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  • Rahman Research 1
  • Rahman Research 2
  • Rahman Research 5
  • Rahman Research 5
  • Rahman Research 5

Rahman Lab

Welcome to the Rahman Lab

My laboratory is interested in understanding the redox signaling, mechanism of proinflammatory gene expression by studying the chromatin remodeling-epigenetic changes (histone acetylation/deacetylation and DNA methylation), involvement of anti-inflammatory and anti-aging proteins sirtuins, HDACs, DNA damage/repair, and cellular senescence in chronic lung inflammatory diseases including COPD. Recent research includes in understanding the role of sirtuins/HDACs in aging and accelerated decline in lung function, cellular senescence, and regulation of circadian genes. Our long-term goal is to understand the cellular and molecular mechanisms involved in the pathogenesis of chronic inflammatory lung diseases caused by environmental toxicants (tobacco smoke, e-cigarettes, oxidants/aldehydes), identifying molecular targets, and the potential benefit of therapeutic interventions in airways disease.

New Book

Inflammation, Advancing Age and Nutrition

Inflammation, Advancing Age and Nutrition, 1st Edition

The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine.

Purchase at the Elsevier Store

Irfan Rahman, Ph.D.

Irfan Rahman, Ph.D.

Principal Investigator

Publications

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Contact Us

  Rahman Lab
601 Elmwood Ave
MRBX 3-11001
Rochester, NY 14642