URMC / Research / Mass Spectrometry Resource Lab / Services Services Consultation Research project design and planning Proper sample preparation for subsequent MS-based analysis Assistance with data interpretation, grant writing, and publication Sample Preparation Sample clean-up and processing: proteolytic digest fractionation precipitation, extraction, depletion desalting SDS-PAGE gel electrophoresis and staining Mass Spectrometry Protein and peptide identification in purified samples or complex mixtures Protein Quantitation Small molecule quantitation PTM identification Intact protein analysis Data Analysis Proteome Discoverer data analysis software, using MASCOT and SEQUEST search algorithms LC-Quan software for small molecule quantitation