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Transitional Cell States: Decision-Making at the Crossroad of Development and Disease

Wellington V. Cardoso, MD, PhD - Professor of Medicine and Genetics and Development, Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University Medical Center

Wellington V. Cardoso, MD, PhDWellington V. Cardoso, MD, PhD is a Professor of Medicine and Genetics & Development, Associate Vice-Chair for Research & Director of Interdisciplinary Programs at the Department of Medicine, Columbia University. In his tenure at Columbia he established and directed the Columbia Center for Human Development (CCHD), a multi-disciplinary research hub for studies on stem cell, organ development and the developmental basis of human diseases. Dr. Cardoso’s research focuses on lung development and regeneration, particularly the understanding of the origin, organization and behavior of the lung stem cell compartment during development and repair. Work from his lab pioneered discoveries on the roles of FGFs, Notch, Hippo-Yap, and retinoids in the normal lung, providing fundamental insights into the pathogenesis of developmental abnormalities and human conditions, such as COPD, asthma and neuroendocrine hyperplasias. Recent contributions include the characterization of viral-host interactions and drug targeting in human airways, the establishment of innovative technology for generation of lungs in vivo by blastocyst complementation, the development of a non-invasive platform for functional analysis of human newborn airway stem cells, and the identification and functional characterization of epithelial progenitors undergoing a transitional cell state conserved during lung morphogenesis and regeneration in mice and humans.

Sponsored by NIH T32HL171029 Multidisciplinary Training in Pulmonary Research (PI’s: S. Georas and M. O’Reilly)

(*In-person attendance preferred; for Zoom link email Nicole_Cruz@urmc.rochester.edu)

 Jan 22, 2026 @ 12:00 p.m.
 School of Medicine and Dentistry | Adolph Auditorium, Lower (1-7619)

(Zoom link available on request*)
Host: Pulmonary T32 Seminar Series