URMC / Research / Mass Spectrometry Resource Lab / Services Services Consultation Research project design and planning Proper sample preparation for subsequent MS-based analysis Assistance with data interpretation, grant writing and publication Sample Preparation Sample clean-up and processing: extraction, depletion, proteolytic digest, fractionation, desalting, etc. SDS-PAGE gel electrophoresis and staining Mass Spectrometry Protein and peptide identification in purified samples or complex mixtures Protein Quantitation: Label free, chemical isotopic labeling, Isobaric tags, SILAC labeled proteins Small molecule quantitation PTM identification Intact protein analysis Data Analysis Qualitative and quantitative data analysis, using the Proteome Discoverer software package Small molecule quantitation