Recent Publications

• 1. Trombetta RP
  2. Ninomiya MJ
  3. El-Atawneh IM
  4. Knapp EK
  5. de Mesy Bentley KL
  6. Dunman PM
  7. Schwarz EM
  8. Kates SL
  9. Awad HA
  Calcium Phosphate Spacers for the Local Delivery of Sitafloxacin and Rifampin to Treat Orthopedic Infections: Efficacy and Proof of Concept in a Mouse Model of Single-Stage Revision of Device-Associated Osteomyelitis.; Pharmaceutics; Vol 11(2). 2019 Feb 22.
• 1. Chen RE
  2. Soin SP
  3. El-Shaar R
  4. Awad HA
  5. Maloney MD
  6. Voloshin I
  Reconstruction of the Superior Glenoid Labrum With Biceps Tendon Autograft: A Cadaveric Biomechanical Study.; Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association; Vol 35(2). 2019 Feb.
• 1. Trombetta RP
  2. Dunman PM
  3. Schwarz EM
  4. Kates SL
  5. Awad HA
  A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against Staphylococcus aureus Small-Colony Variants.; mSphere; Vol 3(5). 2018 Oct 31.
• 1. Childs S
  2. McVicker Z
  3. Trombetta R
  4. Awad H
  5. Elfar J
  6. Giordano B
  Patient-Specific 3-Dimensional Modeling and Its Use for Preoperative Counseling of Patients Undergoing Hip Arthroscopy.; Orthopaedic journal of sports medicine; Vol 6(9). 2018 Sep.
• 1. Schott EM
  2. Farnsworth CW
  3. Grier A
  4. Lillis JA
  5. Soniwala S
  6. Dadourian GH
  7. Bell RD
  8. Doolittle ML
  9. Villani DA
  10. Awad H
  11. Ketz JP
  12. Kamal F
  13. Ackert-Bicknell C
  14. Ashton JM
  15. Gill SR
  16. Mooney RA
  17. Zuscik MJ
  Targeting the gut microbiome to treat the osteoarthritis of obesity.; JCI insight; Vol 3(8). 2018 Apr 19.
• 1. Freeberg MAT
  2. Farhat YM
  3. Easa A
  4. Kallenbach JG
  5. Malcolm DW
  6. Buckley MR
  7. Benoit DSW
  8. Awad HA
  Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy.; Scientific reports; Vol 8(1). 2018 Apr 11.
• 1. Bez M
  2. Sheyn D
  3. Tawackoli W
  4. Avalos P
  5. Shapiro G
  6. Giaconi JC
  7. Da X
  8. David SB
  9. Gavrity J
  10. Awad HA
  11. Bae HW
  12. Ley EJ
  13. Kremen TJ
  14. Gazit Z
  15. Ferrara KW
  16. Pelled G
  17. Gazit D
  In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs.; Science translational medicine; Vol 9(390). 2017 May 17.
• 1. Feng G
  2. Ochoa M
  3. Maher JR
  4. Awad HA
  5. Berger AJ
  Sensitivity of spatially offset Raman spectroscopy (SORS) to subcortical bone tissue.; Journal of biophotonics. 2017 May 02.
• 1. Beier EE
  2. Sheu TJ
  3. Resseguie EA
  4. Takahata M
  5. Awad HA
  6. Cory-Slechta DA
  7. Puzas JE
  Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice.; Bone research; Vol 5. 2017.
• 1. de Mesy Bentley KL
  2. Trombetta R
  3. Nishitani K
  4. Bello-Irizarry SN
  5. Ninomiya M
  6. Zhang L
  7. Chung HL
  8. McGrath JL
  9. Daiss JL
  10. Awad HA
  11. Kates SL
  12. Schwarz EM
  Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2016 Dec 08.
• 1. Trombetta R
  2. Inzana JA
  3. Schwarz EM
  4. Kates SL
  5. Awad HA
  3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery.; Annals of biomedical engineering. 2016 Jun 20.
• 1. Inzana JA
  2. Schwarz EM
  3. Kates SL
  4. Awad HA
  Biomaterials approaches to treating implant-associated osteomyelitis.; Biomaterials; Vol 81. 2016 Mar.
• 1. Yaseen Z
  2. English C
  3. Stanbury SJ
  4. Chen T
  5. Messing S
  6. Awad H
  7. Elfar JC
  The Effect of the Epitendinous Suture on Gliding in a Cadaveric Model of Zone II Flexor Tendon Repair.; The Journal of hand surgery; Vol 40(7). 2015 Jul.
• 1. Loiselle AE
  2. Yukata K
  3. Geary MB
  4. Kondabolu S
  5. Shi S
  6. Jonason JH
  7. Awad HA
  8. O'Keefe RJ
  Development of antisense oligonucleotide (ASO) technology against Tgf-β signaling to prevent scarring during flexor tendon repair.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 33(6). 2015 Jun.
• 1. Wang C
  2. Shen J
  3. Yukata K
  4. Inzana JA
  5. O'Keefe RJ
  6. Awad HA
  7. Hilton MJ
  Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation.; Bone; Vol 73. 2015 Apr.
• 1. Geary MB
  2. English C
  3. Yaseen Z
  4. Stanbury S
  5. Awad H
  6. Elfar JC
  Flexor digitorum superficialis repair outside the A2 pulley after zone II laceration: gliding and bowstringing.; The Journal of hand surgery; Vol 40(4). 2015 Apr.
• 1. Zhang M
  2. Feigenson M
  3. Sheu TJ
  4. Awad HA
  5. Schwarz EM
  6. Jonason JH
  7. Loiselle AE
  8. O'Keefe RJ
  Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength.; Bone; Vol 72. 2015 Mar.
• 1. Inzana JA
  2. Schwarz EM
  3. Kates SL
  4. Awad HA
  A novel murine model of established Staphylococcal bone infection in the presence of a fracture fixation plate to study therapies utilizing antibiotic-laden spacers after revision surgery.; Bone; Vol 72. 2015 Mar.
• 1. Farhat YM
  2. Al-Maliki AA
  3. Easa A
  4. O'Keefe RJ
  5. Schwarz EM
  6. Awad HA
  TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair.; Journal of cellular physiology; Vol 230(2). 2015 Feb.
• 1. Lee DJ
  2. Southgate RD
  3. Farhat YM
  4. Loiselle AE
  5. Hammert WC
  6. Awad HA
  7. O'Keefe RJ
  Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 33(1). 2015 Jan.
• 1. Geary MB
  2. Orner CA
  3. Bawany F
  4. Awad HA
  5. Hammert WC
  6. O'Keefe RJ
  7. Loiselle AE
  Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair.; PloS one; Vol 10(8). 2015.
• 1. Inzana JA
  2. Trombetta RP
  3. Schwarz EM
  4. Kates SL
  5. Awad HA
  3D printed bioceramics for dual antibiotic delivery to treat implant-associated bone infection.; European cells & materials; Vol 30. 2015.
• 1. Yukata K
  2. Xie C
  3. Li TF
  4. Takahata M
  5. Hoak D
  6. Kondabolu S
  7. Zhang X
  8. Awad HA
  9. Schwarz EM
  10. Beck CA
  11. Jonason JH
  12. O'Keefe RJ
  Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment.; Bone; Vol 62. 2014 May.
• 1. Inzana JA
  2. Olvera D
  3. Fuller SM
  4. Kelly JP
  5. Graeve OA
  6. Schwarz EM
  7. Kates SL
  8. Awad HA
  3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration.; Biomaterials; Vol 35(13). 2014 Apr.
• 1. Long T
  2. Zhu Z
  3. Awad HA
  4. Schwarz EM
  5. Hilton MJ
  6. Dong Y
  The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice.; Biomaterials; Vol 35(9). 2014 Mar.
• 1. Stanbury SJ
  2. English C
  3. Yaseen Z
  4. Reed JD
  5. Chen T
  6. Awad H
  7. Elfar JC
  The Effect of Pulley Reconstruction on Maximum Flexion, Bowstringing, and Gliding Coefficient in the Setting of Zone II Repair of FDS and FDP: a Cadaveric Investigation.; Hand (New York, N.Y.); Vol 9(1). 2014 Mar.
• 1. Juneja SC
  2. Vonica A
  3. Zeiss C
  4. Lezon-Geyda K
  5. Yatsula B
  6. Sell DR
  7. Monnier VM
  8. Lin S
  9. Ardito T
  10. Eyre D
  11. Reynolds D
  12. Yao Z
  13. Awad HA
  14. Yu H
  15. Wilson M
  16. Honnons S
  17. Boyce BF
  18. Xing L
  19. Zhang Y
  20. Perkins AS
  Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.; Bone; Vol 60. 2014 Mar.
• 1. David MA
  2. Jones KH
  3. Inzana JA
  4. Zuscik MJ
  5. Awad HA
  6. Mooney RA
  Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes.; PloS one; Vol 9(3). 2014.
• 1. Brown ML
  2. Yukata K
  3. Farnsworth CW
  4. Chen DG
  5. Awad H
  6. Hilton MJ
  7. O'Keefe RJ
  8. Xing L
  9. Mooney RA
  10. Zuscik MJ
  Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.; PloS one; Vol 9(6). 2014.
• 1. Hasslund S
  2. Dadali T
  3. Ulrich-Vinther M
  4. Søballe K
  5. Schwarz EM
  6. Awad HA
  Freeze-dried allograft-mediated gene or protein delivery of growth and differentiation factor 5 reduces reconstructed murine flexor tendon adhesions.; Journal of tissue engineering; Vol 5. 2014.
• 1. Hasslund S
  2. O'Keefe RJ
  3. Awad HA
  A mouse model of flexor tendon repair.; Methods in molecular biology (Clifton, N.J.); Vol 1130. 2014.
• 1. Chaubey A
  2. Grawe B
  3. Meganck JA
  4. Dyment N
  5. Inzana J
  6. Jiang X
  7. Connolley C
  8. Awad H
  9. Rowe D
  10. Kenter K
  11. Goldstein SA
  12. Butler D
  Structural and biomechanical responses of osseous healing: a novel murine nonunion model.; Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology; Vol 14(4). 2013 Dec.
• 1. Inzana JA
  2. Kung M
  3. Shu L
  4. Hamada D
  5. Xing LP
  6. Zuscik MJ
  7. Awad HA
  8. Mooney RA
  Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur.; Bone; Vol 57(1). 2013 Nov.
• 1. Maher JR
  2. Inzana JA
  3. Awad HA
  4. Berger AJ
  Overconstrained library-based fitting method reveals age- and disease-related differences in transcutaneous Raman spectra of murine bones.; Journal of biomedical optics; Vol 18(7). 2013 Jul.
• 1. Chu JY
  2. Chen T
  3. Awad HA
  4. Elfar J
  5. Hammert WC
  Comparison of an all-inside suture technique with traditional pull-out suture and suture anchor repair techniques for flexor digitorum profundus attachment to bone.; The Journal of hand surgery; Vol 38(6). 2013 Jun.
• 1. Madsen W
  2. Yaseen Z
  3. LaFrance R
  4. Chen T
  5. Awad H
  6. Maloney M
  7. Voloshin I
  Addition of a suture anchor for coracoclavicular fixation to a superior locking plate improves stability of type IIB distal clavicle fractures.; Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association; Vol 29(6). 2013 Jun.
• 1. Chen T
  2. Hilton MJ
  3. Brown EB
  4. Zuscik MJ
  5. Awad HA
  Engineering superficial zone features in tissue engineered cartilage.; Biotechnology and bioengineering; Vol 110(5). 2013 May.
• 1. Dhillon RS
  2. Xie C
  3. Tyler W
  4. Calvi LM
  5. Awad HA
  6. Zuscik MJ
  7. O'Keefe RJ
  8. Schwarz EM
  PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 28(3). 2013 Mar.
• 1. Inzana JA
  2. Maher JR
  3. Takahata M
  4. Schwarz EM
  5. Berger AJ
  6. Awad HA
  Bone fragility beyond strength and mineral density: Raman spectroscopy predicts femoral fracture toughness in a murine model of rheumatoid arthritis.; Journal of biomechanics; Vol 46(4). 2013 Feb 22.
• 1. Juneja SC
  2. Schwarz EM
  3. O'Keefe RJ
  4. Awad HA
  Cellular and molecular factors in flexor tendon repair and adhesions: a histological and gene expression analysis.; Connective tissue research; Vol 54(3). 2013.
• 1. Takahata M
  2. Maher JR
  3. Juneja SC
  4. Inzana J
  5. Xing L
  6. Schwarz EM
  7. Berger AJ
  8. Awad HA
  Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: implications for insufficiency fracture risk.; Arthritis and rheumatism; Vol 64(11). 2012 Nov.
• 1. Chen T
  2. Buckley M
  3. Cohen I
  4. Bonassar L
  5. Awad HA
  Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels.; Biomechanics and modeling in mechanobiology; Vol 11(5). 2012 May.
• 1. Takahata M
  2. Awad HA
  3. O'Keefe RJ
  4. Bukata SV
  5. Schwarz EM
  Endogenous tissue engineering: PTH therapy for skeletal repair.; Cell and tissue research; Vol 347(3). 2012 Mar.
• 1. Takahata M
  2. Schwarz EM
  3. Chen T
  4. O'Keefe RJ
  5. Awad HA
  Delayed short-course treatment with teriparatide (PTH(1-34)) improves femoral allograft healing by enhancing intramembranous bone formation at the graft-host junction.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 27(1). 2012 Jan.
• 1. Loiselle AE
  2. Frisch BJ
  3. Wolenski M
  4. Jacobson JA
  5. Calvi LM
  6. Schwarz EM
  7. Awad HA
  8. O'Keefe RJ
  Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury.; PloS one; Vol 7(7). 2012.
• 1. Farhat YM
  2. Al-Maliki AA
  3. Chen T
  4. Juneja SC
  5. Schwarz EM
  6. O'Keefe RJ
  7. Awad HA
  Gene expression analysis of the pleiotropic effects of TGF-β1 in an in vitro model of flexor tendon healing.; PloS one; Vol 7(12). 2012.
• 1. Zhao L
  2. Huang J
  3. Zhang H
  4. Wang Y
  5. Matesic LE
  6. Takahata M
  7. Awad H
  8. Chen D
  9. Xing L
  Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1.; Stem cells (Dayton, Ohio); Vol 29(10). 2011 Oct.
• 1. Sampson ER
  2. Hilton MJ
  3. Tian Y
  4. Chen D
  5. Schwarz EM
  6. Mooney RA
  7. Bukata SV
  8. O'Keefe RJ
  9. Awad H
  10. Puzas JE
  11. Rosier RN
  12. Zuscik MJ
  Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.; Science translational medicine; Vol 3(101). 2011 Sep 21.
• 1. Papuga MO
  2. Kwok E
  3. You Z
  4. Rubery PT
  5. Dougherty PE
  6. Pryhuber G
  7. Beck CA
  8. Hilton MJ
  9. Awad HA
  10. Schwarz EM
  TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 29(9). 2011 Sep.
• 1. Yazici C
  2. Takahata M
  3. Reynolds DG
  4. Xie C
  5. Samulski RJ
  6. Samulski J
  7. Beecham EJ
  8. Gertzman AA
  9. Spilker M
  10. Zhang X
  11. O'Keefe RJ
  12. Awad HA
  13. Schwarz EM
  Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur.; Molecular therapy : the journal of the American Society of Gene Therapy; Vol 19(8). 2011 Aug.