Clive S. Zent, M.D.

Clive S. Zent, M.D.

Contact Information

James P. Wilmot Cancer Center
601 Elmwood Ave.
Rochester, NY 14642

Appointment: (585) 275-5823

  • Accepting New Patients Accepting New Patients
  • Admits to Strong Memorial Hospital Admits to Strong Memorial Hospital
  • Admits to Highland Hospital Admits to Highland Hospital

Professional Bio

Dr. Clive Zent is a highly experienced hematologist and internationally recognized researcher and expert in the care of patients with chronic lymphocytic leukemia (CLL) and related lymphoid malignancies. While training in Hematology at the University of Chicago, Dr. Zent studied the molecular genetics of hematological malignancies in the laboratory of Dr. Janet Rowley. His clinical and research interest in CLL started as an attending physician at the Central Arkansas Veterans Healthcare System and continued when he joined the staff of the Mayo Clinic in Rochester MN in 2003. In 2013 he was appointed to the faculty of the Wilmot Cancer Center at the University of Rochester Medical Center as Professor of Medicine and director of the Chronic Lymphocytic Leukemia program.

Dr. Zent's research has improved our understanding of the therapeutic monoclonal antibodies used to treat CLL, use of molecular prognostic markers in the management of CLL, diagnosis of CLL and related diseases, and evaluation and management of autoimmune cytopenias and second malignancies complicating CLL. His goal as a clinician, researcher and teacher is to continue to improve treatment and outcome for patients with CLL.

Patient Care Bio

I chose this specialty because I have always had an interest in diseases of the blood. My patients can be confident knowing I provide optimal individual patient care based on precision diagnosis and targeted therapy. Although I treat many types of blood diseases, my area of expertise is chronic lymphocytic leukemia.

Conditions I Treat:

- Chronic lymphocytic leukemia/Small lymphocytic lymphoma (CLL)
- Hairy cell leukemia
- Prolymphocytic leukemia
- Lymphoplasmacytic lymphoma (Waldenstrom's macroglobulinemia)
- Large granular lymphocytic leukemia

Awards & Honors (Local)

Teacher of the Year in Hematology | Mayo Fellows Association, College of Medicine | Mayo Clinic 2008
Kaminer Fellowship (Travel Award) | University of Chicago | Chicago, IL 1995
Degree with Distinction | University of the Witwatersrand | South Africa 1983

Current Appointments

Professor - Department of Medicine, Hematology/Oncology (SMD) - Primary
Professor - Cancer Center


Hematology - American Board of Internal Medicine
Internal Medicine - American Board of Internal Medicine


MBBCh | University of the Witwatersrand1983
MMed | Internal Medicine | University of Cape TownAttended 1987 - 1991

Post-Doctoral Training & Residency

Residency in Internal Medicine at University of Arkansas College of Medicine07/01/1996 - 6/30/1997
Fellowship in Hematology at University of Chicago Medical Center07/01/1993 - 6/30/1996
Residency in Internal Medicine at Groote Schuur Hospital - University of Cape Town02/01/1987 - 1/31/1991
Internship in Internal Medicine at University of Witwatersrand01/01/1984 - 12/31/1984