
Welcome to the Gail Johnson Lab
The primary focus of Dr. Gail Johnson’s research group is on the molecular mechanisms of neurodegeneration. The lab has a longstanding interest in the pathogenic processes in Alzheimer disease, and more recently in stroke and spinal cord injury (SCI). For their studies they use a wide variety of different approaches from in vitro enzyme assays with purified proteins, to studies in whole animals. This broad-based approach allows them to translate what they learn about a process or signaling pathway at the molecular level to the in vivo situation. Each of these 2 areas of research that are ongoing in the lab are discussed briefly below.

Gail V. Johnson, Ph.D.
Principal Investigator
Publications
View All Publications- Tau clearance reverses touch neuron dysfunction in both young and aged C. elegans.; Journal of Alzheimer's disease : JAD. 2025 Nov 24.
- A Bioinformatic Analysis of BAG Protein Interactors and Pathways in Alzheimer's and Parkinson's Disease.; bioRxiv : the preprint server for biology. 2025 Jul 23.
- Tau Clearance Reverses Neuronal Dysfunction in Both Young and Aged C. elegans.; bioRxiv : the preprint server for biology. 2025 Jun 25.
- Cyclophilin D (CypD) ablation prevents neurodegenerative and cognitive damage induced by caspase-3 cleaved tau.; Free radical biology & medicine. 2025 Feb 27.
- One BAG doesn't fit all: the differences and similarities of BAG family members in mediating CNS homeostasis.; Biological psychiatry. 2025 Jan 08.
Contact Us
Gail Johnson Lab
601 Elmwood Ave, Box 604
Rochester, NY 14642