Cholesterol in the Blood
Facts about cholesterol
Cholesterol is a fat-like, waxy substance that can be found in all parts of your body.
It helps your body make cell membranes, many hormones, and vitamin D. The cholesterol
in your blood comes from 2 sources: the foods you eat and your liver. Your liver makes
all the cholesterol your body needs.
Cholesterol and other fats are carried in your bloodstream as spherical particles
called lipoproteins. The 2 most commonly known lipoproteins are low-density lipoproteins
(LDL) and high-density lipoproteins (HDL).
What is LDL (low-density lipoprotein) cholesterol?
What is HDL (high-density lipoprotein) cholesterol?
LDL ("bad") cholesterol is a type of fat in the blood that contains the most cholesterol.
It can contribute to plaque buildup in the arteries (atherosclerosis). This is linked
to higher risk for heart attack and stroke.
You want your LDL to be low. To help lower it:
HDL ("good") cholesterol helps to remove cholesterol from the blood. This keeps plaque
from building up in your arteries.
You want your HDL to be as high as possible. Some people can raise HDL by:
Exercising for at least 30 minutes 5 times a week
Quitting smoking, if you smoke
Not eating saturated fats
Others may need medicine. Because raising HDL is complicated, you should work with
your healthcare provider on a treatment plan.
Checking your blood cholesterol level
A cholesterol screening is an overall look at the fats in your blood. Screenings help
find people at risk for heart disease. It is important to have what is called a full
lipid profile to show the actual levels of each type of fat in your blood: LDL, HDL,
triglycerides, and others. Talk with your healthcare provider about when to have this
Your cholesterol is checked with a simple blood test. The results tell you how much
cholesterol you have in your blood. Get checked as often as your healthcare provider
suggests. Start monitoring your cholesterol levels and other risk factors regularly
at age 20. The American Heart Association (AHA) advises following up every 4 to 6
years. Check it earlier if you have an increased risk for either high cholesterol
or heart disease. If you have diabetes or high cholesterol, you may need your blood
tested as often as every 3 months. Discuss your numbers with your healthcare provider.
You may need to be checked more often.
What is a healthy blood cholesterol level?
High blood cholesterol is a major risk factor for heart disease and stroke. You can
lower your risk by getting more exercise, losing weight if you are overweight, quitting
smoking, and eating a healthy diet. But blood cholesterol is very specific to each
person. Your healthcare provider will determine your total cholesterol and LDL goals
based on other risk factors. For that reason, a full lipid profile is an important
part of your health history and important information for your healthcare provider
What treatments are available for high cholesterol?
Medical treatment may include:
Changing risk factors. Some risk factors that can be changed include lack of exercise and poor eating habits.
Cholesterol-lowering medicines. Medicines are used to lower fats in the blood, particularly LDL cholesterol. Statins
are a group of medicines that can do this. They include simvastatin, atorvastatin,
and pravastatin. Two other types of medicines that lower cholesterol levels are bile
acid sequestrants such as colesevelam, cholestyramine, and colestipol, and nicotinic
Statistics about cholesterol
High cholesterol is a risk for many Americans. Consider these statistics:
According to the AHA, about 95 million American adults have total blood cholesterol
levels of 200 mg/dL and higher. Of those, about 28.5 million American adults have
a level of 240 or above.
High cholesterol levels early in life may play a role in developing atherosclerosis
as an adult.
According to the AHA, high blood cholesterol that runs in families will affect the
future of an unknown but probably large number of children.
What are triglycerides?
Triglycerides are another class of fat found in the bloodstream. The bulk of your
body's fat tissue is in the form of triglycerides.
Triglyceride levels and heart disease
The link between triglycerides and heart disease is being studied. But many people
with high triglycerides also have other risk factors, like high LDL levels or low
What causes elevated triglyceride levels?
High triglyceride levels are linked with health conditions like diabetes, hypothyroidism,
kidney disease, or liver disease. Dietary causes of high triglyceride levels may include drinking
a lot of alcohol, eating foods containing saturated fat and trans fat, and eating
lots of carbohydrates.