URMC / Labs / Benoit Lab / Publications Recent Publications Xiao BLiu YChandrasiri IOverby CBenoit DSW Impact of Nanoparticle Physicochemical Properties on Protein Corona and Macrophage Polarization.; ACS applied materials & interfaces. 2023 Mar 14. Adjei-Sowah EBenoit DSWLoiselle AE Drug Delivery Approaches to Improve Tendon Healing.; Tissue engineering. Part B, Reviews. 2023 Mar 08. Ito TSims KRLiu YXiang ZArthur RAHara ATKoo HBenoit DSWKlein MI Farnesol delivery via polymeric nanoparticle carriers inhibits cariogenic cross-kingdom biofilms and prevents enamel demineralization.; Molecular oral microbiology. 2022 Jul 20. Fraser DNguyen TKotelsky ALee WBuckley MBenoit DSW Hydrogel Swelling-Mediated Strain Induces Cell Alignment at Dentin Interfaces.; ACS biomaterials science & engineering. 2022 Jul 06. Piraino LRBenoit DSWDeLouise LA Optimizing Soluble Cues for Salivary Gland Tissue Mimetics Using a Design of Experiments (DoE) Approach.; Cells; Vol 11(12). 2022 Jun 18. Song YUchida HSharipol APiraino LMereness JAIngalls MHRebhahn JNewlands SDDeLouise LAOvitt CEBenoit DSW Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 5(1). 2022 Mar 30. Song YSharipol AUchida HIngalls MHPiraino LMereness JAMoyston TDeLouise LAOvitt CEBenoit DSW Encapsulation of Primary Salivary Gland Acinar Cell Clusters and Intercalated Ducts (AIDUCs) within Matrix Metalloproteinase (MMP)-Degradable Hydrogels to Maintain Tissue Structure and Function.; Advanced healthcare materials. 2022 Jan 06. Roncari Rocha GSims KRXiao BKlein MIBenoit DSW Nanoparticle carrier co-delivery of complementary antibiofilm drugs abrogates dual species cariogenic biofilm formation in vitro.; Journal of oral microbiology; Vol 14(1). 2022. Ackun-Farmmer MAAlwaseem HCounts MBortz AGiovani SFrisch BJFasan RBenoit DSW Nanoparticle-Mediated Delivery of Micheliolide Analogs to Eliminate Leukemic Stem Cells in the Bone Marrow.; Advanced therapeutics; Vol 5(1). 2022 Jan. Li YFraser DMereness JVan Hove ABasu SNewman MBenoit DSW Tissue Engineered Neurovascularization Strategies for Craniofacial Tissue Regeneration.; ACS applied bio materials. 2021 Nov 29. Zhu GLin YGe TSingh SLiu HFan LWang SRhen JJiang DLyu YYin YLi XBenoit DSWLi WXu YPang J A novel inhibitory peptide of Dll4-Notch1 signaling and its proangiogenic functions.; British journal of pharmacology. 2021 Nov 18. Ackun-Farmmer MAOverby CTHaws BEChoe RBenoit DSW Biomaterials for Orthopaedic Diagnostics and Theranostics.; Current opinion in biomedical engineering; Vol 19. 2021 Sep. Ackun-Farmmer MAXiao BNewman MRBenoit DSW Macrophage depletion increases target specificity of bone-targeted nanoparticles.; Journal of biomedical materials research. Part A. 2021 Jul 28. Piraino LRBenoit DSWDeLouise LA Salivary Gland Tissue Engineering Approaches: State of the Art and Future Directions.; Cells; Vol 10(7). 2021 Jul 08. Manian KVGalloway CADalvi SEmanuel AAMereness JABlack WWinschel LSoto CLi YSong YDeMaria WKumar ASlukvin ISchwartz MPMurphy WLAnand-Apte BChung MBenoit DSWSingh R 3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.; Cell stem cell; Vol 28(5). 2021 May 06. Song YUchida HSharipol APiraino LMereness JAIngalls MHRebhahn JNewlands SDDeLouise LAOvitt CEBenoit DSW Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 4(1). 2021 Apr 30. Ackun-Farmmer MASoto CALesch MLByun DYang LCalvi LMBenoit DSWFrisch BJ Reduction of leukemic burden via bone-targeted nanoparticle delivery of an inhibitor of C-chemokine (C-C motif) ligand 3 (CCL3) signaling.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 35(4). 2021 Apr. Manian KVGalloway CADalvi SEmanuel AAMereness JABlack WWinschel LSoto CLi YSong YDeMaria WKumar ASlukvin ISchwartz MPMurphy WLAnand-Apte BChung MBenoit DSWSingh R 3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.; Cell stem cell. 2021 Mar 29. Song YUchida HSharipol APiraino LMereness JAIngalls MHRebhahn JNewlands SDDeLouise LAOvitt CEBenoit DSW Development of a functional salivary gland tissue chip with potential for high-content drug screening.; Communications biology; Vol 4(1). 2021 Mar 19. Simon-Soro AKim DLi YLiu YIto TSims KRBenoit DSWBittinger KKoo H Impact of the repurposed drug thonzonium bromide on host oral-gut microbiomes.; NPJ biofilms and microbiomes; Vol 7(1). 2021 Jan 22. Fraser DNguyen TBenoit DSW Matrix Control of Periodontal Ligament Cell Activity Via Synthetic Hydrogel Scaffolds.; Tissue engineering. Part A. 2020 Dec 09. Li YHoffman MDBenoit DSW Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host neurovasculature.; Biomaterials; Vol 268. 2020 Nov 19. Ackun-Farmmer MAAlatise KLCross GBenoit DSW Ligand Density Controls C-Type Lectin-Like Molecule-1 Receptor-Specific Uptake of Polymer Nanoparticles.; Advanced biosystems. 2020 Oct 19. Ren JRamirez GAProctor ARWu TTBenoit DSWChoe R Spatial frequency domain imaging for the longitudinal monitoring of vascularization during mouse femoral graft healing.; Biomedical optics express; Vol 11(10). 2020 Oct 01. Sims KRMaceren JPLiu YRocha GRKoo HBenoit DSW Dual Antibacterial Drug-Loaded Nanoparticles Synergistically Improve Treatment of Streptococcus mutans Biofilms.; Acta biomaterialia. 2020 Aug 24. Sims KRHe BKoo HBenoit DSW Electrostatic Interactions Enable Nanoparticle Delivery of the Flavonoid Myricetin.; ACS omega; Vol 5(22). 2020 Jun 09. Malcolm DWWang YOverby CNewman MBenoit DSW Delivery of RNAi-Based Therapeutics for Bone Regeneration.; Current osteoporosis reports; Vol 18(3). 2020 Jun. Wang YNewman MRAckun-Farmmer MBaranello MPSheu TJPuzas JEBenoit DSW Correction to Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing.; ACS nano. 2020 Mar 25. Ren JHan SProctor ARDesa DERamirez GAChing-Roa VRDMajeski JBDar IABarber NEForti AMBenoit DSWChoe R Longitudinal 3D Blood Flow Distribution Provided by Diffuse Correlation Tomography during Bone Healing in a Murine Fracture Model.; Photochemistry and photobiology; Vol 96(2). 2020 Mar. Shubin ADSharipol AFelong TJWeng PLSchutrum BEJoe DSAure MHBenoit DSWOvitt CE Stress or injury induces cellular plasticity in salivary gland acinar cells.; Cell and tissue research. 2020 Jan 04. Sims KRMaceren JPStrand AIHe BOverby CBenoit DSW Rigor and reproducibility in polymer nanoparticle synthesis and characterization.; RSC advances; Vol 10(5). 2020. Freeberg MATEasa ALillis JABenoit DSWvan Wijnen AJAwad HA Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019 Aug 19. Benoit DSWSims KRFraser D Nanoparticles for Oral Biofilm Treatments.; ACS nano. 2019 Apr 29. Sims KRLiu YHwang GJung HIKoo HBenoit DSW Enhanced design and formulation of nanoparticles for anti-biofilm drug delivery.; Nanoscale. 2018 Dec 07. Varghese JJHansen MESharipol AIngalls MHOrmanoski MANewlands SDOvitt CEBenoit DSW Salivary gland cell aggregates are derived from self-organization of acinar lineage cells.; Archives of oral biology; Vol 97. 2018 Oct 22. Wang YZhang SBenoit DSW Degradable poly(ethylene glycol) (PEG)-based hydrogels for spatiotemporal control of siRNA/nanoparticle delivery.; Journal of controlled release : official journal of the Controlled Release Society; Vol 287. 2018 Oct 10. Newman MRRussell SGBenoit DSW Controlled organocatalyzed d,l-lactide ring-opening polymerizations: synthesis of low molecular weight oligomers.; RSC advances; Vol 8(51). 2018 Aug 14. Newman MRBenoit DSW In Vivo Translation of Peptide-Targeted Drug Delivery Systems Discovered by Phage Display.; Bioconjugate chemistry; Vol 29(7). 2018 Jul 18. Varghese JJSchmale ILHansen MENewlands SDBenoit DSWOvitt CE Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation.; Journal of visualized experiments : JoVE. 2018 May 04. Varghese JJSchmale ILWang YHansen MENewlands SDOvitt CEBenoit DSW Retroductal Nanoparticle Injection to the Murine Submandibular Gland.; Journal of visualized experiments : JoVE. 2018 May 03. Freeberg MATFarhat YMEasa AKallenbach JGMalcolm DWBuckley MRBenoit DSWAwad HA Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy.; Scientific reports; Vol 8(1). 2018 Apr 11. Varghese JJSchmale ILMickelson DHansen MENewlands SDBenoit DSWKorshunov VAOvitt CE Localized Delivery of Amifostine Enhances Salivary Gland Radioprotection.; Journal of dental research. 2018 Apr 01. Wang YNewman MRBenoit DSW Development of Controlled Drug Delivery Systems for Bone Fracture-Targeted Therapeutic Delivery: A Review.; European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2018 Feb 19. Newman MRRussell SGSchmitt CSMarozas IASheu TJPuzas JEBenoit DSW Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues.; Biomacromolecules; Vol 19(1). 2018 Jan 08. Han SProctor ARRen JBenoit DSWChoe R Temporal blood flow changes measured by diffuse correlation tomography predict murine femoral graft healing.; PloS one; Vol 13(5). 2018. Malcolm DWVarghese JJSorrells JEOvitt CEBenoit DSW The Effects of Biological Fluids on Colloidal Stability and siRNA Delivery of a pH-Responsive Micellar Nanoparticle Delivery System.; ACS nano. 2017 Dec 12. Malcolm DWFreeberg MATWang YSims KRAwad HABenoit DSW Diblock Copolymer Hydrophobicity Facilitates Efficient Gene Silencing and Cytocompatible Nanoparticle-Mediated siRNA Delivery to Musculoskeletal Cell Types.; Biomacromolecules; Vol 18(11). 2017 Nov 13. Vella JBTrombetta RPHoffman MDInzana JAwad HBenoit DSW Three dimensional printed calcium phosphate and poly(caprolactone) composites with improved mechanical properties and preserved microstructure.; Journal of biomedical materials research. Part A. 2017 Oct 16. Wang YNewman MRAckun-Farmmer MBaranello MPSheu TJPuzas JEBenoit DSW Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing.; ACS nano; Vol 11(9). 2017 Sep 26. Wang YMalcolm DWBenoit DSW Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing.; Biomaterials; Vol 139. 2017 Sep.