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Bacterial Cell Envelopes

The Pavelka laboratory studies the genetics and biochemistry of the cell envelopes of mycobacteria and Gram-negative bacteria. Our primary goals are to understand how bacterial cell envelopes are assembled and maintained in a variety of pathogenic bacteria. Our laboratory also develops genetic tools for our work in cell envelope biology.

Martin Pavelka, Ph.D.
Principal Investigator

Lab Members

Projects

Assembly of the mycobacterial peptidoglycan

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Publications

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1. Wirth KT
2. Loszko AF
3. Byrne MM
4. Wakeman DS
5. Pavelka MS
6. Baran TM
7. Wilson NA
Linking Antimicrobial Agent Resistance Profiles to Clinical Outcomes in Pediatric Perforated Appendicitis.; Surgical infections. 2026 Feb 25.
1. Wirth KT
2. Wang EY
3. Hawryluk DS
4. Byrne MM
5. Arca MJ
6. Wakeman DS
7. Pegoli W
8. Darcy DG
9. Pavelka MS
10. Wilson NA
11. Baran TM
Photodynamic therapy with methylene blue effectively kills antibiotic resistant bacteria from pediatric patients with perforated appendicitis.; Scientific reports. 2025 Dec 10.
1. Lin B
2. Woo S
3. Philbrick A
4. Bacsa J
5. Laskey E
6. Mehra N
7. Gondil VS
8. Mei JA
9. Jones G
10. Pavelka MS
11. Dziejman M
12. Shutter DA
13. Melander C
14. Perritt AM
15. Jakober R
16. Shen Y
17. Chang W-C
18. Quave CL
19. Dunman PM
20. Luedemann G
Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments.; mSphere. 2025 Sep 23.

Affiliations

Contact Us

Pavelka Laboratory
601 Elmwood Ave
Rochester, NY 14642

Martin_Pavelka@URMC.Rochester.edu

(585) 275-4670