Publications
Showing all 116 journal articles & 10 books available
Journal Articles
6/2022
Khairnar R, DeMora L, Sandler HM, Lee WR, Villalonga-Olives E, Mullins CD, Palumbo FB, Bruner DW, Shaya FT, Bentzen SM, Shah AB, Malone S, Michalski JM, Dayes IS, Seaward SA, Albert M, Currey AD, Pisansky TM, Chen Y, Horwitz EM, DeNittis AS, Feng F, Mishra MV. "Methodological Comparison of Mapping the Expanded Prostate Cancer Index Composite to EuroQoL-5D-3L Using Cross-Sectional and Longitudinal Data: Secondary Analysis of NRG/RTOG 0415." JCO clinical cancer informatics.. 2022 Jun; 6:e2100188.
2022
Bigelow EO; Harris J; Fakhry C; Gillison ML; Nguyen-Tân PF; Rosenthal DI; Frank SJ; Nair SG; Bahig H; Ridge JA; Caudell J; Donaldson C; Clifford BT; Shenouda G; Birrer MJ; Chen Y; Le QT. "Risk stratification after recurrence of human papillomavirus (HPV)-related and non-HPV-related oropharyngeal cancer: Secondary analysis of NRG Oncology RTOG 0129 and 0522". Head Neck. 2022; 44(1): 158-167.
2022
Chen F; Chen X; Ren Y; Weng G; Keng PC; Chen Y; Lee SO. "Retraction Note: Radiation-induced glucocorticoid receptor promotes CD44?+?prostate cancer stem cell growth through activation of SGK1-Wnt/?-catenin signaling". J Mol Med (Berl). 2022; 100(1): 149.
2022
Kerns SL; Amidon Morlang A; Lee SM; Peterson DR; Marples B; Zhang H; Bylund K; Rosenzweig D; Hall W; De Ruyck K; Rosenstein BS; Stock RG; Gómez-Caamaño A; Vega A; Sosa-Fajardo P; Taboada-Valladares B; Aguado-Barrera ME; Parker C; Veldeman L; Fonteyne V; Bultijnck R; Talbot CJ; Symonds RP; Johnson K; Rattay T; Webb A; Lambrecht M; de Ruysscher D; Vanneste B; Choudhury A; Elliott RM; Sperk E; Herskind C; Veldwijk MR; Rancati T; Avuzzi B; Valdagni R; Azria D; Farcy Jacquet MP...Chen Y; et al. "Use of angiotensin converting enzyme inhibitors is associated with reduced risk of late bladder toxicity following radiotherapy for prostate cancer". Radiother Oncol. 2022; 168: 75-82.
2022
Zhang H; Yang H; Bandyopadhyay S; Milano MT; Fung C; Messing EM; Chen Y. "Increased risk of high-grade prostate cancer among testicular cancer survivors". PLoS One. 2022; 17(2): e0263573.
10/2021
Zhu R, Yang X, Xue X, Shen M, Chen F, Chen X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. "Retraction notice to "Neuroendocrine differentiation contributes to radioresistance development and metastatic potential increase in non-small cell lung cancer" [Biochim. Biophys. Acta, Mol. Cell Res. Volume 1865, Issue 12, December 2018, Pages 1878-1890]." Biochimica et biophysica acta. Molecular cell research.. 2021 Oct; 1868(11):119097. Epub 2021 Aug 07.
8/2021
Shen M, Tsai Y, Zhu R, Keng PC, Chen Y, Chen Y, Lee SO. "Retraction notice to "FASN-TGF-?1-PD-L1 axis contributes to the development of resistance to NK cell cytotoxicity of cisplatin-resistant lung cancer cells" [BBA - Molecular and Cell Biology of Lipids 1863/3 (March 2018) 313-322]." Biochimica et biophysica acta. Molecular and cell biology of lipids.. 2021 Aug; 1866(8):158946. Epub 2021 Apr 28.
2021
Bitterman DS; Winter KA; Hong TS; Fuchs CS; Regine WF; Abrams RA; Safran H; Hoffman JP; Benson AB; Kasunic T; Mulcahy M; Strauss JF; DiPetrillo T; Stella PJ; Chen Y; Plastaras JP; Crane CH. "Impact of Diabetes and Insulin Use on Prognosis in Patients With Resected Pancreatic Cancer: An Ancillary Analysis of NRG Oncology RTOG 9704". Int J Radiat Oncol Biol Phys. 2021; 109(1): 201-211.
2021
Khairnar R; Pugh SL; Sandler HM; Lee WR; Villalonga Olives E; Mullins CD; Palumbo FB; Bruner DW; Shaya FT; Bentzen SM; Shah AB; Malone SC; Michalski JM; Dayes IS; Seaward SA; Albert M; Currey AD; Pisansky TM; Chen Y; Horwitz EM; DeNittis AS; Feng FY; Mishra MV. "Mapping expanded prostate cancer index composite to EQ5D utilities to inform economic evaluations in prostate cancer: secondary analysis of NRG/RTOG 0415". PLoS One. 2021; 16(4): e0249123.
2021
Webster M; Tanny S; Joyce N; Herman A; Chen Y; Milano M; Usuki K; Constine L; Singh D; Yeo I. "New dosimetric guidelines for linear Boltzmann transport equations through comparative evaluation of stereotactic body radiation therapy for lung treatment planning". J Appl Clin Med Phys. 2021; 22(12): 115-124.
2021
Zhang H, Doucette C, Yang H, Bandyopadhyay S, Grossman CE, Messing EM, Chen Y. "Risk of adverse pathological features for intermediate risk prostate cancer: Clinical implications for definitive radiation therapy." PloS one.. 2021 16(7):e0253936. Epub 2021 Jul 15.
6/1/2020
Xu L, Shen M, Chen X, Yang DR, Tsai Y, Keng PC, Lee SO, Chen Y. "Corrigendum to "In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells"[Exp Cell Res 364 (2018) 113-123]." Experimental cell research.. 2020 Jun 1; 391(1):112006. Epub 2020 Apr 21.
3/2020
Reyngold M, Winter KA, Regine WF, Abrams RA, Safran H, Hoffman JP, Mowat RB, Hayes JP, Kessel IL, DiPetrillo T, Narayan S, Chen Y, Ben-Josef E, Delouya G, Suh JH, Meyer J, Haddock MG, Feldman M, Gaur R, Yost K, Peterson RA, Sherr DL, Moughan J, Crane CH. "Marital Status and Overall Survival in Patients with Resectable Pancreatic Cancer: Results of an Ancillary Analysis of NRG Oncology/RTOG 9704." The oncologist.. 2020 Mar; 25(3):e477-e483. Epub 2019 Dec 16.
2020
Torous DK; Avlasevich SL; Khattab MG; Baig A; Saubermann LJ; Chen Y; Bemis JC; Lovell DP; Walker VE; MacGregor JT; Dertinger SD. "Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation". Environ Mol Mutagen. 2020; 61(8): 807-819.
2020
Chen D; Chou FJ; Chen Y; Tian H; Wang Y; You B; Niu Y; Huang CP; Yeh S; Xing N; Chang C. "Targeting the radiation-induced TR4 nuclear receptor-mediated QKI/circZEB1/miR-141-3p/ZEB1 signaling increases prostate cancer radiosensitivity". Cancer Lett. 2020; 495: 100-111.
2020
Shen M; Chen Y; Xu L; Zhu R; Xue X; Tsai Y; Keng PC; Lee SO; Chen Y. "[Corrigendum] Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells". Int J Oncol. 2020; 57(4): 1072-1073.
6/2019
Thor M, Deasy JO, Paulus R, Robert Lee W, Amin MB, Bruner DW, Low DA, Shah AB, Malone SC, Michalski JM, Dayes IS, Seaward SA, Gore EM, Albert M, Pisansky TM, Faria SL, Chen Y, Koontz BF, Swanson GP, Pugh SL, Sandler HM. "Tolerance doses for late adverse events after hypofractionated radiotherapy for prostate cancer on trial NRG Oncology/RTOG 0415." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.. 2019 Jun; 135:19-24. Epub 2019 Mar 05.
1/1/2019
Zhu R, Xue X, Shen M, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. "NF?B and TNF? as individual key molecules associated with the cisplatin-resistance and radioresistance of lung cancer." Experimental cell research.. 2019 Jan 1; 374(1):181-188. Epub 2018 Dec 01.
2019
Chou FJ; Chen Y; Chen D; Niu Y; Li G; Keng P; Yeh S; Chang C. "Preclinical study using androgen receptor (AR) degradation enhancer to increase radiotherapy efficacy via targeting radiation-increased AR to better suppress prostate cancer progression". EBioMedicine. 2019; 40: 504-516.
2019
Dawson LA; Winter KA; Katz AW; Schell MC; Brierley J; Chen Y; Kopek N; Crane CH, Willett CG. "NRG Oncology/RTOG 0438: A Phase I Trial of Highly Conformal Radiation Therapy for Liver Metastases". Pract Radiat Oncol. 2019; 9(4): e386-e393.
2019
Sun A; Hu C; Wong SJ; Gore E; Videtic G; Dutta S; Suntharalingam M; Chen Y; Gaspar LE; Choy H. "Prophylactic cranial irradiation vs observation in patients with locally advanced non-small cell lung cancer: a long-term update of the NRG Oncology/RTOG 0214 Phase 3 randomized clinical trial". JAMA Oncol. 2019; 5(6): 847-855.
2019
Bruner DW; Pugh SL; Lee WR; Dignam JJ; Low D; Swanson GP; Shah AB; Malone S; Michalski JM; Dayes IS; Seaward SA; Nguyen PL; Hall WA; Pisansky TM; Chen Y; Sandler HM; Movsas B. "Quality of Life in Patients With Low-Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy: A Phase 3 Randomized Clinical Trial". JAMA Oncol. 2019; 5(5): 664-670.
2019
Singh D; Chen Y; Cummings MA; Milano MT. "Inoperable pulmonary carcinoid tumors: local control rates with stereotactic body radiotherapy/hypofractionated RT with image-guided radiotherapy". Clin Lung Cancer. 2019; 20(3): e284-e290.
12/2018
Zhu R, Yang X, Xue X, Shen M, Chen F, Chen X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. "Neuroendocrine differentiation contributes to radioresistance development and metastatic potential increase in non-small cell lung cancer." Biochimica et biophysica acta. Molecular cell research.. 2018 Dec; 1865(12):1878-1890. Epub 2018 Sep 15.
11/2018
Kerns S, Chuang KH, Hall W, Werner Z, Chen Y, Ostrer H, West C, Rosenstein B. "Radiation biology and oncology in the genomic era." The British journal of radiology.. 2018 Nov; 91(1091):20170949. Epub 2018 Jun 14.
11/2018
Cummings MA, Ma SJ, Hermann G, Serra L, Syed Y, Malhotra HK, Chen Y, Milano MT, Gomez-Suescun JA, Singh DP, Singh AK. "Comparison of Single- and Five-fraction Regimens of Stereotactic Body Radiation Therapy for Peripheral Early-stage Non-small-cell Lung Cancer: A Two-institution Propensity-matched Analysis." Clinical lung cancer.. 2018 Nov; 19(6):511-517. Epub 2018 Jul 30.
7/1/2018
Cheng TD, Darke AK, Redman MW, Zirpoli GR, Davis W, Payne Ondracek R, Bshara W, Omilian AR, Kratzke R, Reid ME, Molina JR, Kolesar JM, Chen Y, MacRae RM, Moon J, Mack P, Gandara DR, Kelly K, Santella RM, Albain KS, Ambrosone CB. "Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424)." Journal of the National Cancer Institute.. 2018 Jul 1; 110(7):734-742.
7/2018
Shen M, Chen Y, Xu L, Zhu R, Xue X, Tsai Y, Keng PC, Lee SO, Chen Y. "Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells." International journal of oncology.. 2018 Jul; 53(1):317-328. Epub 2018 May 04.
5/2018
Ma SJ, Cummings M, Serra LM, Syed YA, Hermann GM, Chen Y, Milano MT, Singh AK, Gomez-Suescun JA, Singh DP. "Three- Versus Five-Fraction Regimens of Stereotactic Body Radiotherapy for Peripheral Early-Stage Non-Small-Cell Lung Cancer: A Two-Institution Propensity Score-Matched Analysis." Clinical lung cancer.. 2018 May; 19(3):e297-e302. Epub 2017 Nov 26.
4/2018
Xu L, Shen M, Chen X, Zhu R, Yang DR, Tsai Y, Keng PC, Chen Y, Lee SO. "Adipocytes affect castration-resistant prostate cancer cells to develop the resistance to cytotoxic action of NK cells with alterations of PD-L1/NKG2D ligand levels in tumor cells." The Prostate.. 2018 Apr; 78(5):353-364. Epub 2018 Jan 12.
3/1/2018
Xu L, Shen M, Chen X, Yang DR, Tsai Y, Keng PC, Lee SO, Chen Y. "In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells." Experimental cell research.. 2018 Mar 1; 364(1):113-123. Epub 2018 Feb 01.
3/2018
Xu L, Chen X, Shen M, Yang DR, Fang L, Weng G, Tsai Y, Keng PC, Chen Y, Lee SO. "Inhibition of IL-6-JAK/Stat3 signaling in castration-resistant prostate cancer cells enhances the NK cell-mediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels." Molecular oncology.. 2018 Mar; 12(3):269-286. Epub 2018 Jan 24.
3/2018
Shen M, Tsai Y, Zhu R, Keng PC, Chen Y, Chen Y, Lee SO. "FASN-TGF-?1-PD-L1 axis contributes to the development of resistance to NK cell cytotoxicity of cisplatin-resistant lung cancer cells." Biochimica et biophysica acta. Molecular and cell biology of lipids.. 2018 Mar; 1863(3):313-322. Epub 2018 Jan 03.
3/2018
Ali AN, Zhang P, Yung WKA, Chen Y, Movsas B, Urtasun RC, Jones CU, Choi KN, Michalski JM, Fischbach AJ, Markoe AM, Schultz CJ, Penas-Prado M, Garg MK, Hartford AC, Kim HE, Won M, Curran WJ. "NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients." Journal of neuro-oncology.. 2018 Mar; 137(1):39-47. Epub 2018 Feb 05.
2/1/2018
Anderson CM, Sonis ST, Lee CM, Adkins D, Allen BG, Sun W, Agarwala SS, Venigalla ML, Chen Y, Zhen W, Mould DR, Holmlund JT, Brill JM, Buatti JM. "Phase 1b/2a Trial of the Superoxide Dismutase Mimetic GC4419 to Reduce Chemoradiotherapy-Induced Oral Mucositis in Patients With Oral Cavity or Oropharyngeal Carcinoma." International journal of radiation oncology, biology, physics.. 2018 Feb 1; 100(2):427-435. Epub 2017 Oct 16.
1/2018
Qiu H, Katz AW, Chowdhry AK, Usuki KY, Singh DP, Metcalfe S, Cheruvu P, Chen Y, Okunieff P, Milano MT. "Stereotactic Body Radiotherapy for Lung Metastases from Colorectal Cancer: Prognostic Factors for Disease Control and Survival." American journal of clinical oncology.. 2018 Jan; 41(1):53-58.
2018
Regine WF, Winter K, Abrams RA, Safran H, Kessel IL, Chen Y, Fugazzi JA, Donnelly ED, DiPetrillo TA, Narayan S, Plastaras JP, Gaur R, Delouya G, Suh JH, Meyer JE, Haddock MG, Didolkar MS, Padula GDA, Johnson D, Hoffman JP, Crane CH. "Postresection CA19-9 and margin status as predictors of recurrence after adjuvant treatment for pancreatic carcinoma: Analysis of NRG oncology RTOG trial 9704." Advances in radiation oncology.. 2018 3(2):154-162. Epub 2018 Feb 09.
10/6/2017
Shen MJ, Xu LJ, Yang L, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. "Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway." Oncotarget.. 2017 Oct 6; 8(46):80506-80520. Epub 2017 Jul 12.
9/2017
Edelman MJ, Hu C, Le QT, Donington JS, D'Souza WD, Dicker AP, Loo BW, Gore EM, Videtic GMM, Evans NR, Leach JW, Diehn M, Feigenberg SJ, Chen Y, Paulus R, Bradley JD. "Randomized Phase II Study of Preoperative Chemoradiotherapy ± Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer: NRG Oncology RTOG 0839." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2017 Sep; 12(9):1413-1420. Epub 2017 Jun 16.
8/11/2017
Yang L, Shen M, Xu LJ, Yang X, Tsai Y, Keng PC, Chen Y, Lee SO. "Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition." Scientific reports.. 2017 Aug 11; 7(1):7958. Epub 2017 Aug 11.
8/3/2017
Zhang F, Shen M, Yang L, Yang X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. "Simultaneous targeting of ATM and Mcl-1 increases cisplatin sensitivity of cisplatin-resistant non-small cell lung cancer." Cancer biology & therapy.. 2017 Aug 3; 18(8):606-615. Epub 2017 Jul 07.
6/1/2017
Olsen JR, Moughan J, Myerson R, Abitbol A, Doncals DE, Johnson D, Schefter TE, Chen Y, Fisher B, Michalski J, Narayan S, Chang A, Crane CH, Kachnic L. "Predictors of Radiation Therapy-Related Gastrointestinal Toxicity From Anal Cancer Dose-Painted Intensity Modulated Radiation Therapy: Secondary Analysis of NRG Oncology RTOG 0529." International journal of radiation oncology, biology, physics.. 2017 Jun 1; 98(2):400-408. Epub 2017 Feb 13.
1/2017
Wang X, Yang X, Tsai Y, Yang L, Chuang KH, Keng PC, Lee SO, Chen Y. "IL-6 Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 in Non-small Cell Lung Cancer." Radiation research.. 2017 Jan; 187(1):50-59. Epub 2017 Jan 05.
2017
Kong F-M; Zhao L; Wang L; Chen Y; Hu J; Fu X; Bai C; Wang L; Lawrence TS; Anscher MS; Dicker A; Okunieff P. "Ensuring sample quality for blood biomarker studies in clinical trials: a multicenter international study for plasma and serum sample preparation". Transl Lung Cancer Res. 2017; 6: 625-634.
7/10/2016
Lee WR, Dignam JJ, Amin MB, Bruner DW, Low D, Swanson GP, Shah AB, D'Souza DP, Michalski JM, Dayes IS, Seaward SA, Hall WA, Nguyen PL, Pisansky TM, Faria SL, Chen Y, Koontz BF, Paulus R, Sandler HM. "Randomized Phase III Noninferiority Study Comparing Two Radiotherapy Fractionation Schedules in Patients With Low-Risk Prostate Cancer." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2016 Jul 10; 34(20):2325-32. Epub 2016 Apr 04.
6/2016
Zhang F, Duan S, Tsai Y, Keng P, Chen Y, Lee SO, Chen Y. "Cisplatin treatment increases stemness through upregulation of hypoxia-inducible factors by interleukin-6 in non-small cell lung cancer." Cancer science.. 2016 Jun; 107(6):746-54. Epub 2016 May 03.
2/9/2016
Lee SO, Yang X, Duan S, Tsai Y, Strojny LR, Keng P, Chen Y. "IL-6 promotes growth and epithelial-mesenchymal transition of CD133+ cells of non-small cell lung cancer." Oncotarget.. 2016 Feb 9; 7(6):6626-38.
2016
Yang L; Zhang F; Wang X; Tsai Y; Chuang KH; Keng PC; Lee SO; Chen Y. "A FASN-TGF-?1-FASN regulatory loop contributes to high EMT/metastatic potential of cisplatin-resistant non-small cell lung cancer". Oncotarget. 2016; 7(34): 55543-55554.
2016
Lin H, Chen Y, Shi A, Pandya KJ, Yu R, Yuan Y, Li J, Li H, Wang Y, Xia T, Feng L, Ma H, Geng J, Zhu G. "Phase 3 Randomized Low-Dose Paclitaxel Chemoradiotherapy Study for Locally Advanced Non-Small Cell Lung Cancer." Frontiers in oncology.. 2016 6:260. Epub 2016 Dec 20.
11/14/2015
Chen Y, Zhang F, Tsai Y, Yang X, Yang L, Duan S, Wang X, Keng P, Lee SO. "IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation." Radiation oncology.. 2015 Nov 14; 10:227. Epub 2015 Nov 14.
9/29/2015
Duan S, Tsai Y, Keng P, Chen Y, Lee SO, Chen Y. "IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules." Oncotarget.. 2015 Sep 29; 6(29):27651-60.
6/1/2015
Constine LS, Chen Y. "Philip Rubin, MD, FASTRO: Reflections on a Radiation Oncology Pioneer." International journal of radiation oncology, biology, physics.. 2015 Jun 1; 92(2):193-5.
5/2015
Dertinger SD, Avlasevich SL, Bemis JC, Chen Y, MacGregor JT. "Human erythrocyte PIG-A assay: an easily monitored index of gene mutation requiring low volume blood samples." Environmental and molecular mutagenesis.. 2015 May; 56(4):366-77. Epub 2014 Nov 20.
4/2015
Singh DP, Bylund KC, Matloubieh A, Mazloom A, Gray A, Sidhu R, Barrette L, Chen Y. "Is there a subset of patients with recurrent cancer in the vagina who are not candidates for interstitial brachytherapy that can be treated with multichannel vaginal brachytherapy using graphic optimization?" Journal of contemporary brachytherapy.. 2015 Apr; 7(2):135-41. Epub 2015 Apr 28.
2015
Singh D; Chen Y; Bergsma DP; Usuki KY; Dhakal S; Hare MZ; Joyce N; Smudzin T; Rosenzweig D; Schell MC; Milano MT. "Local control rates with five fractions of stereotactic body radiotherapy for primary lung tumors: a single institution experience of 153 consecutive patients". Transl Cancer Res. 2015; 4(4): 332-339.
4/2014
Singh D, Chen Y, Hare MZ, Usuki KY, Zhang H, Lundquist T, Joyce N, Schell MC, Milano MT. "Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung." Journal of thoracic disease.. 2014 Apr; 6(4):369-74.
1/2014
Chen Y, Nowak I, Huang J, Keng PC, Sun H, Xu H, Wei G, Lee SO. "Erk/MAP kinase signaling pathway and neuroendocrine differentiation of non-small-cell lung cancer." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2014 Jan; 9(1):50-8.
2014
Qiu H; Hare M; Chen Y. "A case report of long-term survival of metastatic extraskeletal myxoid chondrosarcoma treated with surgery and hypofractionated radiotherapy". J Radiother Pract. 2014; 13: 493-497.
12/2013
Liesveld JL, Phillips GL, Becker M, Constine LS, Friedberg J, Andolina JR, Milner LA, Debolt J, Smudzin T, Hyrien O, Erickson-Miller CL, Johnson BM, Dawson KL, Chen Y. "A phase 1 trial of eltrombopag in patients undergoing stem cell transplantation after total body irradiation." Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2013 Dec; 19(12):1745-52. Epub 2013 Oct 08.
9/2013
Huang CK, Lai KP, Luo J, Tsai MY, Kang HY, Chen Y, Lee SO, Chang C. "Loss of androgen receptor promotes adipogenesis but suppresses osteogenesis in bone marrow stromal cells." Stem cell research.. 2013 Sep; 11(2):938-50. Epub 2013 Jun 10.
6/7/2013
Yang DR, Ding XF, Luo J, Shan YX, Wang R, Lin SJ, Li G, Huang CK, Zhu J, Chen Y, Lee SO, Chang C. "Increased chemosensitivity via targeting testicular nuclear receptor 4 (TR4)-Oct4-interleukin 1 receptor antagonist (IL1Ra) axis in prostate cancer CD133+ stem/progenitor cells to battle prostate cancer." The Journal of biological chemistry.. 2013 Jun 7; 288(23):16476-83. Epub 2013 Apr 22.
5/2013
Liesveld J, Pawlowski J, Chen R, Hyrien O, Debolt J, Becker M, Phillips G, Chen Y. "Clinical factors affecting engraftment and transfusion needs in SCT: a single-center retrospective analysis." Bone marrow transplantation.. 2013 May; 48(5):691-7. Epub 2012 Oct 22.
2013
Chen Y, Moon J, Pandya KJ, Lau DH, Kelly K, Hirsch FR, Gaspar LE, Redman M, Gandara DR. "A Pilot Study (SWOG S0429) of Weekly Cetuximab and Chest Radiotherapy for Poor-Risk Stage III Non-Small Cell Lung Cancer." Frontiers in oncology.. 2013 3:219. Epub 2013 Aug 28.
2013
Zhang H, Messing EM, Travis LB, Hyrien O, Chen R, Milano MT, Chen Y. "Age and Racial Differences among PSA-Detected (AJCC Stage?T1cN0M0) Prostate Cancer in the U.S.: A Population-Based Study of 70,345 Men." Frontiers in oncology.. 2013 3:312. Epub 2013 Dec 23.
12/2012
Milano MT, Peterson CR, Zhang H, Singh DP, Chen Y. "Second primary lung cancer after head and neck squamous cell cancer: population-based study of risk factors." Head & neck.. 2012 Dec; 34(12):1782-8. Epub 2012 Feb 09.
11/15/2012
Milano MT, Zhang H, Usuki KY, Singh DP, Chen Y. "Definitive radiotherapy for stage I nonsmall cell lung cancer: a population-based study of survival." Cancer.. 2012 Nov 15; 118(22):5572-9. Epub 2012 Apr 27.
9/2012
Sun H, Tsai Y, Nowak I, Liesveld J, Chen Y. "Eltrombopag, a thrombopoietin receptor agonist, enhances human umbilical cord blood hematopoietic stem/primitive progenitor cell expansion and promotes multi-lineage hematopoiesis." Stem cell research.. 2012 Sep; 9(2):77-86. Epub 2012 May 14.
7/2012
Reid R, Bennett JM, Becker M, Chen Y, Milner L, Phillips Ii GL, Liesveld J. "Use of eltrombopag, a thrombopoietin receptor agonist, in post-transplantation thrombocytopenia." American journal of hematology.. 2012 Jul; 87(7):743-5. Epub 2012 May 10.
3/1/2012
Zhang H, Travis LB, Chen R, Hyrien O, Milano MT, Newlands SD, Chen Y. "Impact of radiotherapy on laryngeal cancer survival: a population-based study of 13,808 US patients." Cancer.. 2012 Mar 1; 118(5):1276-87. Epub 2011 Jul 19.
1/2012
Schuette W, Krzakowski MJ, Massuti B, Otterson GA, Lizambri R, Wei H, Berger DP, Chen Y. "Randomized phase II study of palifermin for reducing dysphagia in patients receiving concurrent chemoradiotherapy for locally advanced unresectable non-small cell lung cancer." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2012 Jan; 7(1):157-64.
8/1/2011
Chen Y, Pandya KJ, Hyrien O, Keng PC, Smudzin T, Anderson J, Qazi R, Smith B, Watson TJ, Feins RH, Johnstone DW. "Preclinical and pilot clinical studies of docetaxel chemoradiation for Stage III non-small-cell lung cancer." International journal of radiation oncology, biology, physics.. 2011 Aug 1; 80(5):1358-64. Epub 2010 Aug 12.
7/10/2011
Le QT, Kim HE, Schneider CJ, Muraközy G, Skladowski K, Reinisch S, Chen Y, Hickey M, Mo M, Chen MG, Berger D, Lizambri R, Henke M. "Palifermin reduces severe mucositis in definitive chemoradiotherapy of locally advanced head and neck cancer: a randomized, placebo-controlled study." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2011 Jul 10; 29(20):2808-14. Epub 2011 Jun 13.
6/30/2011
Cheruvu P, Metcalfe SK, Metcalfe J, Chen Y, Okunieff P, Milano MT. "Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer." Radiation oncology.. 2011 Jun 30; 6:80. Epub 2011 Jun 30.
4/2011
Peslak SA, Wenger J, Bemis JC, Kingsley PD, Frame JM, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J. "Sublethal radiation injury uncovers a functional transition during erythroid maturation." Experimental hematology.. 2011 Apr; 39(4):434-45. Epub 2011 Feb 01.
1/10/2011
Sun H, Tsai Y, Nowak I, Dertinger SD, Wu JH, Chen Y. "Response kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture." Mutation research.. 2011 Jan 10; 718(1-2):38-43. Epub 2010 Nov 04.
7/1/2010
Tucker SL, Jin H, Wei X, Wang S, Martel MK, Komaki R, Liu HH, Mohan R, Chen Y, Cox JD, Liao Z. "Impact of toxicity grade and scoring system on the relationship between mean lung dose and risk of radiation pneumonitis in a large cohort of patients with non-small cell lung cancer." International journal of radiation oncology, biology, physics.. 2010 Jul 1; 77(3):691-8. Epub 2009 Oct 14.
2/2010
Metcalfe SK, Milano MT, Bylund K, Smudzin T, Rubin P, Chen Y. "Split-course palliative radiotherapy for advanced non-small cell lung cancer." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2010 Feb; 5(2):185-90.
2/2010
Chen Y, Tsai Y, Nowak I, Wang N, Hyrien O, Wilkins R, Ferrarotto C, Sun H, Dertinger SD. "Validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and CBMN assays in a mouse model." Health physics.. 2010 Feb; 98(2):218-27.
9/1/2009
Chawla S, Chen Y, Katz AW, Muhs AG, Philip A, Okunieff P, Milano MT. "Stereotactic body radiotherapy for treatment of adrenal metastases." International journal of radiation oncology, biology, physics.. 2009 Sep 1; 75(1):71-5. Epub 2009 Feb 26.
9/2009
Roscoe JA, Bushunow P, Jean-Pierre P, Heckler CE, Purnell JQ, Peppone LJ, Chen Y, Ling MN, Morrow GR. "Acupressure bands are effective in reducing radiation therapy-related nausea." Journal of pain and symptom management.. 2009 Sep; 38(3):381-9. Epub 2009 Mar 28.
8/1/2009
Woodward WA, Bristow RG, Clarke MF, Coppes RP, Cristofanilli M, Duda DG, Fike JR, Hambardzumyan D, Hill RP, Jordan CT, Milas L, Pajonk F, Curran WJ, Dicker AP, Chen Y. "Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials." International journal of radiation oncology, biology, physics.. 2009 Aug 1; 74(5):1580-91. Epub 2009 Jun 17.
8/1/2009
Albain KS, Swann RS, Rusch VW, Turrisi AT, Shepherd FA, Smith C, Chen Y, Livingston RB, Feins RH, Gandara DR, Fry WA, Darling G, Johnson DH, Green MR, Miller RC, Ley J, Sause WT, Cox JD. "Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial." Lancet.. 2009 Aug 1; 374(9687):379-86. Epub 2009 Jul 24.
6/2009
Jin H, Tucker SL, Liu HH, Wei X, Yom SS, Wang S, Komaki R, Chen Y, Martel MK, Mohan R, Cox JD, Liao Z. "Dose-volume thresholds and smoking status for the risk of treatment-related pneumonitis in inoperable non-small cell lung cancer treated with definitive radiotherapy." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.. 2009 Jun; 91(3):427-32. Epub 2008 Oct 18.
6/2009
Milano MT, Chen Y, Katz AW, Philip A, Schell MC, Okunieff P. "Central thoracic lesions treated with hypofractionated stereotactic body radiotherapy." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.. 2009 Jun; 91(3):301-6. Epub 2009 Mar 28.
4/30/2009
Dertinger SD, Bemis JC, Phonethepswath S, Tsai Y, Nowak I, Hyrien O, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: effect of age." Mutation research.. 2009 Apr 30; 675(1-2):77-80. Epub 2009 Feb 11.
2009
Sun H, Dertinger SD, Hyrien O, Wu JH, Chen Y. "Gamma-radiation induces micronucleated reticulocytes in 3D bone marrow bioreactors in vitro." Mutation research.. 2009 680(1-2):49-55. Epub 2009 Sep 26.
9/2008
Okunieff P, Chen Y, Maguire DJ, Huser AK. "Molecular markers of radiation-related normal tissue toxicity." Cancer metastasis reviews.. 2008 Sep; 27(3):363-74.
6/1/2008
Chen Y, Pandya KJ, Feins R, Johnstone DW, Watson T, Smudzin T, Keng PC. "Toxicity profile and pharmacokinetic study of a phase I low-dose schedule-dependent radiosensitizing paclitaxel chemoradiation regimen for inoperable non-small-cell lung cancer." International journal of radiation oncology, biology, physics.. 2008 Jun 1; 71(2):407-13. Epub 2007 Dec 31.
6/2008
Zhang H, Hyrien O, Pandya KJ, Keng PC, Chen Y. "Tumor response kinetics after schedule-dependent paclitaxel chemoradiation treatment for inoperable non-small cell lung cancer: a model for low-dose chemotherapy radiosensitization." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2008 Jun; 3(6):563-8.
12/1/2007
Dertinger SD, Tsai Y, Nowak I, Hyrien O, Sun H, Bemis JC, Torous DK, Keng P, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry." Mutation research.. 2007 Dec 1; 634(1-2):119-25. Epub 2007 Jul 05.
12/1/2007
Chambers MS, Jones CU, Biel MA, Weber RS, Hodge KM, Chen Y, Holland JM, Ship JA, Vitti R, Armstrong I, Garden AS, Haddad R. "Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia." International journal of radiation oncology, biology, physics.. 2007 Dec 1; 69(5):1369-76. Epub 2007 Sep 12.
1/10/2007
Dertinger SD, Miller RK, Brewer K, Smudzin T, Torous DK, Roberts DJ, Avlasevich SL, Bryce SM, Sugunan S, Chen Y. "Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage." Mutation research.. 2007 Jan 10; 626(1-2):111-9. Epub 2006 Oct 23.
4/1/2006
Chen Y, Trotti A, Coleman CN, Machtay M, Mirimanoff RO, Hay J, O'brien PC, El-Gueddari B, Salvajoli JV, Jeremic B. "Adverse event reporting and developments in radiation biology after normal tissue injury: International Atomic Energy Agency consultation." International journal of radiation oncology, biology, physics.. 2006 Apr 1; 64(5):1442-51. Epub 2006 Jan 18.
5/1/2005
Chen Y, Hyrien O, Williams J, Okunieff P, Smudzin T, Rubin P. "Interleukin (IL)-1A and IL-6: applications to the predictive diagnostic testing of radiation pneumonitis." International journal of radiation oncology, biology, physics.. 2005 May 1; 62(1):260-6.
5/1/2005
Okunieff P, Cornelison T, Mester M, Liu W, Ding I, Chen Y, Zhang H, Williams JP, Finkelstein J. "Mechanism and modification of gastrointestinal soft tissue response to radiation: role of growth factors." International journal of radiation oncology, biology, physics.. 2005 May 1; 62(1):273-8.
2005
Okunieff P, Fenton B, Chen Y. "Past, present, and future of oxygen in cancer research." Advances in experimental medicine and biology.. 2005 566:213-22.
2/2004
Chen Y, Okunieff P. "Radiation and third-generation chemotherapy." Hematology/oncology clinics of North America.. 2004 Feb; 18(1):55-80.
2004
Dertinger SD, Camphausen K, Macgregor JT, Bishop ME, Torous DK, Avlasevich S, Cairns S, Tometsko CR, Menard C, Muanza T, Chen Y, Miller RK, Cederbrant K, Sandelin K, Pontén I, Bolcsfoldi G. "Three-color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood." Environmental and molecular mutagenesis.. 2004 44(5):427-35.
12/9/2003
Dertinger SD, Chen Y, Miller RK, Brewer KJ, Smudzin T, Torous DK, Hall NE, Olvany KA, Murante FG, Tometsko CR. "Micronucleated CD71-positive reticulocytes: a blood-based endpoint of cytogenetic damage in humans." Mutation research.. 2003 Dec 9; 542(1-2):77-87.
8/2003
Liu W, Chen Y, Wang W, Keng P, Finkelstein J, Hu D, Liang L, Guo M, Fenton B, Okunieff P, Ding I. "Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth." American journal of clinical oncology.. 2003 Aug; 26(4):S103-9.
7/2003
Williams J, Chen Y, Rubin P, Finkelstein J, Okunieff P. "The biological basis of a comprehensive grading system for the adverse effects of cancer treatment." Seminars in radiation oncology.. 2003 Jul; 13(3):182-8.
3/2003
Chen Y, Pandya K, Keng PC, Johnstone D, Li J, Lee YJ, Smudzin T, Okunieff P. "Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2003 Mar; 9(3):969-75.
2003
Chen Y, Okunieff P, Ahrendt SA. "Translational research in lung cancer." Seminars in surgical oncology.. 2003 21(3):205-19.
1/2002
Chen Y, Williams J, Ding I, Hernady E, Liu W, Smudzin T, Finkelstein JN, Rubin P, Okunieff P. "Radiation pneumonitis and early circulatory cytokine markers." Seminars in radiation oncology.. 2002 Jan; 12(1 Suppl 1):26-33.
12/20/2001
Chen Y, Taghian AG, Rosenberg AE, O'Connell J, Okunieff P, Suit HD. "Predictive value of histologic tumor necrosis after radiation." International journal of cancer.. 2001 Dec 20; 96(6):334-40.
10/2001
Chen Y, Pandya K, Keng PP, Feins R, Raubertas R, Smudzin T, Rosenblatt J, Okunieff P. "Schedule-dependent pulsed paclitaxel radiosensitization for thoracic malignancy." American journal of clinical oncology.. 2001 Oct; 24(5):432-7.
3/1/2001
Chen Y, Rubin P, Williams J, Hernady E, Smudzin T, Okunieff P. "Circulating IL-6 as a predictor of radiation pneumonitis." International journal of radiation oncology, biology, physics.. 2001 Mar 1; 49(3):641-8.
6/1999
Okunieff P, Barrett AJ, Phang SE, Li A, Constine LS, Williams JP, Rubin P, Wang X, Wu T, Chen Y, Ding I. "Circulating basic fibroblast growth factor declines during Cy/TBI bone marrow transplantation." Bone marrow transplantation.. 1999 Jun; 23(11):1117-21.
1994
Poot M, Hoehn H, Kubbies M, Grossmann A, Chen Y, Rabinovitch PS. "Cell-cycle analysis using continuous bromodeoxyuridine labeling and Hoechst 33358-ethidium bromide bivariate flow cytometry." Methods in cell biology.. 1994 41:327-40.
1/1992
Chen Y, Richards TL, Izenberg S, Golden RN, Williams DL, Nelson JA, Steen RG. "In vivo phosphorus NMR spectroscopy of skin using a crossover surface coil." Magnetic resonance in medicine.. 1992 Jan; 23(1):46-54.
10/1990
Chen YY, Rabinovitch PS. "Mitogen response and cell cycle kinetics of Swiss 3T3 cells in defined medium: differences from human fibroblasts and effects of cell density." Experimental cell research.. 1990 Oct; 190(2):145-50.
7/1990
Chen YY, Rabinovitch PS. "Altered cell cycle responses to insulin-like growth factor I, but not platelet-derived growth factor and epidermal growth factor, in senescing human fibroblasts." Journal of cellular physiology.. 1990 Jul; 144(1):18-25.
1990
Poot M, Hoehn H, Kubbies M, Grossmann A, Chen YC, Rabinovitch PS. "Cell cycle analysis using continuous bromodeoxyuridine labeling and Hoechst 33258-ethidium bromide bivariate flow cytometry." Methods in cell biology.. 1990 33:185-98.
7/1989
Chen Y, Rabinovitch PS. "Platelet-derived growth factor, epidermal growth factor, and insulin-like growth factor I regulate specific cell-cycle parameters of human diploid fibroblasts in serum-free culture." Journal of cellular physiology.. 1989 Jul; 140(1):59-67.
9/1988
Raghu G, Chen YY, Rusch V, Rabinovitch PS. "Differential proliferation of fibroblasts cultured from normal and fibrotic human lungs." The American review of respiratory disease.. 1988 Sep; 138(3):703-8.
2/1988
Rabinovitch PS, Kubbies M, Chen YC, Schindler D, Hoehn H. "BrdU-Hoechst flow cytometry: a unique tool for quantitative cell cycle analysis." Experimental cell research.. 1988 Feb; 174(2):309-18.