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Clinical Trials

Clinical trials are research studies that help doctors find new and better ways to prevent and treat diseases. Carefully conducted clinical trials are the most effective and safest way to find treatments that work. Search below to find clinical trials for urologic conditions currently being conducted at the University of Rochester Medical Center. Talk with your doctor to decide if a clinical trial is right for you. 

For more information about the research or participation, please call our clinical trial help line at (585) 275-0126.

Current Urology Trials:

Prostate Studies

A Prospective Pre-Market Study for Ex Vivo Raman Spectra Collection with the Sentry Prostate System after Robotic- Assisted Prostatectomy

Available to men diagnosed with prostate cancer scheduled for removal of the prostate gland through surgery, who are willing to consent to tissue examination after standard prostate surgery.

This purpose of this study is to compare pictures taken of the prostate with an investigational device, to those pictures produced with routine pathological processing.  

4-aminopyridine Treatment for Nerve Injury Resulting from Radical Retro-Pubic Prostatectomy

Available to men, at minimum, diagnosed with early stage prostate cancer, between the ages of 45-75, scheduled for removal of the prostate gland through surgery.

Surgery is a very effective modality for prostate cancer treatment but with detrimental effect on erectile function and urinary control.  The purpose of this study is to evaluate the effects of a study drug on recovery from nerve damage that may have resulted from your surgery.  Nerve damage that can be associated with erectile dysfunction and incontinence. ​

Bladder studies

A Randomized Phase III Double-blind Clinical Trial Evaluating the Effect of Immune-enhancing Nutrition on Radical Cystectomy Outcomes

Available to men and women, diagnosed with bladder cancer, and undergoing bladder removal surgery, 18 years of age or older.

The purpose of this study is to determine whether taking a nutritional drink before and after your bladder removal surgery will help in preventing infection and other problems that can occur with the removal of the bladder.

Kidney Studies

Phase III Trial of Immunotherapy-Based Combination Therapy with or Without Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma

Available to men and women with newly diagnosed metastatic kidney cancer, 18 years of age or older.  

The purpose of this study is to determine whether a nephrectomy (removal of kidney) plus standard of care treatment is better than standard of care treatment alone. 

Establishing the Safety and Efficacy of Reloxaliase (Oxalate Decarboxylase) in Patients with Enteric Hyperoxaluria: A Phase III Randomized, Double-Blind, Placebo-Controlled Study

Available to men and women, with documented kidney stone(s), that have large amounts of oxalate in their urine (hyperoxaluria), along with an absorption disorder of their intestines, 18 years of age or older. 

The purpose of this study is to evaluate how well the study drug works for the treatment of your hyperoxaluria and the decrease of kidney stones.