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Kenneth Y. Usuki, M.D.

Contact Information

Phone Numbers

Appointment: (585) 275-2171

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Settings

Cancer, Radiation Oncology


Professional Background

Dr. Kenneth Usuki is a board certified Radiation Oncologist and Associate Professor of Radiation Oncology. He earned his Doctorate of Medicine degree from Jefferson Medical College in Philadelphia, PA. He then went on to complete a surgical/transitional internship at the University of Pennsylvania Hospital System in Philadelphia, PA, and then residency in Radiation Oncology at the University of Rochester’s Strong Memorial Hospital where he served as chief resident.

Dr. Usuki's primary research and clinical practice includes neuro-oncologic patients with primary malignant brain (glioma, ependymoma, meningioma, and schwannoma)/spine tumors, metastatic lesions to the brain/spine, and benign brain/spine lesions and applying cutting edge radiation treatments such as Stereotactic Radio Surgery (SRS), Brain Lab Cranial Elements SRS, Brain Lab Cranial Multiple Metastases, Intensity Modulated Radiation Therapy (IMRT), VMAT- volumetric-modulated arc therapy, and Image Guided Radiation Therapy (IGRT) with Robotics to the brain and spine. Dr. Usuki serves as the Co-Director of the University of Rochester Spinal Radiosurgery program.

Dr. Usuki also specializes in skin cancers including melanoma, Merkel cell, squamous cell, and basal cell, and utilizes Tomotherapy, VMAT therapy, and electron therapy for the treatment of these diseases. He also treats patients with gastrointestinal tumors including esophagus, rectum, stomach, liver, and pancreas.

Dr. Usuki is heavily involved in the education of residents and medical students at the University of Rochester's School of Medicine and Dentistry. He serves as the Associate Radiation Oncology Residency Director, the Radiation Oncology Medical Student Clerkship Director, and as the Wellness Representative of the Department of Radiation Oncology.



  • Radiation Oncology - American Board of Radiology


MD | Jefferson Medical College of Thomas Jefferson Univ

Post-doctoral Training & Residency

07/01/2005 - 06/30/2009
Residency in Radiation Oncology at University of Rochester Medical Center

06/25/2004 - 06/24/2005
Internship in Transitional at Presbyterian Medical Center (UPHS)

Clinical Trials

Phase III Trial of Post-Surgical Single Fraction Stereotactic Radiosurgery (SRS) Compared With Fractionated SRS for Resected Metastatic Brain Disease

Lead Researcher: Kenneth Y Usuki

This phase III trial studies how well single fraction stereotactic radiosurgery works compared with fractionated stereotactic radiosurgery in treating patients with cancer that has spread to the brain from other parts of the body and has been removed by surgery. Single fraction stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue. Fractionated stereotactic radiosurgery delivers multiple, smaller doses of radiation therapy over time. This study may help doctors find out if fractionated stereotactic radiosurgery is better or worse than the usual approach with single fraction stereotactic radiosurgery.

View Study Details


Journal Articles

Brown PD, Gondi V, Pugh S, Tome WA, Wefel JS, Armstrong TS, Bovi JA, Robinson C, Konski A, Khuntia D, Grosshans D, Benzinger TLS, Bruner D, Gilbert MR, Roberge D, Kundapur V, Devisetty K, Shah S, Usuki K, Anderson BM, Stea B, Yoon H, Li J, Laack NN, Kruser TJ, Chmura SJ, Shi W, Deshmukh S, Mehta MP, Kachnic LA, . "Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2020 Apr 1; 38(10):1019-1029. Epub 2020 Feb 14.

Milano MT, Bates JE, Budnik J, Qiu H, Hardy S, Cummings MA, Baumgart MA, Maggiore RJ, Mulford DA, Usuki KY. "Risk of brain metastases in T1-3N0 NSCLC: a population-based analysis." . 2020 Feb 25; 9(1):LMT25. Epub 2020 Feb 25.

Cummings MA, Usuki KY, Fleming FJ, Tejani MA, Katz AW. "Short course radiation therapy for rectal cancer in the elderly: can radical surgery be avoided?" Journal of gastrointestinal oncology.. 2019 Apr 0; 10(2):357-361.

Books & Chapters

Chapter Title: Metastatic Disease: Bone, Spinal Cord, Brain, Liver and Lung
Book Title: Clinical Radiation Oncology, 4th Edition
Author List: Usuki KY; Milano MT; David M; Okunieff P
Edited By: Gunderson LL; Tepper JE
Published By: Churchill Livingstone 2016 in Philadelphia

Chapter Title: Radiation Necrosis
Book Title: Image-Guided Hypofractionated Stereotactic Radiotherapy (IG-hSRT) A Practical Approach to SRT for Brain and Spine Tumor, 1st Edition
Author List: Usuki KY; Milano MT
Edited By: Sahgal A; Lo SS; Ma L; Sheehan JP
Published By: CRC Press 2016 in New York