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Research Labs

Our faculty, staff and students work as a team to create an atmosphere of learning, growing and life-long friendships. If you are interested in joining our team, please feel free to contact us for more information.

Charles J. Lowenstein, M.D.Dr. Charles Lowenstein

Dr. Lowenstein's research is focused on vascular biology. One team of researchers explores mechanisms of exocytosis, through which endothelial cells release pro-inflammatory and pro-thrombotic mediators. A second group of scientists study how platelets communicate with endothelial cells. A third area of research involves an exploration of the role of microRNA in endothelial cells. A fourth team investigates how nitric oxide affects vascular inflammation. View Lowenstein Lab page

Bradford C. Berk, M.D., Ph.D.Bradford Berk

Dr. Berk's laboratory is focused on defining the mechanisms by which cells in the vascular wall respond to hemodynamic and hormonal stimuli.
View Berk Lab page

 

Scott James Cameron, Ph.D., M.D.Bradford Berk

Our laboratory has funding from the National Institute of Heath to study signal transduction pathways in the cardiovascular system, and we apply this to the study of thrombotic disorders of the arterial and venous vasculature.
View Cameron Lab page

Jian Fu, B.Med., Ph.D.Bradford Berk

Dr. Fu's research focus is on elucidating of the biochemical and biological roles of SM20, the orthologue of EGLN-3, with a specific emphasis on deciphering the effect of SM20 on the differentiation and development of skeletal muscle.
View Fu Lab page

Zheng-Gen Jin, Ph.D.Zheng-Gen Jin

Dr. Jin’s research has been focused on molecular regulation of vascular endothelial function. Vascular endothelial cells in blood vessels produce a number of vasodilator and vasoconstrictor substances that not only physiologically regulate vasomotor tone and vascular homeostasis, but also mediate the recruitment and activity of inflammatory cells and the propensity towards atherosclerotic lesion formation and thrombosis in the pathological condition. View Jin Lab page

Slava Korshunov, Ph.D.Slava Korshunov

Dr. Korshunov's major focus is the understanding of mechanisms that regulate the structure of blood vessels (a process we call “vascular remodeling”) could prevent cardiovascular morbidity and mortality in humans. View Korshunov Lab page

Coeli Lopes, Ph.D.Coeli Lopes

The major focus of Dr. Lopes current work involves the regulation of the slow delayed rectifier-like current (IKs) in the heart and the pathogenesis of the Long QT (LQT1) syndrome. View Lopes Lab page

Joseph Miano, Ph.D.Joseph Miano

My lab utilizes state-of-the-art methods in molecular biology, genetics, genomics, and computational biology to acquire in-depth knowledge on the transcriptional regulation of gene expression and the functional role of regulatory proteins in Alzheimer’s disease and vascular occlusive disease. View Miano Lab page

Craig Morrell, DVM, Ph.D.Craig Morrell

Platelets have two major functions: hemostastis/thrombosis and an immune regulatory function. My laboratory uses in vitro techniques and in vivo mouse models to study both important platelet functions. View Morrell Lab page

Jinjiang Pang, B.Med., Ph.D.Jinjiang Pang

Angiogenesis, the formation of new blood vessels from existing ones, is a critical event for tissue development and repair, as well as being associated with many diseases (e.g. bronchopulmonary dysplasia, pulmonary artery hypertension, ischemic cardiomyopathy, retinopathy and tumor growth). View Pang Lab page

Eric Small, Ph.D.Eric Small

Research in the Small Lab is focused on understanding the molecular mechanisms that control how a cell responds to its surroundings during development or following tissue injury. View Small Lab page

Jane Sottile, Ph.D.Jane Sottile

Remodeling of extracellular matrices occurs during development, wound healing, and in a variety of pathological processes including atherosclerosis, ischemic injury, and angiogenesis. Perturbing matrix remodeling events by preventing the turnover of extracellular matrix molecules, or by increasing the levels of matrix degrading proteases or inhibitors has been shown to result in fibrosis, arthritis, reduced angiogenesis, and developmental abnormalities. View Sottile Lab page

Chen Yan, Ph.D.Chen Yan

Regulation and function of cyclic nucleotide phosphodiesterases in the cardiovascular system. Second messenger cyclic nucleotides (cAMP and cGMP) regulate many signaling pathways in the cardiovascular system. View Yan Lab page

Peng Yao, Ph.D.Chen Yan

Regulatory non-coding RNAs and RNA-binding proteins (RBPs) are important research areas in gene regulation and RNA biology. Our laboratory is interested in the understanding of pathophysiological function and molecular mechanism of new non-coding RNAs (and RBPs) and new modes of gene regulation in cardiac system and cardiovascular disease. View Yao Lab page