Our work in Global Health focuses on identifying environmental, nutritional, and behavioral risk factors to reduce morbidity and improve health around the world. To examine the potential health effects of prevalent environmental contaminants, we have established long-term studies in Beijing, the Seychelles, and the Slovak Republic in collaboration with local health partners. Work to improve linkage to and retention in the continuum of HIV care has resulted in collaborations with investigators from the Chinese Centers for Diseases Control and Prevention, and Vanderbilt and Yale Universities to develop innovative behavioral interventions among Chinese men who have sex with men in Beijing. Also, PHS faculty and partners in South Africa, Ghana, Niger, and Senegal are working to engage grass-roots organizations to reduce HIV stigma and discrimination. Finally, a partnership is being developed with a community health center in Buenos Aires to identify community and health providers’ priorities for research and interventions.