8. 2017.
1. Rangel-Moreno J
2. de la Luz Garcia-Hernandez M
3. Ramos-Payan R
4. Biear J
5. Hernady E
6. Sangster MY
7. Randall TD
8. Johnston CJ
9. Finkelstein JN
10. Williams JP
Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function.; Radiation research; Vol 184(4). 2015 Oct.
1. Barone F
2. Nayar S
3. Campos J
4. Cloake T
5. Withers DR
6. Toellner KM
7. Zhang Y
8. Fouser L
9. Fisher B
10. Bowman S
11. Rangel-Moreno J
12. Garcia-Hernandez Mde L
13. Randall TD
14. Lucchesi D
15. Bombardieri M
16. Pitzalis C
17. Luther SA
18. Buckley CD
IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs.; Proceedings of the National Academy of Sciences of the United States of America; Vol 112(35). 2015 Sep 01.
1. Zhu Q
2. Yamakuchi M
3. Ture S
4. de la Luz Garcia-Hernandez M
5. Ko KA
6. Modjeski KL
7. LoMonaco MB
8. Johnson AD
9. O'Donnell CJ
10. Takai Y
11. Morrell CN
12. Lowenstein CJ
Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.; The Journal of clinical investigation; Vol 124(10). 2014 Oct.
1. Hamada H
2. Bassity E
3. Flies A
4. Strutt TM
5. Garcia-Hernandez Mde L
6. McKinstry KK
7. Zou T
8. Swain SL
9. Dutton RW
Multiple redundant effector mechanisms of CD8+ T cells protect against influenza infection.; Journal of immunology (Baltimore, Md. : 1950); Vol 190(1). 2013 Jan 01.
1. Brown DM
2. Lee S
3. Garcia-Hernandez Mde L
4. Swain SL
Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection.; Journal of virology; Vol 86(12). 2012 Jun.
1. Rangel-Moreno J
2. Carragher DM
3. de la Luz Garcia-Hernandez M
4. Hwang JY
5. Kusser K
6. Hartson L
7. Kolls JK
8. Khader SA
9. Randall TD
The development of inducible bronchus-associated lymphoid tissue depends on IL-17.; Nature immunology; Vol 12(7). 2011 Jul.
1. Garcia-Hernandez Mde L
2. Hamada H
3. Reome JB
4. Misra SK
5. Tighe MP
6. Dutton RW
Adoptive transfer of tumor-specific Tc17 effector T cells controls the growth of B16 melanoma in mice.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(8). 2010 Apr 15.
1. Gray A
2. de la Luz Garcia-Hernandez M
3. van West M
4. Kanodia S
5. Hubby B
6. Kast WM
Prostate cancer immunotherapy yields superior long-term survival in TRAMP mice when administered at an early stage of carcinogenesis prior to the establishment of tumor-associated immunosuppression at later stages.; Vaccine; Vol 27 Suppl 6. 2009 Dec 30.
1. Hamada H
2. Garcia-Hernandez Mde L
3. Reome JB
4. Misra SK
5. Strutt TM
6. McKinstry KK
7. Cooper AM
8. Swain SL
9. Dutton RW
Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge.; Journal of immunology (Baltimore, Md. : 1950); Vol 182(6). 2009 Mar 15.
1. López-Camarillo C
2. de la Luz García-Hernández M
3. Marchat LA
4. Luna-Arias JP
5. Hernández de la Cruz O
6. Mendoza L
7. Orozco E
Entamoeba histolytica EhDEAD1 is a conserved DEAD-box RNA helicase with ATPase and ATP-dependent RNA unwinding activities.; Gene; Vol 414(1-2). 2008 May 15.
1. Garcia-Hernandez Mde L
2. Gray A
3. Hubby B
4. Klinger OJ
5. Kast WM
Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity.; Cancer research; Vol 68(3). 2008 Feb 01.
1. Garcia-Hernandez Mde L
2. Gray A
3. Hubby B
4. Kast WM
In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer.; Cancer research; Vol 67(3). 2007 Feb 01.
1. Hernandez-Pando R
2. Aguilar D
3. Hernandez ML
4. Orozco H
5. Rook G
Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis.; European journal of immunology; Vol 34(1). 2004 Jan.
1. Koh YT
2. Garcia-Hernandez MA
3. Kast WM
Tumor Escape Immune Mechanisms; Cancer Drug Discovery and Development: Cancer Drug Resistance. 2004 Jan 01.
1. Bornstein-Quevedo L
2. García-Hernández ML
3. Camacho-Arroyo I
4. Herrera MF
5. Angeles AA
6. Treviño OG
7. Gamboa-Domínguez A
Telomerase activity in well-differentiated papillary thyroid carcinoma correlates with advanced clinical stage of the disease.; Endocrine pathology; Vol 14(3). 2003.
1. Rangel Moreno J
2. Estrada García I
3. De La Luz García Hernández M
4. Aguilar Leon D
5. Marquez R
6. Hernández Pando R
The role of prostaglandin E2 in the immunopathogenesis of experimental pulmonary tuberculosis.; Immunology; Vol 106(2). 2002 Jun.
1. García-Hernández ML
2. Hernández-Pando R
3. Gariglio P
4. Berumen J
Interleukin-10 promotes B16-melanoma growth by inhibition of macrophage functions and induction of tumour and vascular cell proliferation.; Immunology; Vol 105(2). 2002 Feb.