URMC / Labs / White Lab / Publications

Recent Publications from the Patricia White Lab

1. Granato JM
2. Silver N
3. Hobbins A
4. Randolph J
5. Stout A
6. Gelbard HA
7. Gunnersen JM
8. Mackenzie SJ
9. White PM
10. Hammond JW
SEZ6L2 Loss Disrupts Motor Coordination, Cognitive Function, and Synaptic Connectivity.; bioRxiv : the preprint server for biology. 2026 Jan 01.
1. Piekna-Przybylska D
2. Na D
3. Zhang J
4. Baker C
5. Ashton JM
6. White PM
Corrigendum: Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation.; Frontiers in cellular neuroscience; Vol 18, pp. 1428589. 2024 May 24.
1. Na D
2. Zhang J
3. Beaulac HJ
4. Piekna-Przybylska D
5. Nicklas PR
6. Kiernan AE
7. White PM
Corrigendum: Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis.; Frontiers in neuroscience; Vol 17, pp. 1250244. 2023 Jul 18.
1. Na D
2. Zhang J
3. Beaulac HJ
4. Piekna-Przybylska D
5. Nicklas PR
6. Kiernan AE
7. White PM
Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis.; Frontiers in neuroscience; Vol 17, pp. 1106570. 2023 May 26.
1. Piekna-Przybylska D
2. Na D
3. Zhang J
4. Baker C
5. Ashton JM
6. White PM
Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation.; Frontiers in cellular neuroscience; Vol 16, pp. 1096872. 2023 Jan 06.
1. Gilels FA
2. Wang J
3. Bullen A
4. White PM
5. Kiernan AE
Deletion of the Notch ligand Jagged1 during cochlear maturation leads to inner hair cell defects and hearing loss.; Cell death & disease; Vol 13(11), pp. 971. 2022 Jan 18.
1. Na D
2. White PM
Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R.; Journal of visualized experiments : JoVE. 2022 Jan 09.
1. Beaulac HJ
2. Gilels F
3. Zhang J
4. Jeoung S
5. White PM
Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice.; Cell death & disease; Vol 12(7). 2021 Jul 07.
1. Patel S
2. Shah L
3. Dang N
4. Tan X
5. Almudevar A
6. White PM
SIRT3 promotes auditory function in young adult FVB/nJ mice but is dispensable for hearing recovery after noise exposure.; PloS one; Vol 15(7). 2020.
1. White PM
Genetic Susceptibility to Hearing Loss from Noise.; The Hearing Journal. 2019 Jan 01.
1. Zhang J
2. Wang Q
3. Abdul-Aziz D
4. Mattiacio J
5. Edge ASB
6. White PM
ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea.; The European journal of neuroscience. 2018 Sep 30.
1. Paquette ST
2. Dawes RP
3. Sundar IK
4. Rahman I
5. Brown EB
6. White PM
Chronic cigarette smoke exposure drives spiral ganglion neuron loss in mice.; Scientific reports; Vol 8(1). 2018 Apr 10.
1. Gilels F
2. Paquette ST
3. Beaulac HJ
4. Bullen A
5. White PM
Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure.; Scientific reports; Vol 7(1). 2017 Apr 21.
1. White PM
The Role of the Transcription Factor Foxo3 in Hearing Maintenance: Informed Speculation on a New Player in the Cochlea.; BioMed research international; Vol 2016. 2016.
1. Paquette ST
2. Gilels F
3. White PM
Noise exposure modulates cochlear inner hair cell ribbon volumes, correlating with changes in auditory measures in the FVB/nJ mouse.; Scientific reports; Vol 6. 2016.
1. Savoy-Burke G
2. Gilels FA
3. Pan W
4. Pratt D
5. Que J
6. Gan L
7. White PM
8. Kiernan AE
Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells.; PloS one; Vol 9(9). 2014.
1. Gilels F
2. Paquette ST
3. Zhang J
4. Rahman I
5. White PM
Mutation of Foxo3 causes adult onset auditory neuropathy and alters cochlear synapse architecture in mice.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 33(47). 2013 Nov 20.
1. White PM
2. Stone JS
3. Groves AK
4. Segil N
EGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammals.; Developmental biology; Vol 363(1). 2012 Mar 1.
1. White PM
2. Doetzlhofer A
3. Lee YS
4. Groves AK
5. Segil N
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells.; Nature; Vol 441(7096). 2006 Jun 22.
1. Doetzlhofer A
2. White P
3. Lee YS
4. Groves A
5. Segil N
Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea.; Brain research; Vol 1091(1). 2006 May 26.
1. Doetzlhofer A
2. White PM
3. Johnson JE
4. Segil N
5. Groves AK
In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme.; Developmental biology; Vol 272(2). 2004 Aug 15.
1. Lumpkin EA
2. Collisson T
3. Parab P
4. Omer-Abdalla A
5. Haeberle H
6. Chen P
7. Doetzlhofer A
8. White P
9. Groves A
10. Segil N
11. Johnson JE
Math1-driven GFP expression in the developing nervous system of transgenic mice.; Gene expression patterns : GEP; Vol 3(4). 2003 Aug.
1. White PM
2. Morrison SJ
3. Orimoto K
4. Kubu CJ
5. Verdi JM
6. Anderson DJ
Neural crest stem cells undergo cell-intrinsic developmental changes in sensitivity to instructive differentiation signals.; Neuron; Vol 29(1). 2001 Jan.
1. White PM
2. Anderson DJ
In vivo transplantation of mammalian neural crest cells into chick hosts reveals a new autonomic sublineage restriction.; Development (Cambridge, England); Vol 126(19). 1999 Oct.
1. Morrison SJ
2. White PM
3. Zock C
4. Anderson DJ
Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells.; Cell; Vol 96(5). 1999 Mar 5.
1. Novak TJ
2. White PM
3. Rothenberg EV
Regulatory anatomy of the murine interleukin-2 gene.; Nucleic acids research; Vol 18(15). 1990 Aug 11.