URochester Medicine / Labs / Siyu Sun Lab / Publications

Recent Publications

1. Sun S
2. Greenbaum BD
Viral Mimicry by Repeats Mediates Evolutionary Trade-Offs in Cancer-Immune Coevolution.; Cancer discovery; Vol 16(8), pp. 1489-1493. 2026 Aug 03.
1. Šulc P
2. Di Gioacchino A
3. Solovyov A
4. Sun S
5. Martis S
6. Marhon SA
7. Lindholm HT
8. Chen R
9. Hosseini A
10. Jiang H
11. Ly BH
12. Taylor MS
13. Mehdipour P
14. Abdel-Wahab O
15. Rusk N
16. Vabret N
17. LaCava J
18. De Carvalho DD
19. Monasson R
20. Cocco S
21. Greenbaum BD
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape.; Cell genomics; Vol 5(12), pp. 101011. 2025 Sep 24.
1. You E
2. Patel BK
3. Rojas AS
4. Sun S
5. Danaher P
6. Ho NI
7. Phillips IE
8. Raabe MJ
9. Song Y
10. Xu KH
11. Kocher JR
12. Richieri PM
13. Shin P
14. Taylor MS
15. Nieman LT
16. Greenbaum BD
17. Ting DT
LINE-1 ORF1p Mimics Viral Innate Immune Evasion Mechanisms in Pancreatic Ductal Adenocarcinoma.; Cancer discovery; Vol 15(5), pp. 1063-1082. 2025 May 02.
1. Ishak CA
2. Marhon SA
3. Tchrakian N
4. Hodgson A
5. Loo Yau H
6. Gonzaga IM
7. Peralta M
8. Lungu IM
9. Gomez S
10. Liang SB
11. Shen SY
12. Chen R
13. Chen J
14. Chatterjee B
15. Wanniarachchi KN
16. Lee J
17. Zehrbach N
18. Hosseini A
19. Mehdipour P
20. Sun S
21. Solovyov A
22. Ettayebi I
23. Francis KE
24. He A
25. Wu T
26. Feng S
27. da Silva Medina T
28. Campos de Almeida F
29. Bayani J
30. Li J
31. MacDonald S
32. Wang Y
33. Garcia SS
34. Arthofer E
35. Diab N
36. Srivastava A
37. Austin PT
38. Sabatini PJB
39. Greenbaum BD
40. O'Brien CA
41. Shepherd TG
42. Tsao MS
43. Chiappinelli KB
44. Oza AM
45. Clarke BA
46. Rottapel R
47. Lheureux S
48. De Carvalho DD
Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion.; Cancer discovery; Vol 15(4), pp. 793-817. 2025 Apr 02.
1. Brodeur MN
2. Dopeso H
3. Zhu Y
4. Longhini ALF
5. Gazzo A
6. Sun S
7. Koche RP
8. Qu R
9. Rosenberg L
10. Hamard PJ
11. Bykov Y
12. Green H
13. Gusain L
14. Chiappinelli KB
15. Ozsoy MA
16. Chui MH
17. Basili T
18. Gardner R
19. Walderich S
20. DeStanchina E
21. Greenbaum B
22. Gönen M
23. Vabret N
24. Weigelt B
25. Zamarin D
Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity.; Science advances; Vol 10(49), pp. eadk4851. 2024 Dec 04.
1. Sun S
2. You E
3. Hong J
4. Hoyos D
5. Del Priore I
6. Tsanov KM
7. Mattagajasingh O
8. Di Gioacchino A
9. Marhon SA
10. Chacon-Barahona J
11. Li H
12. Jiang H
13. Hozeifi S
14. Rosas-Bringas O
15. Xu KH
16. Song Y
17. Lang ER
18. Rojas AS
19. Nieman LT
20. Patel BK
21. Murali R
22. Chanda P
23. Karacay A
24. Vabret N
25. De Carvalho DD
26. Zenklusen D
27. LaCava J
28. Lowe SW
29. Ting DT
30. Iacobuzio-Donahue CA
31. Solovyov A
32. Greenbaum BD
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.; Immunity; Vol 57(12), pp. 2879-2894.e11. 2024 Nov 21.
1. You E
2. Danaher P
3. Lu C
4. Sun S
5. Zou L
6. Phillips IE
7. Rojas AS
8. Ho NI
9. Song Y
10. Raabe MJ
11. Xu KH
12. Richieri PM
13. Li H
14. Aston N
15. Porter RL
16. Patel BK
17. Nieman LT
18. Schurman N
19. Hudson BM
20. North K
21. Church SE
22. Deshpande V
23. Liss AS
24. Kim TK
25. Cui Y
26. Kim Y
27. Greenbaum BD
28. Aryee MJ
29. Ting DT
Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer.; Cell; Vol 187(25), pp. 7232-7247.e23. 2024 Oct 08.
1. You E
2. Patel B
3. Rojas A
4. Ho N
5. Sun S
6. Raabe M
7. Song Y
8. Phillips L
9. Xu K
10. Richieri P
11. Nieman L
12. Greenbaum B
13. Ting D
Human LINE-1 ORF1p retrotransposition independent function in pancreatic cancer; Cancer Research; Vol 84(6 Supplement). 2024 Jan 01.
1. Brodeur M
2. Sun S
3. Zhu Y
4. Greenbaum B
5. Weigelt B
6. Zamarin D
Abstract B007: Endogenous retrotransposable elements induction in SMARCA4-deficient ovarian cancer is associated with immunomodulatory changes in the tumor microenvironment; Cancer Research; Vol 82(23 Supplement 2). 2022 Jan 01.
1. Porter RL
2. Sun S
3. Flores MN
4. Berzolla E
5. You E
6. Phillips IE
7. Kc N
8. Desai N
9. Tai EC
10. Szabolcs A
11. Lang ER
12. Pankaj A
13. Raabe MJ
14. Thapar V
15. Xu KH
16. Nieman LT
17. Rabe DC
18. Kolin DL
19. Stover EH
20. Pepin D
21. Stott SL
22. Deshpande V
23. Liu JF
24. Solovyov A
25. Matulonis UA
26. Greenbaum BD
27. Ting DT
Satellite repeat RNA expression in epithelial ovarian cancer associates with a tumor-immunosuppressive phenotype.; The Journal of clinical investigation; Vol 132(16). 2022 Aug 15.
1. Sulc P
2. Gioacchino AD
3. Solovyov A
4. Marhon SA
5. Sun S
6. Lindholm HT
7. Chen R
8. Hosseini A
9. Jiang H
10. Ly B
11. Mehdipour P
12. Abdel-Wahab O
13. Vabret N
14. Lacava J
15. de Carvalho DD
16. Monasson R
17. Cocco S
18. Greenbaum BD
Repeats mimic immunostimulatory viral features across a vast evolutionary landscape; bioRxiv. 2021 Jan 01.
1. Sun S
2. Gresham D
Cellular quiescence in budding yeast.; Yeast (Chichester, England); Vol 38(1), pp. 12-29. 2021 Jan 25.
1. Sun S
2. Baryshnikova A
3. Brandt N
4. Gresham D
Genetic interaction profiles of regulatory kinases differ between environmental conditions and cellular states.; Molecular systems biology; Vol 16(5), pp. e9167. 2020 May.
1. Yang J
2. Sun S
3. Zhang S
4. Gonzalez M
5. Dong Q
6. Chi Z
7. Chen YH
8. Li F
Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation.; PLoS genetics; Vol 14(8), pp. e1007572. 2018 Aug 08.
1. Gonzalez M
2. He H
3. Dong Q
4. Sun S
5. Li F
Ectopic centromere nucleation by CENP--a in fission yeast.; Genetics; Vol 198(4), pp. 1433-46. 2014 Oct 07.
1. Gonzalez M
2. He H
3. Sun S
4. Li C
5. Li F
Cell cycle-dependent deposition of CENP-A requires the Dos1/2-Cdc20 complex.; Proceedings of the National Academy of Sciences of the United States of America; Vol 110(2), pp. 606-11. 2012 Dec 24.