Lab Members

Research Interest: Identify the expression patterns of the major categories of stem and progenitor cells of the adult human brain and to use that information to define the signaling pathways that distinguish one progenitor from another, as well as those that distinguish brain tumor stem and progenitor cells from their normal counterparts.

Research Interest: The use of gene therapeutic strategies to induce and regulate neurogenesis from endogenous neural stem cells in the adult mammalian brain, with a particular emphasis on developing this as a therapeutic strategy in Huntington's disease.

Research Interest: Generation of iPSC and hESC-derived glial progenitor cells for cell therapy.

Research Interest: Transcriptomic and epigenetic regulation of schizophrenia and other psychotic disorders. Application of machine learning techniques to characterize and assess the quality of engineered glial cells.

Research Interest: Multi-omic bulk and single cell sequencing analyses of human glial chimeric mice to unravel the transcriptional underpinnings of human glial dysfunction in disease.

Research Interest: Focusing on preclinical and clinical translation of Glia Progenitor Cells

Research Interest: The use of glial progenitor cells for treating disorders of myelin, in both pediatric and adult animal models of myelin disease. She also studies the biology of human astrocytes and oligodendrocytes in vivo, in chimeric brain models that permit the assessment of human cells in vivo, in rodent models of neurological diseases, including those of mental illness, such as schizophrenia.