Welcome to the Zhu Lab
Our lab works with retroviruses (HIV-1, MLV, etc.) and focuses on identifying new host antiviral factors and deciphering viral antagonism of host defense. We use a combination of molecular, genomic, and cellular techniques to study the interactions between retroviruses and host cells. Particularly, we are interested in:
- Epigenetic silencing and latency of HIV-1 DNA
- Translation and stability control of HIV-1 mRNA
Comprehensive understanding mechanisms of host-retrovirus interactions will provide unique insights into gene regulation and potential opportunities for new antiviral therapies.
Yiping Zhu, Ph.D.
Principal Investigator
- The TRAF3-DYRK1A-RAD54L2 complex maintains ACE2 expression to promote SARS-CoV-2 infection.; Journal of virology; Vol 98(5), pp. e0034724. 2024 Apr 23.
- PTEN Mediates the Silencing of Unintegrated HIV-1 DNA.; Viruses; Vol 16(2). 2024 Feb 14.
- HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit.; Viruses; Vol 15(2). 2023 Feb 08.
Contact Us
Yiping Zhu Lab
KMRB 3-9812
601 Elmwood Ave
Rochester, NY 14642