Recent Publications

• 1. Bez M
  2. Sheyn D
  3. Tawackoli W
  4. Avalos P
  5. Shapiro G
  6. Giaconi JC
  7. Da X
  8. David SB
  9. Gavrity J
  10. Awad HA
  11. Bae HW
  12. Ley EJ
  13. Kremen TJ
  14. Gazit Z
  15. Ferrara KW
  16. Pelled G
  17. Gazit D
  (2017 May 17). In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs. Science translational medicine.
• 1. Feng G
  2. Ochoa M
  3. Maher JR
  4. Awad HA
  5. Berger AJ
  (2017 May 02). Sensitivity of spatially offset Raman spectroscopy (SORS) to subcortical bone tissue. Journal of biophotonics.
• 1. Beier EE
  2. Sheu TJ
  3. Resseguie EA
  4. Takahata M
  5. Awad HA
  6. Cory-Slechta DA
  7. Puzas JE
  (2017). Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice. Bone research.
• 1. de Mesy Bentley KL
  2. Trombetta R
  3. Nishitani K
  4. Bello-Irizarry SN
  5. Ninomiya M
  6. Zhang L
  7. Chung HL
  8. McGrath JL
  9. Daiss JL
  10. Awad HA
  11. Kates SL
  12. Schwarz EM
  (2016 Dec 08). Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
• 1. Trombetta R
  2. Inzana JA
  3. Schwarz EM
  4. Kates SL
  5. Awad HA
  (2016 Jun 20). 3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery. Annals of biomedical engineering.
• 1. Inzana JA
  2. Schwarz EM
  3. Kates SL
  4. Awad HA
  (2016 Mar). Biomaterials approaches to treating implant-associated osteomyelitis. Biomaterials.
• 1. Yaseen Z
  2. English C
  3. Stanbury SJ
  4. Chen T
  5. Messing S
  6. Awad H
  7. Elfar JC
  (2015 Jul). The Effect of the Epitendinous Suture on Gliding in a Cadaveric Model of Zone II Flexor Tendon Repair. The Journal of hand surgery.
• 1. Loiselle AE
  2. Yukata K
  3. Geary MB
  4. Kondabolu S
  5. Shi S
  6. Jonason JH
  7. Awad HA
  8. O'Keefe RJ
  (2015 Jun). Development of antisense oligonucleotide (ASO) technology against Tgf-β signaling to prevent scarring during flexor tendon repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
• 1. Wang C
  2. Shen J
  3. Yukata K
  4. Inzana JA
  5. O'Keefe RJ
  6. Awad HA
  7. Hilton MJ
  (2015 Apr). Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation. Bone.
• 1. Geary MB
  2. English C
  3. Yaseen Z
  4. Stanbury S
  5. Awad H
  6. Elfar JC
  (2015 Apr). Flexor digitorum superficialis repair outside the A2 pulley after zone II laceration: gliding and bowstringing. The Journal of hand surgery.
• 1. Zhang M
  2. Feigenson M
  3. Sheu TJ
  4. Awad HA
  5. Schwarz EM
  6. Jonason JH
  7. Loiselle AE
  8. O'Keefe RJ
  (2015 Mar). Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength. Bone.
• 1. Inzana JA
  2. Schwarz EM
  3. Kates SL
  4. Awad HA
  (2015 Mar). A novel murine model of established Staphylococcal bone infection in the presence of a fracture fixation plate to study therapies utilizing antibiotic-laden spacers after revision surgery. Bone.
• 1. Farhat YM
  2. Al-Maliki AA
  3. Easa A
  4. O'Keefe RJ
  5. Schwarz EM
  6. Awad HA
  (2015 Feb). TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair. Journal of cellular physiology.
• 1. Lee DJ
  2. Southgate RD
  3. Farhat YM
  4. Loiselle AE
  5. Hammert WC
  6. Awad HA
  7. O'Keefe RJ
  (2015 Jan). Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
• 1. Geary MB
  2. Orner CA
  3. Bawany F
  4. Awad HA
  5. Hammert WC
  6. O'Keefe RJ
  7. Loiselle AE
  (2015). Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair. PloS one.
• 1. Inzana JA
  2. Trombetta RP
  3. Schwarz EM
  4. Kates SL
  5. Awad HA
  (2015). 3D printed bioceramics for dual antibiotic delivery to treat implant-associated bone infection. European cells & materials.
• 1. Yukata K
  2. Xie C
  3. Li TF
  4. Takahata M
  5. Hoak D
  6. Kondabolu S
  7. Zhang X
  8. Awad HA
  9. Schwarz EM
  10. Beck CA
  11. Jonason JH
  12. O'Keefe RJ
  (2014 May). Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment. Bone.
• 1. Inzana JA
  2. Olvera D
  3. Fuller SM
  4. Kelly JP
  5. Graeve OA
  6. Schwarz EM
  7. Kates SL
  8. Awad HA
  (2014 Apr). 3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration. Biomaterials.
• 1. Long T
  2. Zhu Z
  3. Awad HA
  4. Schwarz EM
  5. Hilton MJ
  6. Dong Y
  (2014 Mar). The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice. Biomaterials.
• 1. Stanbury SJ
  2. English C
  3. Yaseen Z
  4. Reed JD
  5. Chen T
  6. Awad H
  7. Elfar JC
  (2014 Mar). The Effect of Pulley Reconstruction on Maximum Flexion, Bowstringing, and Gliding Coefficient in the Setting of Zone II Repair of FDS and FDP: a Cadaveric Investigation. Hand (New York, N.Y.).
• 1. Juneja SC
  2. Vonica A
  3. Zeiss C
  4. Lezon-Geyda K
  5. Yatsula B
  6. Sell DR
  7. Monnier VM
  8. Lin S
  9. Ardito T
  10. Eyre D
  11. Reynolds D
  12. Yao Z
  13. Awad HA
  14. Yu H
  15. Wilson M
  16. Honnons S
  17. Boyce BF
  18. Xing L
  19. Zhang Y
  20. Perkins AS
  (2014 Mar). Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia. Bone.
• 1. David MA
  2. Jones KH
  3. Inzana JA
  4. Zuscik MJ
  5. Awad HA
  6. Mooney RA
  (2014). Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes. PloS one.
• 1. Brown ML
  2. Yukata K
  3. Farnsworth CW
  4. Chen DG
  5. Awad H
  6. Hilton MJ
  7. O'Keefe RJ
  8. Xing L
  9. Mooney RA
  10. Zuscik MJ
  (2014). Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus. PloS one.
• 1. Hasslund S
  2. Dadali T
  3. Ulrich-Vinther M
  4. Søballe K
  5. Schwarz EM
  6. Awad HA
  (2014). Freeze-dried allograft-mediated gene or protein delivery of growth and differentiation factor 5 reduces reconstructed murine flexor tendon adhesions. Journal of tissue engineering.
• 1. Hasslund S
  2. O'Keefe RJ
  3. Awad HA
  (2014). A mouse model of flexor tendon repair. Methods in molecular biology (Clifton, N.J.).
• 1. Chaubey A
  2. Grawe B
  3. Meganck JA
  4. Dyment N
  5. Inzana J
  6. Jiang X
  7. Connolley C
  8. Awad H
  9. Rowe D
  10. Kenter K
  11. Goldstein SA
  12. Butler D
  (2013 Dec). Structural and biomechanical responses of osseous healing: a novel murine nonunion model. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology.
• 1. Inzana JA
  2. Kung M
  3. Shu L
  4. Hamada D
  5. Xing LP
  6. Zuscik MJ
  7. Awad HA
  8. Mooney RA
  (2013 Nov). Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur. Bone.
• 1. Maher JR
  2. Inzana JA
  3. Awad HA
  4. Berger AJ
  (2013 Jul). Overconstrained library-based fitting method reveals age- and disease-related differences in transcutaneous Raman spectra of murine bones. Journal of biomedical optics.
• 1. Chu JY
  2. Chen T
  3. Awad HA
  4. Elfar J
  5. Hammert WC
  (2013 Jun). Comparison of an all-inside suture technique with traditional pull-out suture and suture anchor repair techniques for flexor digitorum profundus attachment to bone. The Journal of hand surgery.
• 1. Madsen W
  2. Yaseen Z
  3. LaFrance R
  4. Chen T
  5. Awad H
  6. Maloney M
  7. Voloshin I
  (2013 Jun). Addition of a suture anchor for coracoclavicular fixation to a superior locking plate improves stability of type IIB distal clavicle fractures. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.
• 1. Chen T
  2. Hilton MJ
  3. Brown EB
  4. Zuscik MJ
  5. Awad HA
  (2013 May). Engineering superficial zone features in tissue engineered cartilage. Biotechnology and bioengineering.
• 1. Dhillon RS
  2. Xie C
  3. Tyler W
  4. Calvi LM
  5. Awad HA
  6. Zuscik MJ
  7. O'Keefe RJ
  8. Schwarz EM
  (2013 Mar). PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
• 1. Inzana JA
  2. Maher JR
  3. Takahata M
  4. Schwarz EM
  5. Berger AJ
  6. Awad HA
  (2013 Feb 22). Bone fragility beyond strength and mineral density: Raman spectroscopy predicts femoral fracture toughness in a murine model of rheumatoid arthritis. Journal of biomechanics.
• 1. Juneja SC
  2. Schwarz EM
  3. O'Keefe RJ
  4. Awad HA
  (2013). Cellular and molecular factors in flexor tendon repair and adhesions: a histological and gene expression analysis. Connective tissue research.
• 1. Takahata M
  2. Maher JR
  3. Juneja SC
  4. Inzana J
  5. Xing L
  6. Schwarz EM
  7. Berger AJ
  8. Awad HA
  (2012 Nov). Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: implications for insufficiency fracture risk. Arthritis and rheumatism.
• 1. Chen T
  2. Buckley M
  3. Cohen I
  4. Bonassar L
  5. Awad HA
  (2012 May). Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels. Biomechanics and modeling in mechanobiology.
• 1. Takahata M
  2. Awad HA
  3. O'Keefe RJ
  4. Bukata SV
  5. Schwarz EM
  (2012 Mar). Endogenous tissue engineering: PTH therapy for skeletal repair. Cell and tissue research.
• 1. Takahata M
  2. Schwarz EM
  3. Chen T
  4. O'Keefe RJ
  5. Awad HA
  (2012 Jan). Delayed short-course treatment with teriparatide (PTH(1-34)) improves femoral allograft healing by enhancing intramembranous bone formation at the graft-host junction. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
• 1. Loiselle AE
  2. Frisch BJ
  3. Wolenski M
  4. Jacobson JA
  5. Calvi LM
  6. Schwarz EM
  7. Awad HA
  8. O'Keefe RJ
  (2012). Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury. PloS one.
• 1. Farhat YM
  2. Al-Maliki AA
  3. Chen T
  4. Juneja SC
  5. Schwarz EM
  6. O'Keefe RJ
  7. Awad HA
  (2012). Gene expression analysis of the pleiotropic effects of TGF-β1 in an in vitro model of flexor tendon healing. PloS one.
• 1. Zhao L
  2. Huang J
  3. Zhang H
  4. Wang Y
  5. Matesic LE
  6. Takahata M
  7. Awad H
  8. Chen D
  9. Xing L
  (2011 Oct). Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1. Stem cells (Dayton, Ohio).
• 1. Sampson ER
  2. Hilton MJ
  3. Tian Y
  4. Chen D
  5. Schwarz EM
  6. Mooney RA
  7. Bukata SV
  8. O'Keefe RJ
  9. Awad H
  10. Puzas JE
  11. Rosier RN
  12. Zuscik MJ
  (2011 Sep 21). Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis. Science translational medicine.
• 1. Papuga MO
  2. Kwok E
  3. You Z
  4. Rubery PT
  5. Dougherty PE
  6. Pryhuber G
  7. Beck CA
  8. Hilton MJ
  9. Awad HA
  10. Schwarz EM
  (2011 Sep). TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease. Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
• 1. Yazici C
  2. Takahata M
  3. Reynolds DG
  4. Xie C
  5. Samulski RJ
  6. Samulski J
  7. Beecham EJ
  8. Gertzman AA
  9. Spilker M
  10. Zhang X
  11. O'Keefe RJ
  12. Awad HA
  13. Schwarz EM
  (2011 Aug). Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur. Molecular therapy : the journal of the American Society of Gene Therapy.
• 1. Maher JR
  2. Takahata M
  3. Awad HA
  4. Berger AJ
  (2011 Aug). Raman spectroscopy detects deterioration in biomechanical properties of bone in a glucocorticoid-treated mouse model of rheumatoid arthritis. Journal of biomedical optics.
• 1. Sampson ER
  2. Beck CA
  3. Ketz J
  4. Canary KL
  5. Hilton MJ
  6. Awad H
  7. Schwarz EM
  8. Chen D
  9. O'Keefe RJ
  10. Rosier RN
  11. Zuscik MJ
  (2011 Aug). Establishment of an index with increased sensitivity for assessing murine arthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
• 1. Yee M
  2. White RJ
  3. Awad HA
  4. Bates WA
  5. McGrath-Morrow SA
  6. O'Reilly MA
  (2011 Jun). Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice. The American journal of pathology.
• 1. Katzel EB
  2. Koltz PF
  3. Tierney R
  4. Williams JP
  5. Awad HA
  6. O'keefe RJ
  7. Langstein HN
  (2011 Jun). The impact of Smad3 loss of function on TGF-β signaling and radiation-induced capsular contracture. Plastic and reconstructive surgery.
• 1. Katzel EB
  2. Wolenski M
  3. Loiselle AE
  4. Basile P
  5. Flick LM
  6. Langstein HN
  7. Hilton MJ
  8. Awad HA
  9. Hammert WC
  10. O'Keefe RJ
  (2011 May). Impact of Smad3 loss of function on scarring and adhesion formation during tendon healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
• 1. Zhang M
  2. Ho HC
  3. Sheu TJ
  4. Breyer MD
  5. Flick LM
  6. Jonason JH
  7. Awad HA
  8. Schwarz EM
  9. O'Keefe RJ
  (2011 Apr). EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.