URMC / Labs / White Lab / Publications Publications Piekna-Przybylska DNa DZhang JBaker CAshton JMWhite PM Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation.; Frontiers in cellular neuroscience; Vol 16, pp. 1096872. 2023 Jan 06. Gilels FAWang JBullen AWhite PMKiernan AE Deletion of the Notch ligand Jagged1 during cochlear maturation leads to inner hair cell defects and hearing loss.; Cell death & disease; Vol 13(11), pp. 971. 2022 Jan 18. Na DWhite PM Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R.; Journal of visualized experiments : JoVE. 2022 Jan 09. Beaulac HJGilels FZhang JJeoung SWhite PM Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice.; Cell death & disease; Vol 12(7). 2021 Jul 07. Patel SShah LDang NTan XAlmudevar AWhite PM SIRT3 promotes auditory function in young adult FVB/nJ mice but is dispensable for hearing recovery after noise exposure.; PloS one; Vol 15(7). 2020. White PM Genetic Susceptibility to Hearing Loss from Noise.; The Hearing Journal. 2019 Jan 01. Zhang JWang QAbdul-Aziz DMattiacio JEdge ASBWhite PM ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea.; The European journal of neuroscience. 2018 Sep 30. Paquette STDawes RPSundar IKRahman IBrown EBWhite PM Chronic cigarette smoke exposure drives spiral ganglion neuron loss in mice.; Scientific reports; Vol 8(1). 2018 Apr 10. Gilels FPaquette STBeaulac HJBullen AWhite PM Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure.; Scientific reports; Vol 7(1). 2017 Apr 21. White PM The Role of the Transcription Factor Foxo3 in Hearing Maintenance: Informed Speculation on a New Player in the Cochlea.; BioMed research international; Vol 2016. 2016. Paquette STGilels FWhite PM Noise exposure modulates cochlear inner hair cell ribbon volumes, correlating with changes in auditory measures in the FVB/nJ mouse.; Scientific reports; Vol 6. 2016. Savoy-Burke GGilels FAPan WPratt DQue JGan LWhite PMKiernan AE Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells.; PloS one; Vol 9(9). 2014. Gilels FPaquette STZhang JRahman IWhite PM Mutation of Foxo3 causes adult onset auditory neuropathy and alters cochlear synapse architecture in mice.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 33(47). 2013 Nov 20. White PMStone JSGroves AKSegil N EGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammals.; Developmental biology; Vol 363(1). 2012 Mar 1. White PMDoetzlhofer ALee YSGroves AKSegil N Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells.; Nature; Vol 441(7096). 2006 Jun 22. Doetzlhofer AWhite PLee YSGroves ASegil N Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea.; Brain research; Vol 1091(1). 2006 May 26. Doetzlhofer AWhite PMJohnson JESegil NGroves AK In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme.; Developmental biology; Vol 272(2). 2004 Aug 15. Lumpkin EACollisson TParab POmer-Abdalla AHaeberle HChen PDoetzlhofer AWhite PGroves ASegil NJohnson JE Math1-driven GFP expression in the developing nervous system of transgenic mice.; Gene expression patterns : GEP; Vol 3(4). 2003 Aug. White PMMorrison SJOrimoto KKubu CJVerdi JMAnderson DJ Neural crest stem cells undergo cell-intrinsic developmental changes in sensitivity to instructive differentiation signals.; Neuron; Vol 29(1). 2001 Jan. White PMAnderson DJ In vivo transplantation of mammalian neural crest cells into chick hosts reveals a new autonomic sublineage restriction.; Development (Cambridge, England); Vol 126(19). 1999 Oct. Morrison SJWhite PMZock CAnderson DJ Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells.; Cell; Vol 96(5). 1999 Mar 5. Novak TJWhite PMRothenberg EV Regulatory anatomy of the murine interleukin-2 gene.; Nucleic acids research; Vol 18(15). 1990 Aug 11.