URMC / Labs / Garcia-Hernandez Lab / Publications Publications Nogales AChiem KLorenzo MMRangel-Moreno Jde la Luz Garcia-Hernandez MPark JGBlasco RMartinez-Sobrido L Evaluation of Vaccinia Virus Infection in Mice Using Two-Reporter Recombinant Virus.; Methods in molecular biology (Clifton, N.J.); Vol 2860, pp. 157-174. 2025. Van Buren EAzzara DRangel-Moreno JGarcia-Hernandez MLMurphy SPCohen EDLewis ELin XPark HR Single-cell RNA sequencing reveals placental response under environmental stress.; Nature communications; Vol 15(1), pp. 6549. 2024 Aug 02. Ritchlin CTRangel-Moreno JMartino DIsett BPaine ABhattacharya SFox JMeyer EMBao RBruno TTausk Fde la Luz Garcia-Hernandez M Psoriatic arthritis subtypes are phenocopied in humanized mice.; JCI insight; Vol 9(15). 2024 Jul 02. Furuya HNguyen CTChan TMarusina AIMerleev AAGarcia-Hernandez MLHsieh SLTsokos GCRitchlin CTTagkopoulos IMaverakis EAdamopoulos IE IL-23 induces CLEC5A+ IL-17A+ neutrophils and elicit skin inflammation associated with psoriatic arthritis.; Journal of autoimmunity; Vol 143, pp. 103167. 2024 Jan 31. Constantinesco NJChinnappan BDeVito LJMoras CSrikanth SGarcia-Hernandez MLRangel-Moreno JGopal R Sodium-Glucose Cotransporter-2 Inhibitor, Empagliflozin, Suppresses the Inflammatory Immune Response to Influenza Infection.; ImmunoHorizons; Vol 7(12), pp. 861-871. 2023 Dec 01. Castillo RLSidhu IDolgalev IChu TPrystupa ASubudhi IYan DKonieczny PHsieh BHaberman RHSelvaraj SShiomi TMedina RGirija PVHeguy ALoomis CAChiriboga LRitchlin CGarcia-Hernandez MLCarucci JMeehan SANeimann ALGudjonsson JEScher JUNaik S Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems.; Science immunology; Vol 8(84), pp. eabq7991. 2023 Jun 02. Quijada PPark SZhao PKolluri KSWong DShih KDFang KPezhouman AWang LDaraei ATran MDRathbun EMBurgos Villar KNGarcia-Hernandez MLPham TTLowenstein CJIruela-Arispe MLCarmichael STSmall EMArdehali R Cardiac pericytes mediate the remodeling response to myocardial infarction.; The Journal of clinical investigation; Vol 133(10). 2023 May 15. Swanson RVGupta AForeman TWLu LChoreno-Parra JAMbandi SKRosa BAAkter SDas SAhmed MGarcia-Hernandez MLSingh DKEsaulova EArtyomov MNGommerman JMehra SZuniga JMitreva MScriba TJRangel-Moreno JKaushal DKhader SA Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.; Nature immunology. 2023 Apr 03. Paine ABrookes PSBhattacharya SLi DGarcia-Hernandez MLTausk FRitchlin C Dysregulation of bile acids, lipids, and nucleotides in psoriatic arthritis revealed by unbiased profiling of serum metabolites.; Arthritis & rheumatology (Hoboken, N.J.). 2022 Jul 11. Garcia-Hernandez MARitchlin CT New Tech Provides Insights into the Pathogenesis of Psoriatic Arthritis; The Rheumatologist. 2022 Jan 01. Rangel-Moreno JGarcia-Hernandez MLOwen TBarnard JBecerril-Villanueva EKashyap TArgueta CGamboa-Dominguez ATamir SLandesman YGoldman BIRitchlin CTAnolik JH Small molecule inhibitors of nuclear export ameliorate lupus by modulating plasma cell generation and survival.; Arthritis & rheumatology (Hoboken, N.J.). 2022 Mar 25. Garcia-Hernandez MLRangel-Moreno JGarcia-Castaneda MKenney HMPaine AThullen MAnandarajah APSchwarz EMDirksen RTRitchlin CT Dendritic cell-specific transmembrane protein is required for synovitis and bone resorption in inflammatory arthritis.; Frontiers in immunology; Vol 13, pp. 1026574. 2022 Jan 07. Chiem KLorenzo MMRangel-Moreno JGarcia-Hernandez MLPark JGNogales ABlasco RMartínez-Sobrido L Bi-Reporter Vaccinia Virus for Tracking Viral Infections In Vitro and In Vivo.; Microbiology spectrum. 2021 Nov 24. Esaulova EDas SSingh DKChoreño-Parra JASwain AArthur LRangel-Moreno JAhmed MSingh BGupta AFernández-López LAde la Luz Garcia-Hernandez MBucsan AMoodley CMehra SGarcía-Latorre EZuniga JAtkinson JKaushal DArtyomov MNKhader SA The immune landscape in tuberculosis reveals populations linked to disease and latency.; Cell host & microbe. 2020 Dec 16. Bell RDWhite RJGarcia-Hernandez MLWu ERahimi HMarangoni RGSlattery PDuemmel SNuzzo MHuertas NYee MO'Reilly MAMorrell CRitchlin CTSchwarz EMKorman BD TNF Induces Obliterative Pulmonary Vascular Disease in a Novel Model of Connective Tissue Disease Associated Pulmonary Arterial Hypertension (CTD-PAH).; Arthritis & rheumatology (Hoboken, N.J.). 2020 May 10. Taya MGarcia-Hernandez MRangel-Moreno JMinor BGibbons EHammes SR Neutrophil elastase from myeloid cells promotes TSC2-null tumor growth.; Endocrine-related cancer. 2020 Feb 01. Hwang JYSilva-Sanchez ACarragher DMGarcia-Hernandez MLRangel-Moreno JRandall TD Inducible Bronchus-Associated Lymphoid Tissue (iBALT) Attenuates Pulmonary Pathology in a Mouse Model of Allergic Airway Disease.; Frontiers in immunology; Vol 11. 2020. Ardain ADomingo-Gonzalez RDas SKazer SWHoward NCSingh AAhmed MNhamoyebonde SRangel-Moreno JOgongo PLu LRamsuran Dde la Luz Garcia-Hernandez MUlland TKDarby MPark EKarim FMelocchi LMadansein RDullabh KJDunlap MMarin-Agudelo NEbihara TNdung'u TKaushal DPym ASKolls JKSteyn AZúñiga JHorsnell WYokoyama WMShalek AKKløverpris HNColonna MLeslie AKhader SA Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.; Nature. 2019 Jul 24. Ardain ADomingo-Gonzalez RDas SKazer SWHoward NCSingh AAhmed MNhamoyebonde SRangel-Moreno JOgongo PLu LRamsuran Dde la Luz Garcia-Hernandez MK Ulland TDarby MPark EKarim FMelocchi LMadansein RDullabh KJDunlap MMarin-Agudelo NEbihara TNdung'u TKaushal DPym ASKolls JKSteyn AZúñiga JHorsnell WYokoyama WMShalek AKKløverpris HNColonna MLeslie AKhader SA Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.; Nature. 2019 Jun 05. Bell DRWu ERudmann CForney MKaiser CWood RChakkalakal JParis NKlose AXiao GQRangel-Moreno JGarcia-Hernandez MRitchlin CSchwarz ERahimi H Selective sexual dimorphism in musculoskeletal-cardiopulmonary pathologies and mortality in the TNF-transgenic mouse model of rheumatoid arthritis.; Arthritis & rheumatology (Hoboken, N.J.). 2019 Apr 10. Lerman IMa XSeger CMaolake AGarcia-Hernandez MLRangel-Moreno JAckerman JNastiuk KLSusiarjo MHammes SR Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression.; Molecular cancer research : MCR. 2019 Jan 04. Paine AWoeller CFZhang Hde la Luz Garcia-Hernandez MHuertas NXing LPhipps RPRitchlin CT Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 32(6). 2018 Jun. Domingo-Gonzalez RDas SGriffiths KLAhmed MBambouskova MGopal RGondi SMuñoz-Torrico MSalazar-Lezama MACruz-Lagunas AJiménez-Álvarez LRamirez-Martinez GEspinosa-Soto RSultana TLyons-Weiler JReinhart TAArcos Jde la Luz Garcia-Hernandez MMastrangelo MAAl-Hammadi NTownsend RBalada-Llasat JMTorrelles JBKaplan GHorne WKolls JKArtyomov MNRangel-Moreno JZúñiga JKhader SA Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis.; JCI insight; Vol 2(19). 2017 Oct 05. Lerman IGarcia-Hernandez MLRangel-Moreno JChiriboga LPan CNastiuk KLKrolewski JJSen AHammes SR Infiltrating Myeloid Cells Exert Pro-Tumorigenic Actions via Neutrophil Elastase.; Molecular cancer research : MCR. 2017 May 16. Eddens TElsegeiny WGarcia-Hernadez MLCastillo PTrevejo-Nunez GSerody KCampfield BTKhader SAChen KRangel-Moreno JKolls JK Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.; Cell reports; Vol 18(13). 2017 Mar 28. García-Hernández MLUribe-Uribe NOEspinosa-González RKast WMKhader SARangel-Moreno J A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression.; Frontiers in immunology; Vol 8. 2017. Rangel-Moreno Jde la Luz Garcia-Hernandez MRamos-Payan RBiear JHernady ESangster MYRandall TDJohnston CJFinkelstein JNWilliams JP Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function.; Radiation research; Vol 184(4). 2015 Oct. Barone FNayar SCampos JCloake TWithers DRToellner KMZhang YFouser LFisher BBowman SRangel-Moreno JGarcia-Hernandez Mde LRandall TDLucchesi DBombardieri MPitzalis CLuther SABuckley CD IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs.; Proceedings of the National Academy of Sciences of the United States of America; Vol 112(35). 2015 Sep 01. Zhu QYamakuchi MTure Sde la Luz Garcia-Hernandez MKo KAModjeski KLLoMonaco MBJohnson ADO'Donnell CJTakai YMorrell CNLowenstein CJ Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.; The Journal of clinical investigation; Vol 124(10). 2014 Oct. Hamada HBassity EFlies AStrutt TMGarcia-Hernandez Mde LMcKinstry KKZou TSwain SLDutton RW Multiple redundant effector mechanisms of CD8+ T cells protect against influenza infection.; Journal of immunology (Baltimore, Md. : 1950); Vol 190(1). 2013 Jan 01. Brown DMLee SGarcia-Hernandez Mde LSwain SL Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection.; Journal of virology; Vol 86(12). 2012 Jun. Rangel-Moreno JCarragher DMde la Luz Garcia-Hernandez MHwang JYKusser KHartson LKolls JKKhader SARandall TD The development of inducible bronchus-associated lymphoid tissue depends on IL-17.; Nature immunology; Vol 12(7). 2011 Jul. Garcia-Hernandez Mde LHamada HReome JBMisra SKTighe MPDutton RW Adoptive transfer of tumor-specific Tc17 effector T cells controls the growth of B16 melanoma in mice.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(8). 2010 Apr 15. Gray Ade la Luz Garcia-Hernandez Mvan West MKanodia SHubby BKast WM Prostate cancer immunotherapy yields superior long-term survival in TRAMP mice when administered at an early stage of carcinogenesis prior to the establishment of tumor-associated immunosuppression at later stages.; Vaccine; Vol 27 Suppl 6. 2009 Dec 30. Hamada HGarcia-Hernandez Mde LReome JBMisra SKStrutt TMMcKinstry KKCooper AMSwain SLDutton RW Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge.; Journal of immunology (Baltimore, Md. : 1950); Vol 182(6). 2009 Mar 15. López-Camarillo Cde la Luz García-Hernández MMarchat LALuna-Arias JPHernández de la Cruz OMendoza LOrozco E Entamoeba histolytica EhDEAD1 is a conserved DEAD-box RNA helicase with ATPase and ATP-dependent RNA unwinding activities.; Gene; Vol 414(1-2). 2008 May 15. Garcia-Hernandez Mde LGray AHubby BKlinger OJKast WM Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity.; Cancer research; Vol 68(3). 2008 Feb 01. Garcia-Hernandez Mde LGray AHubby BKast WM In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer.; Cancer research; Vol 67(3). 2007 Feb 01. Hernandez-Pando RAguilar DHernandez MLOrozco HRook G Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis.; European journal of immunology; Vol 34(1). 2004 Jan. Koh YTGarcia-Hernandez MAKast WM Tumor Escape Immune Mechanisms; Cancer Drug Discovery and Development: Cancer Drug Resistance. 2004 Jan 01. Bornstein-Quevedo LGarcía-Hernández MLCamacho-Arroyo IHerrera MFAngeles AATreviño OGGamboa-Domínguez A Telomerase activity in well-differentiated papillary thyroid carcinoma correlates with advanced clinical stage of the disease.; Endocrine pathology; Vol 14(3). 2003. Rangel Moreno JEstrada García IDe La Luz García Hernández MAguilar Leon DMarquez RHernández Pando R The role of prostaglandin E2 in the immunopathogenesis of experimental pulmonary tuberculosis.; Immunology; Vol 106(2). 2002 Jun. García-Hernández MLHernández-Pando RGariglio PBerumen J Interleukin-10 promotes B16-melanoma growth by inhibition of macrophage functions and induction of tumour and vascular cell proliferation.; Immunology; Vol 105(2). 2002 Feb.