Lab Members
Lab Members
Principal Investigator
Research Interest: Identify the expression patterns of the major categories of stem and progenitor cells of the adult human brain and to use that information to define the signaling pathways that distinguish one progenitor from another, as well as those that distinguish brain tumor stem and progenitor cells from their normal counterparts.
Faculty
Research Interest:
Development of new analytical methods to better understand in-vivo dynamics of glial replacement
Research Interest: The use of gene therapeutic strategies to induce and regulate neurogenesis from endogenous neural stem cells in the adult mammalian brain, with a particular emphasis on developing this as a therapeutic strategy in Huntington's disease.
Research Interest: Generation of iPSC and hESC-derived glial progenitor cells for cell therapy.
Research Interest: Transcriptomic and epigenetic regulation of schizophrenia and other psychotic disorders. Application of machine learning techniques to characterize and assess the quality of engineered glial cells.
Research Interest: Multi-omic bulk and single cell sequencing analyses of human glial chimeric mice to unravel the transcriptional underpinnings of human glial dysfunction in disease.
Research Interest:
Generation of human-glial chimeric mice to model and evaluate cell therapeutic interventions of CNS disease.
Research Interest: Focusing on preclinical and clinical translation of Glia
Progenitor Cells
Research Interest:
Surgical and histological techniques to support in vivo analysis of human glial progenitor cells in chimerized brain models for the goal of translating therapies in glial based neurodegenerative disorders.
