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Research

Cell Cycle & Cancer

Cell Cycle & CancerUnderstanding the differences in cell division and its relationship to the development of cancer.

Active Research Laboratories

  • Land Lab - Cooperation of Oncogenic Mutations in the Control of Malignancy
  • Maines Lab - Heme Oxygenase, Biliverdin Reductase & Cell Signaling
  • Munger Lab - Mechanisms of Pathogenic Metabolic Manipulation

Cell Signaling & Metabolic Regulation

Cell Signaling & Metabolic RegulationUnderstanding complex system of communication that governs basic cellular activities and coordinates cell actions in order to effectively treat diseases.

Active Research Laboratories

  • Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
  • Land Lab - Cooperation of Oncogenic Mutations in the Control of Malignancy
  • Munger Lab - Mechanisms of Pathogenic Metabolic Manipulation

Chromatin Structure, Gene Regulation & Repair

Chromatin Structure, Gene Regulation & RepairStudy of defined protein-DNA interactions, protein modification and mutations that influence chromatin structure and gene regulation.

Active Research Laboratories

Genomics & Model Systems for Development

Genomics & Model Systems for DevelopmentDetermining DNA sequences of organisms and fine-scale genetic mapping efforts.

Active Research Laboratories

  • Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
  • Grayhack Lab - The Roles of the Genetic Code in Translation
  • Phizicky Lab - tRNA Biogenesis, Function & Quality Control
  • Puzas Lab - Molecular and Cellular Biology of the Skeletal System

Membrane Biology

Membrane BiologyThe study of the biological and physiochemical characteristics of membranes.

Active Research Laboratories

  • Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
  • Grossfield Lab - Computer Modeling to Understand Structure and Thermodynamics of Biological Molecules
  • Mathews Lab - Computational Biology and Bioinformatics
  • Waugh Lab - Cell Deformability & Cell Adhesion

Molecular Biophysics

Molecular BiophysicsCombines concepts in physics, chemistry, engineering, mathematics and biology.

Active Research Laboratories

  • Ermolenko Lab - Structural Dynamics of Translation
  • Grossfield Lab - Computer Modeling to Understand Structure and Thermodynamics of Biological Molecules
  • Kielkopf Lab - Pre-mRNA Splicing for Treatment of Human Disease
  • Benjamin Miller Lab - Molecular Recognition & Biosensing
  • Wedekind Lab - Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics

Protein Structure & Function

Protein Structure & FunctionStructure and function of proteins from primary to quaternary structures.

Active Research Laboratories

  • Dumont Lab - Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
  • Ermolenko Lab - Structural Dynamics of Translation
  • Hayes Lab - Chromatin Structure
  • Kielkopf Lab - Pre-mRNA Splicing for Treatment of Human Disease
  • Maines Lab - Heme Oxygenase, Biliverdin Reductase & Cell Signaling
  • Maquat Lab - Normal & Disease-Associated RNA Decay
  • Benjamin Miller Lab - Molecular Recognition & Biosensing
  • Phizicky Lab - tRNA Biogenesis, Function & Quality Control
  • Smith Lab - Messenger RNA Expression & Processing
  • Wedekind Lab - Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
  • Yu Lab - Functions & Mechanisms of RNA Modifications

RNA Structure & Processing

RNA Structure & ProcessingGeneration of a mature mRNA (for protein genes) or a functional tRNA or rRNA from the primary transcript.

Active Research Laboratories

  • Butler Lab - Regulation of Gene Expression by Targeted Degradation of RNA
  • Ermolenko Lab - Structural Dynamics of Translation
  • Kielkopf Lab - Pre-mRNA Splicing for Treatment of Human Disease
  • Li Lab - Reproductive and RNA Biology
  • Maquat Lab - Normal & Disease-Associated RNA Decay
  • Mathews Lab - Computational Biology and Bioinformatics
  • Phizicky Lab - tRNA Biogenesis, Function & Quality Control
  • Smith Lab - Messenger RNA Expression & Processing
  • Wedekind Lab - Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
  • Yu Lab - Functions & Mechanisms of RNA Modifications