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URMC / Labs / Harris Lab / Projects / Genetically-Engineered Mouse Models
 

Genetically-Engineered Mouse Models

For decades, genetically engineered mouse models (GEMMs) have been used to better understand cellular processes and their effects within a living animal. GEMMs can be used to study normal physiology, such as mammary gland developed (right), as well as pathophysiology, such as the MMTV-PyMT mouse model that spontaneously develops breast cancer. In the Harris lab, we use a variety of GEMMs to understand the roles of antioxidants in disease, with a focus on cancer development and progression.

Mammary Gland Image

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