Biography
Dr. Mohile completed his residency training at Northwestern University, followed by a fellowship in Neuro-oncology at Memorial Sloan-Kettering Cancer Center. He is certified in Neurology and Neuro-oncology. In 2007, he joined the neurology department at the University of Rochester where he built and fostered the neuro-oncology division and multi-disciplinary brain tumor program. His mission is to teach, elevate clinical care and perform research that extends and improves the lives of patients with brain tumors.
Dr. Mohile sees patients with primary and metastatic brain tumors and is involved in administering chemotherapy, treating seizures and managing side effects of brain tumors and brain tumor therapy. In addition, he does consultations on patients with neurologic complications of cancer or cancer treatments.
Professional Background
Nimish Mohile, MD, MS, FAAN is a Professor of Neurology and Oncology at the University of Rochester and the Ann Aresty Camhi Professor of Neurology. He serves as the Associate Chair for Academic Affairs, Neuro-oncology Division Chief and leads the Neuro-oncology service line. He is a UCNS fellowship program director, serves on the UCNS Certification committee, chairs the American Society of Clinical Oncology Glioma Guidelines Panel and is currently the Chair of the AAN section for Neuro-oncology.
As an Associate Chair for Academic Affairs, he has spearheaded innovative programs that emphasize personal values, identity and reflective work in the professional development of faculty, administrative staff, advanced practice providers and residents. He also directs departmental leadership programs for residents and faculty to develop leadership skills, implement change and develop resilient teams. At the American Academy of Neurology, he serves as the Physician Lead for the Transforming Leaders Program.
Dr. Mohile aspires to help organizations transform into multicultural, antiracist and equitable entities. He is an advocate for incorporating principles of inclusion, diversity, equity, antiracism and social justice into the profession of neurology. He is the Chair of the AAN Diversity Officer’s Group.
Research
His research focuses on developing and testing therapeutic and supportive care interventions to improve and extend the lives of patients with malignant gliomas. He has authored over 50 peer-reviewed publications. He is currently the principal investigator of several industry-sponsored, investigator-initiated and NCI- funded clinical trials. He has developed a body of work that explores the burdens experienced by patients with brain tumors and caregivers, related to hospitalizations, seizures, decision-making and end of life care.
Awards
2015
A. B. Baker Teacher Recognition Award
Sponsor: American Academy of Neurology
2011
SWOG Travel Award Recipient
Sponsor: Southwest Oncology Group
2011
Neurology Faculty Teaching Award
Sponsor: University of Rochester
Location: Rochester, NY
2009
American Neurological Association Junior Academic Scholarship Award
2007
American Society of Clinical Oncology Foundation Merit Award
Sponsor: American Society of Clinical Oncology Foundation
2004
Graduate Medical Education Award for excellence in teaching medical students
2004
AAN Resident Annual Meeting Scholarship
Sponsor: American Academy of Neurology
1996 - 2000
Dean's List
Sponsor: St George's University
Location: Grenada, WI
1994
Dean's List
Sponsor: Duke University
Location: Durham, NC
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Clinical Trials
EF-32: Pivotal, Randomized, Open-Label Study of Optune® (Tumor Treating Fields, 200kHz) Concomitant With Radiation Therapy and Temozolomide for the Treatment of Newly Diagnosed Glioblastoma
Lead Researcher: Nimish A Mohile
To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. In both arms, Optune® and maintenance temozolomide are continued following radiation therapy.
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Genomically-Guided Treatment Trial in Brain Metastases
Lead Researcher: Nimish A Mohile
This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK or PI3K. Medications that target these genes such as abemaciclib, paxalisib, and entrectinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Genetic testing may help doctors tailor treatment for each mutation.
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Publications
Journal Articles
2/15/2023
Hardy SJ, Finkelstein AJ, Tivarus M, Culakova E, Mohile N, Weber M, Lin E, Zhong J, Usuki K, Schifitto G, Milano M, Janelsins-Benton MC. "Cognitive and neuroimaging outcomes in individuals with benign and low-grade brain tumours receiving radiotherapy: a protocol for a prospective cohort study." BMJ open.. 2023 Feb 15; 13(2):e066458. Epub 2023 Feb 15.
5/13/2022
Schiff D, Messersmith H, Brastianos PK, Brown PD, Burri S, Dunn IF, Gaspar LE, Gondi V, Jordan JT, Maues J, Mohile N, Redjal N, Stevens GHJ, Sulman EP, van den Bent M, Wallace HJ, Zadeh G, Vogelbaum MA. "Radiation Therapy for Brain Metastases: ASCO Guideline Endorsement of ASTRO Guideline." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2022 May 13; :JCO2200333. Epub 2022 May 13.
4/2022
Strowd RE, Dunbar EM, Gan HK, Kurz S, Jordan JT, Mandel JJ, Mohile NA, Nevel KS, Taylor JW, Ullrich NJ, Welch MR, Wasilewski A, Mrugala MM. "Practical guidance for telemedicine use in neuro-oncology." Neuro-oncology practice.. 2022 Apr; 9(2):91-104. Epub 2022 Jan 17.
Books & Chapters
2007
Chapter Title: Principles of Chemotherapy
Book Title: Brain Tumors: Practical Guide to Diagnosis and Treatment
Author List: Abrey LE and Mohile NA
Edited By: Baehring J, Piepmeier J
Published By: Informa Health Care, USA 2007 in New York
2006
Chapter Title: Chemotherapy of Neuronal Tumors
Book Title: Handbook of Brain Tumor Chemotherapy
Author List: Mohile, N.A.; Raizer, J.J.
Edited By: Newton, H.B.
Published By: Elsevier 2006 in Amsterdam: Boston
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