Publications

• 1. Kates SL
  2. Owen JR
  3. Beck CA
  4. Muthukrishnan G
  5. Daiss JL
  6. Golladay GJ
  Dilution of humoral immunity: Results from a natural history study of healthy total knee arthroplasty patients.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024 Jul 25.
• 1. Botros M
  2. de Mesy Bentley KL
  3. Schloemann DT
  4. Saito M
  5. Constantine R
  6. Ricciardi BF
  7. Muthukrishnan G
  Cutibacterium acnes invades submicron osteocyte lacuno-canalicular networks following implant-associated osteomyelitis.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024 Jul 24.
• 1. Hofstee MI
  2. Siverino C
  3. Saito M
  4. Meghwani H
  5. Tapia-Dean J
  6. Arveladze S
  7. Hildebrand M
  8. Rangel-Moreno J
  9. Riool M
  10. Zeiter S
  11. Zaat SAJ
  12. Moriarty TF
  13. Muthukrishnan G
  Staphylococcus aureus Panton-Valentine Leukocidin worsens acute implant-associated osteomyelitis in humanized BRGSF mice.; JBMR plus; Vol 8(2), pp. ziad005. 2024 Jan 04.
• 1. Kenney HM
  2. Rangel-Moreno J
  3. Peng Y
  4. Chen KL
  5. Bruno J
  6. Embong A
  7. Pritchett E
  8. Fox JI
  9. Becerril-Villanueva E
  10. Gamboa-Domínguez A
  11. Quataert S
  12. Muthukrishnan G
  13. Wood RW
  14. Korman BD
  15. Anolik JH
  16. Xing L
  17. Ritchlin CT
  18. Schwarz EM
  19. Wu CL
  Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.; Frontiers in immunology; Vol 14, pp. 1237498. 2023 Aug 25.
• 1. Hachem AA
  2. Filkins LM
  3. Kidane YH
  4. Raj P
  5. Tareen NG
  6. Arana CA
  7. Muthukrishnan G
  8. Copley LA
  Staphylococcus aureus isolates from children with clinically differentiated osteomyelitis exhibit distinct transcriptomic signatures.; PloS one; Vol 18(8), pp. e0288758. 2023 Aug 10.
• 1. Schwarz EM
  2. Archer NK
  3. Atkins GJ
  4. Bentley KLM
  5. Botros M
  6. Cassat JE
  7. Chisari E
  8. Coraça-Huber DC
  9. Daiss JL
  10. Gill SR
  11. Goodman SB
  12. Harro J
  13. Hernandez CJ
  14. Ivashkiv LB
  15. Kates SL
  16. Marques CNH
  17. Masters EA
  18. Muthukrishnan G
  19. Owen JR
  20. Raafat D
  21. Saito M
  22. Veis DJ
  23. Xie C
  The 2023 Orthopaedic Research Society's International Consensus Meeting on musculoskeletal infection: Summary from the host immunity section.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023 Jan 16.
• 1. Bui TI
  2. Britt EA
  3. Muthukrishnan G
  4. Gill SR
  Probiotic induced synthesis of microbiota polyamine as a nutraceutical for metabolic syndrome and obesity-related type 2 diabetes.; Frontiers in endocrinology; Vol 13, pp. 1094258. 2023 Jan 13.
• 1. Xie C
  2. Ren Y
  3. Weeks J
  4. Rainbolt J
  5. Mark Kenney H
  6. Xue T
  7. Allen F
  8. Shu Y
  9. Tay AJH
  10. Lekkala S
  11. Yeh SA
  12. Muthukrishnan G
  13. Gill AL
  14. Gill SR
  15. Kim M
  16. Kates SL
  17. Schwarz EM
  Longitudinal Intravital Imaging of the Bone Marrow (LIMB) for Analysis of the Race for the Surface in a Murine Osteomyelitis Model.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023 Jan 09.
• 1. Morita Y
  2. Saito M
  3. Rangel-Moreno J
  4. Franchini AM
  5. Owen JR
  6. Martinez JC
  7. Daiss JL
  8. de Mesy Bentley KL
  9. Kates SL
  10. Schwarz EM
  11. Muthukrishnan G
  Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation.; Bone research; Vol 10(1), pp. 56. 2022 Aug 26.
• 1. Sherchand SP
  2. Adhikari RP
  3. Muthukrishnan G
  4. Kanipakala T
  5. Owen JR
  6. Xie C
  7. Aman MJ
  8. Proctor RA
  9. Schwarz EM
  10. Kates SL
  Evidence of Neutralizing and Non-Neutralizing Anti-Glucosaminidase Antibodies in Patients With S. Aureus Osteomyelitis and Their Association With Clinical Outcome Following Surgery in a Clinical Pilot.; Frontiers in cellular and infection microbiology; Vol 12, pp. 876898. 2022 Jul 18.
• 1. Masters EA
  2. Ricciardi BF
  3. Bentley KLM
  4. Moriarty TF
  5. Schwarz EM
  6. Muthukrishnan G
  Skeletal infections: microbial pathogenesis, immunity and clinical management.; Nature reviews. Microbiology. 2022 Feb 15.
• 1. Campbell MP
  2. Mott MD
  3. Owen JR
  4. Reznicek JE
  5. Beck CA
  6. Muthukrishnan G
  7. Golladay GJ
  8. Kates SL
  Low albumin level is more strongly associated with adverse outcomes and Staphylococcus aureus infection than hemoglobin A1C or smoking tobacco.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2022 Feb 04.
• 1. Klose AM
  2. Daiss JL
  3. Ho L
  4. Beck CA
  5. Striemer CC
  6. Muthukrishnan G
  7. Miller BL
  StaphAIR: A Label-Free Antigen Microarray Approach to Detecting Anti-Staphylococcus aureus Antibody Responses in Orthopedic Infections.; Analytical chemistry. 2021 Oct 01.
• 1. Owen JR
  2. Campbell MP
  3. Mott MD
  4. Beck CA
  5. Xie C
  6. Muthukrishnan G
  7. Daiss JL
  8. Schwarz EM
  9. Kates SL
  IgG4-specific responses in patients with Staphylococcus aureus bone infections are not predictive of postoperative complications.; European cells & materials; Vol 41. 2021 Sep 22.
• 1. Burch MA
  2. Keshishian A
  3. Wittmann C
  4. Nehrbass D
  5. Styger U
  6. Muthukrishnan G
  7. Arens D
  8. Stadelmann VA
  9. Richards RG
  10. Moriarty TF
  11. Thompson K
  The non-steroidal anti-inflammatory drug carprofen negatively impacts new bone formation and antibiotic efficacy in a rat model of orthopaedic-device-related infection.; European cells & materials; Vol 41, pp. 739-755. 2021 Jun 17.
• 1. Adjei-Sowah E
  2. Peng Y
  3. Weeks J
  4. Jonason JH
  5. de Mesy Bentley KL
  6. Masters E
  7. Morita Y
  8. Muthukrishnan G
  9. Cherian P
  10. Hu XE
  11. McKenna CE
  12. Ebetino FH
  13. Sun S
  14. Schwarz EM
  15. Xie C
  Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid.; Antibiotics (Basel, Switzerland); Vol 10(6). 2021 Jun 17.
• 1. Cole CL
  2. Bachman JF
  3. Ye J
  4. Murphy J
  5. Gerber SA
  6. Beck CA
  7. Boyce BF
  8. Muthukrishnan G
  9. Chakkalakal JV
  10. Schwarz EM
  11. Linehan D
  Increased myocellular lipid and IGFBP-3 expression in a pre-clinical model of pancreatic cancer-related skeletal muscle wasting.; Journal of cachexia, sarcopenia and muscle. 2021 May 07.
• 1. de Mesy Bentley KL
  2. Galloway CA
  3. Muthukrishnan G
  4. Echternacht SR
  5. Masters EA
  6. Zeiter S
  7. Schwarz EM
  8. Leckenby JI
  Emerging electron microscopy and 3D methodologies to interrogate Staphylococcus aureus osteomyelitis in murine models.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 39(2). 2021 Feb.
• 1. Moriarty TF
  2. Muthukrishnan G
  3. Daiss JL
  4. Xie C
  5. Nishitani K
  6. Morita Y
  7. Awad H
  8. de Mesy Bentley KL
  9. Masters E
  10. Bui T
  11. Yan M
  12. Owen J
  13. Mooney B
  14. Gill S
  15. Puetzler J
  16. Wenke JC
  17. Morgenstern M
  18. Metsemakers WJ
  19. Noll C
  20. Joeris A
  21. Richards RG
  22. Schwarz EM
  23. Kates SL
  Bone infection: a clinical priority for clinicians, scientists and educators.; European cells & materials; Vol 41. 2021 Jan 18.
• 1. Masters EA
  2. Muthukrishnan G
  3. Ho L
  4. Gill AL
  5. de Mesy Bentley KL
  6. Galloway CA
  7. McGrath JL
  8. Awad HA
  9. Gill SR
  10. Schwarz EM
  Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis.; Frontiers in microbiology; Vol 12. 2021.
• 1. Muthukrishnan G
  2. Wallimann A
  3. Rangel-Moreno J
  4. Bentley KLM
  5. Hildebrand M
  6. Mys K
  7. Kenney HM
  8. Sumrall ET
  9. Daiss JL
  10. Zeiter S
  11. Richards RG
  12. Schwarz EM
  13. Moriarty TF
  Humanized Mice Exhibit Exacerbated Abscess Formation and Osteolysis During the Establishment of Implant-Associated Staphylococcus aureus Osteomyelitis.; Frontiers in immunology; Vol 12. 2021.
• 1. Morita Y
  2. Masters EA
  3. Schwarz EM
  4. Muthukrishnan G
  Interleukin-27 and Its Diverse Effects on Bacterial Infections.; Frontiers in immunology; Vol 12. 2021.
• 1. Fu W
  2. He W
  3. Ren Y
  4. Li Z
  5. Liu J
  6. Liu Y
  7. Xie Z
  8. Xu J
  9. Bi Q
  10. Kong M
  11. Lee CC
  12. Daiss JL
  13. Muthukrishnan G
  14. Owen JR
  15. Kates SL
  16. Peng J
  17. Xie C
  Distinct Expression Trend of Signature Antigens of Staphylococcus Aureus Osteomyelitis Correlated with Clinical Outcomes.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2020 Dec 18.
• 1. Muthukrishnan G
  2. Beck CA
  3. Owen JR
  4. Xie C
  5. Kates SL
  6. Daiss JL
  Serum antibodies against Staphylococcus aureus can prognose treatment success in patients with bone infections.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2020 Dec 15.
• 1. Kates SL
  2. Owen JR
  3. Beck CA
  4. Xie C
  5. Muthukrishnan G
  6. Daiss JL
  7. Schwarz EM
  Lack of Humoral Immunity Against Glucosaminidase Is Associated with Postoperative Complications in Staphylococcus aureus Osteomyelitis.; The Journal of bone and joint surgery. American volume. 2020 Aug 27.
• 1. Muthukrishnan G
  2. Soin S
  3. Beck CA
  4. Grier A
  5. Brodell JD
  6. Lee CC
  7. Ackert-Bicknell CL
  8. Lee FE
  9. Schwarz EM
  10. Daiss JL
  A Bioinformatic Approach to Utilize a Patient's Antibody-Secreting Cells against Staphylococcus aureus to Detect Challenging Musculoskeletal Infections.; ImmunoHorizons; Vol 4(6). 2020 Jun 22.
• 1. Hofstee MI
  2. Muthukrishnan G
  3. Atkins GJ
  4. Riool M
  5. Thompson K
  6. Morgenstern M
  7. Stoddart MJ
  8. Richards RG
  9. Zaat SAJ
  10. Moriarty TF
  Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods.; The American journal of pathology; Vol 190(6), pp. 1151-1163. 2020 Mar 16.
• 1. Tourtelot E
  2. Quataert S
  3. Glantz JC
  4. Perlis L
  5. Muthukrishnan G
  6. Mosmann T
  Women who received varicella vaccine versus natural infection have different long-term T cell immunity but similar antibody levels.; Vaccine; Vol 38(7). 2020 Feb 11.
• 1. Lee CC
  2. Southgate RD
  3. Jiao C
  4. Gersz E
  5. Owen JR
  6. Kates SL
  7. Beck CA
  8. Xie C
  9. Daiss JL
  10. Post V
  11. Moriarty TF
  12. Zeiter S
  13. Schwarz EM
  14. Muthukrishnan G
  Deriving a dose and regimen for anti-glucosaminidase antibody passive-immunisation for patients with Staphylococcus aureus osteomyelitis.; European cells & materials; Vol 39. 2020 Jan 31.
• 1. Ricciardi BF
  2. Muthukrishnan G
  3. Masters EA
  4. Kaplan N
  5. Daiss JL
  6. Schwarz EM
  New Developments and Future Challenges in Prevention, Diagnosis, and Treatment of Prosthetic Joint Infection.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2020 Jan 22.
• 1. Muthukrishnan G
  2. Masters EA
  3. Daiss JL
  4. Schwarz EM
  Mechanisms of Immune Evasion and Bone Tissue Colonization That Make Staphylococcus aureus the Primary Pathogen in Osteomyelitis.; Current osteoporosis reports; Vol 17(6). 2019 Dec.
• 1. Masters EA
  2. Trombetta R
  3. Bentley KL
  4. Boyce BF
  5. Gill AL
  6. Gill SR
  7. Nishitani K
  8. Ishikawa M
  9. Morita Y
  10. Ito H
  11. Bello-Irizarry SN
  12. Ninomiya M
  13. Brodell J
  14. Lee CC
  15. Hao S
  16. Oh I
  17. Xie C
  18. Awad HA
  19. Daiss JL
  20. Owen JR
  21. Kates SL
  22. Schwarz EM
  23. Muthukrishnan G
  Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy"; Nature Bone Research; Vol 7(20). 2019 Jan 01.
• 1. Masters EA
  2. Trombetta RP
  3. de Mesy Bentley KL
  4. Boyce BF
  5. Gill AL
  6. Gill SR
  7. Nishitani K
  8. Ishikawa M
  9. Morita Y
  10. Ito H
  11. Bello-Irizarry SN
  12. Ninomiya M
  13. Brodell JD
  14. Lee CC
  15. Hao SP
  16. Oh I
  17. Xie C
  18. Awad HA
  19. Daiss JL
  20. Owen JR
  21. Kates SL
  22. Schwarz EM
  23. Muthukrishnan G
  Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy".; Bone research; Vol 7. 2019.
• 1. Oh I
  2. Muthukrishnan G
  3. Ninomiya MJ
  4. Brodell JD
  5. Smith BL
  6. Lee CC
  7. Gill SR
  8. Beck CA
  9. Schwarz EM
  10. Daiss JL
  Tracking Anti-Staphylococcus aureus Antibodies Produced In Vivo and Ex Vivo during Foot Salvage Therapy for Diabetic Foot Infections Reveals Prognostic Insights and Evidence of Diversified Humoral Immunity.; Infection and immunity. 2018 Oct 01.
• 1. Ricciardi BF
  2. Muthukrishnan G
  3. Masters E
  4. Ninomiya M
  5. Lee CC
  6. Schwarz EM
  Staphylococcus aureus Evasion of Host Immunity in the Setting of Prosthetic Joint Infection: Biofilm and Beyond.; Current reviews in musculoskeletal medicine. 2018 Jul 09.
• 1. Lawrance MF
  2. Muthukrishnan G
  3. Deichen J
  4. Deichen M
  5. Schaus J
  6. Cole AM
  7. Parkinson CL
  Genetic assessment of Staphylococcus aureus in an underreported locality: Ambulatory care clinic.; Journal of infection and public health; Vol 11(5), pp. 648-656. 2018 Apr 30.
• 1. Cole AL
  2. Muthukrishnan G
  3. Chong C
  4. Beavis A
  5. Eade CR
  6. Wood MP
  7. Deichen MG
  8. Cole AM
  Host innate inflammatory factors and staphylococcal protein A influence the duration of human Staphylococcus aureus nasal carriage.; Mucosal immunology; Vol 9(6), pp. 1537-1548. 2016 Feb 03.
• 1. Muthukrishnan G
  2. Lamers RP
  3. Ellis A
  4. Paramanandam V
  5. Persaud AB
  6. Tafur S
  7. Parkinson CL
  8. Cole AM
  Longitudinal genetic analyses of Staphylococcus aureus nasal carriage dynamics in a diverse population.; BMC infectious diseases; Vol 13, pp. 221. 2013 May 16.
• 1. Lamers RP
  2. Muthukrishnan G
  3. Castoe TA
  4. Tafur S
  5. Cole AM
  6. Parkinson CL
  Phylogenetic relationships among Staphylococcus species and refinement of cluster groups based on multilocus data.; BMC evolutionary biology; Vol 12, pp. 171. 2012 Sep 06.
• 1. Muthukrishnan G
  2. Quinn GA
  3. Lamers RP
  4. Diaz C
  5. Cole AL
  6. Chen S
  7. Cole AM
  Exoproteome of Staphylococcus aureus reveals putative determinants of nasal carriage.; Journal of proteome research; Vol 10(4), pp. 2064-78. 2011 Mar 07.
• 1. Lamers RP
  2. Stinnett JW
  3. Muthukrishnan G
  4. Parkinson CL
  5. Cole AM
  Evolutionary analyses of Staphylococcus aureus identify genetic relationships between nasal carriage and clinical isolates.; PloS one; Vol 6(1), pp. e16426. 2011 Jan 21.
• 1. Rajesh V
  2. Singamsetti VK
  3. Vidya S
  4. Gowrishankar M
  5. Elamaran M
  6. Tripathi J
  7. Radhika NB
  8. Kochar D
  9. Ranjan A
  10. Roy SK
  11. Das A
  Plasmodium falciparum: genetic polymorphism in apical membrane antigen-1 gene from Indian isolates.; Experimental parasitology; Vol 119(1), pp. 144-51. 2008 Feb 09.
• 1. Rajesh V
  2. Elamaran M
  3. Vidya S
  4. Gowrishankar M
  5. Kochar D
  6. Das A
  Plasmodium vivax: genetic diversity of the apical membrane antigen-1 (AMA-1) in isolates from India.; Experimental parasitology; Vol 116(3), pp. 252-6. 2007 Jan 23.