URMC / Cardiovascular Research Institute / Research / Yan Lab / Lab Members Lab Members Principal InvestigatorChen Yan, Ph.D.CVRIPhone: (585) 276-9792Email ChenResearch Interest: Regulation and Function of Cyclic Nucleotide Phosphodiesterases in the Cardiovascular SystemPostdoctoral ScholarsSi (Vivian) Chen, Ph.D.Postdoctoral AssociateResearch Interest: Focuses on the role of cyclic nucleotide phosphodiesterase 10A (PDE10A) in regulating cardiac hypertrophy and dysfunction.Research StaffSarah GreenlyLaboratory TechnicianYishuai Zhang, Ph.D.Staff MemberGraduate StudentsChongyang Zhang, M.S.CMPP Cellular and Molecular Pharmacology and Physiology Ph.D. ProgramResearch Interest: Focuses on the role of cyclic nucleotide phosphodiesterase 1C in smooth muscle cell remodeling in human vessel diseases.