Project Examples

Examples of projects that have involved T32 trainees include studies of:

• The developmental effects of prenatal exposure to methylmercury from maternal fish consumption in the Seychelles Child Development Study, which now consists of three cohorts with multiple outcomes measured at multiple ages
• The associations between air pollution exposure and biomarkers thought to indicate increased risk of future cardiac events, in a cardiac rehabilitation study
• The joint effects of lead and stress on multiple neurotransmitters in five brain regions in rats
• The effects of perfluorinated alkyl substances on ovarian hormone concentrations in fertile women
• RNA sequencing to quantify the effect of dioxin exposure on CD8+ T-cell gene expression accounting for an unknown mixture of responders and non-responders. 

These projects have led to methodological research on topics such as multiple longitudinal outcomes, structural equation models, causal inference, and exposure effects on mixtures of hormone trajectories, and has been the basis of a number of PhD theses.