Recent Publications

• 1. Xiao B
  2. Liu Y
  3. Chandrasiri I
  4. Overby C
  5. Benoit DSW
  Impact of Nanoparticle Physicochemical Properties on Protein Corona and Macrophage Polarization.; ACS applied materials & interfaces. 2023 Mar 14.
• 1. Adjei-Sowah E
  2. Benoit DSW
  3. Loiselle AE
  Drug Delivery Approaches to Improve Tendon Healing.; Tissue engineering. Part B, Reviews. 2023 Mar 08.
• 1. Ito T
  2. Sims KR
  3. Liu Y
  4. Xiang Z
  5. Arthur RA
  6. Hara AT
  7. Koo H
  8. Benoit DSW
  9. Klein MI
  Farnesol delivery via polymeric nanoparticle carriers inhibits cariogenic cross-kingdom biofilms and prevents enamel demineralization.; Molecular oral microbiology. 2022 Jul 20.
• 1. Fraser D
  2. Nguyen T
  3. Kotelsky A
  4. Lee W
  5. Buckley M
  6. Benoit DSW
  Hydrogel Swelling-Mediated Strain Induces Cell Alignment at Dentin Interfaces.; ACS biomaterials science & engineering. 2022 Jul 06.
• 1. Piraino LR
  2. Benoit DSW
  3. DeLouise LA
  Optimizing Soluble Cues for Salivary Gland Tissue Mimetics Using a Design of Experiments (DoE) Approach.; Cells; Vol 11(12). 2022 Jun 18.
• 1. Song Y
  2. Uchida H
  3. Sharipol A
  4. Piraino L
  5. Mereness JA
  6. Ingalls MH
  7. Rebhahn J
  8. Newlands SD
  9. DeLouise LA
  10. Ovitt CE
  11. Benoit DSW
  Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 5(1). 2022 Mar 30.
• 1. Song Y
  2. Sharipol A
  3. Uchida H
  4. Ingalls MH
  5. Piraino L
  6. Mereness JA
  7. Moyston T
  8. DeLouise LA
  9. Ovitt CE
  10. Benoit DSW
  Encapsulation of Primary Salivary Gland Acinar Cell Clusters and Intercalated Ducts (AIDUCs) within Matrix Metalloproteinase (MMP)-Degradable Hydrogels to Maintain Tissue Structure and Function.; Advanced healthcare materials. 2022 Jan 06.
• 1. Roncari Rocha G
  2. Sims KR
  3. Xiao B
  4. Klein MI
  5. Benoit DSW
  Nanoparticle carrier co-delivery of complementary antibiofilm drugs abrogates dual species cariogenic biofilm formation in vitro.; Journal of oral microbiology; Vol 14(1). 2022.
• 1. Ackun-Farmmer MA
  2. Alwaseem H
  3. Counts M
  4. Bortz A
  5. Giovani S
  6. Frisch BJ
  7. Fasan R
  8. Benoit DSW
  Nanoparticle-Mediated Delivery of Micheliolide Analogs to Eliminate Leukemic Stem Cells in the Bone Marrow.; Advanced therapeutics; Vol 5(1). 2022 Jan.
• 1. Li Y
  2. Fraser D
  3. Mereness J
  4. Van Hove A
  5. Basu S
  6. Newman M
  7. Benoit DSW
  Tissue Engineered Neurovascularization Strategies for Craniofacial Tissue Regeneration.; ACS applied bio materials. 2021 Nov 29.
• 1. Zhu G
  2. Lin Y
  3. Ge T
  4. Singh S
  5. Liu H
  6. Fan L
  7. Wang S
  8. Rhen J
  9. Jiang D
  10. Lyu Y
  11. Yin Y
  12. Li X
  13. Benoit DSW
  14. Li W
  15. Xu Y
  16. Pang J
  A novel inhibitory peptide of Dll4-Notch1 signaling and its proangiogenic functions.; British journal of pharmacology. 2021 Nov 18.
• 1. Ackun-Farmmer MA
  2. Overby CT
  3. Haws BE
  4. Choe R
  5. Benoit DSW
  Biomaterials for Orthopaedic Diagnostics and Theranostics.; Current opinion in biomedical engineering; Vol 19. 2021 Sep.
• 1. Ackun-Farmmer MA
  2. Xiao B
  3. Newman MR
  4. Benoit DSW
  Macrophage depletion increases target specificity of bone-targeted nanoparticles.; Journal of biomedical materials research. Part A. 2021 Jul 28.
• 1. Piraino LR
  2. Benoit DSW
  3. DeLouise LA
  Salivary Gland Tissue Engineering Approaches: State of the Art and Future Directions.; Cells; Vol 10(7). 2021 Jul 08.
• 1. Manian KV
  2. Galloway CA
  3. Dalvi S
  4. Emanuel AA
  5. Mereness JA
  6. Black W
  7. Winschel L
  8. Soto C
  9. Li Y
  10. Song Y
  11. DeMaria W
  12. Kumar A
  13. Slukvin I
  14. Schwartz MP
  15. Murphy WL
  16. Anand-Apte B
  17. Chung M
  18. Benoit DSW
  19. Singh R
  3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.; Cell stem cell; Vol 28(5). 2021 May 06.
• 1. Song Y
  2. Uchida H
  3. Sharipol A
  4. Piraino L
  5. Mereness JA
  6. Ingalls MH
  7. Rebhahn J
  8. Newlands SD
  9. DeLouise LA
  10. Ovitt CE
  11. Benoit DSW
  Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 4(1). 2021 Apr 30.
• 1. Ackun-Farmmer MA
  2. Soto CA
  3. Lesch ML
  4. Byun D
  5. Yang L
  6. Calvi LM
  7. Benoit DSW
  8. Frisch BJ
  Reduction of leukemic burden via bone-targeted nanoparticle delivery of an inhibitor of C-chemokine (C-C motif) ligand 3 (CCL3) signaling.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 35(4). 2021 Apr.
• 1. Manian KV
  2. Galloway CA
  3. Dalvi S
  4. Emanuel AA
  5. Mereness JA
  6. Black W
  7. Winschel L
  8. Soto C
  9. Li Y
  10. Song Y
  11. DeMaria W
  12. Kumar A
  13. Slukvin I
  14. Schwartz MP
  15. Murphy WL
  16. Anand-Apte B
  17. Chung M
  18. Benoit DSW
  19. Singh R
  3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.; Cell stem cell. 2021 Mar 29.
• 1. Song Y
  2. Uchida H
  3. Sharipol A
  4. Piraino L
  5. Mereness JA
  6. Ingalls MH
  7. Rebhahn J
  8. Newlands SD
  9. DeLouise LA
  10. Ovitt CE
  11. Benoit DSW
  Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 4(1). 2021 Mar 19.
• 1. Simon-Soro A
  2. Kim D
  3. Li Y
  4. Liu Y
  5. Ito T
  6. Sims KR
  7. Benoit DSW
  8. Bittinger K
  9. Koo H
  Impact of the repurposed drug thonzonium bromide on host oral-gut microbiomes.; NPJ biofilms and microbiomes; Vol 7(1). 2021 Jan 22.
• 1. Fraser D
  2. Nguyen T
  3. Benoit DSW
  Matrix Control of Periodontal Ligament Cell Activity Via Synthetic Hydrogel Scaffolds.; Tissue engineering. Part A. 2020 Dec 09.
• 1. Li Y
  2. Hoffman MD
  3. Benoit DSW
  Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host neurovasculature.; Biomaterials; Vol 268. 2020 Nov 19.
• 1. Ackun-Farmmer MA
  2. Alatise KL
  3. Cross G
  4. Benoit DSW
  Ligand Density Controls C-Type Lectin-Like Molecule-1 Receptor-Specific Uptake of Polymer Nanoparticles.; Advanced biosystems. 2020 Oct 19.
• 1. Ren J
  2. Ramirez GA
  3. Proctor AR
  4. Wu TT
  5. Benoit DSW
  6. Choe R
  Spatial frequency domain imaging for the longitudinal monitoring of vascularization during mouse femoral graft healing.; Biomedical optics express; Vol 11(10). 2020 Oct 01.
• 1. Sims KR
  2. Maceren JP
  3. Liu Y
  4. Rocha GR
  5. Koo H
  6. Benoit DSW
  Dual Antibacterial Drug-Loaded Nanoparticles Synergistically Improve Treatment of Streptococcus mutans Biofilms.; Acta biomaterialia. 2020 Aug 24.
• 1. Sims KR
  2. He B
  3. Koo H
  4. Benoit DSW
  Electrostatic Interactions Enable Nanoparticle Delivery of the Flavonoid Myricetin.; ACS omega; Vol 5(22). 2020 Jun 09.
• 1. Malcolm DW
  2. Wang Y
  3. Overby C
  4. Newman M
  5. Benoit DSW
  Delivery of RNAi-Based Therapeutics for Bone Regeneration.; Current osteoporosis reports; Vol 18(3). 2020 Jun.
• 1. Wang Y
  2. Newman MR
  3. Ackun-Farmmer M
  4. Baranello MP
  5. Sheu TJ
  6. Puzas JE
  7. Benoit DSW
  Correction to Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing.; ACS nano. 2020 Mar 25.
• 1. Ren J
  2. Han S
  3. Proctor AR
  4. Desa DE
  5. Ramirez GA
  6. Ching-Roa VRD
  7. Majeski JB
  8. Dar IA
  9. Barber NE
  10. Forti AM
  11. Benoit DSW
  12. Choe R
  Longitudinal 3D Blood Flow Distribution Provided by Diffuse Correlation Tomography during Bone Healing in a Murine Fracture Model.; Photochemistry and photobiology; Vol 96(2). 2020 Mar.
• 1. Shubin AD
  2. Sharipol A
  3. Felong TJ
  4. Weng PL
  5. Schutrum BE
  6. Joe DS
  7. Aure MH
  8. Benoit DSW
  9. Ovitt CE
  Stress or injury induces cellular plasticity in salivary gland acinar cells.; Cell and tissue research. 2020 Jan 04.
• 1. Sims KR
  2. Maceren JP
  3. Strand AI
  4. He B
  5. Overby C
  6. Benoit DSW
  Rigor and reproducibility in polymer nanoparticle synthesis and characterization.; RSC advances; Vol 10(5). 2020.
• 1. Freeberg MAT
  2. Easa A
  3. Lillis JA
  4. Benoit DSW
  5. van Wijnen AJ
  6. Awad HA
  Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019 Aug 19.
• 1. Benoit DSW
  2. Sims KR
  3. Fraser D
  Nanoparticles for Oral Biofilm Treatments.; ACS nano. 2019 Apr 29.
• 1. Sims KR
  2. Liu Y
  3. Hwang G
  4. Jung HI
  5. Koo H
  6. Benoit DSW
  Enhanced design and formulation of nanoparticles for anti-biofilm drug delivery.; Nanoscale. 2018 Dec 07.
• 1. Varghese JJ
  2. Hansen ME
  3. Sharipol A
  4. Ingalls MH
  5. Ormanoski MA
  6. Newlands SD
  7. Ovitt CE
  8. Benoit DSW
  Salivary gland cell aggregates are derived from self-organization of acinar lineage cells.; Archives of oral biology; Vol 97. 2018 Oct 22.
• 1. Wang Y
  2. Zhang S
  3. Benoit DSW
  Degradable poly(ethylene glycol) (PEG)-based hydrogels for spatiotemporal control of siRNA/nanoparticle delivery.; Journal of controlled release : official journal of the Controlled Release Society; Vol 287. 2018 Oct 10.
• 1. Newman MR
  2. Russell SG
  3. Benoit DSW
  Controlled organocatalyzed d,l-lactide ring-opening polymerizations: synthesis of low molecular weight oligomers.; RSC advances; Vol 8(51). 2018 Aug 14.
• 1. Newman MR
  2. Benoit DSW
  In Vivo Translation of Peptide-Targeted Drug Delivery Systems Discovered by Phage Display.; Bioconjugate chemistry; Vol 29(7). 2018 Jul 18.
• 1. Varghese JJ
  2. Schmale IL
  3. Hansen ME
  4. Newlands SD
  5. Benoit DSW
  6. Ovitt CE
  Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation.; Journal of visualized experiments : JoVE. 2018 May 04.
• 1. Varghese JJ
  2. Schmale IL
  3. Wang Y
  4. Hansen ME
  5. Newlands SD
  6. Ovitt CE
  7. Benoit DSW
  Retroductal Nanoparticle Injection to the Murine Submandibular Gland.; Journal of visualized experiments : JoVE. 2018 May 03.
• 1. Freeberg MAT
  2. Farhat YM
  3. Easa A
  4. Kallenbach JG
  5. Malcolm DW
  6. Buckley MR
  7. Benoit DSW
  8. Awad HA
  Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy.; Scientific reports; Vol 8(1). 2018 Apr 11.
• 1. Varghese JJ
  2. Schmale IL
  3. Mickelson D
  4. Hansen ME
  5. Newlands SD
  6. Benoit DSW
  7. Korshunov VA
  8. Ovitt CE
  Localized Delivery of Amifostine Enhances Salivary Gland Radioprotection.; Journal of dental research. 2018 Apr 01.
• 1. Wang Y
  2. Newman MR
  3. Benoit DSW
  Development of Controlled Drug Delivery Systems for Bone Fracture-Targeted Therapeutic Delivery: A Review.; European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2018 Feb 19.
• 1. Newman MR
  2. Russell SG
  3. Schmitt CS
  4. Marozas IA
  5. Sheu TJ
  6. Puzas JE
  7. Benoit DSW
  Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues.; Biomacromolecules; Vol 19(1). 2018 Jan 08.
• 1. Han S
  2. Proctor AR
  3. Ren J
  4. Benoit DSW
  5. Choe R
  Temporal blood flow changes measured by diffuse correlation tomography predict murine femoral graft healing.; PloS one; Vol 13(5). 2018.
• 1. Malcolm DW
  2. Varghese JJ
  3. Sorrells JE
  4. Ovitt CE
  5. Benoit DSW
  The Effects of Biological Fluids on Colloidal Stability and siRNA Delivery of a pH-Responsive Micellar Nanoparticle Delivery System.; ACS nano. 2017 Dec 12.
• 1. Malcolm DW
  2. Freeberg MAT
  3. Wang Y
  4. Sims KR
  5. Awad HA
  6. Benoit DSW
  Diblock Copolymer Hydrophobicity Facilitates Efficient Gene Silencing and Cytocompatible Nanoparticle-Mediated siRNA Delivery to Musculoskeletal Cell Types.; Biomacromolecules; Vol 18(11). 2017 Nov 13.
• 1. Vella JB
  2. Trombetta RP
  3. Hoffman MD
  4. Inzana J
  5. Awad H
  6. Benoit DSW
  Three dimensional printed calcium phosphate and poly(caprolactone) composites with improved mechanical properties and preserved microstructure.; Journal of biomedical materials research. Part A. 2017 Oct 16.
• 1. Wang Y
  2. Newman MR
  3. Ackun-Farmmer M
  4. Baranello MP
  5. Sheu TJ
  6. Puzas JE
  7. Benoit DSW
  Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing.; ACS nano; Vol 11(9). 2017 Sep 26.
• 1. Wang Y
  2. Malcolm DW
  3. Benoit DSW
  Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing.; Biomaterials; Vol 139. 2017 Sep.