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2017

Clarence Ling, Ph.D.

Regulation of Ribosome Structural Dynamics by Antibiotics, Translation Factors and mRNA Secondary Structure

Advisor: Dmitri N. Ermolenko, Ph.D.

Now: Clinical Chemistry Postdoctoral Fellow at NIH

Michael Sloma

Computational Tools for RNA Structure Prediction

Advisor: David H. Mathews, M.D., Ph.D.

2016

Shihao Xu, Ph.D.

The Impact of Oncogenic Signaling on Metabolic Stress Responses and Human Cytomegalovirus Infection

Advisor: Joshua C. Munger, Ph.D.

Now: Postdoctoral Associate at Department of Immunology, Yale School of Medicine

2015

Angela Balliano, Ph.D.

Characterization of ATP-Dependent Chromatin Remodeler-Nucleosome Interactions and Analysis of the Role of HMGB1 in Base Excision Repair

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Post Doctoral Fellow, Hayes' Lab at University of Rochester, Department of Biochemistry & Biophysics

Stefanie DeVito, Ph.D.

Contributions of Pyrimidine Biosynthesis to Viral Infection

Advisor: Joshua C. Munger, Ph.D.

Now: Assistant Professor at Department of Biological Sciences, University of Delaware

Marina Feigenson, Ph.D.

Investigating the Role of Prostaglandin E2 Receptor Subtype 1 in Mesenchymal Stem Cell Differentiation

Advisor: Regis O'Keefe, M.D., Ph.D.

Now: Postdoctoral Fellow at Harvard School of Dental Medicine

Guangze Jin, Ph.D.

Characterization of PIN-domain Toxin-antitoxins VapBC from Mycobacterium tuberculosis

Advisor: Scott Butler, Ph.D.

Now: Postdoctoral Associate at University of Rochester

Morgan Monaghan, Ph.D.

Identification of A2 Inter-Subunit Interactions in Factor VIIIa of the Blood Clotting Pathway

Advisor: Philip J. Fay, Ph.D.

Now: Postdoctoral Fellow at Department of Biochemistry & Biophysics, University of Rochester

Kevin Murphy, Ph.D.

The Non-Histone Protein HMGN1 Alters Core Histone Tail and H1 Interactions to Modify Higher-Order Chromatin Structure

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Senior Scientist at Veterinary Medicine R&D, Zoetis Inc.

Chinmay Surve, Ph.D.

Stimulation of Neutrophil Migration through the Dynamic Regulation of Signaling by the Heterotrimeric G Proteins ai and bgSubunit

Advisor: Alan Victor Smrcka, Ph.D.

Now: Research Fellow at Integrated Imaging Program, Albert Einstein College of Medicine

Yongchun Zhang, Ph.D.

Beta-catenin signaling integrates with BMP2 and CCN1 signaling to regulate chondrocyte differentiation and cartilage development

Advisor: Regis O'Keefe, M.D., Ph.D.

Now: Postdoctoral Fellow at Columbia University Medical Center (Jianwen Que Lab)

2014

Brenda Cadiz-Rivera, Ph.D.

Hyperacetylated Domain Formation and cis-acting Regulatory DNA Sequences within the Murine β-globin Locus

Advisor: Michael D. Bulger, Ph.D.

Now: Research Associate at University of Puerto Rico

Joshua Dewe, Ph.D.

Characterizing the Role of Elongation Factor 1A and Other Cellular Proteins in the Yeast Rapid tRNA Decay Pathway

Advisor: Eric Phizicky, Ph.D.

Now: Principal Scientist I at Cell Line Development, Eurofins Lancaster Laboratories

Joseph Liberman, Ph.D.

Structural and Functional Analysis of Gene Regulatory PreQ1 Riboswitches

Advisor: Joseph E. Wedekind, Ph.D.

Now: Postdoctoral Fellow at Department of Molecular, Cellular, and Developmental Biology, Yale University

William McDougall, Ph.D.

Characterization of the APOBEC3G ssDNA Editing Complex and its Regulation by RNA

Advisor: Harold C. Smith, Ph.D.

Now: Postdoctoral Fellow at Department of Microbiology and Physiological System, University of Massachusetts

David Rabayev, Ph.D.

Tissue Specific Gene Activation by a Class of Enhancers in Hyperacetylated Domains of Chromatin

Advisor: Michael D. Bulger, Ph.D.

Now: Editor's Assistant at JBC

Jiashi Wang, Ph.D.

Investigation of an evolutionarily conserved Staufen-mediated mRNA decay pathway that involves SINEs and lncRNAs

Advisor: Lynne Maquat, Ph.D.

2013

Kimberly Dean, Ph.D.

Selection, Identification, and Characterization of Codon Pairs that Inhibit Translation and the Development of the RNA-ID Method to Measure the Effects of Cis-Regulatory Elements

Advisor: Elizabeth Grayhack, Ph.D.

Now: Clinical Study Manager at Becton Dickinson

Geoffrey Lippa, Ph.D.

Thermodynamic Analysis and Characterization of Viral-Host Protein Interactions as a Preface to HIV Therapeutic Design

Advisor: Joseph E. Wedekind, Ph.D.

Now: Assistant Professor at Department of Biology, Alfred State University

Sharon Pepenella, Ph.D.

Characterization of Intra- and Inter-nucleosomal Interactions of the Histone H4 Tail Domain and the Effects of H4 Acetylation on Chromatin Structure

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Educator at Cold Spring Harbor Laboratory, DNA Learning Center

Cody Spencer, Ph.D.

Fatty Acid Biosynthesis: Elucidating the Mechanisms Behind the Manipulation and Necessity of a Metabolic Pathway Critical for Viral and Cancer Pathogenesis

Advisor: Joshua C. Munger, Ph.D.

Now: Senior Research Scientist at Bio X Cell

Jeffrey Zuber, Ph.D.

Identification of Mutations Affecting the Thermal Stability of Ste2p, a G Protein Coupled Receptor in S. cerevisiae

Advisor: Mark E. Dumont, Ph.D.

Now: Postdoctoral Fellow at Department of Biochemistry & Biophysics, University of Rochester

2012

Jennifer DeAngelis, Ph.D.

The Mechanisms for Catalytic Inactivation of FVIIIa by APC and Factor Xa

Advisor: Philip J. Fay, Ph.D.

Now: Photographer at Jennydee Photography

Rozzy Finn, Ph.D.

The Role of Glutamate Receptors in the Pathophysiology and Treatment of Infantile Neuronal Ceroid Lipofuscinosis

Advisor: David A. Pearce, Ph.D.

Now: Research Development and Technology Transfer Liaison at The University of South Dakota, Sioux Falls, South Dakota

Jason Gloor, Ph.D.

Binding and Cleavage Specificities of Human Dna2 and FEN1 Define Their Enzymatic Activities during DNA Replication and Repair

Advisor: Robert A. Bambara, Ph.D.

Now: Project Manager - Software Development at Excellus BCBS

Chenguang Gong, Ph.D.

Staufen1-Mediated mRNA Decay in Mammalian Cells

Advisor: Lynne Maquat, Ph.D.

Now: Presidential Postdoctoral Associate at Novartis Institute for Biomedical Research

Athena Kantartzis, Ph.D.

Understanding the Molecular Mechanisms of Genome Maintenance

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Medical Director of Chemistry/ Director of Toxicology at Brigham and Women's Hospital

Jessica McArdle, Ph.D.

Uncovering the Mechanism by Which Human Cytomegalovirus Mediates Glycolytic Activation

Advisor: Joshua C. Munger, Ph.D.

Now: Senior Molecular Biologist at ZeptoMetrix Corporation

Adam Miller, Ph.D.

Human Telomere DNA Damage by Oxidation and Direct Effect Ionizing Radiation, and the Promotion of Telomere DNA Repair by Telomere Proteins

Advisor: Robert A. Bambara, Ph.D.

Now: QC Scientist at Regeneron Pharmaceuticals

Karyn Schmidt, Ph.D.

Air Proteins Control Differential TRAMP Substrate Specificity for Nuclear RNA Surveillance

Advisor: Scott Butler, Ph.D.

Now: Postdoctoral Fellow at Department of Cancer Immunology & Aids, Harvard/Dana-Farber

Wen Shen, Ph.D.

Factors that Promote Strand Transfer Recombination during HIV-1 Reverse Transcription

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Director, Core Antisense Research at Ionis Pharmaceuticals

Guowei Wu, Ph.D.

Constitutive and inducible pseudouridylation of S. cerevisiae U2 snRNA

Advisor: Yi-Tao Yu, Ph.D.

Now: Postdoctoral Fellow at Department of Cellular and Molecular Medicine, University of California-San Diego

2011

Keith Connolly, Ph.D.

Quality control and organization of small ribosomal subunit biogenesis

Advisor: Gloria Culver, Ph.D.

Now: Scientist at EdiGene

Jennifer Gewandter, Ph.D.

Studies in Oxidative Damage Induced Signaling: A Focus Outside the Nucleus

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Professor at Department of Anesthesiology, University of Rochester

Ryan Henry, Ph.D.

Multiple Roles for Members of the Long Flap Pathway in Okazaki Fragment Processing

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Professor at Department of Chemistry, Wilkes University, PA

Christopher Hine, Ph.D.

Defying and Defeating Cancer: Hyaluronic Acid and the Rad51 Promoter

Advisor: Michael D. Bulger, Ph.D.

Now: Postdoctoral Research Fellow at Department of Genetics and Complex Diseases, Harvard School of Public Health

John Karijolich, Ph.D.

Regulation of Translation Termination by Box H/ACA RNP-mediated Post-transcriptional Modification

Advisor: Yi-Tao Yu, Ph.D.

Now: Assistant Professor at Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center

Holly Kuzmiak, Ph.D.

Roles of Hho1p, Esc2p, and the post-translational modification of Sir2p in transcriptional silencing in Saccharomyces cerevisiae

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Owner & Head Coach at Run with Holly

Ning Liu, Ph.D.

Mechanism of ySWI/SNF and RSC catalyzed nucleosome sliding

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Postdoctoral Research Fellow at Cornell University

David Stephenson, Ph.D.

Pseudouridylation of the Branch Site Recognition Region of U2 Affects Spliceosome Structure and Function

Advisor: Yi-Tao Yu, Ph.D.

Now: Patent Attorney at Kloss, Stenger & LoTempio

Amir Taslimi, Ph.D.

Conformational Changes Associated with Activation of the Yeast Saccharomyces cerevisiae α-factor Receptor Ste2p

Advisor: Mark E. Dumont, Ph.D.

Now: Postdoctoral Fellow at UC Denver

Joseph Whipple, Ph.D.

Defining the Substrate Specificity Determinants for the Yeast Rapid tRNA Decay Pathway and the Identification of Factors that Mediate Degradation

Advisor: Eric Phizicky, Ph.D.

Now: Development Scientist I at New England Biolabs

2010

Tamara Caterino, Ph.D.

Molecular Determinants of Linker Histone Binding to Nucleosomes

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Senior Clinical Research Scientist at Proctor and Gamble

Michael DeRan, Ph.D.

The Role of NPAT in S-Phase-Dependent Histone Gene Transcription and DNA Double-Strand Break Repair

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Research Scientist at Broad Institute, Wagner Group

Suresh DeSilva, Ph.D.

Development of a Bipartite Herpes Simplex Virus Sleeping Beauty Amplicon Vector Platform: Toward Site-Directed Integration of Large Transgenons Within the Human Genome

Advisor: William J. Bowers, Ph.D.

Now: Executive Director of Research at Shattuck Labs Inc.

Kriti Gaur, Ph.D.

A novel role for tumor suppressor gene Birt-Hogg-Dubé (BHD) in regulating ribosomal RNA (rRNA) synthesis

Advisor: Willis X. Li, Ph.D.

Amanda Getty, Ph.D.

Studies of the Cell Biology of CLN3 and Cell Motility Defects in the Cln3-/- Mouse

Advisor: David A. Pearce, Ph.D.

Now: Biology & Chemistry Instructor at Taft Educational Center

Chao Huang, Ph.D.

2'O-methylation of Yeast Telomerase in RNA

Advisor: Yi-Tao Yu, Ph.D.

Now: Senior Scientist I at Bristol-Myers Squibb

David Johnson, Ph.D.

Mitochondrial membrane fusion, pH homeostasis and ROS signaling in C. elegans

Advisor: Keith Webster Nehrke, Ph.D.

Now: Instructor at Department of Biology, Genesee Community College

Chun Mathers, Ph.D.

Mechanisms and Functional Roles of Pseudouridines in RNAs

Advisor: Yi-Tao Yu, Ph.D.

Now: Research Associate at Baylor Scott & White Health Careers

Jason Pike, Ph.D.

Understanding Why Three Pathways are Needed for Synthesis of Eukaryotic Nuclear DNA

Advisor: Robert A. Bambara, Ph.D.

Now: Value Based Payment Analyst at Excellus BCBS

Jason Salter, Ph.D.

Biophysical Characterization of the HIV-1 Viral Infectivity Factor and the Innate-Immunity Factor APOBEC3G

Advisor: Joseph E. Wedekind, Ph.D.

Now: Scientist at OyaGen Inc

2009

George Fromm, Ph.D.

The Formation and Function of Chromatin Domains at the Murine Beta Globin Locus

Advisor: Michael D. Bulger, Ph.D.

Now: Vice President of Research and Development at Shattuck Labs, Inc

Chad Galloway, Ph.D.

Metabolic Regulation and Structural Evaluation of APOBEC-1 Complementation Factor

Advisor: Harold C. Smith, Ph.D.

Now: Staff Scientist at Flaum Eye Institute, University of Rochester

David Hoffman, Ph.D.

The Production of Mitochondrial Reactive Oxygen Species at Steady-state Oxygen Concentrations: Implications for Oxygen Sensing

Advisor: Paul S. Brookes, Ph.D.

Now: Scientist I - Molecular Screening at Cayman Chemical

Jennifer Newell, Ph.D.

Contributions of Active Site Docking and Exosite Binding to the Mechanism of Thrombin-Catalyzed Activation of Factor VIII

Advisor: Philip J. Fay, Ph.D.

Now: Instructor and Lab Coordinator at University of Maine

Juanita Perera, Ph.D.

SYT-SSX1 Regulates PIASy Activity to Cause the Overexpression of NCOA3 in Synovial Sarcoma

Advisor: Yin Sun, Ph.D.

Now: Postdoctoral Research Scientist at German Cancer Research Center

Melanie Preston, Ph.D.

Investigation of the Roles of the Highly Conserved G-1 Residue of tRNAHis and Analysis of Unexpected Modification Changes in tRNAHis Variants in Saccharomyces cerevisiae

Advisor: Eric Phizicky, Ph.D.

Now: Scientific Instructional Designer I at Promega

Sean Rigby, Ph.D.

Mechanism Analysis of the Factors that Determine the Efficiency of Recombination Events during HIV-1 Reverse Transcription

Advisor: Robert A. Bambara, Ph.D.

Now: Technical Marketing Manager at Gas Treating Excellence- BASF Intermediates

Sabrina Seehafer, Ph.D.

Studies on the Biochemical and Immunological Consequence of Lysosomal Dysfunction in Neuronal Ceroid Lipofuscinoses

Advisor: David A. Pearce, Ph.D.

Now: DNA Criminalist at Dept. of Criminal Investigation, State of Iowa

Madhavika Serasinghe, Ph.D.

Identification of Novel Molecular Interactions of the Mitochondrial Fission Protein hFis1: Insight into its Action Mechanism and Therapeutic Potential

Advisor: Yisang Yoon, Ph.D.

Now: Instructor at Icahn School of Medicine at Mount Sinai

Jason Stewart, Ph.D.

Functional Interactions between Replication Protein A, Dna2, and Flap Endonuclease 1 during Okazaki Fragment Processing

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Professor, Department of Biology at University of South Carolina

Beth Van Winkle, Ph.D.

Monocytes and Their Mitochondria in Alzheimer's Disease

Advisor: Thomas E. Gunter, Ph.D.

Now: Postdoctoral Fellow at <a class="link-external" href="http://www.cornell.edu/">Cornell University</a>

Devin Wolfe, Ph.D.

The Interrelationship between pH, Btn1p and Phospholipid Regulation

Advisor: David A. Pearce, Ph.D.

Now: Senior Scientist at Genzyme

2008

Lindsay Burwell, Ph.D.

Identification of Mitochondrial S-nitrosothiols and Determination of the Protective Effect of Mitochondrial S-nitrosation in Cardiac Ischemia Reperfusion Injury

Advisor: Paul S. Brookes, Ph.D.

Now: Assistant Professor, Department of Chemistry at Wells College

Kevin Callahan, Ph.D.

Core exosome independent function of the nuclear exoribonuclease Rrp6p

Advisor: Scott Butler, Ph.D.

Now: Postdoctoral Research Associate at University of Rochester

Irina Chernyakov, Ph.D.

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22, and the 5’-3’ exonucleases Rat1 and Xrn1

Advisor: Eric Phizicky, Ph.D.

Now: Post Doctoral Fellow, Bretscher Lab at Cornell University

Hope Cole, Ph.D.

Activities of Two Base Excision Repair Enzymes on Nucleosomal Substrates

Advisor: Jeffrey J. Hayes, Ph.D.

Now: IRTA Fellow, Clark Lab at NIH

Lu Gao, Ph.D.

Factors That Promote Recombination during HIV-1 Reverse Transcription and Properties of M184 Drug Resistant Reverse Transcriptases

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Scientist Manager at Iowa State University

Min Song, Ph.D.

Unique Mechanisms that Control the Efficiency of HIV-1 Minus Strand Strong Stop Transfer

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant director of Core Antisense Research at Ionis Pharmaceuticals

Seasson Vitiello, Ph.D.

The Yeast Model for Batten Disease: Genetic and Physical Interactions

Advisor: David A. Pearce, Ph.D.

Now: Professor, Department of Genetics, Molecular Biology, Cell Biology and Cell Signaling at Augustana University

2007

Jared Benedict, Ph.D.

Elucidating and Characterizing the Interacting Partners of the Neuronal Ceroid Lipofuscinoses Proteins

Advisor: David A. Pearce, Ph.D.

Now: Sales &amp; Marketing Manager at <a class="link-external" href="http://www.kromasil.com/">Kromasil</a> at Eka Chemicals

Ryan Bennett, Ph.D.

A Functional Analysis of the Domains of APOBEC3G Involved in Dimerization, Anti-viral Activity and Cellular Localization

Advisor: Harold C. Smith, Ph.D.

Now: Scientist at Oyagen, Inc.

Patrick Brandt, Ph.D.

A Role for the Human Rad9-Rad1-Hus1 DNA Clamp Complex in DNA Repair

Advisor: Robert A. Bambara, Ph.D.

Now: Director of Career Development and Training at University of North Carolina at Chapel Hill

Jason Hoskins, Ph.D.

Analysis of the Mechanisms of 5-Fluorouracil Toxicity in Saccharomyces cerevisiae

Advisor: Scott Butler, Ph.D.

Now: Staff Scientist at National Cancer Institute

Lakmal Kotelawala, Ph.D.

Identification of Yeast tRNASer Um44 2'-O-Methyltransferase (Trm44) and Demonstration of a Role of Trm44 in Maintaining Levels of Specific tRNASer Species

Advisor: Eric Phizicky, Ph.D.

Now: Postdoctoral Researcher at University of Minnesota-Twin Cities

Celeste MacElrevey, Ph.D.

Crystallographic Analysis of a Small Catalytic RNA and Structural Insights into the Enzymes and Substrates of RNA / DNA Editing

Advisor: Joseph E. Wedekind, Ph.D.

Now: Senior Pharmacokineticist and QA Specialist at Nuventra Pharma Sciences

Marie Rossi, Ph.D.

Distinguishing the Pathways of Primer Removal during Eukaryotic Okazaki Fragment Maturation

Advisor: Robert A. Bambara, Ph.D.

Now: Manager, Technical Communications at Intrexon Corporation

Fatbardha Varfaj, Ph.D.

Contributions of Exosite Interactions and Active Site Docking to Activated Protein C-Catalyzed Inactivation of Factor VIIIa

Advisor: Philip J. Fay, Ph.D.

Now: Hematology Manager at Cerus

Xiaochao Wei, Ph.D.

Studies of Signaling Pathways in Cellular Responses to Titanium Particles: Implications of Cyclooxgenes-2/Prostaglandin E2/RANK Ligand Induction in Fibroblasts During Wear Debris-Induced Osteolysis

Advisor: Regis O'Keefe, M.D., Ph.D.

Now: Postdoctoral Fellow at <a class="link-external" href="http://wustl.edu/">Washington University at St. Louis</a>

Chunxing Yang, Ph.D.

Functions and Mechanisms of RNA Pseudouridylation

Advisor: Yi-Tao Yu, Ph.D.

Now: Researcher at Umass Medical School

Chujun Yuan, PhD

G Protein bg Subunit Mediated Signaling Specificity: Implications for bg subtypes and Novel Mechanisms of Activation

Advisor: Alan Victor Smrcka, Ph.D.

Now: Resident Physician at Nassau University Hospital

2006

Charles Ansong, Ph.D.

Probing Protein-Protein Interactions in Factor VIII: Characterization of Inter-Subunit Interactions and Epitope Mapping of Factor VIII Subunits

Advisor: Philip J. Fay, Ph.D.

Now: IO Engagement & Performance Scientist at Pacific Northwest National Laboratory

Varuni Jamburuthugoda, Ph.D.

dNTP Interaction Mechanisms of HIV-1 Reverse Transcriptase

Advisor: Baek Kim, Ph.D.

Now: Professor, Department of Biology at Fordham University

Xiaodong Li, Ph.D.

Functional Dissection of Estrogen Signaling Pathways Conveyed by Estrogen Receptor Homodimers and Heterodimer

Advisor: Russell Hilf, Ph.D.

Now: Director, Statistical Programming at Pharmapace Inc.

Craig Menges, Ph.D.

The Human Papillomavirus E7 Oncoprotein Upregulates AKT Activity through the Retinoblastoma Protein (Rb) during Keratinocyte Differentiation

Advisor: Mark E. Dumont, Ph.D.

Now: Research Associate at Fox Chase Cancer Center

Huan Kathy Wang, Ph.D.

Essential Role of Proteoglycans in Caenorhabditis elegans Early Embryonic Cell Division and Characterization of Sequence Requirement for Proteoglycan Modification Site

Advisor: Fred Hagen, Ph.D.

Now: Analyst, Risk Business Intelligence at Kaiser Permanente

2005

Anshika Bajaj, Ph.D.

Ligand Binding and Receptor Activation in a G Protein Coupled Receptor in Baker’s Yeast Saccharomyces cerevisiae

Advisor: Mark E. Dumont, Ph.D.

Now: Research Associate at <a class="link-external" href="http://www.amc.edu/">Albany Medical College</a>

Weifeng Gu, Ph.D.

Identification of the Essential Yeast Gene THG1 Encoding the Unusual tRNAHis Degree Guanylytransferase, and Elucidation of Multiple Consequences of Thg1p Post Depletion in vivo

Advisor: Eric Phizicky, Ph.D.

Now: Assistant Professor, Cell Biology and Neuroscience at University of California Riverside

Edward Petri, Ph.D.

Protein Engineering and Rational Mutagenesis in the Crystallization and Structure Determination of Human Cyclin B1

Advisor: Ravi Basavappa, Ph.D.

Now: Assistant Professor at University of Novi Sad

Huan Frank Wang, Ph.D.

Biochemistry and Physiology of Phospholipase C

Advisor: Alan Victor Smrcka, Ph.D.

Now: Postdoctoral Fellow at Wistar Institute</a>, Pennsylvania

Michael White, Ph.D.

Expression and Solubilization of Yeast Saccharomyces cerevisiae Integral Membrane Proteins for Functional and Structural Genomics

Advisor: Mark E. Dumont, Ph.D.

Now: Assistant Professor, Department of Genetics at Washington University in St. Louis

Kefang Xie, Ph.D.

Structural and Functional Analysis of APOBEC-Related Editing Enzymes, and the Structural Basis of Antibody Specificity in Blood Type Recognition

Advisor: Joseph E. Wedekind, Ph.D.

Now: Chemist at US Army Public Health Command

2004

Jing Huang, Ph.D.

Design of Estrogen Response Element (ERE) Binding Proteins to Study the Roles of ERE-containing Genes in Cell Proliferation and the Functional Differences Between ER Alpha and ER Beta

Advisor: Robert A. Bambara, Ph.D.

Now: Principal Investigator at The National Cancer Institute

Peter Klover

Obesity-Associated Interleukin-6 Contributes to Hepatic Insulin Resistance in Mice

Advisor: George Kimmich, Ph.D.

Now: Staff Scientist at Uniformed Services University of Health Sciences

Letian Kuai, Ph.D.

Degradation of mRNA in the nucleus and polyadenylation of noncoding RNA in Saccharomyces cerevisiae

Advisor: Fred Sherman, Ph.D.

Now: Investigator at GlaxoSmithKline

Xiaoju Ma, Ph.D.

Identification of Pseudouridylases Responsible for the Formation of Pseudouridines in Yeast U2 snRNA

Advisor: Yi-Tao Yu, Ph.D.

Now: Postdoctoral Fellow at Harvard Medical School

James Roussie

The Transport and Metabolism of the Neurotransmitter Glutamate: Regulation of the Glutamate Transport EAAC1 by Protein Kinase C; and Aminotransferase- Catalyzed Isotope Exchange and its Implications for the Glutamate-Glutamine Shuttle Model

Advisor: George Kimmich, Ph.D.

Now: Chief Scientific Officer at SiMPore

Hui-I Tom

The Mechanism of Minus Strand Stop Transfer during HIV-1 Reverse Transcription

Advisor: Robert A. Bambara, Ph.D.

Now: Senior Scientist, Molecular Analytical Development Imurities at Bristol-Myers Squibb

Mingxuan Xia

Cooperation of activated Ras and mutant p53 in control of cell motility and invasion during malignant cell transformation

Advisor: Hartmut Land, Ph.D.

Now: TBC at TBC

Chunyang Zheng, Ph.D.

Intra- and Inter-nucleosomal Protein-DNA Interactions of the Core Histone Tail Domains in a Model Dinucleosome and Oligonucleosome Array

Advisor: Jeffrey J. Hayes, Ph.D.

Now: President and CEO at Robustnique Corporation

2003

Sayura Aoyagi, Ph.D.

Investigation of the Mechanism of Nucleosome Remodeling by the Human SWI?SNF and Xenopus Mi-2 Chromatin Remodeling Complexes

Advisor: Jeffrey J. Hayes, Ph.D.

Now: Senior Medical Writer at Dynamed, EBSCO Information Services

Xi Chen

Investigation of Mitochondrial Protein Degradation Using Mutationally Altered Forms of Yeast Chromosome

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Professor (tenure Track) at University of Pittsburg

Yuan Liu

Study on Roles of Eukaryotic Flap Endonuclease 1 (FEN1) in Maintaining Stability of Repeat Sequences During RNA Replication

Advisor: Robert A. Bambara, Ph.D.

Now: Associate Professor, Department of Chemistry & Biochemistry at Florida International University

Mujib Rahman

Studying the Roles of Androgen Receptor (AR) Coactivators in Prostate Cancer Progression using Dominant-negative Mutants and RNA Interference

Advisor: Fred Sherman, Ph.D.

Now: Postdoctoral Fellow, Dept. of Medical Oncology at Dana Farber Cancer Institute

Ricardo Roda

The Mechanism of Recombination of HIV-1

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Professor of Neurology at John Hopkins Medicine

Stephen Tajc, Ph.D.

The molecular recognition of carbohydrates and ions in aqueous solution.

Advisor: Benjamin L. Miller, Ph.D.

Now: Assistant Professor of Chemistry at Nazareth College

Feng Xing, Ph.D.

A Family of Dihydrouridine Synthases with Different Specificities Responsible for Modification of Cytoplasmic tRNAs of Saccharomyces cerevisiae

Advisor: Eric Phizicky, Ph.D.

Now: Research Fellow at Memorial Sloan Kettering Cancer Center

2002

Tamara Ranalli

Analysis of Mammalian Base Excision Repair: Role of AP Endonuclease and Replication Protein A

Advisor: Robert A. Bambara, Ph.D.

Now: Senior Director, Molecular Diagnostics Business Unit at Quidel

Ping Yi

Studies on Mechanisms of Estrogen Receptor Subtype-Specific Transcription Regulation

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Professor at Baylor College of Medicine

2000

Negin Martin, Ph.D.

Intramolecular Interactions among Transmembrane Regions of STE2, a G Protein Coupled Receptor in Yeast Saccharomyces cerevisiae

Advisor: Mark E. Dumont, Ph.D.

Now: Biologist at National Institute of Environmental Health and Sciences

1999

LuAnn Leavitt, Ph.D.

Dominant Negative Mutations of the a-Factor Receptor Encoded by the STE2 Gene of the Yeast Saccharomyces cerevisiae

Advisor: Mark E. Dumont, Ph.D.

Now: TBC at TBC

Ganesan Sathya

Characterization of Estrogen-induced Synergistic Response at Multiple EstrogenResponsive Elements (EREs)

Advisor: Robert A. Bambara, Ph.D.

Now: Chair of the Mentors, Advisors and Peers program at Women in Bio

1998

Jin Kim

Mechanisms of viral recombination by Human Immunodeficiency Virus Type I reverse transcriptase

Advisor: Robert A. Bambara, Ph.D.

Jeffrey Rumbaugh, Ph.D.

Biochemical mechanisms of DNA replication and repair and of HIV replication using mammalian enzymes

Advisor: Robert A. Bambara, Ph.D.

Now: Assistant Professor, Neurology at Johns Hopkins University