Stages of Rhabdomyosarcoma There are several staging systems for childhood rhabdomyosarcoma. The treatment options in this summary are based on size, location, and how far and where the cancer has spread. Stage I Cancer is found in the eye, head and/or neck, or near the sex organs and bladder Stage II Cancer is located in only 1 area (but in none of the areas in Stage I), is smaller than 2 inches (5 cm) in size, and has not spread to the lymph nodes. Stage III Cancer is located in only 1 area (but in none of the areas in Stage I), is greater than 2 inches (5 cm) in size, and may have spread to the lymph nodes found near the cancer. Stage IV Cancer has spread and is found in more than 1 place at the time of diagnosis. Recurrent The cancer has come back after it has been treated. It may come back in the area where it first started or in another part of the body.